Today's Healthcare Pulse
Abridge teams with Eli Lilly and Nvidia to expand AI scribe platform
Abridge announced a partnership with Nvidia to build a foundation model for clinical conversations and secured a strategic investment from Eli Lilly to boost evidence‑based care. The AI scribe provider now serves more than 300 health systems and is extending its platform to integrate with payers.
Also developing:
By the numbers: Kardigan targets $1.4B valuation in US IPO
Who’s the Agent? Building the Identity Layer Healthcare AI Actually Needs
The episode explains that traditional user‑centric identity systems are insufficient for autonomous AI agents in healthcare, which need a dedicated agentic identity layer to manage fine‑grained PHI access, audit trails, and delegation across humans and machines. It highlights the regulatory complexity of HIPAA, 42 CFR Part 2, and state privacy laws that make generic solutions like Okta unusable without deep vertical customization. The host outlines what an agentic identity platform would look like, its required authentication and authorization stack, and why market entry will likely flow through EHR vendors and health‑system IT teams. Finally, the discussion quantifies a multi‑billion‑dollar opportunity and advises founders to focus on OAuth scopes, CMS interoperability, and building robust moats.
CMS Broadens Drug Price Negotiations to Part B Therapies
The Centers for Medicare & Medicaid Services announced a third round of drug price negotiations that for the first time includes Part B physician‑administered therapies. By extending the Inflation Reduction Act’s pricing provisions to infused medicines, the move pulls doctors into...
FDA Clearance Sets Stage for U.S. Commercialisation of Eyonis LCS
Median Technologies has named veteran imaging executive Oran Muduroglu as President of its U.S. subsidiary, Median eyonis Inc., to spearhead the commercial launch of eyonis LCS, an AI‑powered lung‑cancer‑screening SaMD that recently received FDA 510(k) clearance. The rollout will leverage a defined Medicare reimbursement...
Oral Nanozyme Treats Colitis-Linked Mental Disorders via Gut-Brain Axis
Researchers at Yangzhou and Nanjing Universities have created an oral polysaccharide‑engineered nanozyme—fucoidan‑cerium nanocomplexes (FucCeNCs)—to treat colitis‑associated anxiety and depression. The nanocomplex combines cerium’s superoxide dismutase‑like activity with fucoidan’s prebiotic properties, enabling simultaneous reactive oxygen/nitrogen species scavenging and gut microbiota modulation....
CRISPR Therapeutics Gains After Earnings as Pipeline Hope Grows
CRISPR Therapeutics shares rose over 12% after reporting Q4 2025 earnings that showed a larger‑than‑expected loss and minimal recognized revenue. The company’s flagship therapy CASGEVY generated $54 million in sales, but under its revenue‑sharing deal with Vertex only $0.86 million was recorded. CRISPR...
Take Two: EP398: Why Are Commercial Carrier Marketplaces Completely Boring? Maybe Because There Isn't a Marketplace, With Jacob Asher, MD
In this episode of the "No Market" series, host Stacey Richter talks with Dr. Jacob Asher, a former chief medical officer for major health plans, about why commercial carrier marketplaces—especially in California—are stagnant and lack true competition. They identify six...
STAT+: What to Expect From Gossamer Bio’s Late-Stage Lung Disease Study
Gossamer Bio is set to announce results from its Phase 3 trial in pulmonary arterial hypertension (PAH) before the end of February. The readout follows a Phase 2 study that delivered modest, sub‑par efficacy, which the company attributes to an...
DHL Expands Airfreight Cold Chain Network
DHL Group is expanding its dedicated air‑freight cold‑chain network, adding more than 30 GDP‑compliant aviation hubs and a new Brussels‑Cincinnati corridor. The rollout is part of a €2 bn investment in DHL Health Logistics and includes a dedicated Boeing 777 freighter painted...
Partial Reprogramming of Neurons Encoding Memory Improves Cognitive Function in Aged Mice
Researchers applied cyclic OSK (Oct4‑Sox2‑Klf4) gene therapy to memory‑encoding neurons in aged mice, achieving partial cellular reprogramming without full pluripotency. The intervention reversed senescence‑related gene expression, restored youthful epigenetic patterns, and normalized synaptic plasticity in both hippocampal and prefrontal engrams....
Anthropic: It’s “Critical” To Bring Company Products to EHR
Anthropic is pushing its Claude AI model into electronic health record (EHR) systems, arguing that integration is essential for real‑time clinical value. The company highlighted a roster of 25 healthcare partners, including Abridge, Novo Nordisk, Genmab and Banner Health, to showcase both...
