Alzheimer’s Begins in Your 30s, Not Just Old Age
I’m a doctoral researcher studying aging, and I wish more people realised this: Alzheimer’s isn’t a disease of old age. It often begins developing decades earlier — as early as your 30s and 40s — and only manifests later in life.
Leaving Massive Thermodynamic Computing for Cozy NISQ Quantum Systems
As we enter a new month, I'm leaving thermodynamic computing and going back to quantum computing. The fact that thermo systems will reach 100M+ pbits in scale within a year is too overwhelming to think about, I miss the coziness of...
Receipt BPA Slashes Teen Testosterone by Half
I don't wanna say but I told you guys Touching receipts -> BPA enters your bloodstream High BPA levels in adolescents -> 50% reduction in Testosterone levels
Aging Immune System Shapes Allergy and Biologic Response
Immunosenescence and Allergy: Molecular and Cellular Links Between Inflammaging, Neuro-Immune Aging, and Response to Biologic Therapies https://t.co/DMVxerI64T https://t.co/TUPGK6SqUK
Roscosmos Confirms Post‑ISS Station Built From New ISS Modules
Speaking at the Federation Council, Roskosmos chief also confirmed that the post-ISS station would be assembled at ISS out of (New) Node, Science & Power and Airlock modules (as I illustrated back in 2021 ;) Context: https://t.co/wVxTkUEbNa https://t.co/zOHPUfG7hC
Artemis II Launch Sparks Excitement for Moon Return
If you're looking for a reason to get psyched about the Artemis II launch today, check this out: https://t.co/qlqzQNJzby https://t.co/hbJQThOk2Q
Evolving Dark Energy Claims Remain Weak, Puzzles Persist
The flimsy case for evolving dark energy There's been a lot of talk about evolving dark energy, and how DESI data demands it. But the case for this remains somewhat weak, while the true underlying puzzles remain unsolved. https://t.co/Xh1dgGu3kI
Roscosmos Confirms First Methane‑Oxygen Engine Test Fired
According to Roskosmos chief, the "first firing of the methane-oxygen engine (presumably the RD-0177M demonstrator) took place just last week" (which would make it between March 23 and 29). Context: https://t.co/RwOb1eWwT3 https://t.co/lZc1VCXbeJ
Visceral Fat Loss Preserves Brain Volume and Cognition
This study on visceral fat loss blew my mind... It found that sustained visceral fat reduction over years was linked to preserved brain volume and cognitive function in middle age. They tracked people for up to 16 years, and those who lost...
Moonbound Tonight: Repeating the Dream Feels Better
People are going to the Moon (well, almost) again tonight. Saying it five times in a row, and each time feels a little better.
New Transcriptome Browser Streamlines BLAST DB Creation
Another feature adding to my terminal plasmid editor is a transcriptome browser. Helps you quickly build blast databases from a heap of transcripts in a single fasta file. Gonna add HMM/Pfam detection and Pfam search. I really love this current...
NASA Shares Live Artemis II Updates Alongside Livestream
In addition to the livestream, NASA is also posting live Artemis II updates here: https://t.co/9gcpALfGtC
Moon Mission Could Help Humanity Rediscover Earth
Science is transcendent -- true to nature in another galaxy on other side of the observable Universe. Humanity could use some of that transcendence here on Earth...by leaving Earth to go to the Moon. "58 Years After ‘Earthrise,’ NASA’s New...
Astaxanthin: 100× Stronger Antioxidant Boosts Health
Astaxanthin is a major antioxidant that's 100x more potent than vitamin E and vitamin C - protects skin against UV damage - lowers inflammation and neuroinflammation - lowers lipids and blood pressure - protects against oxidation of fats - protects the eyes - senolytic properties - lowers...
Why Replication Studies Remain Unpredictably Challenging
I wrote today about a big study on replication--and why it's so hard to know if a study will hold up or not. Gift link: https://nyti.ms/4sNu3MF
Choosing Aging Over Longevity Highlights Pathology, Not Greed
One reason I dislike saying healthspan or lifespan & prefer aging as label for the field over longevity. Aging puts focus on its terrible consequences/pathology. It makes the field defensive like medicine not greedy as some see wanting more life...
