Omada Launches Cholesterol Program with Coaching and Specialist Support
Omada is between-visit care for real life. Now that care includes cholesterol management. More than 86 million Americans are living with high cholesterol. Our new program, Omada for Cholesterol, includes health coaching, peer support, and guidance from a clinical specialist trained to support people living with high cholesterol. https://t.co/ENOF9US1tI
Health as a Point, Disease as Trajectory in Latent Space
Latent Space as a Physiological Map: All our medical data, genomes, scans, notes are just different shadows of one underlying physiological state. Health = a point in high-dimensional space. Disease = a drifting trajectory Treatment = a vector,...
New Therapeutic Triad Accelerates Huntington's Disease Breakthroughs
“Huntington’s Disease and The Triad of Therapeutic Conviction”. Debut blog from Eric Green, CEO of Trace Neuro, explaining why and how advances are happening in HD. Genetics, cellular understanding, and enabling modalities. https://t.co/pAr9EQs5gJ
Prevention Profits only when the System Changes
The elephant in the room? Healthcare talks endlessly about prevention. But who, exactly, gets paid when you don’t get sick? Follow the incentives and the whole story changes. Until staying healthy becomes more profitable than treating disease, prevention will keep being marketed like a...
Hiring Dietitian Clueless About Anatomy Reveals Systemic Oversight
HOW does a hospital end up hiring a dietitian who “didn't know where intestines were”?! 😳 A sign of our times, perhaps? Tut-tut. Via @JHumphriesBBC @BBC https://t.co/PeXXIkdw0c
FDA Chief Outlines Agency’s Food Agenda to Congress
Amid the Trump administration's focus on food, a key FDA leader briefs lawmakers on the agency's plans https://t.co/SrXI4ObmGF
Hope for Compassionate, Competent EDs Like Pitt
Just over here longing for a world where every real ED could be more like the Pitt - Heartfelt humans - Competent care - No patients' needs dismissed
Consumer Preferences Unmapped Amid Low Family Medicine Pay
Has anyone mapped this into what consumers *want* and/or *value*? The sucky pay for family medicine is glaring; what about others? @HealthyThinker
Gleamer AI Outperforms Clinical Validation in Real-World Use
An AI delivering more in the messy real world, than on the (already outstanding) original clinical validation publication … that’s the power of @gleamer_ai , now part of @RadNetImaging DeepHealth 🚀 #radiology #AI @BIR_News 2026 London https://t.co/PhFjveXqWQ
AI Will Reshape Healthcare; Leaders Must Drive New Thinking
Everyone agrees AI will change healthcare, but institutional momentum hasn't shifted to redeploy people. The question isn't "who gets left behind?" It's: Who leads the thinking? https://t.co/AyFMFqXwyL
White House Drug Pricing Bill Details Revealed, Previewed by Insiders
Early details of what's in the White House's drug pricing bill text — and who's getting a sneak peek of it https://t.co/Yt8usm4yOa
GLP-1 Drugs: Brain‑targeted Cure for Obesity and Addictions
In 1992, scientists discovered a chemical in Gila monster venom that mimicked GLP-1, the hormone your gut releases to signal fullness. By tinkering with its structure, pharma companies extended its duration from two hours (the Gila monster version) to one...
Flexpa Powers the Emerging AI-Driven Healthcare System
.@flexpa is integral to enabling the AI-powered healthcare system currently being built. and we're ready for all of it.
Tennis Elbow Affects Everyone, Not Just Athletes
Why Does My Elbow Hurt So Much? Tennis elbow affects 1–3% of the population at any given time. Over a lifetime, virtually everyone will experience it. The vast majority of people who develop it have never played tennis. They are carpenters,...
Patients Use AI for Nonstop Medical Questions, Not Trust
Patients aren't turning to AI because they trust it more than their doctors. They're turning to it because their questions don't stop between appointments. First piece on Substack: https://t.co/OciXwTtxM1
AI in Revenue Cycle: High Hopes, Low Adoption
Healthcare wants AI in revenue cycle, but adoption is lagging. 67% have high hopes. Only 14% have implemented it. Why? Data quality and workflow trust. Insights from Experian Health + Integris Health 👇 https://t.co/SdtyNSwza6 @Experian_Health #IntegrisHealth #AIinRCM #HITSM
AstraZeneca's Lung Drug Scores Unexpected COPD Trial Win
AstraZeneca lung drug gets ‘surprise’ win in COPD trials https://t.co/QuRlOQtzdT @ByJonGardner $AZN $RGN $SNY $RHHBY
Legacy EHRs Can't Keep Pace with AI‑Native Competition
The SaaS-pocalypse playing out in public stocks reflects a real fear. Legacy SaaS companies, even with their existing distribution and install base, may be unsuccessful in bolting on AI capabilities to their legacy platforms. There is fear that their user...
