Low Leukocyte mtDNA and High Inflammation Predict Elderly
Association of leukocyte mitochondrial DNA copy number and inflammation with mortality among older adults https://t.co/AeqAZIv3er
Blood Factors Drive Aging or Rejuvenation; Therapies Emerging
Aging is increasingly understood as a system-wide process shaped by factors in the blood, which can actively drive either decline or rejuvenation rather than just reflect it. Emerging therapies that modify the circulatory environment show promise in reversing aspects of...
Denied Drug Everolimus Available for $30.88
Wanna know how fucked up this is ? The drug that was denied , Everolimus , can be as low as $30.88 on @costplusdrugs
Insurance Denials Mirror Government Budget Cuts in Care
Unfortunately one of the great lies of US HC. Ask anyone with a serious illness that has been denied care by an insurance company that subcontracted out the denial process to a company owned by overseas private equity firms....
Longevity Pill May Redefine Human‑dog Bonds
YOUR NEXT DOG A new pill could soon extend dogs’ lives. How will that change our relationship with our pets? By @andersen 🔗https://t.co/u2cuBfKGuU https://t.co/Iaw4uoZfZe
Telehealth and Mail‑order Meds Sustain Abortion Access Post‑Roe
Telehealth and abortion medication delivered by mail have been instrumental in helping to preserve access following the Supreme Court’s decision overturning the right to an abortion. https://www.kff.org/womens-health-policy/key-facts-on-abortion-in-the-united-states/
Spice Cabinet May Hold Next Diabetes Treatment
Could a new tool for diabetes treatment be hiding in your spice cabinet? https://t.co/L5RWYeEY9q https://t.co/U4Boj4W4EQ
Zuckerberg Funds $500M AI to Model Human Cells
Mark Zuckerberg backs $500 million push to build AI models of human cells as part of long-term effort to cure disease. https://t.co/nLBDaUVj9Z
Patent Monopolies Fueled Opioid Crisis, Perdue Falls
With Perdue Pharma biting the dust, it might be a good time for a post-mortem that looks at the government-granted patent monopolies that provided the incentive for pushing opioids https://t.co/bWKnxlYaS2
Melatonin Shields Mitochondria From Radiation Damage
Melatonin as a radioprotectant against mitochondrial damage 🤔"Melatonin can protect against irradiation-induced mitochondrial damage, suggesting utility for mitigating the health effects of accidental radiation exposure." https://t.co/XHZYDE916a
Balancing Reform and Regulation in Mental Health Care
Here's a weird tension we don't yet have a clear path to navigate in the mental health system. - Many mental health systems we have in place have been and continue to be oppressive, carceral, and coercive, particularly to marginalized folks. and -...
Malaria Vaccine Team Faced Funding Delays at Every Stage
“The researchers who worked on this malaria vaccine struggled at every step of the process to get faster funding.” ~@salonium
ByteDance's AI-Designed Therapies Spotlight Global Progress
ByteDance’s drug unit presents AI-designed therapies at global conferences Yes this is reality of AI applications, but we are "winning" by slowng Chinese company progress on AI? https://t.co/G3lIeOAddU
Admitting Past Mistake: AMA Not Causing Doctor Shortage
[Deleted a comment alleging that the AMA is the cause of our shortage of doctors. I think this was actually true when I learned it in the early 2000s, but it appears no longer to be true. Mea culpa.]
KRAS G12D Drug Shrinks Tumors, Delays Progression
Setidegrasib, an investigational therapy targeting KRAS G12D, demonstrated tumor shrinkage and delayed disease progression in early trials for advanced lung and pancreatic cancers, offering a potential new approach for hard-to-treat mutations. oncology
Implantation, Not Fertilization, Determines Pregnancy Success
Fertilization is not the hard part. Implantation is where many pregnancies are lost. Anywhere between 30-70% of fertilized eggs never make it to a live birth. Most of those losses happen before a woman even knows she is pregnant. The...
R‑MDDMA Boosts Neuroplasticity and Ant
methylated MDMA analog in animals R-MDDMA "still promoted structural neuroplasticity in cortical neurons, facilitated fear extinction learning, and produced sustained antidepressant-like effects" did not directly activate 5-HT2B receptors https://t.co/w0ltV7VXQL
Boosting NAD+ May Restore Sleep in Dementia
NAD+‒circadian rhythm coupling in dementia "Pharmacological and lifestyle-based strategies targeting NAD+ restoration are outlined as potential approaches to improve sleep and circadian rhythm integrity..." https://t.co/qQXLHS8nou https://t.co/te8QGUftC4
US Spends More on Health, yet Lives Shorter
The USA is the wealthiest country in the world and spends 3-4x more on healthcare than any other high-income country, yet it has a life expectancy that's 3-4 years lower Many people blame the high rates of obesity and a highly...
