Researchers Develop AI Framework Combining Expert Knowledge and Data to Accelerate Alloy Discovery
Researchers at Japan Advanced Institute of Science and Technology unveiled an AI‑for‑Science framework that merges experimental alloy data, computational models, and expert knowledge extracted from scientific literature using large language models. The system fuses these evidence streams with Dempster‑Shafer theory, explicitly quantifying uncertainty and allowing "cannot tell" outcomes when information is insufficient. Tested on high‑entropy alloy datasets, it achieved 86‑92% accuracy on compositions absent from training data and outperformed conventional machine‑learning and free‑energy methods. The approach also produces compositional maps that highlight reliable prediction zones and knowledge gaps.
Sarepta Plans FDA Run for Duchenne Exon Skippers Despite Confirmatory Trial Failure
Sarepta Therapeutics will submit a supplemental NDA to the FDA seeking to convert the accelerated approvals of its Duchenne exon‑skippers Amondys 45 and Vyondys 53 into traditional approvals, despite the confirmatory ESSENCE trial failing to improve motor function. The company bolsters its...
We Are EMBL: Aleena Mushtaq on Ensembl
Senior Ensembl Outreach Officer Aleña Mushtaq leverages her molecular biology background to deliver global training on the Ensembl genome browser. Ensembl, a free 26‑year‑old platform, integrates gene, variation and regulatory data, supporting projects like the Darwin Tree of Life. Mushtaq’s...
Scientists Are Using Tiny Pockets of Gas to Reveal the History of the Earth
Scientists have introduced a novel geochronology method that measures krypton gas trapped in zircon crystals to determine how long those minerals remained exposed at Earth’s surface before burial. The krypton forms when cosmic rays strike surface‑lying zircons, providing a “cosmic...
Generative AI Improves a Wireless Vision System that Sees Through Obstructions
MIT researchers have combined generative AI with millimeter‑wave (mmWave) radar to reconstruct hidden 3D objects and entire indoor scenes. The new Wave‑Former system fills gaps in partial reconstructions, boosting shape‑accuracy by roughly 20 % over prior methods. An expanded system called...
March 19, 1799: The Birth of William Rutter Dawes
William Rutter Dawes, born March 19, 1799 in London, transitioned from medicine and the clergy to become a leading 19th‑century amateur astronomer. From a private Lancashire observatory he catalogued over 200 double stars, later moving to George Bishop’s Observatory where...
Launch of Map to Report Asian Hornet Sightings
Jersey has launched an online map that allows residents to report Asian hornet sightings and nest locations. The platform includes a form, photo upload, and a live view of existing reports, helping the Biosecurity team verify and act quickly. Last...
Gossamer Nearly Halves Workforce in Savings Push After Late-Stage Hypertension Fail
Gossamer Bio announced a near‑half workforce reduction after its Phase 3 seralutinib trial failed to meet statistical significance in pulmonary arterial hypertension. The company will lay off 77 employees, about 48 % of staff, aiming to preserve cash while its future path...
Floating Wetlands Boost Water Quality, Slash Greenhouse Emissions
Researchers in Victoria, Australia installed a two‑tennis‑court‑sized floating wetland platform at the Westernport Water treatment lagoon. Over two years the plant‑covered platform lowered nitrogen concentrations by 12% and reduced total greenhouse‑gas emissions by 22%, with methane dropping after just four...
Gerd Faltings of Germany Wins 2026 Abel Prize in Mathematics
German mathematician Gerd Faltings has been awarded the 2026 Abel Prize for his landmark proof of the Mordell conjecture, now known as Faltings’ theorem. The Norwegian Academy of Science and Letters announced the honor, which carries a cash award of...
Comment | Climate Change Is Forcing Tough Choices—How Much Heritage Can We Save Before It Is Too Late?
Arctic permafrost thaw is accelerating the degradation of cultural sites, exemplified by South Aulatsivik 6 in Canada’s Nain archipelago. Researchers led by Rachel Labrie employed ground‑penetrating radar to identify the most vulnerable areas, offering a rapid, non‑invasive method for prioritizing excavations....
STAT+: Eli Lilly’s ‘Triple-G’ Drug Leads to Significant Blood Sugar, Weight Reductions in Diabetes Trial
Eli Lilly’s investigational injectable retatrutide achieved a 1.9‑point HbA1c reduction versus 0.8 points for placebo after 40 weeks, while participants on the highest dose shed 15.3% of body weight compared with 2.6% on placebo. The weight loss was still progressing at...
