Pharma Profits From Perpetual Prescriptions, Not Health
Big Pharma isn't in the business of making us healthy, they're in the business of keeping us on meds.
Insulin Spikes Can Halt Ovulation and Fertility
Most women don't realize that blood sugar issues can shut down ovulation. When insulin stays elevated, it suppresses something called SHBG, which means too much free testosterone begins to circulate. That excess testosterone interferes with follicle development and can stop the...
Health Canada Cuts Alcohol Limit to Two Drinks Weekly
Health Canada recommends limiting alcohol to just 2 drinks per week 🍷(In case you missed it, since 2023) https://t.co/44vxHDboSx https://t.co/hkhxyFe8fi
From Tin Hat to Systems‑Based Health Policy Insight
Sometimes I feel like a tin hat but I also studied in a field that focuses on the interconnected nature of systems and how these systems impact health And then I worked in policy, understanding how decisions are made about...
AI May Help Detect Rare, Often‑Missed Diagnoses
Nice piece @axios by @caitlinnowens on the use of AI by docs for diagnosis. She describes her mom's amyloid (rare & oft-missed multisystem illness) misdiagnosis. I'm not 100% sure AI would have helped, but it does have some unique skills...
Google's AMIE Shows Promise, Still Needs Clinician Partner
A great discussion by the brilliant @AdamRodmanMD on the new study of @Google 's AMIE (medical AI) tool, including the study's limitations. Bottom line is the tool's performance is impressive and getting better, but it's still best thought of as...
Periods Can Take Years to Return After Long-Term Birth Control
When I came off birth control after 13 years, I expected my period to come back within a month or two. It took 3.5 years. Most doctors will tell you your cycle should return within 3 months. For some women...
Drug Patents: Near-Term Generic Threat, Mid-Term Safeguards, Tirzepat
AI: Short-Term Cliffs (0-3 years remaining): Drugs like sacubitril/valsartan, dapagliflozin, pembrolizumab, ocrelizumab, daratumumab, and apixaban face imminent generic/biosimilar pressure Mid-Term Protection (4-7 years): Risankizumab and dupilumab have solid runway, supported by ongoing label expansions. Long-Term (8+ years): Tirzepatide's robust patents position it...
Judge Denies Epic's Dismissal Motion, Loss Expected
Another big Epic litigation update, as Judge Fillmore denied Epic's Motion to Dismiss in full in Texas v. Epic. It’s a loss, but somewhat of an expected one, as the state specific 91a pleading standard is a low bar. https://t.co/S9eI9qwFOV
Micro-Cages Enable Precise Manipulation of Cell Clusters
These micro-cages are designed to hold and manipulate tiny cell clusters in miniaturized lab-on-a-chip devices. https://spectrum.ieee.org/lab-on-a-chip-grippers?share_id=9241061
First Human Age‑Reversal Trial Targets Whole‑Body Reset
The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to...
NY AI Ban Shields Cartel, Ignoring Uninsured Crisis
New York wants to ban AI that outscores doctors on medical exams. Over 900,000 New Yorkers have no insurance. 92% of low-income legal problems go unaddressed. Anti-AI NY bill S7263 isn't consumer protection. It's cartel protection. https://t.co/e9BdWuvvUB
AI Sleep Model Predicts 130+ Diseases From PSG
SleepFM is a multimodal #AI foundation model for disease prediction. Developed by @Stanford researchers, trained on over 585K hours of polysomnography (PSG) data from 65K patients. It analyzes brain, heart, & respiratory signals to predict 130+ diseases—including dementia, cancer, and heart...
Exploring Tomorrow's Medicine with Global Leaders at ATOM
So proud to be on stage again with Serena at the ATOM event in LA talking to our dear friends Vartan Sarkissian and his father President Armen Sarkissian of Armenia 🇦🇲 about the future of medicine and healthcare 🧬 ATOM...
One in Six on Hospital Waiting List Amid Record Taxes
Wait? How is this possible. That would be 1 in 6 people are on a hospital waiting list? It's criminal how bad this countries health service is given we've had record tax income.
