PEP Slows Aging by Blocking Inflammation Pathway
PEP protects against age-related inflammation, puts the brake on the aging process in mice, high levels in humans correlate with low inflammation So what is PEP, you ask? phosphoenolpyruvate, from glucose metabolism, a, master regulator, blocks cGAS-STING https://t.co/glMvaHSjOq https://t.co/MSVMBJbHm4
El Nino Set to Push 2027 to Record Warmth
The El Nino cometh. This would push up our estimate for 2026 global temperatures (though its still unlikely to surpass 2024 as the warmest year), and make 2027 very likely to be the warmest year on record given the historical...
Join Monday’s Live KS2 Science Lesson for British Science Week
I’ll be kick starting British Science Week with a Live Lesson this Monday 1100hrs on CBBC. Also available from Monday at 0900hrs on the @BBC_Teach website. Do you teach Key Stage 2 Science? Need help planning next week’s lessons? Have curious kids?...
Caloric Restriction Extends Lifespan in Animals, Human Applicability Unclear
Dietary (caloric) restriction has so many salutary effects for slowing the aging process in animal models, but whether that can be simulated in some way in people remains unclear. This new comprehensive review @NatureAging is outstanding https://t.co/xw5bmK3NaW https://t.co/t8bBmS8HGB
New Sleep Regularity Index Reveals Hidden Rest Patterns
Interested in the latest sleep science and getting better quality sleep? New Ground Truths with Prof Yo-El Ju, @WashUNeurology https://t.co/2lV3Fw6cwg SRI-sleep regularity index https://t.co/zRWbVNmeap
Self‑amplifying RNA Could Protect Future Heart‑attack Patients
Will we give a shot of protective, self-amplifying RNA in patients with a heart attack in the future? @ScienceMagazine an intriguing innovation https://t.co/FcJme1ElyU https://t.co/lABFRkR3qg
Engineered Astrocytes Use CAR‑A to Remove Amyloid Plaques
New @ScienceMagazine Engineering the brain's astrocytes to clear amyloid plaque! "CAR-A," in mouse model https://t.co/u9zJGnCLUj https://t.co/eIrrFx7iTg https://t.co/x56FDtuVW2
Aging Cells Harbor Protective Mutations That Inspire New Drugs
We're chock full of somatic mutations in our cells and tissue as we age. Some even protect us from disease! And we can learn from them to discover new medications. @CellCellPress https://t.co/mnUsarpYoR https://t.co/4c5XOD7NuC
Iran War Exposes Fossil Fuel’s Hidden Global Costs
On The Climate Brink, my latest post is on what the war in Iran tells us about the hidden costs of fossil fuels https://www.theclimatebrink.com/p/the-war-in-iran-shows-us-another
AI Generalist Excels Across Diverse Medical Imaging Modalities
Can an AI model be a generalist to work and perform well for all types of medical images? Just published, our MedVersa paper @NEJM_AI Led by @pranavrajpurkar Free access https://t.co/5llNf94hAF https://t.co/Bf01zUZ1sk
Yamanaka Stem Cells Earn Conditional Approval for Heart and Parkinson's
20 years of Yamanaka stem cell factor research culminates in 2 conditional approvals for heart disease and Parkinson's disease in Japan https://t.co/8oxKxXYafu by Shinya Yamanaka @CellStemCell https://t.co/U878IxSfSi @ScienceMagazine https://t.co/HCCPaTEP7e
Speleothem Isotopes Reveal Holocene Hydrocl
“Holocene Hydroclimatic Variations Over Western and Central Asia as Inferred From Speleothem Isotope Evidence” | Pleased to be among the authors of this new article in @americangeophysicalunion #JGRatmos led by my former student Liang Ning: https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2025JD045672?prg140729=6ac46daa-138f-4444-9b99-407a402c3282
Spot the Hidden Black Hole in Omega Centauri
You can see a black hole, or at least where one might be. It’s hiding in Omega Centauri. Here's how to spot it!
AI-Driven Data Center Boom Threatens Climate
“AI-spurred surge in data-center development could have climate consequences” by Troy Wolverton for the sfexaminer: https://www.sfexaminer.com/news/technology/ais-power-needs-could-drive-climate-changes/article_b80cc5db-68f6-4697-b2a3-1cd6a07281ba.html
Ancient DNA Reveals 250k-Year-Old Mating Preferences
Neanderthals, modern humans, and the rules of attraction. Here's my story on a tantalizing study on mating preferences as far back as 250,000 years ago. Gift link: https://nyti.ms/4bcNzvy
Space Dust: The Unsung Hero of Astrophysics
Want to learn more about space dust? Check out this post about why dust matters for astrophysicists https://open.substack.com/pub/observinghope/p/the-universe-could-use-a-swiffer?r=dx2wl&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true