
Four‑Month MDF Cuts NAFLD Liver Fat by 24%
"The 4-month intervention with this MDF was effective in reducing IHTC in patients with NAFLD by an absolute reduction of −5.89% and a relative reduction of −24.30% after adjusting for weight loss. Such effect was partly mediated by altered composition and metabolic profile of gut microbiota."

Tech Revolution Will Redefine Some Medical Specialties More Than Others
Every medical specialty will transform differently due to the technological revolution. In certain fields, such as nursing, psychiatry, obstetrics and gynecology, innovation will have much less impact than on dentistry, cardiology or pathology. In this e-book, we specify in detail how...

Gene Therapy Poised to Redefine Obesity Treatment Landscape
1/GLP-1 obesity and weight-loss drugs - such as $NVO Ozempic & Wegovy and $LLY Zepbound & Mounjaro have long become a household name - making Obesity the fastest growing market in the BioTech and Pharma ecosystem and generating unprecedented revenues....
AI Halves MRI Scan Time with Synthetic Image Interpolation
A new AI software that essentially fills in the blanks between image slices with synthetic images, enables 2x MRI acceleration ! 👇 “Scans of the abdomen that previously took around 23 minutes now are finished within just nine minutes.” 👏...
Microdosing Lacks Scientific Validity and Therapeutic Effect
What does 'microdosing' even mean in this context? It is likely to have no therapeutic effect at all. You might as well just drop it in the ocean. This is not a scientific valid strategy.

Humanity and Excellence Thrive Together in Supportive Healthcare Cultures
If you work in medicine, you know the feeling of being asked to deliver more while the system quietly strips away the humanity required to do the job well. That is what makes this episode of The Podcast by KevinMD worth...

Ultra-Endurance Running May Speed Up Aging, RBC Damage
Ultra-Endurance Running May Accelerate Aging and Breakdown of Red Blood Cells | @ASH_hematology https://t.co/aYbsblfTwZ https://t.co/NYSKw0843c

Bootstrapped Cryo‑AI: LLMs Power Life‑Saving Freeze Tech
Meet Dr. Mark Woodward, undergrad and grad from Stanford, PhD from Harvard, Many years at Google as part of Google brain. One day he realizes that we need the enabling technology to pause biological time for patients that are about...

AI Turns Patients Into Self‑Diagnosing Symptom Spirals
The ChatGPT Symptom Spiral: when ChatGPT tries to convince you that something is wrong with your medical record or lab results. We have to get used to dealing with patients getting into such troubles, because patients have always tried to...
OHGR Lands 3‑year Sheffield Deal; Valuation Dips, Modest Dividend
#OHGR got Sheffield Teaching Hospital to sign up to 3 year deal. ShareScope has fwd p/e 19 falling to 18 and fwd Divvy 2.6% each of next 2 years. Interesting with NHS a national disgrace. I don't hold.
Weight Rebound Is Inevitable After Stopping GLP‑1s
Why weight regain is a predictable biological response after stopping GLP-1s [PODCAST] http://dlvr.it/TRvfHv Podcast #Diabetes

Lower Cholesterol Linked to Reduced Dementia Risk
Does lowering cholesterol harm the brain? A large genetic study suggests lifelong reductions in atherogenic lipoproteins are associated with lower—not higher—dementia risk. https://t.co/QutNZzb4PH https://t.co/T84ZLIKq4A
Empowering Women to Defy Healthcare Inequities
Someone asked me recently what drives me. It’s an easy answer. I’ve spent my career watching women be undertreated, underinformed, and underestimated by a healthcare system that has repeatedly failed them. So here’s my mission: I help women defy the conditions that threaten...
Gender‑affirming Care Is a Medical, Not Civil‑rights Issue
My view on the issue of gender-affirming care has always been that it should be treated as a MEDICAL issue, rather than as a civil rights issue. Activists can conflate the two for a long time, but not forever.
Humanoid Robots Set to Transform Hospitals and Homes
Humanoid #Robots Designed to Enhance Daily Life in Hospitals and Homes via @ZappyZappy7 #EmergingTech #Technology #Innovation #TechForGood https://t.co/Mbb3aFNNLo