Will the EU Finally Make Waste Pay for Its Growing Carbon Footprint?
The European Commission must decide by the end of July whether to bring municipal waste incineration into the EU Emissions Trading System. Emissions from waste‑to‑energy plants have roughly doubled since 1990, releasing tens of millions of tonnes of CO₂ each...
Molecule in Python Blood Could Pave Way for New Obesity Drugs, Scientists Say
Scientists have isolated a gut‑bacterial metabolite, pTOS, that spikes in Burmese python blood after feeding and dramatically reduces appetite in obese mice. When administered to mice, pTOS caused a 9% body‑weight loss over 28 days without affecting energy expenditure. The...
Switching From Milk to Solid Food in Early Life Helps Reprogram the Gut's Immune Defenses, Researchers Find
Researchers at Baylor College of Medicine and Tongji University discovered that early weaning reshapes the gut microbiome, triggering epigenetic changes in intestinal stem cells that enhance immune defenses. The study, published in Nature Microbiology, shows loss of DNA methylation at...
Wondering How to Talk About Climate Change? Take a Lesson From Bad Bunny
Bad Bunny’s Super Bowl halftime stunt spotlighted Puerto Rico’s fragile, climate‑stressed power grid, showing how pop culture can convey climate urgency without a lecture. The performance reached over 100 million U.S. viewers, turning a visual spectacle into a de‑facto climate message....
ATLAS Sets Strong Limits on Supersymmetry
The ATLAS experiment at the Large Hadron Collider used advanced machine‑learning algorithms to probe supersymmetric particles in two new Run 2 analyses. One search focused on disappearing‑track signatures from chargino decays, while the other targeted low‑momentum leptons from neutralino cascades. Neither...
Thermochromic Bifacial PV Glazing System for Reducing Building Cooling Loads
Researchers at City University of Hong Kong have created a thermochromic bifacial photovoltaic (TC‑BiPV) glazing system that combines a hydrogel‑based thermochromic layer with bifacial solar cells. The hydrogel switches from transparent to translucent as temperature rises, reflecting light toward the...
You Don’t Need to Lose Weight to Reverse Prediabetes, Study Finds
A new Nature Medicine study shows that prediabetes can remit without any weight loss, challenging the long‑standing emphasis on shedding pounds to prevent diabetes. About 25% of participants in lifestyle programs normalized blood glucose despite stable weight, achieving protection comparable...
Possibility of Heightened Risk of Resistant TB Following Drug Treatment of Latent TB Owing to Lack of Confirmatory Tests to...
Latent tuberculosis infection (LTBI) affects millions, yet treatment relies on regimens without a gold‑standard test to confirm cure. Current diagnostics—tuberculin skin test and interferon‑gamma release assay— suffer false results and cannot differentiate active disease, leaving clinicians unable to monitor drug...
Metformin Reduces Weight Gain in Young People Taking Antipsychotics
A large pragmatic trial involving 1,565 overweight or obese youths with bipolar spectrum disorders found that adding metformin to a brief lifestyle program significantly blunted weight gain associated with second‑generation antipsychotics. Over six months, the metformin group’s BMI rose only...
Dawn’s Suborbital Spaceplane Completes Radar Tracking Experiment with Defence Science and Technology
New Zealand’s Defence Science and Technology agency and the Royal Navy teamed with Dawn Aerospace to conduct the DARTE radar‑tracking experiment, using the Aurora suborbital spaceplane off the Canterbury coast. The trial demonstrated that the frigate HMNZS Te Kaha’s surveillance radar can...
Could Fiber-Optic Cables Detect Moonquakes?
Los Alamos National Laboratory researchers propose using fiber‑optic cables as seismic sensors to detect moonquakes. The concept adapts telecom‑grade fiber, which can register minute strain changes, for deployment on the lunar surface. By embedding the cables in future lunar infrastructure,...
Autism Spectrum Disorder Across the Lifespan: Dynamic Symptom Trajectories and Multidimensional Support Framework
The Molecular Psychiatry review maps autism spectrum disorder (ASD) from childhood through old age, highlighting that symptom expression and functional challenges evolve across life stages. While pediatric ASD research dominates, the article underscores a stark evidence gap for adults and...
