Stopping GLP‑1 Therapy Quickly Erodes Cardiovascular Protection
A new finding after stopping GLP-1 drugs in a large cohort with Type 2 diabetes: rapid erosion of CV benefit/protection New @bmj_latest by @zalaly @Biostayan https://t.co/JG6yB8wTJJ See thread: https://t.co/6JvfIIjVBw https://t.co/wUgWhvs9Yy
Meta Shuts Down VR Metaverse, Quest 3 Fans Bewildered
Meta is pulling the plug on its VR metaverse and Meta Quest 3 fans don't know how to respond https://www.techradar.com/computing/virtual-reality-augmented-reality/meta-is-pulling-the-plug-on-its-vr-metaverse-and-meta-quest-3-fans-dont-know-how-to-respond
MiniMax-M2.7 Sets New SOTA, Handles Incidents
MiniMax-M2.7 is here. → matching Sonnet 4.6 as an agent → recovering live incidents in just 3 minutes → hitting SOTA in SWE-Pro (56.22%) 🔥 It even edits your Office files 👀
Missing Social Media Messages Can Kill Your Brand
Near misses are dangerous to your health. Near misses in #SocialMedia can be fatal to your business. A miss means your message isn't being heard by potential customers. Your brand could crash. https://t.co/6CgUC488Df
Agentic AI Demands Diverse Compute Engines: CPUs, GPUs
Agentic AI will require all kinds of compute engines, including CPUs, GPUs, DPUs, and now LPUs. $NVDA $GOOG $AMD $INTC https://t.co/WVnnc36X2U
Measure Real Conversions Without Pixels, Compliantly
Healthcare marketers lost pixel tracking. Now what? Russell Reid explains how teams can still measure real conversions — compliantly.👇 Learn more: https://t.co/EqD4ALkqrm @AllianceInno @nex_analytics #hcmktg https://t.co/3jIOMDiCO4
Dell UltraSharp 52 Makes All Other Screens Feel Lacking
The only downside of the @DellTech UltraSharp 52 is that when I move away from it I hate every screen I use
Avoid Risky AI Search Tactics; They Damage SEO
One of the worst things you can do for AI search visibility? Destroying your SEO performance with shiny new AI search tactics that are ultimately dangerous for SEO - and by extension - AI search. In my latest Substack article, I wrote...
AI Agents and Status Signals Redefine Global Scaling
Global expansion, social status, and AI agents are reshaping how companies scale. On #DisrupTV, @ValaAfshar & @RWang0 talk with Russell Haworth and @tobystuart about designing global products, hyper-localization, and how status signals influence decisions in an AI-mediated world. https://t.co/zZJqIjFU7Y
AI Needs SaaS Guardrails for Enterprise Governance
Everyone talks about AI's "magic," but no one talks about Governance. 🏛️ Enterprise apps require layers of compliance that AI isn't ready to handle solo. SaaS isn't dying; it’s providing the guardrails AI desperately needs. Read the AVOA analysis: https://t.co/tqCcpQvgpK #CIO #Cloud...
Top Homebuilders Trust ResiClub for Data-Driven Decisions
Teams inside major homebuilders, lenders, and operators are using ResiClub research and analysis to inform real decisions—including firms like Meritage Homes, a giant homebuilder ranked No. 554 on the Fortune 1000. That’s exactly what we’re aiming for: clear, data-driven housing market...
Fortinet Bets on AI, Silicon, and Edge Data Centers
.@Fortinet’s sees advantage in AI, chip, data center investments https://t.co/l4n1P1c5O0 Fortinet is betting that long-term investments in its own AI data centers and silicon, being early to quantum-safe offerings and AI agents moving to the edge will drive its results...
Gemini API Merges Function Calls with Built-In Tools
YES. Instead of separate calls or agents, now you can combine function calling with built-in tools (like Google Search) in a single Gemini API call. This simplifies a few of my own agents. https://t.co/R97to7Af8U
IOS 26.3 Beta Adds New Live Weather Wallpapers
Apple keeps enhancing and expanding the live weather wallpaper and lock screen options in iOS 26. Here are some of the latest options in iOS 26.3 [release candidate beta] and how to try them... https://t.co/iwvpGclM5d #iphone #ios26 #weather https://t.co/oeQXLP7NP4
Arena Leads AI Rankings While Maintaining Neutrality
LMArena (now just Arena) has become the AI industry's top leaderboard. CEO @ml_angelopoulos walks us through how @arena remains neutral in its rankings, even though it partners with/accepts money from the top AI labs. This week on @EquityPod https://t.co/6aXZeXjFMp
AI Bots Free Doctors for Patients, Not Just Tech
Dr. Selene Castrejon doesn’t run a tech company. She runs a medical practice. Every hour she spends on admin is an hour not spent with patients or growing her business. Inside the AI Business Lab® Mastermind, she built trained AI bots...