Pharma Pulse: FDA’s Moderna Reversal and Eli Lilly’s $100 Million IL-6 Bet
The FDA has reversed its earlier refusal-to-file and will review Moderna’s seasonal mRNA influenza vaccine, with a decision slated for August 5, 2026. Moderna now seeks full approval for adults aged 50‑64 and accelerated approval for those 65 and older. Meanwhile, Eli Lilly...
Scotland’s First Photon-Counting CT Scanner Set to Advance Multi-Organ Research and Enhance Patient Diagnosis & Care
The University of Edinburgh has installed Scotland’s first photon‑counting CT scanner, the Siemens Healthineers NAEOTOM Alpha, funded jointly with the British Heart Foundation. This technology captures each X‑ray photon, delivering ultra‑high‑resolution, spectral images that surpass conventional CT capabilities. It will...
Prevention Is Turning a Corner as Public Demand Surges – but NHS Digital Infrastructure Is Still Lagging Behind
Public demand for preventative health in the UK is surging, with NHS App registrations now at 33.6 million – roughly twice the nation’s Netflix subscriber base. A PA Consulting survey shows eight‑in‑ten NHS leaders believe digital tools can cut health inequalities,...
Antioxidant Nanoparticles May Protect Male Fertility During Chemotherapy
A preclinical study published in Reproductive and Developmental Medicine found that combining melatonin with zinc oxide nanoparticles mitigates cyclophosphamide‑induced reproductive toxicity in male rats. The antioxidant duo restored testosterone and luteinizing hormone levels, lowered oxidative stress markers, and preserved spermatogenic...
Nevada Debuts Public Option Amid Tumultuous Federal Changes to Health Care
Nevada launched its Battle Born public option health plans last fall, aiming to lower premiums and expand coverage. Early enrollment reached just over 10,000 members, far short of the 35,000 target set by state officials. The program must cut premiums...
MSD and Mayo Clinic Team up to Advance AI in Drug Development
Merck (MSD) and Mayo Clinic have launched a research partnership that blends Mayo's Platform architecture and multimodal clinical‑genomic data with MSD's virtual‑cell technologies. The collaboration gives MSD direct access to de‑identified imaging, lab, molecular and notes data to train and...
Alira Health Sued for Stock Manipulation and Fraud
Alira Health and its CEO Gabriele Brambilla face multiple lawsuits from startup founders alleging fraud, unjust enrichment, and violations of the Securities Exchange Act. The plaintiffs claim Alira used inflated stock to acquire companies, set unattainable performance targets, and then...
Opinion: My Biggest GLP-1 Ethical Problem: Patients Who Don’t Want to Stop
GLP‑1 agonists have moved from scarcity to abundance, reshaping weight‑management practice. In 2023, shortages forced clinicians to ration these drugs, often off‑label for obesity. Today, the surplus creates a new dilemma: patients seeking extreme, unsustainable weight loss and refusing to...
Verily Launches Self-Serve Access to Pre Platform with New Segmed and RefinedScience Datasets
Alphabet’s Verily has introduced a free, self‑serve Standard tier for its Pre precision‑health platform, allowing researchers to access the Exchange catalog and Workbench environment with just a Google account. The rollout adds three high‑impact datasets: a single‑cell AML cohort from...
Stratasys Introduces Multi-Material 3D Printed Anatomical Model Preset for Dental Training
Stratasys has launched a multi‑material 3D‑printed dental anatomical model preset using its PolyJet technology, enabling realistic, customizable training devices. The preset defines material ratios and distribution patterns to consistently mimic bone, teeth, nerves, and soft tissue. Models can be personalized...
Gold@MnFe‐Prussian Blue Analog Yolk@Shell Nanoparticles for Light‐Triggered and pH‐Sensitive Drug Release
Researchers have engineered Au@MnFe‑Prussian Blue Analog yolk‑shell nanoparticles that combine a hollow cavity with a functional shell for biomedical use. The synthesis creates a ~75 nm interior, achieving roughly 50% loading efficiency for the chemotherapeutic doxorubicin. Partial etching and redeposition of...
Achieving High‐Efficiency Type I Multimodal Photosensitizers via a Synergistic Rigidity‐Flexibility Strategy for Hypoxia‐Resistant Tumor Therapy
Researchers introduced a donor‑acceptor (D‑A) molecular design that couples a rigid coplanar backbone with flexible side chains, dramatically raising near‑infrared molar extinction and fluorescence brightness. The resulting phenothiazine‑based photosensitizer, EL‑TPO2F, also exhibits strong type‑I reactive oxygen species (ROS) production and...
Hana Health by DSS Imagetech Partners with Overture Life to Bring World-First Automated Egg-Freezing Technology to India
Hana Health by DSS Imagetech has signed an exclusive agreement with Overture Life to launch DaVitri, the world’s first automated egg‑freezing platform, in India. The system standardises the vitrification step of IVF, cutting variability and enabling clinics to handle more...
