Dr. Vinay Prasad “Called For” RCTs. Dr. Peter Marks Delivered Them.
Dr. Vinay Prasad claims he was among the few who called for randomized controlled trials (RCTs) of COVID‑19 vaccines, yet the blog argues that it was his predecessor, Dr. Peter Marks, who actually designed and executed the pivotal trials that enabled rapid vaccine deployment. Prasad now advocates for even stricter RCT requirements for all vaccines, including pregnant women and pneumococcal products, citing “low‑quality evidence” in current approvals. Experts warn that such demands are often impractical, costly, and ethically problematic, potentially delaying life‑saving updates. The piece highlights the tension between rigorous evidence standards and timely public‑health action.
S3NS Announces SecNumCloud Qualification for PREMI3NS
S3NS announced that its PREMI3NS trusted‑cloud platform has achieved the ANSSI SecNumCloud 3.2 qualification, the strictest security standard in France and Europe. The certification guarantees protection against non‑European extraterritorial laws and positions PREMI3NS as the most feature‑rich SecNumCloud‑certified offering. Built on...
Brew City Marketing Launches AI Refresh Program for AI Search, Google AI Overviews & ChatGPT Visibility
Brew City Marketing, a Milwaukee digital agency, launched its AI Refresh Program to upgrade websites for AI‑driven search platforms like Google AI Overviews, ChatGPT, and voice assistants. The 2‑ to 3‑week service improves site speed, structured data, and credibility without...
AdFlow Commerce Announces Premier Partnership with Qode Media SEO Toronto, A Leading Canadian AI SEO & GEO Agency
AdFlow Commerce, an AI‑driven product‑feed and Google Shopping platform, announced a premier partnership with Qode Media SEO Toronto, a leading Canadian AI SEO and GEO agency. The collaboration gives Qode Media priority access to AdFlow’s automated attribute completion, custom labeling,...
b.well Launches the First-Ever SDK for Health AI Assistants
b.well Connected Health unveiled the first SDK designed to power healthcare AI assistants with real‑time, unified medical data. The platform aggregates information from 2.2 million providers, over 300 health plans, and a broad ecosystem of pharmacies, labs, devices, and patient‑generated sources....
Align Continues Strategic Expansion to Accelerate AI and HPC Data Center Deployments
Align is accelerating its U.S. expansion to meet soaring AI and high‑performance computing (HPC) data‑center demand. The company is bolstering vendor partnerships to shorten time‑to‑token for clients and has grown its internal Data Center Solutions team. Align appointed Keith Hopkins,...
Lionsgate Partners Exclusively with FreeWheel to Give Ad Buyers Direct Access to Its Premium FAST Inventory
Lionsgate announced an exclusive partnership with FreeWheel, making its premium FAST inventory accessible through the FreeWheel SSP. The deal covers more than 30 U.S. FAST channels, including flagship MovieSphere and the 50 Cent Action channel, and allows both direct and programmatic...
News Alert: INE Expands Partnerships to Scale Hands-On Cyber Training Across Middle East, Asia
INE Security announced a strategic expansion across the Middle East and Asia, adding new academy partners in Saudi Arabia, the United Arab Emirates, Egypt, and other high‑growth markets. The company’s subscription‑based, hands‑on training platform—featuring unlimited virtual labs and the Skill...
Laserfiche Is a Leader in Info-Tech Research Group’s Enterprise Content Management – Enterprise Data Quadrant
Laserfiche has been named a Leader in Info‑Tech Research Group’s Enterprise Content Management – Enterprise Data Quadrant, earning a composite score of 9.1. The vendor topped the quadrant for product features and customer satisfaction, backed by more than 400 user...
How Can Martech Teams Combine AI SEO And Digital PR To Dominate First-Page Rankings?
MarTech teams must fuse AI‑driven SEO with digital PR to thrive in today’s AI‑centric SERPs. Google now prioritizes entity authority, trust signals, and multi‑surface visibility over simple keyword matches. Integrated platforms enable AI to spot content gaps, while PR secures...
