Token Drain Explained: Skills, Auto‑Memory, MCP Tools
I kept running /compact every 20 minutes wondering why my Claude Code sessions filled up so fast. /context showed me exactly what was eating my tokens. Skills, auto-memory, MCP tools, CLAUDE.md. All mapped out.
Allogene's Interim Data Hints at Off‑Shelf CAR‑T Breakthrough
This week's Biotech Scorecard: Allogene $ALLO: A preview of its April interim analysis. Very interesting (to me, at least) There just might be a path forward for off-the-shelf CAR-T therapy in B-cell lymphoma. Frontline consolidation. Read all about it: https://t.co/tcPFelUH3C
Gene Therapy Turns Aging Into Editable Code
Gene therapy isn't just targeting diseases anymore—it's targeting aging itself. The hallmarks of aging are becoming editable code. Longevity Escape Velocity isn't a fantasy. It's an engineering problem. And we're solving it.
Quick Share Adds Sender Confirmation After Acceptance
Sending files via Quick Share could get a little inconvenient, but it might be for a good reason The sender will be required to confirm the transfer even after the receiver accepts the transfer ✅ Details/Screenshots - https://t.co/sILgw8nAJA https://t.co/6BA93dLtZQ
Rethinking AI Nightmares: Are Our Fears Misguided?
In this week's Torment Nexus newsletter: are we having the wrong nightmares about AI? https://torment-nexus.mathewingram.com/are-we-having-the-wrong-nightmares-about-ai/?ref=the-torment-nexus-newsletter
Historic Turning Point in Protecting Children Online
This week marks a seismic shift in the fight to protect children online — one that history will record as a turning point. 🧵 https://t.co/EbLuef1F62
Claude's New Features Power Real‑World AI Projects
Claude has been dropping new features. Here are 3 projects you can build with them right now: ✨ Competitor Pricing Tracker ✨ Weekly KPI Report Generator ✨ AI Sales Call Prep Assistant If you use Claude, what are you building?
Harvard's Light Chip Enables Sorting Mirror-Image Molecules
Harvard’s twistable light chip could give drug developers a new tool for sorting mirror-image molecules https://t.co/WkjjD38exo https://t.co/5kr4d9f6sa
AI Supercomputers May Soon Orbit Earth for Power
The future of AI infrastructure may move off the planet entirely as space offers continuous solar energy and a natural vacuum for radiating massive GPU heat. If launch costs continue to fall the biggest supercomputers will no longer sit in...
AI Scientist Writes, Experiments, Publishes Papers Autonomously
As a medical school professor, I've spent decades writing papers and reviewing studies. Now AI can do it all -- start to finish. Researchers from Sakana AI, Oxford, and UBC just published in Nature: "The AI Scientist" -- a system that...
AI Learns to See Motion, Not Just Images
Video Understanding: Teaching AI to Make Sense of Motion and Time In this episode of Artificial Intelligence: Papers and Concepts, we explore Video Understanding, a rapidly evolving area of AI focused on helping models interpret not just images, but sequences of...
Smart Defaults Automate GStack, Accelerating Deployment Speed
I'm improving the /land-and-deploy skill in GStack and I am amazed that this is going to work I recommend most GStack users get the hang of /plan-eng-review and other plan skills, but once you get it and get sick of so...
Owning Chips Builds AI Ceiling, Not Renting
Everyone is racing to own the chip. Japan: 3-way merger (Mitsubishi Electric, Rohm, Toshiba) → world's #2 power chip group @Tesla: $25B Terafab fab in Austin Gulf states: buying compute access, building design capability @Zoho: owns its servers, not renting from hyperscalers Same instinct. Different...
Handwriting Helps, yet LLMs Boost Learner‑centric Education
Yes, I think that handwriting does have advantageous effects on learning. But the "iterative dynamics" of large language models facilitate a completely new level of learner centricity that should not be discarded as some evil technological intrusion on #education. https://t.co/IARP1kVmyJ
Eggs as Cheap, Scalable Factories for New Medicines
I have a story today about the quest to turn eggs into low-cost factories for medicines. Gift link: https://nyti.ms/4bzSabB
China Demonstrates Atlas Drone Swarm with AI Combat Upgrade
China unveils full-process demonstration of Atlas drone swarm operations system, expert highlights algorithm-enabled combat upgrades https://t.co/KM8FySikPc
Middle East Crisis Highlights Urgent Need for Energy Resilience
💠The ongoing crisis in the Middle East and its ripple effects on global energy flows serve as a stark reminder of how deeply interconnected our energy systems are — and just how vital reliable, uninterrupted energy supplies are to global...