Vaccination Boosts Survival in Multiple Myeloma Patients
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmdKWV #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/L7r9caCcGN
Navigating Myeloma MRD: Risks, Benefits, and Treatment Decisions
MT @hhashmi87 #IMS25 Great Meet The Expert talk by @bdermanmd on MRD in Myeloma Risk vs benefit Who can stop treatment Active surveillance post discontinuation #mmMRD #mmsm https://t.co/YOBOPs7hQL
MRD‑Negative Patients May Stop Myeloma Maintenance Therapy
Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP) - @bdermanmd et al. @ajjakubowiak #ASCO24 Abstract 106 https://t.co/FBTY7SnCxK #NCT04108624 #mmsm #mmMRD
Clinicians Show Mixed Adoption of MRD in Myeloma
Clinician attitudes and practices toward measurable residual disease in multiple myeloma [Jun 7, 2020] @bdermanmd @jagoda_jasielec @ajjakubowiak Brit J Haematol https://t.co/8zhxYfYwZQ #mmsm #mmMRD https://t.co/QTlR2gv5Q0
Understanding MRD's Role in Multiple Myeloma Management
#mmMRD healthcare social media hashtag [Nov 21, 2020] Minimal/measurable residual disease (MRD) in multiple myeloma. Submitted by @bdermanmd to @symplur @healthhashtags https://t.co/grkkiox2yh #mmsm No longer available at Symplur https://t.co/IGDrNALHBP
Coffee and Tea Linked to Reduced Neurodegenerative Disease Risk
Consumption of coffee and tea and the risk of developing neurodegenerative diseases: a cohort study in the UK biobank https://t.co/bv0q79xKni
VR Lets Hospital Patients Explore Beauty Beyond Walls
A hospital room can feel very small. But the mind doesn’t have to stay there. At Cedars-Sinai, we’re using VR to help patients explore beautiful places beyond the four walls of the hospital room. Not to escape life… but to contemplate its beauty in...
Embrace Telehealth Early or Lose Clients Forever
Six years ago today, on Friday, March 13, 2020, I sent the email switching all my clients to telehealth. Some of them didn’t want to do online sessions; they said they’d rather wait a little, until things blew over. I...
AI to Autonomously Report X‑Rays Within Five Years
AI will likely report most X-rays near-autonomously within 3–5 years. We may soon have AI generating reports instantly… while radiologists still wait for the RIS loading wheel to open them.
SF Drug Crisis Stymied by Laws Banning Proven Solutions
Research SF’s drug crisis is like trying to fight a fire and finding out a bunch of laws passed that make using water to fight fires illegal. Then having to research non-water based solutions to large scale fires.
Shift to Proactive Planning Boosts MedTech Margins
New MPO article by Lisa Anderson: From Reactive to Proactive: planning strategies for Medtech customer and margin success. Ready to move from firefighting to proactive planning? Contact LMA. #MedTech #SIOP #SupplyChain https://t.co/6Kr0hpMRaq
Robotic Surgery Expands Into AI-Enhanced Precision
Robots’ potentials have been a fascination for humans and have even led to a booming field of robot-assisted surgery. Surgical robots assist surgeons in performing accurate, minimally invasive procedures that are beneficial for patients’ recovery. The assistance of robots extend beyond incisions...
Aging Outpaces Medicine in Cancer Risk Race
The longer we live, the more the cancer odds go against us. So it is a race between medicine and aging. More on this in the Chartbook Top Links today. https://t.co/RpUy2t9fij
Epic’s MyChart Fragments Records, Hindering True Interoperability
Class-action lawsuit claims Epic’s MyChart fragments patient records across portals, blocking full access & delaying disability claims. True interoperability still a challenge in digital health. https://t.co/jiKal8ggTl #DigitalHealth
CMS Delays Florida Direct Payment Approval for UHS
HEARING $UHS --negative call out right now- CMS has delayed Florida Direct payment approval due to CMS concerns-- capital forum confirmed
Epigenetic Therapy Marks New Era in Glaucoma Treatment
Great to see ophthlamologists adopting epigenetic modifications and resets to treat eye diseases like glaucoma. A paradigm shift in medicine https://t.co/g2gr3WVpkf https://t.co/6gbBVHJuXI
Congress Urges Curb on Costly Medicare Advantage Subsidies
Congressional advisers call to rein in Medicare Advantage spending amid industry pressure I’ll summarize for you. EVERY SINGLE FAMILY IN THE USA IS PAYING $800 A YEAR to the big insurance companies because taxpayers pay them more than it...
Midlife Joint Pain Signals Systemic Decline, Not Isolated Injury
I’ve been an orthopedic surgeon for nearly 30 years, and a few patterns have become impossible to ignore. One is that many musculoskeletal problems in adults aren’t sudden injuries. They’re the moment when declining capacity and awful metabolic health finally...
