NeuroScientific Readies Stem Cell Supply Boost for Bowel Disease Trials
NeuroScientific Biopharmaceuticals has begun its first manufacturing run of the StemSmart mesenchymal stem cell therapy at Q‑Gen Cell Therapeutics in Brisbane, initiating a critical technology transfer. The engineering run will validate quality, potency and regulatory compliance ahead of a Phase 2 trial for fistulising Crohn’s disease. Early Special Access Program data showed three of four patients achieved clinical response. Full transfer is expected by the second half of 2026, positioning the company to tap the projected $13.8 billion Crohn’s therapeutics market.
Molecular Basis of Oocyte Cytoplasmic Lattice Assembly
A Nature paper published March 17, 2026 presents the first cryo‑electron microscopy structure of the mammalian oocyte cytoplasmic lattice (CPL). The study identifies fourteen constitutive protein subunits and describes a repeating architecture built from U‑shaped basket (UB) and adapter ring...
Organization of Neuropeptide Systems in the Human Brain
Researchers built a whole‑brain atlas of 38 neuropeptide‑receptor genes, mapping their expression across 455 cortical, subcortical and hypothalamic regions. The receptors display a clear cortical‑subcortical gradient and two principal axes within hypothalamic nuclei that reflect developmental organization. Spatial overlap analysis...
Planar Li Deposition and Dissolution Enable Practical Anode-Free Pouch Cells
Researchers at Westlake University have demonstrated an anode‑free lithium‑metal pouch cell that reaches 508 Wh kg⁻¹ energy density by using a crossover‑coupled electrolyte. The electrolyte creates a boron‑fluorine polymer‑rich solid‑electrolyte interphase (SEI) that is sub‑nanometer homogeneous, flexible, and enables uniform planar lithium...
Triple-Junction Solar Cells with Improved Carrier and Photon Management
Researchers have demonstrated a perovskite‑perovskite‑silicon triple‑junction solar cell that reaches a certified 30.02 % power conversion efficiency on a 1 cm² substrate. The breakthrough combines a non‑volatile additive, 4‑hydroxybenzylamine, which aligns crystal growth and suppresses non‑radiative recombination in the wide‑bandgap top cell,...
China Space Station Spacewalk: New Tasks Completed
China’s Shenzhou‑21 crew completed a second seven‑hour EVA, installing a new space‑debris protection device on the Tiangong station. Astronauts Zhang Lu and Wu Fei performed the walk with assistance from the station’s robotic arm and fellow crew member Zhang Hongzhan. The mission also...
Reduced Physical Activity Due to Global Heating Will Lead to Rise in Health Issues, Study Says
A new Lancet Global Health study links rising temperatures to a measurable decline in physical activity worldwide. Each additional month with average temperatures above 27.8 °C raises inactivity by 1.5 percentage points globally, and 1.85 points in low‑ and middle‑income nations. By...
No Evidence to Suggest Medicinal Cannabis Is Effective for Depression, Anxiety or PTSD, Says Systematic Review
A systematic review published in Lancet Psychiatry, analysing 54 randomized controlled trials from 1980‑2025, found no evidence that medicinal cannabis treats depression, anxiety or PTSD. The paper highlights modest benefits for conditions such as epilepsy, multiple sclerosis spasticity, pain and...
Common Pesticide May More than Double Parkinson’s Disease Risk
A UCLA Health study links long‑term residential exposure to the pesticide chlorpyrifos with a more than 2.5‑fold increase in Parkinson's disease risk. Researchers analyzed 829 Parkinson's patients and 824 controls, estimating exposure through California pesticide records, and corroborated findings with...
Taking a Look at the Spring Forecast
The latest seasonal outlooks for Canada’s Prairies show a patchwork of temperature and precipitation signals across March‑May. While the Old Farmer’s Almanac and NOAA suggest near‑average warmth and rain, the CFS model leans toward a warm end‑March, cooler April, and...
Light-Controlled Hydrogel Mimics Soft Human Tissue for More Realistic Cell Studies
Researchers at the University of Colorado Boulder have created a light‑controlled hydrogel that closely replicates the softness and viscoelastic behavior of human tissue. The material can be solidified or softened on demand using photopolymerization, allowing precise spatial control during 3‑D...
Frog-Cell 'Neurobots' Grow Self-Organized Nervous Systems and Alter Gene Activity
Researchers at the Wyss Institute have created the first “neurobots,” living robots built from frog embryonic cells that incorporate neuronal precursor cells to form self‑organizing nervous systems. The neurobots develop mature neurons that connect internally and extend processes to surface...
