It can take decades for new medical research to change what happens in the exam room. AI is going to massively accelerate this process. The dissemination of medical research into clinical practice is not slow because the science is slow. It is slow because it takes years for important original research to become part of clinical guidelines, but then, more importantly, it takes a very long time for providers to pick up and incorporate those guidelines into their practice. We have systems like conferences and CME, which help providers learn about the latest guidelines and incorporate them into their practice. But because it is mostly voluntary, and especially if you are not in an academic center, the implementation of the guidelines ends up being heterogeneous and unevenly distributed. You can imagine that some doctors might not change their practice to represent the latest guidelines for years. I have seen this firsthand, where a patient comes into the clinic or the hospital and is not on guideline-directed medical therapy. Academic centers try to move folks onto GDMT when they have a touchpoint, as long as there is not a good reason not to. As clinicians use AI as a collaborator when creating treatment plans and documentation, they are going to be using AI that has much higher than human awareness of the latest guidelines. This means that clinical guidance is going to reach patients not because their doctor went to a conference or did CME, but because the AI tool their doctor is using had access to that information. The dissemination of guidelines is going to get much better because of AI.

The unfounded move by @HHSGov against mRNA vaccines will hurt our future potent immune therapy vs cancer. Another point of progress for triple-negative breast cancer with individualized neoantigen mRNA vaccines today @Nature Adds to successful pancreatic, renal cell, melanoma reports...

We could prevent diseases so much better but we haven't learned to listen to when biology whispers long (10 + years) in advance. A key theme in Super Agers, too. https://t.co/0pSap3f32N @NathanPriceSci @ @nrappapo @BuckInstitute example below for Type 2...

Another good use case for agentic AI in medicine: diagnosis of rare diseases. Exemplified by DeepRare https://t.co/XBd68V3iDl https://t.co/rBl5yn95sI
The FDA’s Moderna $MRNA pirouette is one more sign of chaos at the agency https://t.co/zThJqhT2BS via @matthewherper
A “Variant of Unknown Significance” is a genetic finding that can’t yet be interpreted, leaving families with uncertainty instead of answers. Now, AI agents can help connect sequencing data with scientific literature and biological context to turn VUS into traceable, evidence-backed...
AI medical advice: Not ready for prime time. A study by the Icahn School of Medicine at Mount Sinai, published in The Lancet Digital Health, reveals vulnerabilities in medical AI systems. https://t.co/ArD323yhzL #research #AI #healthcare #medicine
This is the kind of AI that moves me. After 18 years of silence, Ann spoke again. A brain implant reads signals from her speech cortex. AI decodes them in real time. A digital avatar restores her voice and facial expressions. What’s new? Not text on...

Resveratrol protects kidneys from fat accumulation and diabetic kidney disease by activating SIRT1, similar to its effects on fatty liver 🐁 www.sciencedirect.com/science/article/abs/pii/S1098882326000067
RFK Jr. has long criticized pharma's influence on the federal government. But Dr. Oz, talking to PhRMA today, took a different approach: welcoming the idea of closed-door meetings and urging industry leaders to work in the administration. w/ @LizzyLaw_ https://t.co/xZUFKVKRdJ

This is a big deal. Since 1958, the FDA has allowed food companies to self-certify ingredients as "Generally Recognized As Safe" (GRAS). In comparison Europe only allows ~400 such additives to their foods. In the US there are 4,000–10,000 ingredients that are added...
You can just take a picture of your medical data or upload the file to get a second opinion from Grok

With all the attention on China for TOPO-I ADCs of late, how about the potential for European agents, especially ones involving novel targets? Our latest expert interview drops with some hard hitting and candid opinions from a battle hardened...
The next decade is the brain health decade, as I discussed with Bristol Myers Squibb (@bmsnews) CEO Chris Boerner at their Global Town Hall last week when @Thrive Global launched our brain health partnership to their 34,000 employees. BMS is...

What if a physician could inject you with a plasmid that would induce an immune response against a protein needed for cancer cell survival? This novel strategy is being tested and looks promising for refractory cancers. Talking Biotech 488 ...

"Immune Reset" Rebooting the immune system by depletion of B cells, like a reboot of a computer, to achieve cures vs autoimmune diseases https://t.co/253NtyFmCN

p-tau217 is a breakthrough blood test for risk of developing Alzheimer's disease. Important to know there are sex differences for this biomarker, with women having higher values at baseline and more tau deposition. @JAMANeuro https://t.co/Xrr8SjsiVY https://t.co/eyDt6mgSqR

A psychedelic quickly reduced depression (in patients with major depression disorder) in a small, double-blind placebo randomized trial @NatureMedicine https://t.co/vvug72VGBi https://t.co/Tn58rP0ufS

A new Science #Robotics study describes a #bionic eye that can simulate irregular pupils such as a cat’s vertical pupil for precise focus while hunting and a toad's heart-shaped pupil for improved depth perception. https://t.co/p1uZy6rbky https://t.co/X4pzdrnoIi

When the LLM rewrites the radiology report, patient understanding is increased and clinical accuracy is maintained. @LancetDigitalH @curtlanglotz @smrabd https://t.co/q2UHebBQG7 https://t.co/IwZAx59brY

Precision treatment with artificial intelligence assisted subtyping enhances therapeutic efficacy in HR+/HER2− breast cancer: The LINUXtrial https://t.co/UF4Lt3g5QK https://t.co/LWuJYD2qGh
5 Hidden Themes Driving China’s Biotech Surge | Ep. 314 ...and 5 Bold Predictions for What’s Next https://t.co/TxBhvw5PG8 https://t.co/jTR63o431j

Think AI will reduce demand for doctors? Consider this: Claude writes 100% of its own code, yet Anthropic's engineering team is exploding. We aren't looking at the end of the physicians, but the birth of Medical Orchestrators. When asked why Anthropic...