China Biotech Receives FDA Approval for First Cell Therapy Trial
With FDA go ahead, a China #biotech notches a first in cell therapy testing https://t.co/QorwJmou8w by @realJacobBell $XENE $BHVN
Measles Cases Surge: 92% Unvaccinated, 60% of Last Year
1. #Measles update: The total confirmed cases so far this year has risen to 1362 as of 3/12. Key context: The 2026 total to date is 60% of the 2025 total for the entire year. #CDC reports that among cases with...
Cancer Vaccines Show Promise for Hard-to-Treat Tumors
Cancer vaccines are showing marked efficacy vs refractory cancers and are going to be part of the future Rx armamentarium. Beyond that, ultimately, for prevention in high-risk individuals. A new stellar review @NatureMedicine https://t.co/PhtdZDtSBl https://t.co/okmwCD8AyB
Clinician Trust, Not Dashboards, Drives Sustainable Improvement
Lasting improvement doesn’t come from dashboards or mandates. It comes from clinicians who trust the data and own the change. A great conversation on what really works. 👉 https://t.co/SwV5qc59SV @HealthCatalyst #clinicalimprovement #HITSM
Adults' Diagnosis Denial Won’t Aid Children’s Care
It is not clear to me how denying diagnosis to adults like me would get children more medical help.
Amyloid Antibody Therapy Triggers 100 Microhemorrhages in APOE4 Patient
100 brain microhemorrhages in a patient with cerebral amyloid angiopathy and 2 copies of APOE4 after amyloid antibody therapy https://t.co/ASpVuijFNW https://t.co/hdtwtv1usq
LAG‑3 Checkpoint Suffers Another Trial Setback, Focus Shifts
NEW: Another failure in the clinic in the world of LAG-3, a target once seen as possibly the next major checkpoint inhibitor after PD-1 and CTLA-4. My latest on Immutep's Phase 3 disappointment, as LAG-3 focus now shifts to a...
Seeking NHS Waiting List Insights for Upcoming Piece
@angelazhay - I'd be keen to make contact with you to discuss NHS waiting lists for a piece I'm working on. Could you reach me on laura.donnelly@telegraph.co.uk?
De Novo Enzymes Redefine Peptide Therapeutic Production
Peptide therapeutics are powerful. But making them has always been difficult. Traditional chemical synthesis can involve long routes, poor selectivity, and significant environmental impact, while biological production is often limited by the pathways evolution happened to provide. What if we could design...
HSV-1 Reactivation Linked to Faster Aging, Dementia
The reactivation of herpes simplex virus (HSV-1, not only herpes zoster) may be tied to accelerated aging and dementia, and account in part for the mechanism of Shingrix vaccine''s protection @WIRED https://t.co/iKF1JcYSu0
Biotech Layoffs Hit Evotec, Vistagen; Immutep Shares Plunge
Evotec, Vistagen lay off staff; Immutep shares collapse on study failure https://t.co/OikmCdJ6sg $EVO $VTGN $IMMP - 81% $RARE $ATRA
Patients Should Drive Aggressive Immunotherapy Post-Remission
Merkel cell carcinoma log, day #594. Yesterday, I was at Dana-Farber for my first infusion of avelumab in more than 3 months. Aside from two botched blood tests — the buzz is the blood tests are being done with recently...
New Drug May Replace CPAP for Sleep Apnea‑Heart Risk
On @fox5ny with @stevelacy and natashacurrytv discussing the very real connection between sleep apnea and heart disease. There may be a drug therapy on the horizon to free us of the clap machine. @helloheartapp @morehouseschoolofmedicine mag1849_ medical_association_of_atlanta
White House Declares Vaccine Debate over, Eyes MAGA‑MAHA Alliance
“We’re just kind of done with the vaccine issue,” said one White House official. “We’ve done what we want to do on the vaccine front.” On the future of the MAGA-MAHA alliance, w/ @ChelseaCirruzzo https://t.co/g6goE2TC6e
5‑Minute Calcium Scan Beats Cholesterol for Heart Risk
The Coronary Artery Calcium Scan - The Heart Disease Test You've Never Heard Of There's a 5-minute heart scan… No needles. No treadmill. No contrast dye. And it predicts heart attack risk better than cholesterol alone. https://youtu.be/XVNLubDAE-M
White House Must Nominate CDC Director by March 25
On the clock: The White House has until 3/25 to nominate a new #CDC director. The Federal Vacancies Reform Act states a job like CDC director can only be filled on an acting basis for 210 days from the creation...
Healthcare Spending Jumps 7.9%—Outpacing Inflation
Spending on healthcare services is up 7.9% year over year, far higher than the inflation rate reported in the CPI https://t.co/Mt0STaWkJz