B‑cell Reboot Shows Promise Across Multiple Autoimmune Diseases
More success for rebooting B cells towards cure of different autoimmune diseases beyond lupus, MS and others https://t.co/sFGMiFeiEF https://t.co/Dbvca9eox8
Beyond T(11;14): Expanding Venetoclax Use in Myeloma
Venetoclax in myeloma: t(11;14) and what else? {Commentary} [Apr 2, 2026] Catherine Pellat-Deceunynck @BloodPortfolio https://t.co/Zar26htoUT #mmsm #PrecisionMedicine https://t.co/zm0Fv6GY2l
Trump’s Anti‑insurer Rhetoric Masks Policies Boosting Profits
The Trump administration has voiced some tough rhetoric about health insurers. But almost every major decision from Trump officials has benefited insurers and their bottom lines. The new Medicare Advantage rule is the latest example. https://t.co/ziGzSwknqK https://t.co/N3ACGahj3C
GSK’s Leucovorin
what a timeline - Sept. 1999 - $GSK withdraws Wellcovorin (leucovorin) bc it's not selling Sept. 2025 - GSK is told by FDA to apply for a new indication for leucovorin after an FDA review of lit. March 2026 - FDA approves...
Mixed Metastatic Sites Confound Apparent Treatment Effects
Your clinical trial baseline is a mix of liver mets, lung mets, bone mets, and primary tumors. You compare it to post-treatment samples from different sites. The "treatment effects" you find will mostly be tissue site differences. https://t.co/0PyjMM2Znl
Just 15 Minutes Weekly Slashes Dementia and Diabetes Risk
As a medical school professor, I tell my students: intensity matters more than duration. A massive 7-year study of 96,000 adults just proved it. Published in the European Heart Journal, the findings are striking: People who did just 15-20 minutes of vigorous activity...
Next-Gen Yellow Fever Vaccine Shows Promise in Mid
My comments and interview with @Medscape Next-Gen Yellow Fever Vaccine Hits the Mark in Mid-Stage Trial https://t.co/kFfGH4c5gt
View mRNA‑CRISPR as Molecular Surgery, Not Drugs
What if we started thinking of mRNA-CRISPR gene editing as molecular surgery, not as a pharmaceutical product? Excellent @nytimes guest essay ⤵️ https://t.co/S61XwNRVZF
Rapamycin Fails to Slow Epigenetic Aging, Sinclair Concedes
David Sinclair says rapamycin had no measurable effect on slowing or reversing epigenetic aging in humans. This was a drug most of the longevity community supported. He was even a believer of it. It was found to extend lifespan in: • Inbred lab animals •...
Speak Up Safely: Observe, Report, Protect Clinical Culture
No surgeon. No anesthesiologist. One physician. Packed ED. @jessicasinghmd stabilized a critically ill patient with blood in their airway. Shift ends. The incoming physician, also an administrator, says in front of staff: "I need you to function." She reported it....
Weight‑loss Drug Semaglutide Cuts Depression Risk by 42%
A 10-year study finds weight-loss drugs lower the risk of #depression and anxiety. Published in The Lancet Psychiatry, the #research revealed a 42% lower risk of #mentalhealth hospitalisation during periods of semaglutide use. https://t.co/CphnQl0Khx
Simple Ideas Spark Surprising Breakthroughs in Healthcare
Every now and then, remarkable breakthroughs come with a dash of ‘why didn’t I think of that?’ ingenuity. From reimagined everyday objects to solutions inspired by the natural world, these innovations prove that effective healthcare doesn’t always need to be...
Aging Biology Targets Key to Better Stroke Outcomes
Targeting the Biology of Aging in Cerebrovascular Disease: Inflammation, Metabolism, Senescence, and Regeneration 🔎Addressing age-specific pathophysiology will be critical for improving outcomes in cerebrovascular diseases in the aging population... https://t.co/DuScTnSIh5 https://t.co/Irok29jqMx
Regenerative Medicine Needs Data Over Hype
I recently had the opportunity to sit down with Scott Carney for a wide-ranging conversation on regenerative medicine, stem cells, peptides, and the growing gap between scientific promise and clinical reality. In the conversation, we dig into: – Why stem cell therapies...
Highest Healthcare Spending, Yet US Life Expectancy Lags
The US spends more on healthcare than any country on earth. The national average life expectancy is 77.5. Mississippi is 72.6. Source: Visual Capitalist https://www.visualcapitalist.com/mapped-us-life-expectancy-by-state/
Physicians Overpay Taxes—Learn How to Reclaim Income
Why physicians pay more in taxes and how to reclaim your income [PODCAST] http://dlvr.it/TRxTZR Podcast #PracticeManagement
Nursing Pays $80K+ Yearly, Fuels Entrepreneurial Dreams
This is why nursing is a great career choice. My wife was making good money at 21. In a major city hospital, you can easily make $80,000+ on 40 hours/week (on a side note, her income was the only way I...