Blood Test May Forecast Alzheimer’s Risk Decades Early
Could a simple blood test predict your risk of getting #Alzheimers dementia years, or even decades, before you experience memory loss? https://t.co/oLROODZbFz
Novartis Acquires Excellergy to Secure Xolair Successor
Novartis targets Xolair successor in buyout of startup Excellergy https://t.co/eGYQ2AxTd5 by @gwendolynawu $NVS $RHHBY #startups #biotech
Avoiding Sun May Double All‑Cause Mortality Risk
Is sun avoidance a risk factor for mortality?☀️ In this 2014 study from Sweden, sun avoidance was associated with nearly a 2x higher rate of all-cause mortality compared to the most active sun exposure habits. They did find increased risk of malignant...
UCLA Health Omits Patient Polygenic Risk Scores From Study
Kudos to @UCLAHealth for assessing genomics of their patient population, published @CellCellPress today. But why weren't the results of increased polygenic risk scores (PGS) provided to the patient participants? https://t.co/F15isJfDQy https://t.co/3AW7peHa1C
Aging Research Gains Momentum: Collaboration Fuels Therapeutic Breakthroughs
Now at 1M+ views. What struck me most here wasn’t the views. It was the engagement. People are ready to engage seriously with aging biology. Now the opportunity is to turn that energy into stronger collaboration, better translational science, and...
Women Still Underrepresented in GI, Impacting Patient Care
Half of U.S. med students are women. But some specialties still haven’t caught up. Heading to the Women in GI Conference in Atlanta where I’ll serve on the faculty. Honored to be in the minority. Representation isn’t just about fairness. It’s about better...
Measles Cases Surge to 1,575, 16 New Outbreaks
#Measles update: #CDC reports the confirmed case total this year to date is 1,575 — or 69% of the number of cases in the entirety of 2025. That's up 88 from last week. 94% of the cases are parts of...
AstraZeneca Honors Faerie Royalty in COPD Trial Names
Hats off to $AZN for naming its COPD trials after the king and queen of the faeries.
AI Boosts Care but May Raise Healthcare Costs
AI is providing both immense utility to clinicians, but will also drive up costs if the incentives in our current system stay the same. This may be correct billing, but it's also still MORE billing. https://t.co/jmcWQ3q3EK
In‑vivo CAR‑T Achieves 4/5 MRD‑Negative Remissions
Outstanding piece here from @leilei_wuu on AstraZeneca's in vivo CAR-T for multiple myeloma. There's data on 5 patients, which is pretty lean, but 4 come out MRD negative in two months, which is extraordinary. We're going to see a lot...
Tech Experts Overestimate Their Grasp of Cancer Biology
As someone who has covered cancer drug development for 25 years, one of the few things I am sure of is that the odds of technology folks thinking they understand biology are much higher than the odds they actually do.
Metabolic Disturbances Drive Multimorbidity, Offering Intervention Targets
Shared and specific blood biomarkers for multimorbidity "Metabolic disturbances emerged as a key driver of multimorbidity. If confirmed, these processes could represent targets for interventions to mitigate disease accumulation." https://t.co/3nuctP2eAC https://t.co/yxk5CZHiHV
NIH Foreign‑collab Restrictions Affect 25% of U.S. Scientists
Survey shows the NIH's restrictions on foreign research partnerships significantly impacted 1 in 4 U.S. scientists https://t.co/YVbTQ4tveG
FDA Commissioner Seeks Private Partnerships for Collaboration and Regulation
Couple interesting meetings for FDA Commissioner Makary: met with Arnold Ventures on Mar. 3 about "collaboration opportunities" https://t.co/vEyhDu5xaW and with $MNPR on "establishing a regulatory mechanism" on Mar. 13 https://t.co/DHaD6IlvCS
Questioning Rural Medicaid Inclusion in New Initiative
This is a great step and should be applauded. But is anyone on the list who lives in a rural area and qualifies for Medicaid? Love to suggest that for humble consideration.
Medical Training Ignores Self‑Care, Fuels Empathy Burnout
The heart oxygenates itself first. The first branches of the ascending aorta are the left and right coronary arteries. Yet the culture of medicine actively trains physicians to do the exact opposite. In a recent conversation on The Podcast by KevinMD, integrative...
Prescribe Exercise Before Drugs for Chronic Disease
As a medical school professor, I teach my students to prescribe drugs. But a landmark review in Cell Metabolism argues we should prescribe exercise first. Febbraio and Pedersen -- the scientists who coined "exercise as medicine" -- reviewed 233 studies on...