Affordable GLP‑1 Options Explained by a Doctor
Sooo as a doctor I know, ramai yang nak start GLP-1s. Mounjaro/Wegovy/Ozempic. Ada to lose weight untuk capai healthy BMI, ada yang TTC, to improve diabetes, cholesterol, PCOS, period tak teratur and many more. I also understand cost is a big...
AGEs Trigger SIRT1 Loss, Accelerating Osteoarthritis via RANKL
SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL-Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development "Targeting this mechanism may offer new therapeutic opportunities for delaying age-related OA progression." https://t.co/HB2nmyZ43u
Eldest Daughters Become Doctors, Pre‑trained for Burnout
85 to 90 percent of women physicians are eldest daughters. That is not a coincidence. That is a pipeline. Eldest daughters are trained, before age five, to over-function. They take on a parent's worry. They organize the family. They clean...
Rubber Dams Enable Precision in Modern Dental Care
Why Rubber Dams Matter in Precision Dental Procedures by @IntEngineering #MedTech #HealthTech #Tech #Healthcare #TechForGood https://t.co/5OjCuwDfBy
Chinese Hospital's Blood‑Drawing Robot Hits 94.3% Success
Chinese Hospital Deploys Blood-Drawing #Robot Achieving a 94.3% Success Rate by @Khulood_Almani #Robotics #MachineLearning #ArtificialIntelligence #ML https://t.co/R8YvNL4xEr
Neglected Industries Offer Low‑Barrier, High‑Reward Opportunities
The best opportunities are in the industries everyone has given up on. Healthcare admin. Insurance. Legal services. 30-year-old B2B software. The bar for better is extremely low. The lack of glamour is the competitive advantage.
Cancer Survivors Deserve Care Beyond “Tough It Out”
It is unacceptable to ask women who have endured cancer diagnoses and treatments to just "tough it out". Part of comprehensive cancer care is also helping women to live the life they want after they've survived the cancer.
Modern Meds Are Precise; Older Drugs Are Broad-Spectrum
Modern drugs tend to be very tightly targeted. Older drugs like metformin or Tylenol cut a wider swath.
AI Is Already Analyzing Dental X-Rays—Most Don’t Know
AI is already reading your dental X-rays and you probably have no idea [PODCAST] http://dlvr.it/TSKfbM Podcast #PrimaryCare
Court Blocks Mifepristone, Marking New Wave of Abortion Erasure
They said Roe was the last fight. It wasn’t. The 5th Circuit just blocked mifepristone (the abortion pill) by mail. Nationwide. Today. This is INCREMENTAL ERASURE. One regulation. One court. One quiet ruling on a Friday afternoon. Until there’s nothing left. The war on bodily...
Evidence-Based Medicine Once Labeled Dangerous Innovation by Doctors
Obviously you want "evidence-based medicine", but the term was only coined in 1991. Doctors called it a "dangerous innovation", preferring to rely on their judgement over trials.
WHO Labels Night Shift Work a Probable Carcinogen
“The link between lack of sleep and cancer is now so strong that the World Health Organization has classified any form of nighttime shift work as a probable carcinogen." https://t.co/179qEbvyZe
OTC Hearing Aids Offer Affordable, Game‑changing Solution
More hearing aids? Yes, because lots of folks have mild hearing loss, and OTC solutions are affordable and, honestly, game changing. This time I'm looking at the new Techmi FacePro OTC Hearing Aids in this demo and review: https://t.co/W0GUOshnHY #hearing...
Vaccination Quickly Halts Measles Outbreak After Decline
A play in 4 parts: 1. Measles vax rates drop below 90% 2. Measles outbreak infects 1,000 3. 20,000 measles vaccines given 4. No new cases; outbreak over "Measles vaccinations [were] the most effective single containment tool” https://t.co/rE8lSQ45VF
Employers Can Bridge GLP‑1 Coverage Gaps with Integrated Care
GLP‑1s are changing lives. Coverage realities have not caught up. GLP‑1 Flex Care at @OmadaHealth gives employers a way to pair cash‑pay GLP‑1 access with clinical evaluation, medical oversight, and behavior change on one platform — so support does not disappear...