Europe’s Spectrum Rocket Returns to the Skies with Onward and Upward
German startup Isar Aerospace is set for the second flight of its Spectrum launch vehicle, dubbed “Onward and Upward,” from Andøya Space in Norway on March 19. The mission marks the rocket’s first customer payload flight, carrying five CubeSats and a...
CARPOOL Radial Access as Good as Femoral in PAD Procedures
The CARPOOL observational study compared radial‑to‑peripheral (R2P) and femoral access for peripheral artery disease (PAD) interventions and found comparable 30‑day major adverse limb event (MALE) rates. While radial access achieved a technical success of 87.2% versus 94.9% for femoral, it...
Millions of Protein Complexes Added to AlphaFold Database Shed Light on How Proteins Interact
A joint effort by EMBL‑EBI, Google DeepMind, NVIDIA and Seoul National University has added millions of AI‑predicted protein complex structures to the AlphaFold Database, marking the largest collection of such data to date. The release focuses on high‑confidence homodimers, delivering...
Illumina Launches Software for Multiomic Analysis
Illumina unveiled Illumina Connected Multiomics, a cloud‑based platform that unifies single‑cell, spatial transcriptomics, proteomics, and methylation data for large‑scale analysis. The system aggregates thousands of samples from Illumina and third‑party assays, delivering reproducible results through DRAGEN secondary analysis. AI‑driven tools...
Stress May Augment Impact of Adverse Pregnancy Outcomes on CV Health
Researchers found that women who experienced an adverse pregnancy outcome (APO) and reported high psychosocial stress had significantly higher diastolic blood pressure 2–7 years postpartum, whereas stress alone did not affect blood pressure in uncomplicated pregnancies. The analysis of 3,322...
4D Printing Technology Uses Waste Sulfur to Enable Self-Actuating Soft Robots
Researchers at KRICT, Hanyang University and Sejong University have unveiled the world’s first 4D‑printing platform that uses sulfur‑rich polymers derived from petroleum‑refining waste. By engineering a loosely cross‑linked sulfur polymer network, the material can be extruded, printed, and programmed to...
Scientists Think Our Brains Might Use a Secret Pathway to Create Consciousness
A new review in *Biophysics and Molecular Biology* proposes a third neural signaling pathway called the biofield, where ultra‑weak photons (biophotons) emitted by neurons could convey information. The authors argue that biophotons possess quantum properties such as superposition and entanglement,...
Sound of Fear: A Direct Brain Shortcut for “Scary” Noises
Researchers identified a direct subcortical auditory pathway from the inferior colliculus and medial geniculate body to the basolateral amygdala, providing a “low‑road” route for rapid fear processing. Using diffusion‑weighted tractography on Human Connectome Project participants, higher fiber density in this...
Ultrasound-Activated Nanoparticles Breach Bacterial Biofilms
Scientists have engineered silica‑based nanoparticles that encapsulate rifampicin and release it only when exposed to low‑frequency ultrasound. The ultrasound both propels the particles through the protective matrix of bacterial biofilms and triggers cavitation that opens the particles, delivering the antibiotic...
AI and Genomics: A New Era of Personalized Medicine
Artificial intelligence is reshaping genomics by speeding up sequencing and uncovering patterns that traditional tools miss, enabling truly personalized medicine. AI models can predict disease risk, suggest optimal therapies, and guide tumor classification, especially in oncology and emerging mRNA vaccine...
The Awake “Sleep” Loop: Why Attention Lapses Occur in ADHD
New research published in the Journal of Neuroscience shows that adults with ADHD experience far more frequent "local sleep" intrusions—brief, sleep‑like slow waves that appear in isolated brain regions while awake—than neurotypical peers. Using EEG recordings from 32 medication‑withdrawn ADHD...
Smartwatch Data Can Be Used to Assess Early Diabetes Risk
Researchers at Google used AI to analyze smartwatch data from 1,165 users, combining heart‑rate, sleep and activity metrics with routine lab results to detect insulin resistance. The model identified the condition with 76% accuracy using only clinical data, rising to...
Fermilab’s PIP-II Accelerator Project Recognized at UK-US Research Showcase
Fermilab’s Proton Improvement Plan‑II (PIP‑II) accelerator was honored at the inaugural UK‑US Global Research and Innovation Impact Showcase, receiving the Pioneering UK‑US Breakthroughs Award for its superconducting radio‑frequency cryomodules. The recognition highlights a multinational effort, with contributions from the United...