BigBear.ai and C Speed Announce Strategic Partnership to Deliver AI-Enabled Border Security
BigBear.ai and C Speed announced a strategic partnership to fuse BigBear.ai’s ConductorOS AI orchestration platform with C Speed’s software‑defined LightWave Radar. The integration will deliver autonomous, real‑time threat detection and decision support for border security, air‑missile defense, and counter‑UAS missions....
GoDaddy’s New ANS Marketplace Tells You Which AI Agents You Can Trust
GoDaddy unveiled the Agent Name Service (ANS) Marketplace, a platform that lists ANS‑verified AI agents and displays trust signals for each. The marketplace launches with five demo agents—including a Brand Advisor and a Home Page Advisor—designed for small‑business workflows. GoDaddy...
Guard Your Focus: Turn It Into a Competitive Asset
Focus used to be a habit. Now it’s an asset that must be defended. AI constantly invites expansion. Founders who don’t guard focus end up running a portfolio instead of a company.
Proposal to Allow Use of Australian Copyrighted Material to Train AI Abandoned After Backlash
The Australian Productivity Commission has scrapped its plan to grant a “fair dealing” exemption that would let tech firms mine copyrighted Australian material for AI training, after a fierce backlash from the creative sector. Instead, the commission advised the government...
The Arguments for and Against Digital Identification
Fintech commentator Chris Skinner outlines the growing push for digital identity systems, citing government initiatives in the UK, the US mobile driver’s licence, and Apple’s Wallet ID. He contrasts these programs with public resistance rooted in privacy fears, especially around...
Things Worth Reading: 19th December 2025
Chris Skinner’s December 19 2025 roundup curates six fintech stories that illustrate the sector’s evolving landscape. Highlights include Citi’s perspective on funding trends, Aspire’s acquisition of global licences, the emergence of fintech‑driven gambling platforms, HSBC’s £55 million physical‑branch refurbishment, and the Bank of...
GLP Podcast: Evolutionary Mismatch. Is Civilization Wrecking Our Health?
The episode examines the evolutionary mismatch theory, arguing that modern industrialized life bombards humans with chronic low‑level stressors unlike the intermittent challenges faced by our hunter‑gatherer ancestors, leading to physical ailments such as hypertension, immune decline, and reduced fertility, as...
Yann LeCun Looking for $3B+ for "World Model" AI Startup
The episode explains Yann LeCun's announcement of a new AI startup focused on building a "world model" and its pursuit of a $3 billion-plus valuation, potentially exceeding $5 billion. It clarifies what world models are—systems that learn to predict and simulate entire...
As Only Humans Can
The episode explores how Lunar Reconnaissance Orbiter (LRO) data is being used to equip astronauts with rapid visual analysis tools for an upcoming lunar flyby, enabling them to make split‑second geological inferences that only human intuition can provide. It highlights...
Reinventing the Dial-Up Modem (2019)
Simple, a healthcare app, replaced paper registers and landline calls with an offline‑first solution that uses DTMF tones to transmit patient numbers through a toll‑free line. Nurses initiate a call, the app plays the patient’s number as DTMF, and Twilio...
Nvidia's Nemotron‑3 Name Decodes Model Specs
Nvidia just dropped Nemotron‑3 — and yes, the names look complicated… but they actually tell a story. Take Nemotron‑3 Nano‑30B‑A3B‑FP8: • Nemotron‑3 → 3rd gen family, smarter + more efficient • Nano → smallest tier, optimized for deployment • 30B →...
Microsoft AI CEO Admits Gemini 'Can Do Things that Copilot Can’t Do'
Microsoft AI chief Mustafa Suleyman publicly acknowledged that Google’s Gemini 3 can perform tasks that Microsoft’s Copilot cannot, a rare admission in the AI arms race. He highlighted Gemini’s multimodal strengths while emphasizing Copilot’s real‑time visual assistance and integration across Windows,...
Founders Need Q&A Practice—Try This Free Tool
🎙️ After years around startups, one thing stood out: founders spend weeks preparing pitch decks but rarely practice how they answer questions from investor or media. I built a small tool to help founders rehearse answers out loud and get...
