Doctors Need Stability First, Healing Second
most of us chose medicine for the love of healing and the satisfaction of seeing patients recover, not for ego or glory, and money was meant to be a by-product. But after years of hard work, investment, and burnout, if doctors can’t meet basic needs, something is wrong. We’re humans first, healers second. You can’t pour from an empty cup. Stability first, service next. That’s not ego, that’s sustainability.
Doctors' Biggest Mistake: Settling for a Safe, Stagnant Career
🧵 The biggest mistake doctors make isn’t choosing the wrong branch. It’s choosing the safe life without questioning it. You study for years. Get the degree. Take the job. Everything looks right. But slowly: • Income plateaus • Workload increases • Freedom decreases
UniQure Bet Turns Into FDA Shitstorm and Short‑sell Speculation
I bet on uniQure thinking it was an obvious win win win. HD wins with expanded access. FDA wins by narrowly expanding authorization while vigorously monitoring follow up data. Investors win as the company proves what doctors are saying. Instead...
SGLT2 Inhibitors Boost Survival in Frail Seniors
Use of SGLT2 Inhibitors in Frail Older Adults is Associated with Increased Survival: A Retrospective Study https://t.co/tsJ5qJLBap https://t.co/4EvBWDftJ4
Moderate Wine Drinkers Cut Heart Death Risk 21%
A new study of more than 340k British adults finds that moderate wine drinkers (1-3 glasses/day) have a 21% lower risk of dying from cardiovascular disease versus people who never drink or do so occasionally. I will be accepting no...
Short Telomeres Reveal Accelerated Kidney Aging, Predict CKD
Researchers found that shorter telomeres and DNA changes in kidney cells may signal faster biological aging of the kidneys and help predict risk for Chronic Kidney Disease earlier than current methods. 🧬 https://t.co/JKRM7xhOnh
Henagliflozin Shows Potential Anti‑Aging Effects in Diabetes
Effect of henagliflozin on aging biomarkers in patients with type 2 diabetes: A multicenter, randomized, double-blind, placebo-controlled study 🔎"Our results suggest that henagliflozin may exert anti-aging effects by influencing multiple pathways, including the IGF-1 system, glucose metabolism, the immune system, and...
Physicians Must Choose Health Over Exhaustion, Says Dr. Mitchell
It takes the human brain two years to fully recover from burnout. Yet many physicians are in denial, assuming their absolute exhaustion is just normal. Dr. Tomi Mitchell hit her absolute limit. She was running a massive medical center, raising two...
Insurance Fees Undermine Care: Doctors, Nurses Underpaid
Des and Nurses are underpaid. Independent doctors are getting ripped off to the point of barely getting paid after fees The biggest insurance companies are awful for beneficiaries and for employers. One example ? What good is insurance if patients...
Vaccines Save Lives—Get Free Resource Guide
Vaccines save lives. Ask in the comments if you have questions. As a subscriber to my Substack you get a vaccine resource guide available for download and as a paid subscriber a 64 page guide on vaccine preventable diseases.
Democrats Ignore Healthcare Fraud, Ceding Narrative to Republicans
Some of this healthcare fraud video stuff is of course performative and bad use of data. But a lot of it isn't. Yet, not a single Dem that I'm aware of at national/state/big city level is making the case for...
Thin Legs Strongly Predict Higher Mortality Risk
There is a similar study for thigh circumference - turns out that thin legs are one of the best predictors of mortality. https://t.co/v6H3jYNXrY https://t.co/PkaQPvyrpX https://t.co/0cOR1L7ZnM
YC Proves Its Worth in Biotech Startups
Interesting collection of YCombinator biotech startups this batch. I had been skeptical that YC could work at all in biotech, but I've been proven wrong over the last couple of years.
Oracle Accelerates AI-Driven Healthcare Innovation with Partners
Loved sitting down with @DrSharma_NY earlier this month for a fireside chat at Health Tech Summit 2026! Grateful for the opportunity to share how Oracle is working with our customers and partners to advance AI-driven innovation in healthcare. Thanks to the The Health...
Sharing Lifestyle Medicine with 1,000+ Primary Care Professionals
Delighted and honored to speak to the over 1,000 participants in the Brigham Women's Hospital CME course titled Office Practice of Primary Care Medicine yesterday, via Zoom at 4:55 pm, at their last session of a powerful week of presentations. The...
