MRK Likely to Rerun TERN Study for Data
Based on previous form $MRK will probably now rerun the $TERN study, just to prove to itself that the data were real.
Analysts Bullish on MAZE, yet Pre‑market Price Drops
$MAZE - Analysts pitching tent poles over the AMKD data, yet stock is down pre market. What's the disconnect?
Affordable €2000 Robot Offers Elderly Care and Home Automation
This robot was designed for elderly care. It can have conversations with the user, measure blood pressure and heart rate, operate the smart elements of the house from heat to lights and do simpler tasks. It's quite the accomplishment (or claims) for...
Kidney Disease Hijacks Gut Microbiome, Accelerating Decline
As a medical school professor, this is one of the most terrifying feedback loops I've seen in medicine. UC Davis researchers just published in Science showing how chronic kidney disease hijacks gut bacteria to destroy your kidneys FASTER. The mechanism: 1. Damaged kidneys...
Merck Spends $6.7B on CML Drug Despite Gleevec Era
It's amazing that 25 years after Gleevec we are still watching drug companies pay billions for new drugs for CML. And that, in Adam's previous story, a once deadly cancer was referred to as a chronic disease. Anyway, $MRK buys $TERN...
Vitamin D Guidelines Miscalculated; Sunlight, Not Pills, Solves Deficiency
The Vitamin D Lie Your Doctor May Still Believe The official recommendation was based on a mathematical mistake. The "normal" level on your lab report may be dangerously low. And the best fix isn't a pill — it's free https://x.com/robertlufkinmd/status/2036754584954167391
AVXL Withdraws Alzheimer's Drug From EMA After Rejection
$AVXL pulled its blarcamesine Alzheimer's application from the EMA after regulators there said there was no fking way it was going to approve a drug that does not work.
Actionable Monitoring Beats Data Overload in Cardiac Care
Health care has become better at saving people once they are already in trouble. That does not mean we have become good at catching trouble early. This episode of The Podcast by KevinMD gets at a hard truth in cardiac care: we...
Rubber Dams Enable Precision in Modern Dental Care
Why Rubber Dams Matter in Precision Dental Procedures by @IntEngineering #MedTech #HealthTech #Tech #Healthcare #TechForGood https://t.co/cRySPYX43q
Perimenopausal Women Remain Grossly Undertreated in Orthopedics
Nearly 30 years in orthopedic surgery. Another pattern that is impossible to ignore. Perimenopausal women are some of the most undertreated patients I see. One unfortunate paper is blamed... but often, it's because the conversation never happens. https://t.co/6m6AxUhRKF
Lyme Disease Isn’t a Bioweapon, Says Immunology Researcher
Since Lyme Disease is suddenly getting more attention than usual: Hi! I’m a researcher and scientist getting my PhD in Immunology, Infection and Epidemiology. I’ve been studying tick feeding and Lyme Disease for over 5 years now looking for an anti-tick...
VC Frenzy Risks Unsafe, Profit‑driven Psychedelic Clinics
So I know everyone's really excited about psychedelics and I mean. Me too kind of. You know what I'm not excited about? The fact that every venture capitalist under the sun is throwing money at this right now (trust me, a...
Exercise Protects Blood‑Brain Barrier, Slowing Alzheimer’s
New on exercise —the best medicine vs age-related chronic diseases, a review @Cell_Metabolism https://t.co/z9RpD0SlYW —salutary effect on the blood brain barrier (BBB) vs Alzheimer's and brain aging gift link https://t.co/jmhJwXGWms by @GretchenReynold —original research on BBB integrity via liver produced exercise factor @CellCellPress https://t.co/3tSN8knpYF
Pre‑existing Conditions Aren't Covered—It's Not Insurance
Ignoring preexisting conditions is not insurance and people shouldn’t pretend it is. Myth #3 https://t.co/vlKp7E5lKj
Insurance Deductibles Turn Hospitals Into Subprime Lenders
The are a function of health insurance plans. The insurance companies create plans with deductibles that most people can’t afford. So to get to the insurance money from their plan, they will loan the patient money to cover...
Glass 5.5 Delivers Specialty‑focused AI for Clinicians
Glass 5.5 is an amazing upgrade to the platform. Clinicians now have an AI specific to their specialty that will support them through every step of their clinical workflows.
Choose Exercise by Goal, Not One‑Size‑Fits‑All
The relative effects of different exercise modes on physical and metabolic health in older adults: A network meta-analysis "Current evidence does not identify a single “best” exercise modality for improving VO2max/VO2peak in older adults. Modality selection may be better guided by...