Code Ran Fine, but Biology Flagged Label Error
I almost sent a figure with wrong cluster labels to my collaborators. The R code ran perfectly. No errors, no warnings. I caught it because cluster 2 showed upregulated genes in RNAseq but reduced chromatin accessibility in ATACseq. Biologically, that's backwards....
Sonos Play: Safe Yet Best Portable Speaker Yet
Here’s my review of the Sonos Play. The company might have played it safe with its first new consumer hardware in over a year, but this is the portable Sonos speaker I’d recommend to most people. https://www.bloomberg.com/news/features/2026-03-26/sonos-play-review-new-portable-speaker-shows-the-company-is-back-on-track
BiotechTV Live Interviews at MassBio State of Possible
Pretty sweet setup for BiotechTv interviews at @MassBio State of Possible Conference today. If you are here, please stop by and say hello.👋 https://t.co/CQtXLi36Qk
AI Shouldn't Replace Teachers Amid Teacher Pay Crisis
I am genuinely not saying this just to dunk on Melania, but this feels like one of the worst uses of AI to champion. I am a moderate AI optimist and believe it will bring all kinds of cool applications, but...
AI's Influence on Human Thought Tops Amazon Rankings
🤔Something very interesting is happening. My book on AI and human cognition is now showing up on Amazon’s top lists in: 🔴Epistemology 🔴Cognitive Psychology 🔴Medical Cognitive Psychology Interestingly, this distribution wasn’t planned. The larger conversation is now shifting, and not about what AI can do, but...
HPE Rebrands Legacy Servers as Modern Cloud‑Native Compute
Hewlett Packard Enterprise (@HPE @HPE_News @HPE_Developer @HPE_Networking @HP) has recently doubled down on its “Compute” branding, attempting to reposition its legacy server business as a modern, cloud-native powerhouse. https://t.co/lRZSHr39wC
Explore Drones, Gambling Impacts, and Vacation Mastery
✍️ Longform links: the drone revolution, the societal costs of gambling, and the art of taking a vacation. https://t.co/r0LEg57JQ5 image: https://t.co/0ikhaAAXsZ https://t.co/DRmlJupZwP
AI‑enabled Incumbents and Workflow Experts Will Lead
This suggests the next wave of winners may not just be AI-native companies, but #AI-enabled incumbents and vertical AI players who deeply understand workflows. #software #innovation https://t.co/YVEyjd2R1Y
ERP Giants Face Threats, May Become Acquisition Targets
ERP providers like SAP, Oracle, and Workday might be acquisition targets as they face business model threats. Companies must decide whether to resist or embrace emerging tech by acquiring it. #ERP #BusinessStrategy #TechAcquisition https://t.co/CLuGMUXxRH
Create 10‑second Videos From Images Directly in Google Ads
Powerful, but will it trick prospective customers? i.e. Will there be realistic expectations? -> Veo Video Generation Now Available in Google Ads "Upload up to three images, and Veo generates unique videos up to 10 seconds long with natural motion. These...
Open‑model AI Startups Emerge as Counterweight to China
A new wave of AI startups is forming around the idea of open models. Backed by Nvidia, companies like Reflection are aiming to build powerful alternatives that are widely accessible, positioning themselves as a counterweight to China’s growing AI ecosystem. The competition...
Lifespan Extension Doesn't Guarantee Morbidity Compression, Study Shows
“These findings challenge the assumption that lifespan extension necessarily compresses morbidity, highlighting the need to consider lifespan, healthspan, and CoM as endpoints when evaluating anti-aging interventions. We do not claim that life-extending interventions categorically fail to achieve CoM; rather, we demonstrate...
Warm Introductions Outrank All Other Prospecting Methods
On my Mount Rushmore of top prospecting techniques, nothing beats #1. Warm introduction from someone in your network. Imagine if your old colleague or close friend introduced you to someone. You'd feel pretty damn compelled to at least respond. And I'd be more...
Seeking Best US Money Transfer App For
What’s the best app for someone in the US to use to send money to me? Tap Tap Send?
Google Gemini Overreacts to Tripterhead Gazette Request
Google Gemini got a bit excited when I asked it to create tonight's Tripperhead Gazette cover...
Build Your AI Skills Library for Compounding Advantage
This week's newsletter is out, and it's about something I've been building obsessively for the last few months. I now have over 50 AI skills covering recurring parts of my work. Not prompts I've found online. Documented processes I've written myself,...
