Calm Leadership: Diamantas Poised to Benefit Biotech
‘No drama’ Diamantas should serve biotech well as acting FDA chief A nice column from @adamfeuerstein, who apparently ate his Wheaties today. https://t.co/zh5CU9Sv69 via @statnews
RGNX Shows 71% Microdystrophin, Eyes 2027 Approval
$RGNX Duchenne gene therapy study results are out: microdystrophin expression reached an average of 71% of normal across all 31 boys at 12 wks. Functional improvements in a subset of boys followed for one year also seen. The big question...
EIS Officers Claim Bureaucracy Stifles Outbreak Response
This quote in @Craig_A_Spencer's piece in @statnews is most worrisome to me - suggests some of our Epidemic Intelligence Service officers feel like they're being held back from doing their jobs and responding to outbreaks. https://t.co/hAXPZpL1Om
Benadryl Challenge Linked to 100 ER Visits, One Death
Fort Worth children's hospital warns parents about "Benadryl challenge" after 100 ER visits, 1 death 👀"The videos on TikTok claimed that users could get high and hallucinate if they took a dozen or more of the allergy pills..." https://t.co/FFeG1jr40U
Use Lancet PMOS Study to Challenge Providers
For those who want to bring attention to their care providers about PMOS, this is the link to the Lancet PDF: https://www.thelancet.com/action/showPdf?pii=S0140-6736%2826%2900717-8 And this is the main landing page: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00717-8/fulltext These will be important when you challenge your current care provider...
Aspirin Offers Minimal Short‑term CRC Benefit, Definite Risks
Aspirin and other nonsteroidal anti‐inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population ⚠️"Evidence of very low to moderate certainty shows little to no benefit for CRC or CRA incidence in the first 15 years, and...
Advocates Urge FDA to Fast‑Track Ultra‑Rare Treatments
Powerful plea from @TPirovolak41022 to @US_FDA to expedite therapies for ultra-rare diseases #ASGCT2026 #CureSPG50 https://t.co/FTCTgn5TqH
Metformin Shows Potential to Prevent Esophageal Cancer
Metformin Use and Development of Esophageal Squamous Cell Carcinoma "These findings suggest metformin use may have preventive potential against ESCC, which warrants further evaluation," [though this is a case-control study, would benefit from prospective design] https://t.co/w5QmYd9i55
Moderna Tops TIME's 2026 Most Impactful Companies List
This week, @TIME ranked @moderna_tx #1 on its list of the World’s Most Impactful Companies of 2026. To create the ranking, TIME and @StatistaCharts analyzed economic and scientific data to determine which companies most effectively turn resources into value for people...
CMS Freezes New Hospice, Home‑health Medicare Enrollments for Six Months
Wow The Centers for Medicare & Medicaid Services is imposing a six-month nationwide moratorium on new Medicare enrollments for hospices and home health agencies as part of a broader effort to combat fraud, waste and abuse in the Medicare program.
Gene Therapy Virus Implicated in Boy's Tumor, Study Finds
Scientists link boy’s tumor to gene therapy viruses, in rare finding https://t.co/d2jWn0zs9C via @statnews By @Jasonmmast
Japan's Longevity Edge Stems From Lower LTC Mortality
Understanding Japan’s mortality advantage: a comparison of mortality in independent and dependent older adults in Japan and Sweden "Our findings show that Japan’s longevity advantage in old age is primarily driven by lower mortality in the segment of the population utilizing"...
On‑device Optical Sensors Enable Real‑time Decisions in Surgery, Space
New optical sensors can analyze data within the device itself, enabling real-time decision-making in applications like surgery and space exploration while reducing reliance on external computing. innovation
SMS Streamlines Patient Care, Making Healthcare Simpler
The real innovation? Making healthcare simpler for patients. 💡 See how SMS is doing just that 👉 https://t.co/NGjJsvn8FU @DrFirst #SecureSMS #HIMSS26 #HITSM
Marty Makary: The Worst FDA Commissioner in 25 Years
And here's @matthewherper on why Marty Makary was the worst FDA commissioner in 25 years https://t.co/a44yjB5sZn
Lumius Launches Fast, Accessible Universal 3D Body Camera
The future of ultrasound is 3D. Lumius is making it fast, accessible, and intelligent — a universal 3D camera for the body. Congrats on the launch, @treevoo_lumius and @lichenhang1225! https://t.co/7IzDsljqrf https://t.co/7FdahhZ9UK
Gas Tax Pause Signals Washington’s Plan for Entitlement Crises
Pausing the gas tax may be a clue about how Washington will handle Social Security and Medicare insolvencies: https://t.co/KvU9qT3MEC #socialsecurity #gastax #taxtwitter #medicare #aging
LSD Triggers Region‑Specific White Matter Plastic
Curious. Opposite DTI/FA findings to those we recently published on. Region specific? Neuroplastic white matter changes in patients with major depression following lysergic acid diethylamide treatment: Cell Reports Medicine https://t.co/sIXRAZumie
Platforms Turn Data Silos Into Data‑Driven Care
From data silos to data-driven care—healthcare is transforming fast. See how platforms are enabling the shift: https://t.co/SvmHtOF5OR @MEDITECH #HCA #HITSM
16‑Hour Fast Enhances Cancer Immunotherapy via Metabolic Shift
A 16-hour fasting regimen may boost cancer immunotherapy. Transient nutrient stress reshapes tumor metabolism, increasing isoleucine in the TME and enhancing CD8+ T cell function. In mice & patients, short-term fasting improved immune response—offering a feasible way to strengthen treatment. #Fasting,...