AI Permission Fatigue Creates Hidden Security Risks for CIOs
Devs are getting numb to AI permission prompts the same way everyone ignores Terms of Service. Those "approve" clicks can open doors to security, data privacy, and compliance risks CIOs will own. #CIO #AI https://t.co/p18hdtdbZn
AI Agents Are Full Tech Stacks, Not
AI agents = full tech stacks, not just LLMs. 🧊🤖 Above water: UI + “smart” assistant. Below water: 🧠 models 🕸️ orchestration 🗂️ memory/RAG 🛠️ tools & APIs 📊 AgentOps/observability 🔐 auth & security 🗄️ data + ETL ☁️ infra Great agents are systems + governance + data, not prompts. What layer...
Compact Six-Axis PiPER Arms Deliver Industrial Versatility
PiPER #Robotic Arms: Compact Powerhouses with Six-Axis Precision and Industrial Versatility by @IntEngineering #Robots #EmergingTech #Technology #Innovation https://t.co/cVTBeXATHt
Infrastructure Unveils IgniteAI Agent for Canvas LMS
Infrastructure launches IgniteAI Agent for Canvas, builds on @Amazon Bedrock https://t.co/0iOP4GmXpI Infrastructure, the company behind the Canvas learning management system (LMS) launched the IgniteAI Agent, which orchestrates and executes workflows for…
EHRs Will Become Records; AI-Driven Action Layers Rise
Sharp take here from healthcare VC Sam Toole on the future of EHRs in an AI world. Do they become systems of record, and entrepreneurs can build systems of action that sit on top? Link to read the full piece...
Patreon CEO: AI Fair Use Claim Bogus, Pay Creators
Patreon CEO calls AI companies’ fair use argument ‘bogus,’ says creators should be paid https://t.co/MwnGr36nbk
AI Valuations Likely Overinflated, Reset Imminent
VC Bill Gurley sees a reset coming in AI. His point is simple. When a real wave hits, a lot of money is made quickly, and that’s usually when excess builds up. The question isn’t whether AI is real. It’s whether valuations...
MDA to Add Three Optical Sensors by 2028
@MDA_space to build/maintain 3 ground-based optical space surveillance sensors by 2028 to complement current 150-kg Sapphire sat, launched in 2013. Valued at CAD 32M ($23.4M), it's part of CAD 375M @NationalDefence Surveillance of Space 2 program, to include Sapphire successor....
Asia’s EV Surge Ends Fossil Fuel Dependence
Emerging Asia is sprinting toward electric independence to crush fossil fuel fragility. Fossil fuel wars will only accelerate this trend ➡️Viet Nam: 38% EV sales share, ahead of EU ➡️Singapore: Leading the charge at 50%+ share ➡️Indonesia: 15% share, more than US ➡️Thailand: 21%...
In‑body Genome Editing Promises Cheaper, Practical CAR‑T Therapies
What if we could engineer T cells in the body, making CAR T vs cancer, autoimmune diseases, and other applications far more practical, much less expensive? A step forward today via genome editing T cells https://t.co/FjgQA8NUlu https://t.co/XXk43WL1ac https://t.co/rpC7eCAlJH
AI Generates My Weekly Plan with Deep‑Work Focus
One prompt I run every Monday that plans my whole week: ↓ "Pull my goals for this quarter. Look at what I shipped last week and what rolled over. Check my calendar for the week ahead. Build me a realistic weekly...
Talent Engineering Is the AI Speed Bottleneck
A good heuristic for whether your company is moving fast enough for AI: Append "engineering" to every function. Then rate it. GTM → GTM Engineering ✅ | Product → Product Engineering ✅ | Talent → Talent Engineering ❌ Talent is where it breaks....
Bootstrapped Founders Can Attract VC Love Beyond Capital
When my friend raised $6M and I told him I was sad to lose another bootstrapper to the VC dark side, he said something that totally dumfounded me. Him: “We're building a generational company and not planning on raising any...
Early Rubin GPU Access Confirms Nebius as True Partner
$NBIS priority allocation from Vera Rubin clearly signals that Nebius is being treated as a real partner That matters because in AI infrastructure, getting the newest GPUs early directly translates into attracting top customers and higher-margin workloads. This validates $NBIS strategy...
Universal Semantic Layer Needed for Multi-Tool Data Access
The semantic layer isn't new. SAP BusinessObjects had one in 1991. What's new is the need for a universal semantic layer that works across BI tools, notebooks, and applications. When you only had one BI tool, that tool's semantic layer was enough....