MNOs Embrace Neutral-Host Satellite Constellations
.@MDA_space CEO @MGreenley details status of @Telesat Lightspeed, @Globalstar's 17-sat replacement order and Globalstar's 50+ satellite C-3 constellation and a 'neutral host' constellation idea that MNOs seem to like. @Apple.https://t.co/QiIcACD0Zf https://t.co/EJDK27EjeF
Wind and Solar Power Remain Stable Amid Fossil Price Swings
"Electricity generated from wind and solar is largely insulated from fossil fuel price volatility – once built, the fuel is free." This is what I told @dharnanoor @guardian who published this article. https://t.co/JmVkEskvVq https://t.co/gP1IeOkWVK
GitHub Copilot Will Train on Your Code—Opt Out
Anyone tired of this yet? -> GitHub’s Copilot will use you as AI training data, but you can opt out "GitHub says it will use Copilot interaction data, including inputs, outputs, and code snippets, to train its AI models...
Salvaged Tesla Battery Powers Ukrainian Lights Amid War
His totaled Tesla showed up on the app — charging in rural Ukraine, a year after the accident. Someone salvaged the battery. Now it's probably keeping the lights on during Russian blackouts. War repurposes everything. https://t.co/3W8ezKpCFR
ARC-AGI-4 Slated for Early 2027, Yearly Benchmarks
For those wondering about ARC-AGI-4 timing: it will be released in early 2027. We are aiming for a yearly release schedule for new benchmarks. We are also aiming for each new benchmark to be fully unsaturated upon release, and to...
Tech Accelerates Clinical Trial Recruitment of Ideal Participants
I spoke to a startup building software to help clinical trials recruit more of the right kinds of people more quickly - a serious challenge at present.
Anti‑TGFβ1 Antibody Shows Durable Efficacy, Low Toxicity
Scholar Rock's anti-TGFb1 antibody clinical study with early data in oncology indications... minimal AEs and signs of durable efficacy in checkpoint-refractory patients. $SRRK https://t.co/8xsN4wtbMV
Google Mandates Greyed‑out Add‑to‑cart for Out‑of‑stock Items
Google Merchant Center now requires out of stock product pages to have greyed out add to cart/buy buttons https://t.co/LdscAbqaMh via @FeedArmy https://t.co/myyYJiEUQT
Tesla Superchargers Now Pop Up at Wawa, Sheetz
Based on two recent road trips, all the new Tesla Superchargers are at Wawa and Sheetz? ;) https://t.co/u8D2W0kqGU
Merchant Center Titles Dominate; Price Data Must Align
Ecommerce SEO: when it comes to ranking within free listing results on Google, there is a sphere of influence for data sources. This relates to features such as product grids, product knowledge panels, within the Shopping tab, AI Mode...
AI Now Contains Cyberattacks in Seconds, Humans as Exception Handlers
27 seconds. That's the fastest observed cyberattack breakout time. Average: 29 minutes. CrowdStrike + IBM just integrated their AIs for machine-speed containment. Human analysts are no longer the first responder. They're the exception handler. https://t.co/47q7R5dt3q
Coruna iPhone Exploit Kit Tied to Operation Triangulation
News about an iPhone exploit kit called Coruna has generated a lot of buzz. Boris Larin (@oct0xor) of the GReAT team digs into the kit and explores the attack chain. And yes, there are clear links to Operation Triangulation. Details:...
Companies Blame AI for Layoffs Despite Limited Capability
Interesting and apt @wsj highlighting “AI washing” - attributing corporate layoffs to AI vs usual reasons. In most cases fear of AI >> capabilities of AI (at least right now) to actually do most jobs. @zakkohane https://t.co/6Ur4GCG7RX @JamesBessen https://t.co/7vXBnQOUt9
TurboQuant Cuts Model Memory 6×, Boosts Speed 8×
Google Research introduced TurboQuant, an algorithm that compresses AI model memory over 6x without any retraining — while delivering up to 8x speed gains on Nvidia H100 chips and losing almost zero accuracy https://t.co/SaBOGCwqfm #ArtificialIntelligence #Innovation #Technology #Tech #TechNews
Taiwan Spends $600M Extra as LNG Prices Double
Taiwan spent an extra $600 million to secure LNG through June to replace lost Qatari supply 🇹🇼 💰 Taiwan’s Economic Minister said spot LNG prices are “about twice as high as long-term contract prices with Qatar” The island depends more on gas...
Prescribing CORT Lifyorli Differs From Cushing’s Experience
Here's prescribing info for $CORT Lifyorli -> https://t.co/i46Whl5lX6 Why so different from the experience in Cushing's? https://t.co/EqvbCApqHn
AI Transforming Trading and Fund Management – New Article
A new article dropping from Zach tomorrow about AI and its role in trading and funds management. If you're not already signed up, you can do so here >>>