Makary Exits FDA; Diamantas Assumes Top Food Role
Makary departs FDA amid turmoil as Diamantas, agency’s top food official, steps in https://t.co/JacvIrgWAe via @statnews
Chinese Hospital's Blood‑Drawing Robot Hits 94.3% Success
Chinese Hospital Deploys Blood-Drawing #Robot Achieving a 94.3% Success Rate by @Khulood_Almani #Robotics #MachineLearning #ArtificialIntelligence #ML https://t.co/BNH5r1f8Pn
XBI Sees Modest Boost After Anticlimactic FDA Decision
$XBI getting small lift (so far) from the Un-Martying of the FDA. It's all very anticlimactic. https://t.co/q4ta0bkJh4
Midlife Vitamin D Linked to Reduced Tau Build‑up
Higher vitamin D levels in middle age are associated with less accumulation of tau, one of the pathological hallmarks of Alzheimer's disease. The strongest protection showed up among those with vitamin D levels at the higher end of the cohort (around...
Metformin May Lower Glucose via Gut, Not Liver
New paper on a proposed mechanism for how metformin lowers glucose, in Nature Metabolism. For such a widely used drug, the picture has been surprisingly murky. We've thought metformin works in the liver by enhancing glucose metabolism/utilization. But biodistribution and new...
Big Tech Accelerates Into Healthcare with Partnerships
Big tech companies like Amazon, Google/Alphabet, Apple, NVIDIA and Microsoft are taking their move into healthcare and medicine seriously. They are developing new, health-related features on their platforms. They are also teaming up with research institutions and developers to create new...
From “Undruggable” To Hope: KRAS Breakthrough
When “undruggable” meets “indefatigable” — the long, “impossible” journey from academia to industry that led to the discovery of KRAS and a potential breakthrough for pancreatic cancer patients. https://t.co/Fj85ry9thu
Evening Workouts Enhance Diabetes Control, Reduce Inflammation
Timing matters 🕒 For type 2 diabetes, afternoon/evening exercise boosts insulin sensitivity & glycemic control, while morning workouts may raise blood sugar. Later workouts are also linked to lower cortisol, less inflammation & better oxidative capacity. #Diabetes #ExerciseScience @WuTsaiAlliance https://t.co/5Bc0PUAE9O
7 Years, 700 Mg/dL Cholesterol, Zero Coronary Plaque
🚨New Paper: "Seven Years of 700 Cholesterol Without Coronary Atherosclerosis" After 7 years of ~700 mg/dl cholesterol, 0 mm3 total plaque (soft +calcified) after expert analysis and AI-guided quantification. Open-access paper linked below.
SANA Adds CD8‑targeted Fusosome SG227 to Pipeline
🚨! $SANA has just reported - in its Q1 ER, that it plans to expand its pipeline by advancing a new preclinical program - SG227. SG227 is a CD8-targeted fusosome that by delivering a genetic material to make BCMA-directed CAR...
RIGL to Sell Approved Veppanu for ARVN, PFE
$RIGL will sell the newly approved Veppanu for $ARVN and $PFE. Modest financial terms https://t.co/9RsbSMzxBf
Expensive AI Therapy Robot Might End Up Dishwasher
What if @DrPatrick builds an expensive AI robot to make NK cell therapies and then those therapies don’t work? I guess the robot could be reprogrammed to wash his dishes.