Unsloth AI and NVIDIA Are Revolutionizing Local LLM Fine-Tuning: From RTX Desktops to DGX Spark
Unsloth, a GPU‑optimized fine‑tuning library, now runs on everything from GeForce RTX desktops to NVIDIA's DGX Spark, delivering up to 2.5× faster training for LLMs. The tool supports parameter‑efficient methods like LoRA/QLoRA, full model updates, and reinforcement‑learning pipelines, each with clear...
On‑Device Visual Positioning Powers Real‑Time AR Magic
A great visual positioning system makes augmented reality feel like magic... this tech helps your phone (or robot) figure out precisely where it is in 3D space. Here's MultiSet AI nailing it in real-time, at night, and on-device too. This new...
Jason Lee, Head of Chime Enterprise, on the Transformation of Employee Financial Health
In this episode, fintech veteran Jason Lee discusses how employee financial wellness is becoming as essential as health insurance, emphasizing that it drives productivity and business performance. He explains the evolution from DailyPay to Salt Labs and its acquisition by...
Wolfram Automattica
Stephen Wolfram has joined Automattic as a special advisor, bringing his computational expertise to the WordPress ecosystem. Wolfram, known for the Wolfram Language and the knowledge engine behind Wolfram|Alpha, has been engaging with Automattic teams since early 2024. The partnership...
AI Audio/Video Gear Now Affordable and Powerful
20 years ago when I worked at Microsoft a researcher showed me a new kind of microphone he built: an array of four microphones built into a box. It cost about $10,000 for him to build. Now @insta360’s new Wave, https://t.co/MokikgunUR an...
SANS Stormcast Friday, December 19th, 2025: Less Vulnerabie Devices; Critical OneView Vulnerablity; Trufflehog Finds JWTs
The episode highlights a positive trend of fewer publicly exposed industrial control system devices and a roughly 50% drop in SSL 2.0/3.0 exposure, indicating improved server hygiene. It warns about a critical, unauthenticated remote‑code‑execution flaw in Hewlett‑Packard Enterprise OneView (CVSS 10.0) that...
👾 Universal Basic Income Focuses on Stability Not Replacing Work
The article argues that universal basic income (UBI) is a stability floor, not a plan to replace work, especially as AI accelerates job insecurity. It cites forecasts that 22% of jobs could be disrupted by 2030 and that up to...
AI Platform Maps Gene Function at Scale, Redefining Drug Discovery
When I launched insitro , the goal was never to make one drug. If that had been the case, we could have used existing tools. Our goal was to change how drugs are made – and to do that, we...
Stelios Papadopoulos Brings the Long View on Biotech on The BioCentury Show
Stelios Papadopoulos, former Biogen chair and current Exelixis leader, warned that biotech faces heightened pricing pressure and rising competition from China despite a surge of over $3 billion in capital in a single day. He argued that the sector can no...
Amazon in Talks to Invest $10B in OpenAI
The episode examines the reported $10 billion investment by Amazon in OpenAI, framing it as part of a broader trend toward circular partnerships where tech giants both collaborate and compete in AI. It explains what circular deals are, why major cloud...
AI Turns Ideas Into Apps—Join $10K Hackathon
I’m judging the #YouBuildChallenge hackathon (Dec 16–22). The premise is simple: describe what you want to build, and @YouWareAI turns it into a working app. $10K+ in prizes. YouWare is rethinking how software gets created—shifting from writing code to expressing creativity. Built by...
How Alphamab Is Differentiating in Crowded Cancer Targets
Alphamab is launching a next‑generation bispecific antibody‑drug conjugate (ADC) platform that simultaneously engages two tumor antigens while employing a lower drug‑to‑antibody ratio (DAR). The company argues that this design improves the therapeutic index by delivering potent payloads more selectively and...