Mechanistic Insights Into Cannabidiol-Mediated TrkB Activation via FRS2 Interaction in Attenuating Alzheimer’s Disease Pathology and Cognitive Impairment
A recent preclinical study demonstrates that cannabidiol (CBD) directly engages the TrkB neurotrophin receptor through its PTB‑binding domain, recruiting the adaptor protein FRS2 to trigger robust downstream signaling. This activation attenuates amyloid‑β deposition, tau hyperphosphorylation, and neuroinflammation in transgenic Alzheimer’s...
RNA Modifications in Gene Regulation: Functions and Pathways
RNA epigenetics has expanded to over 170 chemically modified nucleotides that shape gene expression at transcriptional and post‑transcriptional levels. The review highlights m6A as the most studied mark, detailing its writer‑METTL3/14 complex, erasers FTO/ALKBH5, and diverse readers that control RNA...
Editorial Expression of Concern: A FADD-Dependent Innate Immune Mechanism in Mammalian Cells
Nature has issued an editorial expression of concern for the 2004 study linking FADD to innate antiviral immunity after detecting overlapping microscopy images across multiple figures. The flagged panels include Figure 1g, Figure 4a, Figure 4g, and supplemental Figures S1a and S2a, suggesting possible...
New DNA Base Editor Minimizes Bystander Edits While Maintaining High Efficiency
Researchers at UC San Diego have engineered a minimally evolved adenine base editor (ME‑ABE) that dramatically cuts bystander DNA edits while preserving the high on‑target efficiency of newer ABE8 variants. By reverting five specific mutations in the older ABE7.10 scaffold,...
Hong Kong: AI, Robotics Drive New Aerospace Technologies
A research partnership between Hong Kong’s Space Robotics and Energy Centre and Southeast University is accelerating autonomous space‑robotics, AI‑enabled navigation, and deep‑space energy management. The collaboration, supported by HKUST labs, targets rugged robotic platforms, precision manipulation, and modular power systems...
Global Insect Rescue Plan Requires New Technology to Ensure Success
A new study in Conservation Letters finds that the 23 biodiversity targets of the Global Biodiversity Framework could reverse insect declines if met, but current metrics lack insect‑specific sensitivity. Researchers highlight that only dragonflies and damselflies have been fully assessed...
India: Space Tech Drives Smart Agriculture and Disaster Resilience
India is harnessing space and digital technologies to boost agricultural productivity and disaster resilience. ISRO and the Department of Space have launched satellite‑based programs such as FASAL, NADAMS, CHAMAN and SUFALAM that deliver real‑time crop health, yield forecasts and drought...
The Comedy of Errors That Was the First-Ever Space Walk
On March 18, 1965, Soviet cosmonaut Alexei Leonov performed humanity’s first extravehicular activity, stepping outside the Voskhod 2 spacecraft for roughly ten minutes. The EVA quickly turned hazardous as his suit swelled, causing glove and boot failures and forcing him to...
Never Mind Band-Aids, Neanderthals Had Antiseptic Birch Tar
Researchers tested birch tar extracted using Neanderthal methods and found it inhibits Staphylococcus aureus, confirming its antiseptic potential. The study shows Neanderthals could have used birch tar for wound care as early as 200,000 years ago. Modern Indigenous practices align...
AI Software for Smart Glasses Wins £1m Prize for Technology to Help People with Dementia
CrossSense Ltd’s AI‑powered smart glasses, featuring the Wispy conversational assistant, have won the £1 million Longitude prize for dementia technology. The glasses combine a camera, microphone and speakers to deliver real‑time verbal cues and floating text that help wearers complete daily...
Pasqal and Kipu Quantum Demonstrate Analog Counterdiabatic Optimization on 100 Qubits
Pasqal and Kipu Quantum have experimentally realized Analog Counterdiabatic Quantum Computing (ACQC) on neutral‑atom platforms, scaling the protocol to 100 qubits to solve the Maximum Independent Set (MIS) problem. By analytically deriving counterdiabatic corrections for Rabi frequency, detuning and phase,...
New Real-World Evidence Supports the Use of AI in Lung Cancer Screening
A prospective trial of 911 asymptomatic patients undergoing low‑dose chest CT showed that AI‑assisted nodule detection modestly increased interpretation time by about 15 seconds but significantly boosted the identification of Lung‑RADS‑positive nodules. Radiologists using the AI tool reported roughly double...
Fluorescent Ruby-Like Gems Have Been Found on Mars for the First Time
NASA's Perseverance rover has identified tiny corundum crystals—ruby or sapphire‑like gems—inside a Martian pebble named Hampden River. The rover’s SuperCam instrument used dual‑laser spectroscopy and luminescence imaging to match the spectral signature of the grains to laboratory ruby standards. This...