The 48-Hour Oatmeal Diet That Could Improve Heart Health by 10%
A two‑day oatmeal‑only diet cut LDL cholesterol by 10% in a German clinical trial. The 48‑hour regimen, providing 300 g of oats three times daily, also produced an average two‑kilogram weight loss and slight blood‑pressure reductions. Remarkably, these improvements remained evident...
Nagoya University and NU-Rei Report First Gallium Oxide Thin-Film Epi Growth on Silicon
Researchers at Nagoya University and spin‑out NU‑Rei announced the world’s first heteroepitaxial growth of gallium oxide (Ga₂O₃) thin films on silicon wafers. The breakthrough relies on a High‑Density Oxygen Radical Source that doubles atomic‑oxygen density, enabling high‑speed homoepitaxial growth at...
Structure Therapeutics Inc. (GPCR) Discusses Positive Topline Results From ACCESS II and Related Studies of Aleniglipron Oral GLP-1 Transcript
Structure Therapeutics announced positive topline data from its ACCESS II trial of aleniglipron, an oral small‑molecule GLP‑1 receptor agonist. The study demonstrated statistically significant reductions in HbA1c and weight loss comparable to injectable GLP‑1 therapies. Safety signals were mild, with few...
Acetylcholine Seizes Control of Serotonin Signaling
Researchers discovered that striatal cholinergic interneurons directly trigger serotonin release via nicotinic receptors, showing acetylcholine can seize control of serotonin signaling. Optogenetic activation produced an instantaneous 5‑HT surge, and hyperactive cholinergic cells in an OCD mouse model amplified this effect....
Forget the Multiverse. In the Pluriverse, We Create Reality Together
The article introduces the "pluriverse" concept, arguing that reality emerges from interlocking subjective perspectives rather than an objective, detached view. It claims this relational framework can dissolve longstanding quantum paradoxes by placing observers at the core of the cosmos. The...
The Asteroid Ryugu Has All of the Main Ingredients for Life
Japan’s Hayabusa2 spacecraft retrieved Ryugu asteroid samples in 2020 after impacting the surface in 2018. Laboratory analysis has now identified all five nucleobase precursors needed for DNA and RNA within the debris. The discovery strengthens the hypothesis that asteroids delivered...
Industrial Chemicals Have Reached the Middle of the Oceans, New Study Shows
A global study of 2,315 seawater samples, using untargeted mass‑spectrometry, found human‑made chemicals everywhere—from coastal estuaries to the open Pacific. Researchers detected pharmaceuticals, illicit drugs, pesticides and plastic‑derived compounds, some accounting for up to 20% of dissolved organic matter near...
Inside Sir Peter Beck and Rocket Lab’s Sub-$17 Million Mission to Find Life Above Venus
Rocket Lab’s Venus Life Finder (VLF) mission aims to drop a sub‑kilogram probe into the clouds of Venus for a brief 210‑second sampling window, targeting possible biosignatures. The entire venture is slated to cost under $17 million, dramatically cheaper than historic...
This Hidden Immune Signal Could Change Cancer Therapy
Researchers have identified that a surface‑defensive molecule on cancer cells not only sends a “don’t‑eat‑me” signal but also conceals an “eat‑me” cue that would normally trigger immune clearance. A newly engineered antibody can disrupt this masking interaction, making tumors visible...
Artemis II Crew ‘Primed’ to Contribute to Scientific Knowledge of Moon, NASA Scientist Says
NASA's Artemis II mission, slated for early April, will send four astronauts on a ten‑day lunar flyby, becoming the first humans to view the Moon’s far side since Apollo. The crew will operate within 6,400‑9,000 km of the surface, capturing wide‑angle imagery,...
Why Global Warming Is Accelerating and What It Means for the Future
Over the past three years, global temperatures have risen faster than most climate models predicted, confirming a consensus that warming is accelerating. Some researchers argue the surge reflects systematic model underestimation, while others attribute it to short‑term natural variability that...
Computational Model Predicts Telomere Length From Routine Biopsy Slide Images
Researchers at Sanford Burnham Prebys unveiled TLPath, a machine‑learning model that infers telomere length from routine histopathology slides. The system was trained on 5,263 whole‑slide images covering 18 organs from 919 individuals and can predict telomere shortening in 11 tissue...
