
Mitochondrial Transfer Shows Promise Against Parkinson’s in Animals
Potential of mitochondrial transfer to prevent or treat Parkinson' s disease, in mouse and monkey models @CellCellPress https://t.co/c0oqfagddX https://t.co/KyBc1zQttc
Comparing Psychedelic Trials to Antidepressants Skews Results
Does it stack the deck in favor of the standard antidepressants to pull data from placebo-controlled trials for one condition (the psychedelic) and compare it with single condition data for the standard antidepressants? Also...

AI in Healthcare Fails Without a Digital Strategy
80% of healthcare practices that invest in AI automation fail to see ROI. Not because the tools don't work, but because there was no digital strategy. Don't be the 80% See more & JoinUs https://t.co/05FgGDavR7 #healthcare #ai #businessautomation #smallbusiness #medical #doctor...
Hire Experienced Tech Auditor for Healthcare Apps, HIPAA Compliance Critical
If you are vibe-coding apps for the healthcare sector I beg you - pay a deeply experienced technologist to audit it before anyone uses it. hipaa laws are no joke. I’ve personally been through the compliance audits, defending our encryption...

Geroscience Should Prioritize Healthspan, Not Just Lifespan
From a clinical perspective, patients are not asking for abstract years. They are asking for time with family, time in full cognition, time in independence, and time living on their own terms. That is why geroscience should be judged not...
Profiting From Out‑of‑Network Bills, and the Fury It Sparks
How to get rich on out-of-network medical bills -- and how to get angry reading about it. By @TaraBannow https://t.co/fbmFyZhcic
Excalipoint Secures $69M for Next‑Gen T‑Cell Engagers
Chinese biotech startup Excalipoint banks $69M for next-gen T cell engagers https://t.co/809RqRWJNL by @gwendolynawu #biotech #startups

Invest Now: Top 24 Digital Health Tech Trends
AI and Digital Health are booming. In this book, we explain why now it's a good time to invest in Digital Health and give recommendations on where to invest by looking at the top 24 technological trends we find the...

Medical Residents Endure Toxic Culture, Power Imbalance Fuels Burnout
Medical residents are the backbone of the hospital system. They are also its favorite punching bag. We expect them to work 80 hour weeks. We expect them to accept low pay. But we also force them to endure systemic disrespect, microaggressions,...

SUNMED IPO Soars 17% Above Price, Expansion Funded
Sunway Healthcare Holdings Bhd (SUNMED, 5555) debuted strongly on Bursa Malaysia Main Market today. Opening price hit RM1.70 → 17% above IPO price of RM1.45. Price climbed fast to RM1.80–RM2.00 range in morning trade → market cap exceeded RM20 billion. Retail offering...
Chargemaster Inflates Prices, Patients End up Paying the Cost
When I was at the Brigham/Harvard I saw how we billed different insurance levels as well as the uninsured. The uninsured got screwed the worst. Always. Different payers pay remarkably different prices for the identical things. It all comes down...

Demanding Colorado Reinsurance Cost Transparency From Governor
How about we ask @govofco how much more reinsurance is costing Colorado? And don’t give me the bs talking points about the average premium reduction, babes.
Policy Secures Health Coverage for 27,000 Colorado Families
Yesterday one of my co-conspirators messaged to let me know that over 7k pregnant people and 20k children have health coverage because of the policy we passed years ago…Cover All Coloradans I have so many feelings that I can’t fully figure...

Largest Review Finds No Evidence Cannabis Relieves Anxiety, Depression, PTSD
No evidence that medicinal cannabis effectively treats anxiety, depression, or PTSD - according to the largest review of cannabinoids ever conducted.
Earn 50 CME Credits in Compassionate End‑of‑Life Care
BEING WITH DYING: Professional Training Program for Clinicians in Compassionate Care of the Seriously Ill and Dying (In Person 2026) May 8-15 50 CME's for clinicians https://t.co/nt2OWCudf6
US Smoking Rates Dip Below 10% for First Time
Cigarette smoking in the US falls below 10% of the population for the first time. https://t.co/JReSJgZA85
Retatrutide Drops Weight Fast, but Triggers Severe Reflux
So it's time for an update on me playing around with Retatrutide. This is typed from mobile, so forgive any typos or missing words. First, I stopped using it about 2 weeks after post below. I didn't run out. I'm just...

AI's Real Bottleneck: Accelerating Human Processes, Not Tech
Our bottleneck for some of the biggest change ahead may be humans. I shared the story of Paul Conyngham and his dog Rosie on my Instagram when it broke. When I read the coverage, my shock was less that ChatGPT...