Building Trust in the Future of Quantum Computing
Researchers at Japan Advanced Institute of Science and Technology (JAIST) have launched a formal‑methods program to make quantum computers trustworthy. Their Laboratory on Formal Methods for Quantum Computing has introduced Concurrent Dynamic Quantum Logic (CDQL), a framework that can model...
Why Doesn’t Astronomy Magazine Recognize Messier 110?
Astronomy magazine does not list Messier 110 because the original Messier catalogue, compiled by Charles Messier, stops at 103 objects. Although Messier observed the Andromeda satellite galaxy, he never assigned it a Messier number, and it was only added by amateur Kenneth Glyn Jones...
There Might Be Less Water on the Moon than We’d Hoped
A new study using NASA's ShadowCam on the Korea Pathfinder Lunar Orbiter finds that water ice in most of the moon’s permanently shadowed craters is limited to less than 20‑30 percent by weight, and many regions may have none at...
Boosting the Blood-Brain Barrier Could Avert Brain Damage in Athletes
Repeated head impacts in contact sports have been linked to lasting damage of the blood‑brain barrier (BBB), a finding that may underlie chronic traumatic encephalopathy (CTE). Researchers scanned 47 retired athletes using an MRI contrast agent that only enters brain...
NASA's Perseverance Mars Rover Discovers Even Older Lost Rivers at Jezero Crater
NASA’s Perseverance rover used its ground‑penetrating radar to probe deeper than before in Jezero Crater. The instrument identified buried river‑carved slopes and a delta more than 35 meters below the surface. Analysis of the radar echoes indicates these features formed around...
How Common Are Fireballs Streaking Across the Sky?
A 1.8‑meter, 7‑ton space rock streaked across the sky near Cleveland this week, dazzling observers from Wisconsin to Maryland before disintegrating after a 55‑kilometer atmospheric passage. The American Meteor Society notes that such fireballs—meteors brighter than Venus—are far from rare,...
“Whiplash”: Heart Attack and Stroke Risk Jumps When People Stop Taking GLP-1s
Researchers tracking 333,000 U.S. veterans with type 2 diabetes found that stopping GLP‑1 drugs sharply increases heart attack and stroke risk. A six‑month interruption raised cardiovascular events, and a two‑year gap elevated risk by up to 22 percent. Continuous use cut risk...
UBC Researchers Fight Tire Toxins Threatening Salmon
Researchers at UBC’s Scholes Lab have identified 6PPD‑quinone, a tire‑wear byproduct, as a lethal contaminant for coho salmon in Pacific Northwest streams. Through the interdisciplinary STREAM project they are modeling which waterways, especially those near highways and First Nations reserves,...
TerraPower Commits $450M to Build Radioisotope Production Plant
TerraPower Isotopes is committing $450 million to build a cGMP‑compliant actinium‑225 manufacturing plant in Philadelphia, a move that will expand production capacity roughly twenty‑fold. The 250,000‑square‑foot facility, slated to begin output in 2029, will create 225 full‑time jobs and benefits from...
This Overlooked Organ May Be More Vital for Longevity than Scientists Realized
New AI‑driven analyses of thousands of CT scans reveal that thymus health strongly correlates with longevity, cardiovascular disease risk, and lung cancer incidence. The studies show individuals with a robust, non‑involuted thymus live longer and experience fewer major health events....
Astronomers Search for 'Exotrojans' Hiding in Extreme Pulsar Systems
Astronomers led by Jackson Taylor have applied novel timing techniques to search for co‑orbital “exotrojans” in nine black‑widow pulsar binaries, including an optical‑to‑radio comparison for PSR J1641+8049 and a 15‑year NANOGrav radio‑pulse analysis of eight others. The study found no definitive...
A Static Electricity Mystery Comes to the Surface
Scientists have discovered that a thin carbon‑rich film on silica surfaces governs how identical insulating particles exchange static charge. Using acoustic levitation, they showed that heating or plasma treatment removes this layer, flipping the charge polarity between a silica sphere...
STAT+: Clearing Tumors in Mice, Azalea Therapeutics Advances Dream of in Vivo CAR-T Therapy
Azalea Therapeutics, a spinout from Jennifer Doudna’s lab, reported in Nature that its in vivo CAR‑T approach can generate functional CAR‑T cells directly within mice and eradicate both solid and hematologic tumors. The technique uses infused gene‑editing particles that precisely...