AI Slides That Prioritize Thinking Over Aesthetics
I've tested literally every AI presentation tool on the market. They all make the same mistake: they focus on making slides look good. This is the first one I've seen that focuses on making the THINKING good. Built by ex-McKinsey + ex-Apple AI....
Artemis II Rollback to Launch Pad Tomorrow at 8 PM
Artemis II SLS/Orion rollback to the launch pad is now set for tomorrow, Thursday, March 19, at 8:00 *pm.* It'll stream on NASA's YouTube channel.
Trustworthy, Transparent AI Agents Redefine Future Work
The future of work isn't just AI agents. It's AI agents you can trust. Fully observable. Fully editable. Finally.
Only Practical, Defensible AI Solutions Will Endure
The Unglamorous Moat: The Truth About What Will Survive The #AI Bubble by Katy Wigdahl @Forbes Learn more: https://t.co/TGm6ejRgoC #ArtificialIntelligence #MachineLearning #ML #DL https://t.co/WbOmruLTMm
Coding Agents Combine LLMs, Prompts, and Tools in a Loop
A coding agent is basically an LLM + system prompt + tools in a loop. @simonw spells this out in another great guide about how coding agents work. https://t.co/ywlRRAU3VY
Apple Adopts Account‑age Verification for UK Online Safety Act
glad to see Apple using account age as verification for the UK’s Online Safety Act in iOS 26.4. This is how you do it 👍 https://t.co/XghbR7Oi4w
Switch to Fiscal AI—A No‑Brainer Solution
If this is happening to you as well... Switching to @fiscal_ai is a no brainer.
Instant QR Code Health Record Sharing by Flexpa
This is @Flexpa. @Flexpa enables patients to instantly share verified health records with any provider via a QR code. A big thanks to @USDS for helping enable the vision and mission of Flexpa: Flexible Patient Access. https://t.co/fD0qjuBtWy
AI Outbound Fails without Clean, Accurate Data
Last week I got an outreach email congratulating me on our Series D. Ahrefs has never raised a single dollar. We're bootstrapped. So someone's AI agent pulled the wrong data, mashed it together, and confidently sent me a "personalized" message that was...
Invest in These DTC Essentials, Not Fancy Extras
A few things that are actually worth the money (for DTC operators): • A founder who will record videos • Knowing contribution margin before opening Ads Manager • A creative producer you can text at 9 am and have content ASAP • Raw over...
AI Flattening Organizations Threatens Traditional Middle Management
What happens to middle management when AI flattens your organization? https://t.co/mDJARBQNMZ #AI #management #business #technology #leadership
Prophit Engine Delivers Accurate Forecasts, Consistent Growth, Lower Costs
More isn't always better. Better is better. Forecast more accurately, grow contribution more consistently all while saving money with the Prophit Engine from CTC. Big love to the boys: @Seanfrank @iamshackelford @Jaredorkin @stevenborrelli @steviej @SJohnson_89 for the acting brilliance. This one is a...
AI Race: Choose Your Role, Not Victory
A tough take on the AI race. For most countries, it may already be out of reach. Backing local players that will never be first could end up wasting time and capital. So maybe the real game is not winning it, but...
Turn Customers Into Creators, Cut Ads, Grow 50%
Chubbies grew 50% year-over-year by turning 1.5M customers into content creators. Free UGC from their 'Chubster Nation' replaced paid ads. Meanwhile you're spending on ads with no community behind your brand. That's the gap.
UK Power Mix Flips: Renewables Now Dominate, Coal Gone
When I started working on UK energy in 2007, fossil fuels provided ~78% of electricity. Coal alone: 34%. Wind & solar: less than 2%. Today: wind & solar 33%, fossil fuels 28%, coal 0%. The chart below tells the story better...
AI Agents Poised to Capture Up to 25% E‑Commerce
J.P. Morgan & Mirakl Nexus Unveil AI Agent Checkout A first-of-its-kind solution designed to enable secure AI agent checkouts for enterprise merchants. J.P. Morgan’s tokenization and fraud protection to allow agents to move from "browsing" to "buying" within a regulated framework....
Desktop AI Vell
Holy shit... someone just built an AI that lives on your desktop, has its own email, its own accounts, and actually does things while you sleep. It's called Vellum and it's actually secure. I can't imagine going back to the way I...
Brain Organoids Play Video Game, Demonstrating Cellular Computing
It's the future it's possible that we'll use cells plus silicon for compute. In this experiment, scientists used a mouse brain organoid (brain-in-a-dish) to play a video game, showing living cells can solve digital tasks. Reaching 46% proficiency in a...
Mouse-Inspired Robot Mimics Brain for Place Recognition
How a Mouse-Inspired Robot Learns to Recognize Places Like a Brain by @lukas_m_ziegler #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/mYyjnlLD6k