Smart, Connected Care: The Future Hospital Unveiled
Hospital of the Future — Advancing smart, connected care through data-driven innovation. Join me for a deep @DigitalDHealth dive with @StephenKonya @jconleymd, Manish Ladha, and Casey Granak This Thursday at 10am PST / 1pm EST for our https://t.co/YGpenFx8zW Studio Series Register here-->...
US Postpartum Women Denied Essential Pelvic Floor Therapy
In France, women who give birth are routinely prescribed pelvic floor rehab. They get about 10 sessions with a physiotherapist covered by the government. This has been standard since the 1980s. In the US, you get a 6 week...

Feedback System Enhances Gait and Perception in Knee Prostheses
This week's Editor's Choice highlights a study by Valette and colleagues that evaluates a feedback system to improve gait and perception when using a knee prosthesis. @rlvalette Learn more in Science #Robotics: https://t.co/pWQ3r6aGLs https://t.co/xqUZp2YyCH
Complement Proteins Predict Dementia Risk over a Decade
Adding complement proteins to the blood testing schedule is in the arena Systemic complement factors in aging, Alzheimer’s disease and other dementias: a longitudinal study over 10 years https://t.co/qDwmnbxHHY

GIP Drives Subcutaneous Fat Storage; Tirzepatide Leverages This
GIP preferentially enhances glucose storage and triglyceride deposition in healthier subcutaneous fat, particularly under conditions of hyperinsulinemia and hyperglycemia. Tirzepatide contains a GIP agonist. https://doi.org/10.2337/db10-0098 https://www.gatlan.com/ @GatlanHealth
Every 60‑Second Delay Increases Patient Risk
It’s not one big delay that hurts care. It’s 60 seconds… repeated 100 times a day. Marianne Soucey explains how tiny workflow friction turns into real patient risk ↓ https://t.co/UjbpWUtOH1 @ConsensusCS @medq_inc #RSNA25 #HITSM https://t.co/6X9UwqHjHx

Pro Se Lawsuit Targets Epic to Circumvent Texas Malpractice Rules
A pro se plaintiff just sued @HeyEpic in federal court, arguing its EHR architecture is a defective product. But sneakily, I don’t think it’s about Epic at all: it's a discovery pathway around the Texas malpractice rules that froze her...
Unregulated Online Market Sells Ketamine for Depression Relief
Ketamine, an operating-room anesthetic also prized as the street drug “K” is now at the heart of a largely unregulated online industry offering depression relief. https://t.co/pGd0TO5uFy via @WSJ
Bicycle Cuts 30% Staff, Abandons Padcev Challenger
Bicycle to lay off 30% of staff, pivot away from Padcev challenger https://t.co/m3JFu2mwoB @ByJonGardner $BCYC $PFE $MRK

Corporate Life Accelerates Diabetes and Hypertension in Indian Youth
Corporate life is damaging the health of Indian youth. According to reports 1 in 4 men aged between 31–35 shows pre-diabetes or high BP risk. The reasons behind this are: Long sitting hours Stress Poor sleep Junk food Pushing all corporate professionals into lifestyle diseases much earlier. Men...
Pfizer's Ibrance Successor Advances with Fresh Study Data
Pfizer’s Ibrance successor moves forward with new study data https://t.co/ozXAZYmc3M by Kristin Jensen $PFE $LLY $NVS $RHHBY $ONC

GLP‑1 Weight Loss Shows No Extra Muscle Loss
A study asserts lack of disproportionate loss of muscle mass or strength cf weight loss from GLP-1 drug treatment, in mice and a small short term (12 weeks) trial in men The issue remains unsettled and counters the efforts by companies...

Single-Cell Analysis Advances Neurodegenerative Disease Understanding
Neurodegenerative diseases at the single-cell level, a powerful tool to differentiate and better understand https://t.co/Pkz4qW0ELM @jclinicalinvest https://t.co/LiJ4FojRYZ
AI Augments, Not Replaces, Doctors in Future Healthcare
Much of the conversation around healthcare and AI right now pits doctors and AI against each other. This is the wrong framing. Yes, it is important to have studies that look at how good AI is at various tasks that physicians...
Physician Burnout Stems From Lost Authority and Opacity
This week on Lifers, Graham Walker is “sounding the alarm” for physicians. * 50% of medical students already plan to quit before they finish school. * Doctors are becoming "factory employees," losing their authority to care for patients. * Tech focuses on the...