Cearvol Nano OTC Aids Amplify Sound Anywhere
Wish you could hear everything around you, whether you're at a noisy restaurant or just watching TV at home? I check out the Cearvol Nano OTC Hearing Aids in various locations and find it's a great way to turn up...
Engineered Bacteria Consume Tumor Core, Overcoming Drug Barriers
JUST IN: Scientists built bacteria that EATS cancer from the inside out. The future of cancer treatment isn't a drug. It's a living organism that devours tumors from the inside. Here's how it works: Solid tumors have a dead center. No oxygen. No...
SIRT6 Gene Therapy Remains Safe, Effective in Aged Beagles
Genflow sees sustained safety and efficacy in SIRT6 beagle trial 🐶 “Genflow Biosciences reported that three-month follow-up data from its SLAB trial in aged beagles show sustained safety and efficacy of its SIRT6 centenarian gene therapy, with no adverse events and...
Statins for Seniors: Benefits vs Diabetes, Alzheimer Risks
Should older adults use statins for heart health? Do statins increase the risk of diabetes and Alzheimer's Disease? Dr. Gregory Charlop shares the results of an important new health study. www.buckheadlongevity.com/blog/should-older-adults-use-statins-a-top-atlanta-longevity-doctor-answers
OTC Hearing Aids Offer Affordable, Game‑Changing Solution
More hearing aids? Yes, because lots of folks have mild hearing loss, and OTC solutions are affordable and, honestly, game changing. This time I'm looking at the new Techmi FacePro OTC Hearing Aids in this demo and review: https://t.co/W0GUOshVxw #hearing...
New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/18HJ5kRuNj
Phase
#EAOnc EQUATE EAA181 Effective Quadruplet Utilization After Tx Evaluation: Ph3 RCT NDMM Not Intended for Early ASCT [Activated: 10/27/20] PI= @myelomaMD https://t.co/qD26HMx3J8 #NCT04566328 #mmMRD #mmsm @eaonc @mweissmdphd @VincentRK @LynneWagnerPhD Wei Snyder Kostakoglu @mtmdphd
Single Gene Therapy Dose Eradicates Brain Tumors in Mice
GENE THERAPY SAFELY ERADICATES BRAIN TUMOURS IN MICE A single dose of an innovative gene therapy could eliminate hard-to-treat brain tumours and prevent them from coming back, according to a pre-clinical trial in mice, reported in Nature. “More than 80 per cent...
Knight Cancer Institute Secures Record $2 Billion Gift
OHSU Knight Cancer Institute receives record $2 billion commitment from Phil and Penny Knight https://t.co/5rgDVaDUtv
Durable Bionic Prosthetic Ready for Real-World Use
A Durable and High-Performance Bionic Prosthetic Built for Real-World Use by @COVVI #Robotics #Innovation #EmergingTech #TechForGood #Technology https://t.co/9XKhPrkA8c
Dietary Amino Acid Restriction Shows Promise Against Pediatric Brain Cancer
Can rebooting the diet, eliminating 2 essential amino acids, help treat an aggressive brain cancer in children? mechanism and potential established from experimental model https://t.co/wmAFM2ErRB https://t.co/PAOr5SL30y
Statins Cut Mortality for Over‑80s Without Added Risks
Should people over age 80 use statins? The answer is increasingly: YES. A recent study found that patients over 80 on statins had a one-third reduction in mortality. Perhaps more telling, people who stopped their statins appeared to have a 1/3...
Flu Shot Cuts Alzheimer’s Risk Up to 55%
💉 Want to reduce the risk of Alzheimer' by 55%? A simple flu shot at the dosage recommended by the CDC for those 65 and older should do the trick. With 165,000 people in the study, they also...
AI Drug Discovery: Hype Overwhelms Real Clinical Success
AI Drug Discovery – Revolution or Expensive Illusion? | Ep. 978 https://t.co/YLQ8QNlnWv [ 00:34 ] Billions into AI drug discovery [ 01:04 ] AI doesn’t cure diseases [ 01:38 ] Expensive illusion vs reality [ 02:23 ] Original pitch inefficiency problem [ 03:48 ] Only 10...