Swedish CubaseBio Emerges From Stealth with €5.9 Million to Scale Volumetric DNA Microscopy
Swedish startup CubaseBio has emerged from stealth after raising €5.9 million in blended financing – a €2 million European Innovation Council grant plus €3.9 million from Voima Ventures, Nordic Science Investments, Illumina Ventures and other life‑science investors. The capital will accelerate development of...
Hampshire Hospitals NHS Foundation Trust Boosts Imaging Productivity and Resilience Following Major CT Upgrade
Hampshire Hospitals NHS Foundation Trust has completed a major CT upgrade, standardising imaging across Basingstoke, Winchester and Andover with a unified fleet of Canon Aquilion ONE/PRISM and Aquilion Prime SP scanners. The project introduced a dedicated cold‑site CT in Basingstoke,...
9 Companies Hiring Now in Pennsylvania
Pennsylvania’s Greater Philadelphia corridor remains a biotech hotbed, housing over 1,200 life‑science firms including AstraZeneca, GSK and Johnson & Johnson. Eli Lilly announced a new injectable weight‑loss manufacturing plant in the Lehigh Valley, projected to create roughly 850 jobs by 2031....
Lancashire and South Cumbria NHS Chooses EBO’s Patient Portal
Lancashire and South Cumbria NHS Foundation Trust is rolling out EBO’s Intelligent Patient Portal (IPP) as part of its digital transformation, offering a conversational AI interface that guides patients through appointment management and care tasks. The portal is built on...
NHS Transformation Directorate Launches Best Practice and Content Guidance for Patient Messaging
The NHS Transformation Directorate has issued best‑practice and content guidance to help NHS staff decide when and how to message patients via NHS Notify, the NHS App, text, email or letters. The guidance combines clinical safety, governance and digital best...
Elsevier ClinicalKey AI Adds NEJM, The Lancet, and HIPAA Compliance
Elsevier has upgraded its ClinicalKey AI platform by adding full‑text access to more than 130 top‑tier medical journals, including NEJM and The Lancet, and by integrating clinical guidelines from leading societies. The new version introduces real‑time traceability, linking AI‑generated answers...
Big Food Pours Millions Into Rebrands as Obesity Drugs Reshape US Demand
US food and beverage giants are accelerating rebranding and product reformulation as GLP‑1 obesity drugs reshape consumer demand. Appetite‑suppressing medications are projected to erase up to $12 billion in snack sales over the next decade, prompting companies like PepsiCo, Coca‑Cola and...
Master Bond Debuts UV26DCMed Dual-Cure Adhesive
Master Bond introduced UV26DCMed, a single‑component, dual‑cure adhesive for medical device assembly that combines UV light for rapid fixturing with a heat bake for full polymerization. The formulation tolerates repeated sterilization methods—including steam autoclave, ethylene oxide, glutaraldehyde, and hydrogen‑peroxide—while meeting...
Scientists Develop the World’s Tiniest Wireless Brain Implant
Scientists at Cornell University have created a wireless brain implant so small it can sit on a grain of salt, yet still record and transmit neural activity. The device uses light‑based optics for power and data, eliminating bulky wires and...
Nib Appoints Soccer Star Mary Fowler As Chief Health & Wellbeing Officer
Nib Group has appointed Australian soccer star Mary Fowler as its chief health and wellbeing officer, underscoring the insurer's push for health literacy, inclusion and female representation. Fowler will leverage her athletic platform to inspire Australians to prioritize wellness and...
Reversing Nerve Cell Age to Combat ALS, Alzheimer’s
Super proud of Dr. Kelly Rich, senior postdoc in our lab who's pioneering nerve cell epigenetic age reversal to treat diseases such as ALS and Alzheimer's 🪨⭐️ https://open.spotify.com/episode/7nWkEH5li36oW9monEIG8B
ElliQ Robot Tackles Loneliness, Featured in NYT
“A robot with soul” ElliQ from @intuitionrobo can help address loneliness & isolation in the @nytimes https://t.co/ydLLNCwnHS
Bone Marrow Cell Atlas Created for Improved Leukemia Research
Researchers at the Princess Máxima Center have produced the first multimodal single‑cell atlas of healthy pediatric bone marrow, profiling nearly 91,000 cells from nine donors aged two to 32. The atlas reveals that children’s marrow differs markedly from adult marrow in...
How Pennant, LiveWell, Grow With A Density-First Mindset
Home‑based care providers are shifting from a broad geographic footprint to an operational‑density model, making clustered agencies the cornerstone of growth. LiveWell Partners emphasizes expanding density within states it already serves, exemplified by its recent acquisition of Empower Home Health...