When You Eat Impacts Metabolism as Much As What
As a medical school professor, I was trained to focus on WHAT patients eat. But this massive meta-analysis says WHEN may be just as important. 41 randomized controlled trials. 2,287 participants. Published in BMJ Medicine. The finding: time-restricted eating improved nearly every...
Asia Emerges as Testbed for Healthcare Innovation
It was a pleasure to participate in the Investment and Innovation Pathways to a Healthy Asia session at the Global Investors’ Symposium in Hong Kong. A timely discussion on where durable value is being created in healthcare across Asia, from prevention...
MediClin Posts Modest 2025 Growth; Watch 2026 EBIT
MediClin: 2025 revenue +4.8% to €784.5m, EBIT +3.5%. Drivers: post‑acute growth, stable occupancy; acute fell after Heart Centre sale. Risk: narrow 2026 EBIT range. Buy, watch 2026 EBIT. — Viktor Kopylov, PhD, CFA. More insights: t.me/si14Kopylov
Alpha‑Lipoic Acid Shows Promise for Ischemic Heart Failure
Efficacy of Alpha-Lipoic Acid in Patients With Ischemic Heart Failure: A Double-Blind, Randomized, Placebo-Controlled Study | @JACCJournals https://t.co/nW9SbwEDfy https://t.co/qsemjmMb9k
GLP‑1 Therapies Show Promising Cardiovascular Benefits
GLP-1 and the cardiovascular system "This Review summarizes the effects of GLP-1 and GLP-1RAs in the CV system..." https://t.co/Sy7Jjb96WD https://t.co/v3T01fIcOs
Questioning Anti‑Tiering Clauses: Policy Recommendations Still Relevant
is there any rationale for allowing anti-tiering, anti steering, and "all or nothing" clauses in hospital contracts with insurers? Barring these was one of the centerpieces of our healthcare competition policy recommendations almost a decade ago https://t.co/8PPf8H5iMw
A Fresh Path for Young Physicians and Med Students
Sound and thoughtful advice from @DGlaucomflecken in my recent article on @BakerInstitute website (our policy think thank @RiceUniversity) I’ve proposed an alternative or parallel for young physicians and med students, it’s a bit out there and still half-baked https://t.co/0NN1omZTWk
Billionaires Fund Headless Human Clones for Organ Farms
Billionaire-backed scientists aim to grow 'headless humans' to farm their organs... and help biohackers live for longer https://t.co/uQOzEtBapf https://t.co/HYZCMCOPy3
Uric Acid Predicts Sex‑Specific Cognitive Decline in Seniors
Serum uric acid levels and longitudinal change in cognitive function in older adults: a sex-stratified population-based study https://t.co/vl5LLY6mBc
Public Health Needs Standardized Peptide Nomenclature Committee
Public health discourse needs a nomenclature committee before this “peptides” thing gets out of hand. So many types, so much variation in evidence, so much at stake. Common language would really help everyone: pro and against.
AI Automates Radiology Tasks, but Radiologists Still Thrive
On Lex Fridman's podcast this week, Jensen Huang brought up radiology and AI, highlighting radiology as an important data point for how we can expect AI to influence jobs. He talked about how nearly a decade ago, AI researchers predicted...
Navigating Myeloma MRD: When to Stop Treatment
MT @hhashmi87 #IMS25 Great Meet The Expert talk by @bdermanmd on MRD in Myeloma Risk vs benefit Who can stop treatment Active surveillance post discontinuation #mmMRD #mmsm https://t.co/Y1ti72KB2p
Lancet Calls for Wider Access to GLP‑1 Drugs
This week's @TheLancet cover and editorial about getting GLP-1 drugs available for the people who need them the most https://t.co/BU9NZdmdGo https://t.co/TWOIKvfuth
MRD‑Negative Patients Can Stop Myeloma Maintenance Therapy
Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP) - @bdermanmd et al. @ajjakubowiak #ASCO24 Abstract 106 https://t.co/FBTY7SnCxK #NCT04108624 #mmsm #mmMRD
ODAC Backs MRD Testing as Early Myeloma Trial Endpoint
A Historic Turning Point: ODAC Unanimously Votes [4/12/24] in Favor of MRD Testing as an Early Endpoint in Myeloma Clinical Trials to Support Accelerated Approvals of New Treatments [Apr 18, 2024] @IMFmyeloma https://t.co/eDOgIrpVeR #mmMRD #mmsm #ctsm @FDAOncology https://t.co/ejA8KSoxOL