E‑Patients Redefine Healthcare’s Future at Budapest Symposium
The Future of Healthcare From an E-patient Perspective - Presentation by Dave deBronkart (USA)! The presentation took place in the first scientific symposium about medical futures studies at the Hungarian Academy of Sciences in Budapest, Hungary on the 10th of April,...
Tomatidine Boosts Memory and Cuts Cellular Aging in Mice
Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice https://t.co/jVfshXgzxQ https://t.co/6l86CBdoBC
China Blocks Taiwan From WHO, Taiwan Still Attends
Reuters: China said on Monday it would not allow Taiwan to take part in the annual assembly of the World Health Organisation, which starts next week, as Taiwan said it would send a delegation anyway for meetings outside the actual...
Rehab Must Evolve Into Strength‑Building Training, Not Old Circuits
Rehab in 2026 should look like training. Most still looks like a TheraBand circuit that's been around since Albert Einstein felt a pull in his groin. Real rehab leaves you stronger than the injury did. Demand it.
GLP‑1 Disruption Drives Healthcare to 13‑year Low
GLP-1 disruption has caused the concentrated Med-Tech ETF $IHI to weigh sharply on Healthcare's performance this yr, resulting in what used to be the 2nd largest sector in SPX slipping to just 8% @IBDinvestors @marketsurge Selectivity crucial until this Sub-industry...
DOSE Trial Reveals Best Heart Failure Infusion Strategy
Bolus or drip? What the DOSE trial actually showed about heart failure [PODCAST] http://dlvr.it/TSV5l4 Podcast #Cardiology
Dementia Rates Fell 20% in 40 Years, Saving Trillions
In 1984, around 30% of Americans were diagnosed with dementia by the end of their 80s. Today it’s 10%. If rates had stayed steady there would be 17 million Americans with dementia today. Instead there are 6 million. This saves...
COVID Spread Can Occur without Close, Prolonged Contact
Really good from @PaulSaxMD “In this outbreak in particular, we are still learning about how transmission occurred. Some infected individuals reportedly did not have prolonged close contact, suggesting that simple assumptions about risk may not fully explain what happened aboard...
Outbreaks Prove Strain Doesn't Need Close Contact
Why is everyone ignoring evidence from outbreaks of this specific strain that are *very* clear that it doesn’t require prolonged close contact?
California's Job Growth Driven by Dubious Healthcare Fraud
Not only is all of California's job growth all healthcare, probably 50% of it is state funded fake "home health aide" makework fraud. https://t.co/uthV10Cbzd
New AI Target Discovery Paper Sets Benchmark
New Paper Alert 🚨: A collaboration with the leading target ID experts in Nature Reviews Drug Discovery. If you are looking to teach your AI target discovery - this is a good place to start. Thanks Peter Kirkpatrick for giving...
Yutrepia Delivers Dramatic Cough Relief and Titration Benefits
“… when we go back to them and they begin prescribing Yutrepia, they come back with their own anecdote around that they're seeing a night and day difference, particularly around the cough and the ability to titrate and drive outcomes.” -...
Trump Cut CDC Cruise Inspection Unit, Risking Outbreaks
Remember when I warned about this last year? The Trump admin gutted the CDC unit that inspects cruise ships for outbreaks…the one that’s supposed to catch these things before they become international emergencies. The inspectors who got laid off? Their jobs were...
Supreme Court Allows Abortion Pill Access for Three Days
JUST IN: The Supreme Court grants a widely accessed abortion pill temporary availability for at least three days.
UnitedHealth Ends Spread Pricing, Signals PBM Reform
Optum Rx/UnitedHealth says its ending "spread pricing" in its PBM, after years of criticism, @ShelbyJLiv reports for @endpts This is a big change in PBM policy, as PBMs face pressure to reform some of the practices they've faced scrutiny over: https://t.co/jq4FmvrO9C
HHS Leader Undermines Science, Stifles Agency Function
At a time when there's so much criticism around leads of FDA, NIH, etc, need to be clear what the core issue is: head of HHS who is effectively inimical to science. It's a preposterous situation. While it holds, essentially...
PRME's Real Money Comes From Non‑Therapy Services
Day 23 of 30: How $PRME Prime Medicine actually makes money Most people think it's a gene therapy company It's not yet... it has zero approved drugs and almost zero recurring revenue Here's what's actually paying the bills 🧵
Make Pap Smears Tolerable: Small Speculum, Warm, Lidocaine
Quick thing on painful Pap smears: I had vulvodynia and vaginismus for years, which made getting a pap torture. The following helped me: 1) plastic speculum in the smallest size, 2) warmed or temperature neutral, 3) lidocaine. Some places will...