Addressing Climate Health, Vaccines, and Antivaccine Threats at Darwin Day
I look forward to giving talks and lectures this coming weekend @uiowa for their Darwin Day celebrations, speaking on climate health, global vaccines, and the dangers of rising antivaccine activism https://t.co/qjv3pnN3oB https://t.co/ISy1vMm9hG
AI Meets Drug Discovery at NYC Meetup Tuesday
AI x Drug Discovery meetup next Tues (14) in NYC ! @ginkgo excited to host with @AAlphaBio — sign up here : https://t.co/GG5c7F4ogO
Try Loading, Not Surgery, for Degenerative Joint Tears
Fake surgery is just as good as actual surgery. For these conditions. Degenerative Rotator Cuff Tear Degenerative Meniscal Tears Subacromial Decompression for Shoulder Pain Whenever surgery is recommended make sure to FIRST ask what happens if you load it instead.
3D‑Printed Spanlastics Directly Target Tumors, Cut Side Effects
3D-printed spanlastics, microscopic carriers for cancer drugs, show potential to target tumors directly and reduce side effects by concentrating therapy at the tumor site rather than throughout the body. nanotechnology

Trump Policy Blocks Foreign Doctors, Deepening U.S. Shortage
Shameful and moronic: "Trump’s Immigration Policy Sidelines Foreign Doctors Amid Shortage: Physicians from 39 countries are being pushed out of U.S. hospitals as a policy blocks their ability to work." https://t.co/H5bNHlIhrz https://t.co/b1jQU4oIDU

WHO Labels Night Shift Work a Probable Carcinogen
“The link between lack of sleep and cancer is now so strong that the World Health Organization has classified any form of nighttime shift work as a probable carcinogen." https://t.co/179qEbvyZe

State Policies Split American Longevity Across Geography
Policy polarization is rewriting the American geography of longevity "...because where you live is increasingly tied to how you live, as state policy contexts within the country pull father apart, so too do the patterns of American longevity..." https://t.co/vofUi8dN3S https://t.co/c68k3lJ7gb

One Psychedelic Dose Quickly Eases Depression, Trial Shows
Single dose of a psychedelic drug can rapidly reduce depressive symptoms, clinical trial suggests https://t.co/c72qpfwQPm https://t.co/xR7hbj4v8e
Repurposing Approved Drugs: Small Trials Explore New Uses
Great reporting from @Philanthropy on our grantee @CuresWReach, which runs small trials testing whether existing, approved drugs might work for entirely different diseases.
Anti‑vaccine Activism Cost 200‑300k Lives, Says Author
Yes, among people who refused Covid vaccines during the delta and BA.1 omicron waves in 2021-22, that resulted in 200,000-300,000 needless deaths. They were victims of antivaccine activism driven by politics and the corrupt wellness/influencer industry pushing ivermectin, which did...
Teen Amenorrhea Needs Energy Assessment, Not Immediate Birth Control
When I lost my period at 14, the first thing my doctor did was put me on birth control. No questions about what I was eating. No questions about how much I was exercising. No investigation into why a 14-year-old...

2027 Rate Notice Beats Forecast, Boosts Medicare Advantage
1/ The Final 2027 Rate Notice will be welcome news for those battered Medicare advantage stocks The Final notice comes in at 239bps better than the Advance notice (when asked recently, I hazarded it would be 150-200bps better) let's revisit this string...
Automating Chart Retrieval Transforms Record Requests Into Workflow
Manual record requests still drain time from practices. David Cohen explains how Greenway Health is working with Moxie to automate provider-to-payer data transparency — turning chart retrieval from a task into a workflow. 🔗https://t.co/Nb90e3GrsC @greenway #EHRstrategy #HITSM https://t.co/c3HJsXikz6
Swallowable Robot Camera Redefines Future Endoscopy
PillBot: The Swallowable #Robot Camera Transforming the Future of Endoscopy by @pascal_bornet #HealthTech #Tech #Technology #EmergingTech #TechForGood https://t.co/FnSO96W0A0
Study Shows Subcutaneous Tepezza Matches Infused Version
Under-the-skin Tepezza comparable to infused version in key study, Amgen says https://t.co/rOQqbRmEpL $AMGN $VRDN - 25%
White House Budget Officially Ends COVID Mask Mandates on Flights
White House Budget Bans COVID Air Travel Mask Mandates — Four Years After They Already Ended - View from the Wing https://t.co/UMKew7Rr5W

Vegetarian and Vegan Diets Linked to Higher Hip Fracture Risk
Could a plant-based diet make your bones weaker? In this meta-analysis that looked at 529,672 participants (average ages of 46–63; 57% women, 43% men), both vegetarian diets and vegan diets were associated with a HIGHER risk of hip fracture: https://t.co/3u18PxPmrk...
Bad Peptide Manufacturing, Not the Peptides, Drives Danger
Just because peptides are manufactured badly and contain toxins does not mean that they will be safe and effective if manufactured well. Seriously, just eat whole foods, exercise, and maybe take a damn statin.