Sewage Surveillance Detects Colorectal Cancer Biomarkers Early
Wastewater Detects Colorectal Cancer Biomarkers What if your city's sewage could detect cancer before your doctor does? As a medical school professor, I find this remarkable. Researchers tested neighborhood wastewater in Kentucky for colorectal cancer biomarkers using droplet digital PCR. They detected CDH1...
$101 Million Contest Aims to Extend Human Healthspan
There's a $101 million competition happening right now to extend human healthspan. Not in mice. Not in worms. In people. https://x.com/robertlufkinmd/status/2035318955821375489
Direct Medicare Advantage Enrollment Sparks ACO Competition Debate
Great review of the idea of potential enrollment right into Medicare Advantage (though doesn’t consider Chris’ added twist of competition between Traditional Medicare ACOs and MA) https://t.co/rcquVZ8zxn it would be fun to compete head-head (but would need level playing field)
Good Medicine Prioritizes Integrity Over Perfect Patient Scores
A 100 percent patient satisfaction score does not always mean you are a great doctor. Sometimes it just means you are a people pleaser. Physicians are conditioned to panic over negative feedback. One bad review can trigger a complete nervous system...
We’re on the Brink of Self‑directed Human Evolution
When I was talking to Sergiy Velychko, a former postdoc from George Church's lab, about the future of human genome engineering, we discussed: “We're now at this point where we can engineer ourselves. We can do stem cell therapies. We can...
Frailty and Inflammation Extend Geriatric Unit Stays
Frailty and inflammation predict prolonged stay in post-emergency geriatric units: a retrospective cohort study https://t.co/92P3HSm6LS
Repealing ACA Worsened Healthcare; Original Law Still Insufficient
The Republican efforts to dismantle the ACA absolutely made things worse but even if they’d left it alone the legislation still wouldn’t have fixed our health care system
Exercise Boosts Quality of Life in Mid‑to‑Late Adulthood
Physical exercise and health-related quality of life in mid- to late-adulthood: a multi-group chain-mediation analysis https://t.co/vd6yqa45rx
Back Pain Care Fails Due to Financial Incentives
Over half of all lumbar fusions fail. They’re still covered by insurance. Conservative care that actually works — exercise, PT, load management — gets denied or severely limited. We don’t have a back pain problem. We have a financial incentive problem.
FDA Must Add Spot Checks for Generic Drugs
Read “Bottle of Lies.” FDA needs to perform spot checks of generics - not just inspections.
Diverse Nursing Approaches Enrich Patient Experience
I've been a dad for five days - and somehow, it's already made me question what I thought about AI and the patient experience. Lemme explain… We had an incredible experience in the hospital. Not because of any Tech… but because...
Endometriosis Impairs Egg Quality—Strategies Boost Longevity
Endometriosis and Oocyte Quality: Morphological Alterations, Developmental Competence, and Modifiable Strategies for Reproductive Longevity https://t.co/I2ZrtJkguK https://t.co/LkH3LXzkcg
Trump Health Chief Proposes Automatic Medicare Advantage Enrollment
Automatic enrollment in Medicare Advantage plans under consideration, top Trump health official says https://t.co/Bgv6WBeo2u via @statnews
DOT's New Allergy Rule Endangers Flight Safety
How the new DOT ruling on food allergies threatens air travel safety http://dlvr.it/TRcKjc Conditions #AllergiesImmunology
Too Many Opinions, Too Few Answers: Trust Physical Therapy
Fun day .. “You’re my 5th opinion.” Knee injury These are usually a problem. Previous 4… -Only one exam -All repeated X-rays -2 MRIs. - One Special NY hospital often insists their MRIs...
HHS Weighs Appeal of Controversial Vaccine Schedule Ruling
To appeal or not to appeal (yet): The potentially politically dicey situation facing HHS over a preliminary court ruling this week on #ACIP and the rewritten childhood vaccination schedule. By @ChelseaCirruzzo. https://t.co/3P1PW1lDFT
Debunking Stem Cell Hype: Honest Talk on Medical Misinformation
I will NEVER miss an opportunity to call out medical misinformation so people know how to protect themselves and rally for change. On this particular panel, we got into the hype and hope of stem cells in an honest and cathartic...