Cancer Immunotherapy Improved Using Targeted Stress Protein
Researchers at NYU Langone Health identified the integrated stress response protein lipocalin 2 (LCN2) as a key mediator that lets lung and pancreatic tumors evade immune attack. In mouse models, antibodies that block LCN2 restored T‑cell infiltration, slowed tumor growth, and...
Dr. Hope Jacoby, Podiatrist: Leading with Precision in Podiatry
Dr. Hope Jacoby, DPM, has built a leading podiatric practice in Dallas‑Fort Worth, focusing on advanced wound care and foot‑ankle surgery. Her career stems from a sports‑focused upbringing, elite athletic training, and a chief residency that honed surgical leadership. She...
UK Medical Device Testing Hits Record High as MHRA Backs Growth in Brain and AI Technology
The UK Medicines and Healthcare products Regulatory Agency reported a 17% rise in approved clinical investigations for 2025, setting a record high. Average approval times fell to 51 days, outpacing the 60‑day target, while neurotechnology now accounts for roughly a...
Pediatrix Medical Group Inc (MD) Q4 2025 Earnings Call Transcript
Pediatrix Medical Group reported Q4 2025 adjusted EBITDA of $66 million, matching the top of its revised guidance, and delivered full‑year adjusted EBITDA of $276 million. The company projects 2026 adjusted EBITDA between $280 million and $300 million, roughly a 5% increase, while revenue...
Guardant Health Inc (GH) Q4 2025 Earnings Call Transcript
GE HealthCare reported Q4 2025 revenue of $5.7 billion, up 4.8% organically, and posted a record backlog of $21.8 billion with a book‑to‑bill ratio of 1.06. Adjusted EBIT margin slipped to 16.7% after a $100 million tariff hit, while adjusted EPS fell 0.7%...
Travere Therapeutics Inc (TVTX) Q4 2025 Earnings Call Transcript
Vertex Pharmaceuticals reported fourth‑quarter 2025 revenue of $3.2 billion, a 10% year‑over‑year increase, and full‑year revenue of $12 billion, up 9%. The company highlighted strong growth in its cystic fibrosis (CF) franchise, with 7% global expansion and double‑digit gains in the...
Medical Properties Trust Inc (MPT) Q4 2025 Earnings Call Transcript
Medpace Holdings reported a strong Q4 2025, with revenue of $708.5 million—a 32% year‑over‑year increase—and full‑year sales of $2.53 billion, up 20%. EBITDA rose 20% to $160.2 million, though the margin slipped to 22.6% because of higher reimbursable‑cost activity. Net new business awards...
A Transcriptional Program Associated with Neurotransmission in the Living Human Brain
Researchers from the Living Brain Project combined prefrontal cortex biopsies from 130 neurosurgical patients with intracranial recordings of dopamine, serotonin, and other neurotransmitters. Differential‑expression analyses of single‑nucleus and bulk RNA‑seq data revealed reproducible gene‑expression signatures that correlate with fast‑scan cyclic...
Tandem Diabetes Care Inc (TNDM) Q4 2025 Earnings Call Transcript
Tandem Diabetes Care reported record 2020 results, generating roughly $500 million in revenue—a 38% year‑over‑year increase—and shipping more than 90,000 insulin pumps. The company now serves over 200,000 customers worldwide and has expanded its Control‑IQ automated insulin‑delivery algorithm, which has driven...
Select Medical Holdings Corp (SEM) Q4 2025 Earnings Call Transcript
Select Medical disclosed that its Board is evaluating a non‑binding take‑private proposal from the Executive Chairman, adding strategic uncertainty to the near‑term outlook. Fourth‑quarter revenue grew more than 6% year‑over‑year, but adjusted EBITDA dropped 10% to $104.7 million, driven by an...
Insmed Inc (INSM) Q4 2025 Earnings Call Transcript
Insmed reported a $144.6 million net revenue for Brinsupri’s first full U.S. quarter, surpassing internal launch benchmarks. Management set a minimum $1 billion Brinsupri revenue target for 2026 and projected total company revenue to more than double 2025 levels, driven by continued...
Materialise NV (MTLS) Q4 2025 Earnings Call Transcript
Materialise posted a mixed third‑quarter 2025 performance, with overall revenue slipping 3.5% year‑over‑year but the Medical segment hitting a record €33.3 million, up more than 10%. Software and Manufacturing revenues fell 7% and 17% amid macro‑economic headwinds, while operating cash flow...
Madrigal Pharmaceuticals Inc (MDGL) Q4 2025 Earnings Call Transcript
Gilead Sciences reported total product sales of $28.9 billion for 2025, a 1% increase that topped the high end of its guidance. The HIV franchise generated $20.8 billion, up 6% overall and 10% on an underlying basis after removing the Medicare Part D...