Ahrefs Rolls Out Interactive Widgets, Structure Reports, Enhanced Brand Radar
Some recent Ahrefs updates: -Interactive widgets in the MCP -Site structure reports added to Web Analytics and Bot Analytics to get breakdowns by section -More info in Brand Radar to see the difference when pages were used to generate vs if they were cited.
Prelude Tx Unveils Early-Stage KAT6A Degrader
Looking through my #aacr26 collection of posters from yesterday. Prelude Tx have a KAT6A degrader (PRT13722) in early development to compete with inhibitors: https://t.co/23zBtCX8Hs
Eyes Offer Highest Bandwidth Brain‑Digital Interface, Awaiting Neuralink
I am trying everything I can to directly connect my biological mind to the digital mind of my Openclaw based Virtual Intelligence and Operations Center. Eyes are the highest bandwidth interface from my VIOC to my brain. Typing and voice...
Three Questions Leaders Ask to Solve Growth Challenges
3 Questions Leaders Can Ask To Identify Solutions For Growth Problems - https://t.co/5SRry0MFlm - https://t.co/Vucmh7iPcq
UN: Renewables Boom Demands Massive Critical Mineral Mining
On Earth Day, UN Secretary-General calls for unleashing "the renewables revolution" - a push that inevitably will require far more mining/processing of critical minerals
Personalized CRISPR Poised to Become Standard Care
How individualized CRISPR genome editing can go from rare, expensive use to broader accessibility and a standard of care by @UrnovFyodor and Sadik Kassim @Nature https://t.co/ddc5ASPPAK https://t.co/GOFneIyuai
MIT Creates AI‑controlled Artificial Muscles Mimicking Human Movement
MIT researchers just replicated human muscles with AI-controlled fibers. Inside each fiber is a sealed tube of electrically charged liquid and a tiny electric pump. When the pump activates, one side contracts while the other relaxes, just as your biceps and triceps...
Detail Matters: Apple CEO’s Screw‑Groove Lesson
Incoming Apple CEO John Ternus gave commencement speech at Penn Engineering School in 2024. He does version of Steve Jobs “paint both sides of the fence even if other people don’t know” attention-to-detail story…about screws for the Cinema Dislay...
OpenAI Bets on Compute Edge over Anthropic
Seems like one of the ways OpenAI hopes to win against competitors is by having all the compute. Anthropic is clearly pulling ahead in many technical/ethical ways, but they may not have the compute to back up their powerful models.
Sex Chromosomes Drive Cancer, Autoimmunity, and Brain Disease
Our X and Y chromosomes play a bigger part in health than acknowledged, including cancer, autoimmunity, and neurologic conditions. A new @nature feature https://t.co/IjVNbXzBPB
Lamb Weston Shares Plunge 20% Amid SAP Lawsuit
Lamb Weston's stock dropped 20% after problems were disclosed. A pension fund sued the company, CEO, and CFO, alleging they didn't fully disclose the magnitude of issues from a botched SAP implementation. #BusinessNews #Corporate https://t.co/vuGqpFaYyu
Merck Expands AI Push; Roche Reports MS Drug Data
Merck adds to pharma’s AI push; Roche details MS drug results https://t.co/VmpWyLhP9A $MRK $RHHBY $TGTX $RCUS $GILD #biotech
U.S. Retreats From Seas; Who Will Police Space?
Really good point. If the US is pulling back from policing the high seas, who will police the assets in outer space?
Chinese Battery Makers Lean on Gas Amid Lithium Crunch
Volt Insight briefing: Chinese battery companies' reliance on natural gas, CATL's mining push, and the lithium squeeze. Read more and sign up to my newsletter here: https://t.co/IUiScW74cK https://t.co/qZWMUx3kbM
Give Free AI Credits, Bet on Value Over Pricing
AI costs are usage-based. Customers want flat pricing. Procurement needs a fixed number. Karel Papik's solution: give away massive free allocations and bet on the value. Risky. Working. https://t.co/XgtC5QcNvW
New Receptor Enables Bat Alphacoronavirus Entry Into Humans
Discovery of a new receptor by which alphacoronavirus from bats can get into human cells and the potential for transmission https://t.co/LE5sTVyfkS @Nature https://t.co/aszqnDMQqE @NatureNV https://t.co/ejnvrvr6BO
BMO Launches Governance-First Institute for AI and Quantum
BMO Centralizes AI and Quantum Efforts Into Governance-First Institute to Scale Responsible Innovation Launched enterprise-wide institute for applied AI + quantum technologies. Coordinates expertise: data science, governance, ethics, commercialisation. Goals: accelerate responsible AI adoption, improve client experience, boost operational efficiency, develop...