As AI Keeps Improving, Mathematicians Struggle to Foretell Their Own Future
The First Proof initiative, a benchmark for large language models in research‑level mathematics, has launched its second round, mandating full transparency from participating AI firms. In the inaugural test, OpenAI and Google DeepMind’s models collectively solved about eight of ten...
Boffins Hook Fly Brain Map to Virtual Body, Which Starts Looking for Sugar
San Francisco startup Eon Systems announced the first digital simulation of a fruit‑fly brain that can drive a virtual body and produce recognizable behaviors. The model integrates the Flywire whole‑brain connectome—125,000 neurons and 50 million synapses—from an adult female Drosophila, runs...
Biomarker Assessments Reveal Global Vitamin B2 Deficiencies in Women and Children
A multi‑country study of 3,567 participants found riboflavin (vitamin B2) deficiency to be widespread, especially among women and children. Using the erythrocyte glutathione reductase activation coefficient (EGRac) assay, researchers documented deficiency rates of 45%‑90% in high‑ and low‑income nations. In Ireland...
Dutch Startup Plans Roll-to-Roll Factory for Perovskite Solar Cells
Dutch research institute TNO has spun off Perovion Technologies to industrialise lightweight, flexible perovskite solar cells. The company aims to construct the first roll‑to‑roll perovskite manufacturing line in the Netherlands by 2030, targeting applications where glass panels are impractical. A...
L3Harris Honors Goddard Centennial with Advances in Nuclear and Electric Propulsion
L3Harris Technologies commemorated Robert Goddard’s 100‑year rocket milestone by accelerating next‑generation propulsion, including 3D‑printed RS‑25 engines, advanced electric thrusters, and nuclear thermal concepts. The company is hot‑fire testing new RS‑25 units that cut production costs by 30 percent while delivering...
Ciemat Unveils Large-Area Multispectral Solar Simulator for PV Module Testing
CIEMAT has launched a large‑area multispectral solar simulator designed for precise electrical characterization of full‑size photovoltaic modules. The system delivers better than 0.4% spatial irradiance uniformity, 500 ms LED illumination pulses and dynamic I‑V acquisition, enabling single‑pulse testing of high‑capacitance modules....
The Math That Explains Why Bell Curves Are Everywhere
The central limit theorem (CLT) explains why bell‑shaped normal distributions appear in everything from rainfall measurements to SAT scores. Originating with Abraham de Moivre’s 18th‑century gambling calculations, the theorem was formalized by Pierre‑Simon Laplace and now underpins modern statistical inference. By...
LHCb Collaboration Discovers New Proton-Like Particle
The LHCb Collaboration announced the observation of a new baryon made of two charm quarks and one down quark, a particle whose mass is about four times that of a proton. The discovery, presented at the Moriond conference, achieved a...
March 16, 1485: A Solar Eclipse over England
On March 16, 1485 a solar eclipse traced a path from the Pacific across the Atlantic, where it lingered for a maximum of 4 minutes 53 seconds, before moving into Eastern Europe. England experienced only a partial obscuration, but the event coincided with the death...
Elevara Begins Phase 2b Trial of ELV001 in Rheumatoid Arthritis
Elevara Medicines has dosed the first patient in its phase 2b START‑SYNERGY trial, testing the oral CDK4/6 inhibitor ELV001 in rheumatoid arthritis patients who have failed methotrexate and TNF inhibitors. The randomized, placebo‑controlled study will enroll about 180 participants across nine...
Photonics and Nanotech Could Spot Cancer Signals 5 to 8 Years Earlier
Researchers at the University of Illinois Urbana‑Champaign have engineered a photonic‑nanomaterial platform that senses microRNA and DNA signatures linked to cancer up to five to eight years before conventional diagnostics can. The system leverages photonic crystal grating resonance and nano‑assemblies...
Researchers Identify Low Clinician Response to Elevated Lp(a) Levels
A multicenter retrospective cohort of nearly 15,000 low‑risk adults showed that 80% of patients with Lipoprotein(a) above 50 mg/dL did not start any lipid‑lowering medication within 90 days of testing. Initiation of statins was modest, while use of PCSK9 inhibitors and...
China Startup CirCode Gets Clearance for Trial of Circular RNA Therapy
Cir‑Code Bio‑med, a Chinese biotech focused on circular RNA medicines, has secured an Investigational New Drug (IND) approval from the U.S. Food and Drug Administration to commence its first human trial. The therapy targets a rare genetic disorder using a...