Diabetes Drug Replicates Exercise Effects in Prostate Cancer Patients
How a Diabetes Drug May Echo the Benefits of Exercise in Prostate Cancer Care “From a clinical standpoint, seeing a metabolic signal that mirrors what we associate with intense exercise was striking… For patients whose treatments or symptoms limit physical activity,...
AI Will Serve as First-Line Support, Not Replace Therapists
Simply put, #AI won't replace therapists, but it will absolutely become the first line of support for many people who otherwise would have no access to care—so governance and guardrails matter more than ever. #health #healthcare https://t.co/aCaFxLV5kI

Meta-Analyses Reveal Psychedelics Boost Brain Circuits
Two systematic, meta-analyses on psychedelic drugs today Brain Circuit Function @NatureMedicine https://t.co/nBmjreYEXU Depression @NatMentHealth https://t.co/zJR06AsC0Z https://t.co/qpWdjzBR4D

Cell Senescence Drives Cancer Risk, Yet Can Be Modulated
Cell senescence and how it predisposes to cancer, no less how we may be able to modulate it. An outstanding @CellCellPress review https://t.co/bmAXOS1Ybz

Vitamin D3 Preserves Telomeres, Slowing Cellular Aging
As a medical school professor, I have watched vitamin D research for decades. This trial finally delivers causal evidence. The VITAL randomized controlled trial -- the gold standard -- followed nearly 1,000 adults aged 50+ for 4 years and found that...
AI Turns Specialists Into Scalable Generalist‑Specialists in Healthcare
In @Health_Affairs Scholar, @bobkocher, Siobhan Nolan Mangini (both of @Venrock) and I argue that – by scaling specialist-level knowledge – AI will create, in essence, the "generalist-specialist." We explore the far-reaching implications for healthcare. https://t.co/FozKzBoINd
Trump Proposes Cutting Medicare, Medicaid to Fund Wars
Trump says he wants to cut Medicare and Medicaid to pay for his fun little wars https://t.co/V1EQfyPLmS
Eli Lilly's Oral GLP‑1 Faces Price War Threat
6April: Why are @EliLillyandCo investors concerned that sales of its just-approved oral GLP-1 may be dampened this year by a price war with @novonordisk? Read about $LLY & $NOVOB plus updates on $INO $ORIC & $SGMO in my latest StockWatch for @GENbio: https://t.co/leir6iyURg
ACSM Releases Definitive Guidance on Resistance Training
American College of Sports Medicine Position Stand on Resistance Training is here. #exercise #health #MedTwitter #CardioTwitter #lifestylemedicine #pavingwellness https://t.co/11XunfB41e
UnitedHealth's $3 B AI Bet Promises Patient Benefits
UnitedHealth Group + AI +Polk winner @caseymross = A must read. $UNH is making a $3 billion bet on AI. What does it mean for patients? https://t.co/irkyZi8Wj6
Myeloma Survival Breakthrough: Two Decades After Dalton’s Wish
I remember interviewing Bill Dalton in 2005 about new developments in myeloma and how he wished for new regimens to take OS out beyond 3-4 yrs. Two decades on we've hit jackpot...
Complex Careers May Cut Dementia Risk More Than Education
Getting an education is important for a lot of reasons, but there might be one reason you haven’t heard — it could lower your risk of dementia later in life. Decades of research have supported this claim, with one study...
AI Can't Replace Human Empathy in Healthcare
The big issue here surely is the lack of true empathy and therapeutic relationship. Care is not just diagnosis and treatment-it involves emotional support, motivation, and reassurance that AI cannot fully replicate. #AI #health #healthcare #aichatbot https://t.co/ImuiD51Vna
FDA Backs Permanent Re‑authorization of Pediatric PRV Program
FDA calls to permanently re-authorize the rare pediatric disease PRV program in Friday's 2027 budget plan -- far cry from the FDA that complained to the GAO about PRVs as distracting from their public health priorities https://t.co/i79F7X1ECw
FDA Delay Shuts Down Small Biotech in Four Months
How a four-month FDA delay forced a small biotech company to close its doors https://t.co/6vMGJM5SjH

Optimal Sleep for Insulin Resistance: 7 Hours 18 Minutes
As a medical school professor, I teach that sleep matters for metabolism. But now we have the precise number. A study of 23,475 adults published in BMJ Open Diabetes Research & Care found the optimal sleep duration for preventing insulin resistance:...

Aging Gut Loses Magnesium, Boosting Inflammation Risk
As a medical school professor, I never imagined a single mineral could be this important to gut health. But the data is staggering. A new study in Aging Cell found that magnesium levels decline specifically in the gut as we age...