Artemis II Fueling Progresses Smoothly, Sparking Cautious Optimism
Excited to see that the Artemis II fueling is going so well, but can't but feel ... https://t.co/gJGnTj2Cc7
Artemis Repeats Apollo’s Uneconomic, Bureaucratic Moon Missteps
I'm genuinely excited to see America headed back to the Moon. But Artemis is a moondoggle and shows we haven't learned the deepest lessons of the Apollo era. Remember that Apollo did *not* result in durable progress in space. It marked...
Slow‑wave Sleep Flushes Brain’s Metabolic Waste
How Slow Waves During Sleep Take Over to Clear Metabolic Trash - https://t.co/JnnaGFUeMo via @neurosciencenew #sleep #MedTwitter #CardioTwitter #BrainHealth #dementia #lifestylemedicine #HealthyLivingCommunity #HealthyLifestyle #pavingwellness #health #mentalhealth
Stress Directly Triggers Addiction, New Study Shows
Direct Link Between Stress and Addiction Found - https://t.co/rwLwvh4egR via @neurosciencenew #Addiction #mentalhealth #alcohol #substanceusedisorder #health #lifestylemedicine #pavingwellness #HealthyLivingCommunity #WellnessJourney
Artemis Astronauts Brave Unproven Systems on Moon Mission
Imagine the sheer courage of today's Artemis astronauts: testing aspects of the Orion capsule, a new and more distant orbit around the moon, a heat shield that previously disappointed, and...worst of all...an as yet untested. . . um. . ....
First Woman Launches to Moon Today – Watch Live
The first woman in history is flying to the Moon today. 💅🏼🚀💕 The launch window opens at 6:24 pm EST. Watch live on nasa.gov
Only One Nation Has Landed Humans on the Moon
Not to throw my adorable and clever students under the bus, but I asked a group of over 30 college students how many countries have put a human on the Moon. Not one student knew for sure, but most suspected...
Positive Game Review Boosts Hormones, Performance; Negative Harms
Research on professional rugby players found that watching what they did wrong after a game led to elevated cortisol and worse performance the next game. Watching what they did well had the opposite effect, a bump in testosterone and better...
ER Binding Sites in MCF7 Cells Span 1,000–20,000
If I told you the answer to “How many ER binding sites are in MCF7 cells?” is anywhere between 1,000 and 20,000—would you believe me?
Artemis II Fueling Begins at Kennedy, Launch Day Overview
Fueling has started at Kennedy Space Center. Here’s a rundown of all the big events for Artemis II launch day. https://t.co/avBdoxvMmi
Metabolically Healthy Obese Children Still Develop Diabetes
As a medical school professor, I've seen textbooks call it "metabolically healthy obesity." A new study proves that label is dangerously misleading. Karolinska Institute tracked 7,275 children with obesity until age 30. The results in JAMA Pediatrics are staggering: -> 9% of "metabolically...
Quantum Computers Require Far Fewer Resources to Crack Encryption
Quantum computers need vastly fewer resources than thought to break vital encryption - Ars Technica https://t.co/pLuvHMFLOP
Metformin Undermines Exercise’s Insulin‑Sensitivity Gains
As a medical school professor, I've recommended metformin to countless patients. But a new double-blind trial just revealed something alarming. Metformin BLUNTED the insulin-sensitizing benefits of exercise in adults at risk for metabolic syndrome. The findings from a 16-week RCT: -> Exercise +...
Artemis II Launch Begins: Four Astronauts Head to Moon
It’s a beautiful morning in Florida. We will be watching closely as they fuel up the space launch system. The Artemis two mission will carry four people to the moon. It’s a moment in history and I’ll keep you posted.#milesobrien...
First Extraterrestrial Contact: Aliens Seek Trade, Humans Have Chance
Breakthrough News: Over the past 12 months we were working in secret on a clandestine project - the foundation model for search for and communication with Extracellular Life. Today, we managed to establish our first contact. The aliens want to engage...
NASA Greenlights SLS Fueling for Artemis 2 Launch
NASA says it is go to begin tanking the SLS for today's Artemis 2 launch attempt. https://t.co/wfaqCkBpTO
Europe Braces for Volatile Spring: Cold, Storms, Snow
Europe faces weeks of volatile spring weather, with competing atmospheric factors raising the risk of cold spells, storms and late-season snow. https://t.co/FlIR2N8BkT
FDA Grants RMAT Status to Caribou’s Anti‑BCMA CAR‑T Therapy
1/🚨@CaribouBio announced that the U.S. FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation to CB-011 - $CRBU allogeneic anti-BCMA CAR-T Cell Therapy for treating relapsed or refractory multiple myeloma (r/r MM) cancer which is being evaluated in the CaMMouflage...