Ansaras' Healthcare Investments Transform Haiti and Beyond
Jim and Karen Ansara have invested deeply in creating healthcare facilities in Haiti and other countries, with growing impact. Guest Contributor, Susan Barnett Reports: https://tinyurl.com/yc6e924m GlobalHealth
Lebanon's Emergency Services Collapse Amid Unpreparedness
‘We Were Not Ready for This’: Lebanon's Emergency System Is Hanging by a Thread https://t.co/dAYb1KGaD0 https://t.co/W11udn08dy
New Catalyst Quickly Builds Complex Molecules for Drug Discovery
A new catalytic method enables rapid, selective synthesis of branched molecules from simple, inexpensive reagents, streamlining early drug discovery and expanding access to complex molecular architectures. drugdiscovery
Trust, Not Software, Drives GLP‑1 Startup Success
If anyone can build a GLP-1 company for $50K, what actually separates the winners? I asked Josh Tauber and @keatonbedell on Lifers, their answer: not software. Trust. WATCH/LISTEN: Spotify: https://t.co/hrs0ZbILVz Apple: https://t.co/e8IxsoZ2bB Youtube: https://t.co/ORjNyzcOli
Early Cancer Detection Saves Lives—Don’t Wait for Symptoms
When cancer is found early, the chances for a cure are dramatically higher. The controversial part: most people never look. Don't wait for symptoms.
Two Cancer Startups Secure $237M for Antibody Innovations
A couple cool cancer drug startups profiled this week in TR. Sidewinder Therapeutics with $137M for bispecific ADCs https://t.co/tJcQwI7C4U and Stipple Bio with $100M for novel targets for antibody drugs. https://t.co/rbXkuaRpoe
Wedbush Flags One NKTR Dosing Interval as Unviable
You'll never guess which of these two dosing intervals Wedbush says "may not be viable" for $NKTR Rezpeg moving forward. Won't mince words - This firm is responsible for the worst sellside work I've ever seen. Sorry to be harsh,...
Greater Optimism Linked to Reduced Dementia Risk
No cause and effect established, but the more optimism the less dementia in >9,000 individuals with up to 14 year follow-up https://t.co/8pTnuJ9XSF https://t.co/Lcg4uExYrO
Adaptive Coherence Framework Guides Smarter Microbiome Health
We can be smarter about our microbiome health by cueing into host interactions, an "adaptive coherence framework" @cellhostmicrobe https://t.co/mprFgV7Gjq https://t.co/rQiPeK2aJP
Novo Undercuts Lilly with Pricier Wegovy; Insmed Braces for Flop
Novo underprices Lilly with higher-dose Wegovy; Insmed absorbs ‘expected’ study failure https://t.co/jN9GuuOf4s $NVO $LLY $INSM $VRTX $BIIB
2024 NIA‑AA Definition Connects Biomarkers Directly to Care
The 2024 NIA-AA biological definition of Alzheimer’s disease: linking biomarkers to clinical practice https://t.co/00cP1mXXHR https://t.co/VQ59YeIUR1
Genomics Predicts Individual Weight Loss From GLP‑1 Drugs
Genomics of GLP-1 drug response and side effects With genomic and demographic data it's possible to predict magnitude of weight loss response @23andMe https://t.co/iAS2Fjjxig https://t.co/AXsWnZw2Ub
Science-Backed Vaccines Protect Kids and Save Futures
My all time favorite ingredient of vaccines? SCIENCE. Follow the evidence. It is the safest place to be and the best way to protect your kids. Vaccinate your babies. Vaccines save lives and futures.
Modifying Gut Microbiome Boosts Memory, Slows Dementia
As a medical school professor, I teach that the gut-brain axis is real. But even I was surprised by this. A review in Nutrition Research confirmed: reshaping the gut microbiome can enhance cognitive performance and slow dementia progression. Key findings across multiple...
Quince Therapeutics: Today’s NASDAQ Wunderkinder Spotlight
And, of course, the day wouldn't be complete without a NASDAQ wunderkinder. Today's is Quince Therapeutics: https://t.co/SN5w5K1UCd
Genomic Drivers of Venetoclax Resistance in T(11;14) Myeloma
Genomic mechanisms of resistance to venetoclax in multiple myeloma with t(11;14)(CCND1;IGH) [Apr 2, 2026] @MKaddouraMD et al. @lbaughn @BloodPortfolio https://t.co/qmI6giPG6K #mmsm #PrecisionMedicine https://t.co/hpwUcavTg9
Never-Married Individuals Face 70% Higher Cancer Risk
Does never-married raise the risk of developing cancer? That what a new report says with a incidence rate ratio (IRR) of ~1.70 in both men and women. https://t.co/lz3wgagNRA https://t.co/ymwPqXT19x
AI Can Deliver Full Medical School Curriculum
On the future of medical education…. An “AI generated medical school” with “400 lectures for all four years — Over 1200 case studies, 16,000 figures and 20,000 quiz questions… a full curriculum map as well to track your progress…”...
RFK Jr. Pushes to Overturn Peptide Ban, Officials Dispute Claims
RFK Jr. May Reverse a Peptide Ban He Calls “Illegal.” Former FDA Officials Say He Mischaracterized Their Work. https://t.co/glqreTHvKA https://t.co/Vi4OTryX3p