Google Signs Multi‑billion Deal for Nvidia GB300 AI Chips
Exclusive: Google deepens Thinking Machines Lab ties in a deal valued in 'single-digit billions,' per a source familiar. Includes access to Nvidia’s new GB300 chips + infra services to support model training and deployment. https://t.co/2fywSlR1Kp via @techcrunch
AI‑Designed Enzymes Accelerate Corporate Partnerships at SynBioBeta
@SynBioBeta isn't just where startups find investors. It's where Fortune 500 companies find their next technology partner. @IFF is one of the world's largest flavor, fragrance, and biosciences companies, with over $11 billion in revenue and a century-long track record of...
Most Firms Overestimate AI Governance; Ownership Gaps Persist
The AI governance mirage: Why 72% of enterprises don’t have the control and security they think they do “When asked about the single biggest obstacle to governing AI across platforms, “no single owner or accountable team” ranked second at 29%...
VR Therapy Shows Promise for IBS Treatment
Most people think of VR as gaming. In clinic, we’re using it to help patients manage IBS—alongside meds and diet. We’re looking forward to presenting results from our first IBS randomized controlled trial at #DDW26 in Chicago Non-drug therapies are having a moment. @DDWMeeting...
FDA Approval Could Ignite Peptide Boom and Doping Grey Zone
Peptide space is going to blowup if FDA approves it. Interesting grey area for sports doping.
Open‑source Home Assistant Unifies Fragmented Smart Home Devices
I got that little Home Assistant box https://t.co/q6afmz6k14 I can highly recommend Home Assistant in general, I was recommended it by @johnonolan and @daniellockyer I remember When I bought my house I hated home automation and didn't want any, cause I had...
Rising Fuel Prices Boost Solar, EV, Heat Pump Demand
🎙️ Just on @AlJazeera on war & clean energy. Double-edged sword — but I'm optimistic long-term. High fuel prices make clean energy more economic than just weeks ago. Demand for solar, EVs and heat pumps is surging. https://t.co/3WP8kG7awM
Frontier AI Models Risk Degrading, Exposing Enterprises to Breaches
Article I'm quoted in on Forbes on the recent Claude model degrading. Note, I am not anti-Anthropic in anyway. I loved Opus 4.6 when it first came out. I almost bought a I <3 Claude t-shirt (kinda joking there). My...
Gumroad Offers SaaS Sales with 5% Fees
Gumroad is getting into helping people sell SaaS. We're a Merchant of Record (handle all sales taxes) and can reduce our fees from 10% to 5% if you're selling downloadable software. Email me if you're interested: sahil@gumroad.com
Cloud Run Users Double; New AI Features at Next ’26
In 2025, the number of Cloud Run external monthly active developers and applications doubled. If you are running AI Agents, vibe coded apps, AI inference, or scalable apps, there's something new for you at Next ‘26:
Redefining ‘First‑in‑Class’ Amid Faster Competing Therapies
How do we define “first in class” when there are others further ahead? This example is from Atheron Therapeutics w/ a CCNE1 degrader #aacr26 https://t.co/s22biREUrt
Wet AI Using Brain Cells Could Outperform GPUs
Here's our story on The Biological Computing Co. It's an inside look at how it's using human and rat brain cells to help discover new AI processing algorithms that mimic how neurons actually behave and learn. Will the "wet" AI...
AI Rewires Home Lights, Ditches Harsh LEDs
Today I hacked my Home Assistant with AI to nuke the bright white LED spots that came with my house when I bought it They're absolutely horrific to look at, they burn into your eyes, all new Portuguese houses come with...
Anker THUS Chip Enables Large AI on Wearables
Anker THUS chip breaks computing rules to put big AI models on wearable devices https://www.techradar.com/ai-platforms-assistants/anker-thus-chip-breaks-computing-rules-to-put-big-ai-models-on-wearable-devices
Substack Posts Often Trigger Subscriber Loss, Sometimes Due to Offense
When you publish a Substack post it's typical to lose some subs. People sign up everyday, maybe someone told em it's good whatever. They get an issue decide meh unsubscribe. Some days you lose extra subs & I have to...