AI Diagnosis Systems Match Doctors, Cut Triage Errors
Results are in and crystal clear on which systems are best in medical diagnosis and how high the concordance is with human physicians. And very low triage error rates
AI-Driven Oracle Solutions Cut Costs, Boost Healthcare Profitability
Oracle’s clinical, financial, or operational solutions to lower care costs and improve profitability. https://t.co/MbG4q9k5EM Learn how our AI-powered solutions can help your organization streamline operations and enhance care delivery. https://t.co/rLxc2XEx47
U.S. Power Cut Threatens Cuban NICU Babies' Lives
The U.S. continues to attempt to kill more babies. The American govt is 100% culpable for this suffering and could end it at any time
NEMT Must Adopt Closed‑Loop Interoperability for True Modernization
Trip intake in one system. Fulfillment in another. Claims somewhere else. That’s not modernization. Why NEMT needs closed-loop interoperability: https://t.co/xVhBAUMx5u @KinetikHealth #NEMT #HITSM
One in Five Claims Denied Sparks Systemwide Frustration
When one out of five health insurance claims get denied, you can understand why patients, doctors, and hospitals get frustrated. https://www.kff.org/patient-consumer-protections/claims-denials-and-appeals-in-aca-marketplace-plans-in-2024/
Clinician Trust Drives AI Adoption, Not Accuracy Claims
99% accuracy sounds impressive. But belief happens when clinicians see it firsthand. Trust is the real implementation strategy. Full interview: https://t.co/YKdRTovquF @HealthCatalyst #clinicalimprovement #HITSM https://t.co/UpRxxGdPEK
Free Market Could Make Ozempic Affordable for Millions
The free market (no government-granted patent monopolies) will make Ozempic affordable for tens of millions of people https://t.co/SYl5M82mux
Radiologists and AI Struggle to Spot Deepfake Scans
The majority of radiologists and 4 LLMs were unable to differentiate synthetic, deepfake scans from real ones https://t.co/aAJhP0cpfG @RSNA https://t.co/q0wdIKicK6
AI Scribes Cut Docs' Work, Spark New Burnout Crisis
Ambient AI scribes are the biggest breakthrough in clinical documentation in a decade. They will absolutely cure the charting backlog. But they will introduce a much more dangerous form of physician burnout. Dr. Dike Drummond explains the incoming crisis. Right now, clinical...
Safeguarded AI Beats Physicians, Not Raw Models
The real way to use AI for medicine is to build safety, accuracy and triage on top of the big models like OpenAI. Using these models directly can be harmful. With appropriate safeguards Ai performs much better than the median...
Introducing a Noninvasive Test for Endothelial Function
I’m excited a new noninvasive way to evaluate endothelial function. Stay tuned for a deeper dive as I test it on myself. https://www.vendys2.com/drlufkin VENDYS_2
Health Tech Proves Resilient Amid SaaS Market Turmoil
Amidst the SaaS bloodbath fears, is health tech actually safer than people think? I sat down with @SeanDuffy (CEO of @OmadaHealth) and Stephanie Davis (Healthcare Industry Analyst) to dig into what's really happening in the markets and what it means for...
FDA Job Posting Omits Vaccine Requirement, Sparks Speculation
The Readout newsletter contained this nugget today. The posting for Vinay Prasad's job at #FDA states applicants don't need to be vaccinated. USG job postings don't normally address vaccination status. Message to the MAHA base? Sign up for @statnews newsletters here: https://t.co/Q3BKEkVZs0
Seven‑Domain Framework Elevates Person‑Centered Longevity Care
The Longevity Medicine Patient Experience Framework: A Seven-Domain Model for Optimizing Person-Centered Longevity Medicine "By operationalizing a patient-experienced, person-centered approach, this framework offers potential solutions to common challenges in longevity medicine, including care fragmentation, accessibility barriers, and poor patient engagement. It...
Digital Tech Redefines Pharma Manufacturing and Distribution
This book explains how disruptive technologies and emerging trends such as robotics, artificial intelligence, 3D printing, precision medicine or patient design will impact the manufacturing and distribution of pharmaceuticals in order to prepare successfully for a better future of healthcare. Everything...
Ibogaine Could Save Veterans, Despite U.S. Ban
Teared up watching In Waves and War last night. Every day ~20 vets commit suic*de. Heartbreaking. The doc showcases ibogaine’s massively positive benefits for three troubled navy seals. Unfortunately it’s illegal in the US but ketamine isn’t and has had similar...
New AD Combos Outpace Dupilumab, Injection Frequency Drops
Atopic dermatitis landscape from Wedbush. Looks like there are two parallel vectors: lower injection frequency ( $APGE ) and combining new mechanisms with IL13/IL4R. So far $JNJ's IL13+IL31 failed (the only one to be directly compared to dupi) while $PFE's...