This is how I test 120 biomarkers for $99 and get CT calcium scans anywhere nationwide. Vitals Vault. https://www.vitalsvault.com/
Regarding this, there was a couple questions on does the pacemaker continue to advertise - most BLE implantable devices go into a sleep type mode. In this case, we are lucky - it does not. We know based on law enforcement...

Two things that may help restore cartilage —15-PDGH inhibition https://t.co/chCj9Lj5qk —Semaglutide (Ozempic), independent of weight loss https://t.co/fqbrQQYfRt https://t.co/6CRdY1QtC1
When a celebrity tragically dies with massive medical debt, I’m left with the questions. Did they have insurance? People with insurance absolutely have medical debt, but out-of-pocket costs are capped. Debt may be from out-of-network care, claims denials, or unocvered...
This is not a Saudi-USA Biotech Alliance, it’s a Saudi @DrPatrick $IBRX “you pay we pay” marketing campaign. Anktiva is stalled in the US because he can’t generate the clinical data to move the drug forward, so he goes to...

Printing brain phantoms in a support gel and selectively replicates gray and white matter https://t.co/9rIVOPCjd2 https://t.co/LFwa9Qlqjc

Those “direct-to-physician” CDS AI tools like OpenEvidence and DoximityGPT? They're now going after health systems too. My 5 thoughts on how this will all play out: First, the gist of what was announced: → Sutter Health will integrate OpenEvidence with Epic, allowing...
We should have a class of drugs you can only sell to people over 70 —super aggro longevity stuff, muscle regeneration, etc - tolerate more possible bad side effects given you don’t have much time left for effects to manifest...
But this is such treachery. Doesn’t our govt understand pandemic threats? New waves of zoonotic flu, SARS-3 coronavirus; arboviruses from climate change; bioweapons from our enemies: Russia, DPRK, Iran; return of measles, pertussis, soon polio. What’s going on? Exclusive: Key US...

1. Time for a #flu & #measles update. Six more kids have died from flu, bringing the year-to-date total to 66. Sadly there will be more deaths reported but hopefully this year doesn't approach last year's dreadful pediatric death toll. #CDC...
This was over two months ago at ASH, so ages, but here's how Disc's CEO said the bitopertin review was going back then. $IRON https://t.co/9SvSML6th8
FDA rejects rare disease therapy from $IRON Disc Medicine, early recipient of commissioner’s voucher CNPV program falters out of the starting gate... https://t.co/w4ptB2ecRS via @LizzyLaw_ and me

#NIH to deprioritize pandemic preparedness and biodefense research, @nature.com reports, saying director Jay Bhattacharya wants to focus on known diseases, not possible future threats. What could possibly go wrong? https://t.co/6TpLr6pY3B https://t.co/7rVzvkOzkT

A healthy diet, accounting for longevity-related genes, associated with 2-3 more years of life expectancy from >100,000 people followed 10.6 years, max benefit for starting at youngest age (Figure) @uk_biobank @ScienceAdvances https://t.co/Ji7Wlhj9ZA https://t.co/B6UxuE97xG
Merkel cell carcinoma log, day #566. Completed my 6th PET scan at Dana-Farber yesterday. The radar, such as it is, doesn’t reflect any Merkel cell carcinoma. Lymph nodes look clean. The more I do PET scans, though, the more I...
Earnings roundup: Neurocrine slumps, Alnylam battles skeptics and Ascendis eyes a competitor https://t.co/kU1ex80A24 by @realJacobBell $NBIX - 10% $ALNY - 4% $ASND - 2% $BBIO #biotech
For my book Allergic, I went to Cincinnati Children's Hospital and talked to asthma experts that vehemently argued otherwise...with decades of data behind them. Young (and old) lungs especially need the cleanest air we can manage. This is one of the...

#TEFCA, America’s National Interoperability Network, Reaches Nearly 500 Million Health Records Exchanged as @HHSGov + @HHS_TechPolicy Leverages #Technology and #AI to Lower Costs and Reduce Burden #ASTP2026 https://t.co/0iBnnjnNR3 https://t.co/oFI2brZmfq
“Yes, the rest of the world can maintain a market for vaccines. But will it be as innovative and as vibrant as it has been? That’s a different question.” https://t.co/jB38FWfglo
It would be highly instructive to read the pembrolizumab paper highlighted by @DrPatrick. Of course, he doesn't expect anyone to do that. This is what it says IN THE FIRST PARAGRAPH: The FDA approved pembrolizumab on May 23, 2017, for...