Australia Emerges as Ideal Market for Satellite Systems
“Australia is our fourth-largest market. We’ve seen a lot of demand in Australia. In some ways, if you were designing the perfect market for a satellite system, it’s exactly Australia,” via The Australian Financial Review. https://t.co/nt5BfUmaLx
Originality Trumps Quality: Mediocre Content Can Still Rank
High-quality content is no guarantee of SEO success. Sometimes, mediocre content is good enough. New research unpicks the impact of originality on rankings. https://t.co/ekjjFaGVnk via @sejournal
Enterprise AI Must Be Accurate, Contextual, and ROI‑Driven
Some people think AI can write enterprise-ready software. But ChatGPT can’t run your payroll or report your earnings. It doesn’t know your people, your data, or your rules. If we want AI to actually to solve actual enterprise business processes,...
Embracing a Claude‑centric Feed without Complaint
Now my entire feed is all about how to use Claude. I’m not upset about it.
Claude Code Unlocks Previously Impossible Feats for 67% GTM Operators
New data: 67% of GTM operators say Claude Code enabled something previously impossible. Not "saved time." Impossible.
AI Undermines Pareto, Unlocking Profitable Niche Markets
The Prosperous Society, Part 3: The Collapse of the Pareto Principle In Episode 3, I make the case that artificial intelligence stands to erode the Pareto Principle as it applies to production, as AI-empowered distribution efficiencies will enable firms to reach niche,...
Tiny Data Center Gas Projects Outpace Morocco’s Emissions
"New gas projects linked to just 11 data center campuses around the US have the potential to create more greenhouse gases than the country of Morocco emitted in 2024." -Wired There's a better way. At Firma Power we're chatting that way...
AI's Future Mirrors Cold War Socialist Planning Debate
Everyone loves the nuclear analogy for AI right now. It presses all the sexy buttons: power, destruction, governance, etc. Fair enough, but here's another Cold War analogy I've been noodling on: the socialist calculation debate. In the 1920s Mises argued socialism...
Rethinking Phones: An Open‑Claw Alternative to Smartphones
ok what about a phone that isnt a trad smartphone but is kinda an openclaw on the go
Higher Spend Doesn't Guarantee Greater Share of Voice
Just because you're spending more money on a set of target accounts doesn't mean they see you more than your competitors. There's a good chance that your extra investment is being matched by the same level of extra investment from...
CDC Vaccine Efficacy Report on Halved Winter Hospitalizations Shelved
The #CDC report that showed the #Covid vaccine halved the risk of a recipient needing emergency care or hospitalization this winter has been shelved by HHS, @bylenasun reports. https://t.co/tCNx8LSIKn
AI Generates Realistic Luxury Email Mockup in One Prompt
ChatGPT Images 2.0 made this with a single prompt and no edits. Here's the full prompt I used: Create a full-length, tall vertical ecommerce email mockup for MVMT, a modern watch and accessories brand for millennials. Design a highly realistic premium DTC email...
Dell XPS 16 Marks Impressive Return to Form
I reviewed Dell's latest XPS 16, an impressive return to form for the brand. It's sleek, surprisingly lightweight, and I'm a fan of that tandem OLED screen. Dell also addressed aspects of the keyboard and trackpad on prior laptops that...
Master AI SEO with TTO: Track, Talk, Own
How to make it in the AI SEO era: TTO. 1 TRACK your LLM traffic 2 TALK to your customers 3 OWN the query fan-out ↓ Let's dive in! https://t.co/8Fjprzc5p1
AI's Quiet Revolution: Vision Tech Optimizes Retail Operations
Most people think AI in retail is about self-checkout, but the biggest impact is happening behind the scenes. Computer vision is now used for shelf monitoring, loss prevention, and safety by tracking inventory, detecting risks, and identifying issues in real...
EMP‑01 Shows Strong Patient‑Reported Gains in Social Anxiety
What incredible news to wake up to! Some weeks ago, @ataibeckley reported positive topline results for EMP-01 (oral R-MDMA, a patent-protected version of #MDMA) for Social Anxiety Disorder(SAD). The data reported was the reduction in symptoms as reported by the treating...
ECB Fuels US‑payment Paranoia to Accelerate Digital Euro
ECB's Piero Cipollone is currently being grilled by Nicolas Veron on the digital euro in a refreshingly sharp way. Veron just pointed out that the ECB's paranoia about the US payment companies pulling out of Europe is somewhat far-fetched, to...
Congress Moves to Make AI Core of U.S. Foreign Policy
Foreign Affairs committee is going to vote for a bill to dedicate U.S. foreign policy to promoting AI. In case you were worried that someone might object on behalf of normal people, Dem ranking Greg Meeks is strongly for it.