Former Acorda CEO Joins Parkinson’s Cell Therapy Startup
How former Acorda CEO Ron Cohen landed at a Parkinson’s cell therapy startup https://t.co/93JYvJGM9I by @realJacobBell #biotech #startups
GLP‑1 Weight Loss Risks Muscle Loss without Proper Monitoring
We are prescribing powerful weight loss drugs without measuring the most important metric: muscle mass. Physical therapist Maureen McBeth has tested the body composition of countless patients who lost 50 pounds on GLP-1s. The results? Dangerously low skeletal muscle and exceptionally...
Inulin Cuts Knee OA Pain, Boosts Sensitivity and Strength
Effect of Prebiotic Supplementation With and Without Physiotherapy on Pain and Pain Sensitivity in People with Knee Osteoarthritis "Inulin and PSE each produced meaningful pain reductions. Only inulin improved pain sensitivity and grip strength, the latter paralleled by increased GLP-1, and...
Patented Chemo Reform Boosted Profits, Not Patient Benefits
Please. This is nonsense. You figured out a way to swap castor oil for albumin making it easier to administer paclitaxel, a standard chemotherapy. Same side effects. Look at the label. The best thing you did, for you, was secure...
P‑tau217 Predicts Dementia Risk with Combined Hormone Therapy
Blood levels of the Alzheimer's biomarker p-tau217 may help identify which women are more vulnerable to dementia when using combined hormone therapy after menopause, while estrogen-only therapy does not show the same association. menopause
Direct Immune Cell Injection Eradicates Multiple Mouse Cancers
A potentially game-changing discovery by @UCSF's Justin Eyquem @j_eyquem & colleagues – injecting cancer-fighting immune cells directly into the body kills several types of cancers in mice. Paper in @Nature: https://t.co/EXbsfx7whl Summary/video by UCSF: https://t.co/qLYXXvEDTV
Sony Debuts Versatile Surgical Robot Tested on Animals
#WhosNext? Surgeons? Sony recently unveiled their new Surgical Robot by having it slice and stitch a kernel of corn. It can also auto-switch between its different tools, and has successfully been tested in animal surgery. #Robotics...
Insurance Error Leads to $622 Bill Despite Appeal
My health insurance accidentally coded my annual physical incorrectly, and now I have a $622 bill, and they have rejected my appeal even though they know it's in error. What a wonderful healthcare system we have 😚
Vitamin K Shot Saves Newborn Lives—Don’t Skip It
Please give the vitamin K shot to your newborn. Their life (and yours) may just depend on it. pediatrician #newborn #parenting
Doctors Endorse Peptides as Effective and Favorable
Meanwhile: Anecdotal data: "I spoke lots of doctors, they all said peptides are great and they like them"
Minor Lifestyle Tweaks Cut Major Heart Risks
Even small differences in sleep, physical activity and nutrition (SPAN) can have significant favorable impact vs major adverse cardiovascular events @uk_biobank, >53,000 participants, median age 63 yrs https://t.co/iZJjENsOiM https://t.co/WNiGfGGDYL
Clinician Endorsement Drives Patient Adoption of Digital Health
I found a Digital Health tool in our patient portal early in my wife's pregnancy. Even though I knew what it was, even though I literally build Digital Health tools for a living - we did NOT use it. Why? Because...
Cardiologists Lag in Lifestyle Guideline Knowledge and Adherence
Cardiologists’ Knowledge and Compliance With Lifestyle Recommendations For CVD Prevention - American College of Cardiology https://t.co/bJr4ddGVHD #CardioTwitter #physicians #MedEd #cardiologists #health #lifestylemedicine
Delivery Bugs Revealed Zipline’s True Product‑market Fit
Keller Rinaudo Cliffton from Zipline thought making the drones would be the hardest part. It was only 15% of the problem. The company spent 9 months figuring out delivery for one hospital. Weeks of all-nighters. Building inventory software in a...
Brief 5‑MeO‑DMT Trip Yields Month‑Long Antidepressant Boost
One of the most remarkable things about 5-meo-DMT as an antidepressant is that the psychoactive experience is so brief. 10 minute peak, perhaps. 20 min total. And people seldom remember it well. Yet it has possibly the largest anti-depressant effect...
Cyborg Organoids Sense Glucose, Release Hormones for Diabetes
Bioengineers embedded soft, stretchable electronics into the tiny clusters to create “cyborg” organoids. These can mimic the pancreas, sensing glucose levels and releasing hormones. They could help build replacement cells for people with type 1 diabetes. https://spectrum.ieee.org/cyborg-stem-cell-therapy-for-diabetes