DMTS-NC Boosts Neural MD Speed 3‑5
New group preprint: "Faster Molecular Dynamics with Neural Network Potentials via Distilled Multiple Time-Stepping and Non-Conservative Forces”, which introduces the DMTS-NC approach - a strategy designed to further accelerate atomistic molecular dynamics simulations using foundation neural network models. https://t.co/SIbycvoca7 Significant Speedups: using...
AI‑controlled Satellite Mirrors Will Deliver On‑demand Sunlight
You will soon be able to order sunlight the way you order a ride. That is not a metaphor. Reflect Orbital is building small satellites with deployable mirrors that can redirect sunlight to a specific area on Earth, on demand. What stands...
Speed Persists—Or Grows—During Detraining, Strength Declines
Building on data in untrained subjects, this study in trained athletes found that speed is not lost during detraining and may even increase. In this way, it contrasts with strength, which is lost. https://t.co/4fiSlHL1UJ
Obesity‑Gut Microbiota Drive
Neuroinflammation in Alzheimer's Disease: The Role of Obesity, Gut Microbiota, and Therapeutic Potential of Omega-3 Fatty Acids and Neural Stem Cells https://t.co/IB7nxSSupQ https://t.co/YSLYmsInF2
Artemis Costs Under 0.5% of US Budget
Alright, the Artemis II launch is less than a day away. So I want to address some recurring criticisms I've seen: it's too expensive, we need to solve problems down here, it's too dangerous, it does nothing for the greater...
Only Five of the 24 Lunar Pioneers Remain Alive
Between 1968 and 1972, twenty-four humans entered lunar space, where the Moon's gravity dominates that of the Earth (within about 66000 km from the selenocenter). Only five of them are still alive.
Adiponectin: Key Protector Against Age‑Related Decline
Adiponectin and aging: Mechanistic insights, clinical paradox, and therapeutic horizons "Adiponectin has been implicated in aging and the onset of age-related disease.... Adiponectin signaling protects multiple tissues from age-associated decline... Adiponectin signaling agonists as therapeutics in metabolic and age-related disease." https://t.co/9NcjtjlbjR
Skipping Power Training Increases Death Risk Sixfold
What’s more dangerous than doing power work? Not doing it. A 2025 study of 3,889 people found those with the lowest muscle power had a nearly 6x higher risk of death than the highest group. Slow training builds slow people. Slow people die...
Study's COVID Vaccine Benefits Limited to Early Pandemic
This tweet and accompanying paper are fairly misleading (note: paper is from July ‘24) There are many issues w the study itself that it’s a bit tough to go into here. But most importantly, the paper concludes: “Our findings support the...
Implantable Islet Cells Offer Injection-Free Diabetes Control
Implantable islet cells could control diabetes without insulin injections by Anne Trafton @MIT Learn more: https://t.co/aPCxukXMW1 #MedTech #HealthTech #Tech #TechForGood https://t.co/hXbxvs5HTM
Excited for Artemis Launch, Uneasy About April Fool's Timing
I am so unbelievably excited for this Artemis launch but I really REALLY wish they weren’t doing it on April fools day… the conspiracies have already started
Wishing NASA Success on Artemis Launch, Bon Voyage Christina
Wishing @NASAAdmin and the entire @NASA team the best for tomorrow's Artemis launch attempt - and a special 'bon voyage' to @centerforastro alum @Astro_Christina !
Plastic Chemicals Linked to Millions of Preterm Births
This is not good. “Everywhere chemicals” leaching from plastics may have contributed to 1.97 million preterm births and 74,000 newborn deaths worldwide in one year (2018), with an estimated 6.69 million years of life lost. Born at 28 weeks. The...
NASA Holidays Boost Launch Odds This Time
I think it will actually launch this time for the simple reason that NASA events and holidays (however small) just like to go together.
Surface Warming Rises Linearly with Cumulative CO₂ Emissions
The scientific consensus is that surface warming is linear in cumulative carbon emissions--there is no evidence of any "tipping point" behavior in global surface temperature (though some climate subsystems e.g. ice sheets may exhibit threshold behavior): https://t.co/9SZ2bigjAM
Spermidine Linked to Heritable Red Blood Cell Longevity Trait
The longevity factor spermidine is part of a highly heritable complex erythrocyte phenotype associated with longevity https://t.co/rHT8XoWHFz