82% of Companies Are Seeing Positive AI ROI
The AI Daily Brief reveals that 82% of organizations now report positive AI ROI, with 37% seeing transformational impact, and most expecting faster gains soon. The study of 1,200 respondents and 5,000 use cases shows ROI is driven by both...
FinnyAI's AI Boosts Advisor Revenue, Drives $7.7M Asset Gains
Congrats to @FINNYAI on their $17M Series A! The $90T+ wealth management industry still prospects with tools built for other industries, with advisors spending ~60 hours on cold outreach to convert one client. Finny's AI matches advisors with high-intent prospects,...
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Oracle Has One Last Ampere Hurrah - New Cloud Platforms Offer up to 192 Custom Arm Cores, and Aren't OCI...
Oracle Cloud Infrastructure launched A4 Standard instances powered by Ampere Computing’s AmpereOne M silicon, offering up to 192 custom Arm cores per chip in both virtualized and bare‑metal forms. The configurations deliver up to 48 OCPUs (96 cores) with up to...
Grok's Latest Features Boost AI Capabilities
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ChatGPT Asks Replit to Build a Personalized Website
ChatGPT: “Based on what you know about me, make a website with @Replit”
AI-Driven Personalization ‘No Longer Optional’
Udi Ziv, CEO of Personetics, explains that AI-driven personalization has become essential for banks and credit unions seeking growth and retention, as customers now expect the same seamless digital experiences offered by other apps. He highlights the shift from competing...
Founderpath to Deploy $5‑10M Before Christmas, Leading Startup Investor
everyone wants to close before Christmas. busy day at Founderpath today. we'll fund ~$5-10m more before holiday Founderpath is, by far, the most active investor in Software startups by deal count https://t.co/sU5DGqneOU
AI-Native B2B Firms Surge, Seat‑based SaaS Lag
The Great B2B Bifurcation of 2025 Palantir +142%. HubSpot -51%. Despite the fact both businesses end the year pretty strong. Some patterns from the top 25 B2B / SaaS public companies: What's working: 🔼AI-native infrastructure (Palantir, Cloudflare, MongoDB) 🔼Mission-critical + high switching costs (CrowdStrike, Palo...
Third Rock Backs Steve Paul’s Latest Schizophrenia Spinout in $165M Round: Venture Report
Third Rock Ventures led a $165 million financing round for Steve Paul’s newest schizophrenia‑focused biotech, marking a significant venture capital commitment to neuropsychiatric innovation. Paul, a serial biotech founder, will use the capital to move novel mechanisms from discovery into early...
I Tried the Apple Music App for ChatGPT, and It Felt Like Talking to a Music‑obsessed Friend
Apple Music has launched a ChatGPT app that lets users generate playlists, discover songs, and play short music clips via conversational prompts. Subscribers can link their Apple Music accounts to save the AI‑crafted playlists directly to their library. The integration...
AI‑filled Applications Boost Referrals; Network Now
AI slop in the job application process is only going to increase internal referrals processes and network effects. At least 50% of applications I receive are the same AI answers. To the applicant, they seem impressive and well thought out....
Early Signals Stack Up: Two Small Molecules Activate GCase in Parkinson’s
Gain Therapeutics reported Phase Ib data showing that its small‑molecule program reduces glucosylceramide substrate in the central nervous system, confirming target engagement of glucocerebrosidase (GCase). In parallel, Vanqua Bio presented early evidence that its distinct compound activates peripheral GCase while...
YouTube Bans Two Popular Channels that Created Fake AI Movie Trailers
YouTube shut down the Screen Culture and KH Studio channels, which together amassed over 2 million subscribers by posting AI‑generated movie trailers that mimicked real releases. The platforms initially demonetized the creators for missing disclaimer tags, briefly reinstated them, and then...
How Is Europe Rethinking Satellite Connectivity? W/ Craig Bowley
In this episode, SSPI Executive Director Tamara Bond‑Williams talks with Craig Bowley, Regional VP of Sales for Europe at ST Engineering iDirect, about how Europe is reshaping satellite connectivity. Bowley outlines macro trends such as the EU’s IRIS² and GovSatCom...