Lilly’s Biz Dev Handles 10 Weekly Deals, Public Offers Stalled
Some interesting comments from Jacob Van Naarden, $LLY head of business development, at STAT's Breakthrough Summit East event yesterday: On deal volume: Jake, himself, is seeing approx 10 deals per week, ie deals that are important enough, or diligenced enough,...
Spotting Evidence-Based Longevity Clinics vs Marketing Hype
One of the questions I get asked most often is how to tell the difference between a longevity clinic built on evidence and one built on marketing. It's a question that deserves a honest, detailed answer. Grateful to be sharing the...
Inside the CDC Director Search: Leadership Insights
If you care about the future of the CDC or public health, you need to read this piece and watch this video on how leadership is thinking about the search for a new director. Definitely watch the 10 minute video in...
CDC Director Vacancy Persists; HHS Races to Fill Role
If you've been following the situation at #CDC — specifically the agency's lack of a director for most of the past 15 months — you'll want to listen to Chris Klomp, chief counsellor to HHS, discuss the administration's search for...
Speed of Execution Beats Perfect Health IT Roadmaps
The question in health IT isn’t who has the best roadmap It’s who can execute fast enough. David Cohen’s perspective from the Greenway User Conference: https://t.co/N0sw9cW6oH @greenway #EHRstrategy #HITSM
AI Agent Lets Clinicians Document without Sacrificing Patient Care
In hectic settings like emergency departments, clinicians shouldn’t have to choose between caring for patients and keeping up with documentation. @OracleHealth Clinical AI Agent is designed for the realities of emergency and inpatient care. https://t.co/P3gcSvXwCJ
Phase 3 Trial
.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/acq0EeyNFn
Phase 2 RCT Compares Dara‑
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/s8eqQJkQzK
Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/lI3MqKHIiY
Hospital Stress Can Halt Labor; Safety Boosts Birth
So many women labor beautifully at home and then everything slows down the moment they get to the hospital. Contractions space out, weaken, or stall completely. Then they're told they've "failed to progress." There's a real physiological reason this happens....
Flu Deaths Surge: 85% of Kids Unvaccinated
1. A #flu update: 14 more kids have died from flu this season, per #CDC. This brings the 2025-26 pediatric flu death tally to 115 so far but it's likely to continue to rise. At this point last year the...
Living-Cell Robots Gain Self-Contained Nervous Systems
Robots Made From Living Cells Get Upgraded With Their Very Own Nervous Systems https://t.co/ctQ64b45O4 https://t.co/ye1TV6VwCn
Patients Should Expect Doctors to Use Clinical AI
At this point, it's very reasonable for a patient to ask their doctor, "Have you used clinical AI to help optimize your diagnosis and treatment plan for me?"
Health Experts Discuss Vaccine Shifts, Funding, ACA, and Solutions
On this week's #WTHealth pod: @LaurenWeberHP, @sangerkatz, and @AliceOllstein on vaccine changes, NIH funding, the ACA and more. Plus @DrewAltman kicks off our new series, "How Would You Fix It?" https://t.co/GYkk11Hv6L
Companies Hide Device Risks, Harm Thousands
This is a recurrent fiasco. Health care companies that now the serious risk of their device or drug but keep selling it and do not acknowledge the hazard. Until so many people are harmed. Today's front page @nytimes by @katie_thomas @bostonsci...
US Plasma Sales Power Billion‑Dollar Industry, Aid Lives
The US lets people sell their blood plasma, creating a multibillion-dollar industry (70% of global supply, 62.5M liters donated, $6.2B in exports) that saves countless lives and gives Americans a safe way to make a little cash (thus reducing their...
Biotech Godfather Stelios Papadopolous Joins Garde on Podcast
This week's Readout LOUD podcast is now available on all your favorite podcast outlets -- Stelios Papadopolous, the ‘godfather’ of biotech, in conversation with @damiangarde https://t.co/RHh5Qv9OyT via @statnews
Higher Fitness Linked to Lower Dementia, Depression, Psychosis Risk
The relationship between increased cardiorespiratory fitness (METS) and reduced risk of all-cause dementia, depression, and psychotic disorders. From over 4 million individuals in 27 studies @NatMentHealth [association, not cause and effect evidence] https://t.co/iQdGRc0Nrz