OracleHealth Backs Standardized Prior Authorizations to Cut Costs
The @OracleHealth team proudly supports efforts to establish a more consistent, standardized approach to prior authorization. With this initiative, we can help reduce complexity, lower administrative costs, and better meet patient needs. https://t.co/XI1SKbNmQU
Questioning High Drug Prices and Transparency of New Tech
Oh okay. Just like TrumpRx, which charges patients more for many common drugs. Let’s see some data on how well this technology works and how transparent it really is.
HDL Inflammatory Markers Predict Mortality in Elderly
High-density lipoprotein-related inflammatory markers and their association with all-cause and cardiovascular mortality in an ageing population: findings from a prospective cohort study based on NHANES data https://t.co/WdNtpIgGpI https://t.co/cM0LeTv7io
Don't Let One Hero Eclipse Other Scientific Pioneers
Beware the lure of the romantic main character. Jim Allison is awesome. But don't forget Tasuku Honjo. https://t.co/C4hUtqv7uW
Allosteric Switch in TB Enzyme Opens New Drug Target
A newly identified allosteric switch in the ICL2 enzyme of Mycobacterium tuberculosis reveals a potential pathway for targeting drug-resistant TB, offering insight into protein regulation unique to the bacterium. structuralbiology
Clean Data Drives Success in Healthcare M&A
1 in 5 healthcare orgs went through M&A between 2015 and 2020. But success depends on more than cost-cutting—it depends on clean, accessible data. See how Harmony Healthcare IT can help: https://t.co/qJlZ72g01S @HarmonyHIT #ViVE2026 #HITSM
CNS Gene Therapies Showcase Tau-Targeted VY170
CNS Gene Therapies Featured in Multiple Presentations at ASGCT 2026, Including Late Breaker on Tau-Targeted VY1706 for Alzheimer’s Disease https://t.co/oQ5MCd5piS https://t.co/8KeWSTJ1q7
TMDX’s OCS Tech Drives Rapid Adoption, Pressures Valuation
$TMDX reports Tuesday after the close This is the only company on earth that keeps a donor heart, lung, or liver beating outside the body Not a metaphor... the organ stays warm and oxygenated e2e The number to watch on Tuesday isn't rev,...
Governor's Promised Hospital Ships Still Missing in Greenland
Hey Governor, have those hospital ships that you promised gotten to Greenland yet? I heard the people there are desperately waiting.
Court Bars Non‑Party Contract
Judge Conway dismissed @veevasystems v. @HeyEpic with prejudice on standing grounds, ruling that non-parties to a contract can't challenge its validity under Wisconsin law. Both the declaratory judgment claim and the tortious interference claim are dead. Conway also...
FDA Approves Early, yet ARVN, PFE Lack Partner
FDA approves vepdegrestrant one month early. $ARVN and $PFE still haven't found (or disclosed) a third-party company to commercialize it. What a world...
Pregnancy Boosts Clot Risk—Move, Hydrate, Watch Symptoms
Your blood becomes more prone to clots during pregnancy. Fibrinogen increases substantially. Multiple coagulation factors rise. Your body starts doing this early in the first trimester itself. The reason is to prevent a hemorrhage. When the placenta detaches, you are...
CDC Reports 7 More Unvaccinated Child Flu Deaths
#Flu season is over but #CDC was alerted last wk to 7 more kids who died from flu. Six were from this past season, bringing the total to date to 155. It will grow becoz these deaths are often reported...
AI Access Gaps Persist: Lower‑SES Americans Less Aware, Use Less
A study of >10,000 Americans documents AI inequalities, lack of awareness and usage among lower SES https://t.co/1s8EMg933Y https://t.co/6BA6p7g2zW
Wall Street Sees BMY Lift, BIIB Rise, REGN Uncertainty
Latest snapshot of Wall Street's take on a trio of earnings reports, from @ByJonGardner and @realJacobBell Bristol Myers’ legacy lift, Biogen’s blue skies and Regeneron’s murky outlook https://t.co/PnGb0o93WL $BIIB $BMY $REGN
2026 Measles Cases Surge to 79% of 2025 Total
#Measles update: In the first 4 months of 2026, there have been 1,814 confirmed measles cases (& doubtless many more that were never confirmed). For context: That's 79% of the total for the entirety of 2025 — but in 4 months,...