CytomX CRC Data Demand Double‑Take, Not Clear Verdict
Some clinical updates tell you exactly what they are. Others ask to be read twice. CytomX’s latest CRC data belong firmly in the second category. Is the die cast? https://t.co/dfdPxx4zXs https://t.co/y9QAoahMut

Apply Proven Futures Methods to Shape
Analyzing the future of medicine and healthcare, especially during the rise of digital health and artificial intelligence, should rely on established futures methods that the discipline of futures studies has been using for decades. By employing such methods, healthcare professionals,...
Trump Pushes Drug Pricing Overhaul Despite Congressional Resistance
The Trump administration is "gearing up for war" to push Congress to codify its drug pricing policy — despite little appetite for it on the Hill. Still, the pharma industry sees risk in the back-and-forth. https://t.co/DR2LotvXFq
Paralysis Patients Type Using Brain‑computer Interface
A brain-computer interface allowed people with paralysis to type with their minds https://t.co/W5icU6ye8c via @statnews

Mechanical Forces: Emerging Tools for Diagnosis and Therapy
Mechanical forces play essential roles in biology. Measuring and controlling these forces represent emerging strategies for disease diagnosis and therapeutic intervention, to complement more traditional approaches. This review article, published today in Nature Reviews Bioengineering (https://t.co/byKGFuVFLH), summarizes the status of...
Roche Launches Biggest Hybrid‑cloud AI Factory with Nvidia
At 3,500+ Blackwell chips, Roche is building the "largest announced hybrid-cloud AI factory" in biopharma with Nvidia: https://t.co/99Eih7EnRD
R1 Secures $78M to Advance Kidney Drug Development
R1 starts up with $78M, aiming for a better kidney drug https://t.co/PQQjX47ODM by @gwendolynawu #biotecjh #startups
New Drug Could Eradicate Sleeping Sickness, Says NPR
Sleeping sickness could be wiped out with this new drug: my comments @NPR @NPRGlobalHealth https://t.co/T0mAeX8P0A
Women Pay $4,700 Extra Yearly for Hidden Health Costs
Women spend an estimated $4,700 more per year in out-of-pocket healthcare costs than men, for conditions that often go undiagnosed for a decade. Who built this system and who did they build it for?
Forgotten Victims: Forced Sterilizations in India Ignored
Where's the obituary for the millions of poor Indians who were forcibly sterilized by international programs directly inspires by Ehrlich's work? Or would that story be "premature"?

Women Comprise Two‑thirds of Alzheimer’s; Midlife Origins Examined
Why do women account for nearly 2/3rd of all cases of Alzheimer's disease? A new, thorough review @jclinicalinvest, open-access, on its origins in midlife. https://t.co/obITwhEiYG https://t.co/RXBffM9jKV

Combine GLP‑1 Drugs with Better Sleep for Optimal Health
An estimated 30 million Americans have obstructive sleep apnea. GLP-1 medications are producing weight loss at a scale we haven’t seen before. A 20% loss makes apnea 53% less severe. Something that doesn’t get enough attention: sleep is a metabolic intervention....
Doctors Discourage Early Mammograms yet Still Find Issues
i got an elective mammogram earlier this year (im 31). they found something concerning before we knew what it was: "thank god you came in early" after we (thankfully) found out it was benign, same doctor: "you really shouldn't be getting...
Judge Stalls Kennedy Childhood Vaccine Overhaul Meeting
Kennedy childhood vaccine overhaul stalled by judge The next meeting of the Advisory Committee on Immunization Practices was scheduled for this week, but has been postponed due to the ruling https://t.co/0cUIXEVgyV
Court Deems Kennedy Vaccine Schedule Rewrite Likely Illegal
A big — if preliminary — win for #AAP and pro- #vaccine policy today. A court has ruled Robert Kennedy's reconstitution of #ACIP and his department's rewriting of the childhood vaccination schedule are likely illegal. Developing story. https://t.co/0lMSGQrayz
New AHA/ASA Guideline Optimizes Early Acute Stroke Care
2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association https://t.co/YToJnO22Zx
Medicine Needs Blended Intelligence, Not AI vs Doctors
AI can read the chart. But it can’t read the room. Today a patient’s story revealed something the algorithm didn’t flag. The future of medicine isn’t AI vs doctors. It’s Blended Intelligence, or “BI.” We need both. More in the video below 👇 https://t.co/7iwPleaAJD