VibeJam Games Leap Forward in Visual Clarity
One thing I'm starting to notice is the visual style of the #vibejam games this year is way better Last year the model's still had a real hard time understanding visually what they were building, they were essentially blind A one year later they're able to make this:
KLF5 Drives Pancreatic Cancer Spread via Gene Rewiring
A gene called KLF5 may be a key force behind the spread of pancreatic cancer—but not in the way scientists expected. Rather than mutating DNA, it rewires how genes are turned on and off, helping tumors grow and invade new...

Fatty Acids Target and Eliminate Aging “Zombie” Cells
NEW STUDY finds certain fatty acids selectively kill senescent "zombie" cells. The molecules exploit a fundamental biophysical weakness in senescent cells, a totally new approach. Could we simply consume these moleculs to treat aging? ...🧵 https://t.co/EceCAfdlvz
Short‑Form Content Drives 15× Weekly View Surge
I simply decided to make short form content again and we are 15x the views week over week. Literally 10s of millions more Return of the King
Superhuman Cybersecurity Tool, Not True AGI Yet
Not at all sure this is AGI, and in fact doubt that it meets my criteria of parity with human cognitive capabilities in general. But it's a superhuman cyber security tool. ASI is narrow. AlphaGoZero is a narrow ASI. Mythos...
AI Security Mirrors Existing Controls, Not a New Paradigm
Is AI security actually different? The categories look familiar: Shadow AI, Shadow IT Agent identity, IAM AI vendors, TPRM So what is fundamentally different about security for AI related threats?

Artemis II Just Got an Amazing Upgrade
I mean COME ON. Just when you think Artemis II can't get any better, this drops. 🥹
Shingles Vaccine Beats Geroscience in Reducing Dementia
a different take: the shingles vaccine lowers dementia and all cause mortality and it’s targeted to a specific virus, not the process of aging so far the data say the score is shingles vaccine 1, geroscience hypothesis 0 and I could say the...
Prioritizing Proven Safety and True Level 3 Autonomy
Again, it would be nice if the focus was on provable safety increases and real Level 3 capabilities but we'll see.
AI Front‑Runners Act Responsibly, Defying Sci‑Fi Corporate Villains
In science fiction, the corporations are often evil doers. In the AI world right now, we're pretty fortunate that the three companies at the frontier are fairly responsible actors, making proactive choices in the interest of the public good.

New Cytotoxic Targets Unveiled at AACR26
Time to head off the beaten track at #AACR26 with our latest preview exploring novel targets and cytotoxics. The long climb up the hill may be worth it for some of them: https://t.co/l9tkdWvpuF https://t.co/M5B3RTW1wf
27 Essential LLM Questions for Enterprise RFPs
I don't think I've personally seen an enterprise RFP with a full list of LLM-related questions. Here are 27 questions that you might be asking already before choosing an LLM ... https://t.co/tM4gEUVuyR https://t.co/O75Oq6lXKr
Memory Dominance Determines AI Compute Winners for Years
If the winners and losers in AI compute come down to who gets the most memory in the most ridiculous memory-constrained market we have ever seen.... For the next 3-4 years.... Predicting those winners is pretty easy.

PE Funding Forces Anthropic’s Enterprise Rollout, Not Market Demand
The headline says Anthropic is going enterprise. That is not the real story. They put in $200 million. Blackstone and two other PE giants put in up to a billion more. To sell Anthropic’s own product for them. Private equity has something...
Anthropic AI Uncovers Vulnerabilities Across All Major OSs
Anthropic’s new AI model has found security problems “in every major operating system and web browser.” Anthropic is only previewing the model with partners like Microsoft, Google, Amazon, Apple, and Nvidia due to security concerns https://t.co/HV5u8X7UnY
SEO‑dead Hype Turns Into 410 Page Deletions
Also the same companies who pushed the narrative (and $$$) that SEO is dead/dying last year are now using 410 response codes on the pages they helped scale/rank&tank for their clients last year. I wish I was kidding.

Configure Android Backups Now to Prevent Data Loss
Is your Android device set up properly to back up all of your precious data? How about your photos and videos? Here's a primer on how to get it all configured correctly before it becomes a crisis: https://t.co/0SKNFevQhS #android #backups...
AMD Likens CUDA Battle to Mountain Climb, Doubts RT Rollout
.@AMD being humble, says taking on @NVIDIA’s CUDA is like climbing a mountain… 👇🏽 Then again, why will AMD RT this? 🤔 @dvellante @furrier @Srasgon @dfloyer @Scobleizer @om @karaswisher
Premium Lite Expands to 15 New Countries Worldwide
Exciting news: this week, we’re expanding our Premium Lite tier to 15 new countries around the world, including Vietnam, Belgium, Peru and more 🌎 Read more: https://t.co/z3Kz1el86I
Realizing 10X Impact Triggers True AI Adoption
The “AI moment” is when someone realizes: “I can do 10X more impactful work.” That’s when AI adoption actually happens. #Kaihan #Outthinker #AI #FutureOfWork #Leadership #BusinessTok #Innovation #AIAdoption https://t.co/JAM3uj3gtl

US Awards $48.9M LEO Tactical Comms Contract to IonQ
US @SemperCitiusSDA awards prototype contract to @IonQ_Inc 's @capellaspace to demonstrate tactical waveform/beamforming/secure tactical comms in LEO under HALO, Europa Track 1 solicitation, for up to $48.9M for 2 space vehicles, w/ demos to be completed by November 2027. https://t.co/7VCm9ATINm
SFO Shelters Waymo, Prioritizes Uber/Lyft Over Safety
SFO approved Waymo — then buried it at the Rental Car Center. Meanwhile, Uber and Lyft run 800K trips/month from the main garage. Zero safety rationale. Pure incumbent protection. https://t.co/53a332crtg

Artemis II Flyby Images Reveal Humanity’s Cosmic Awe
My favorite images from the #ArtemisII lunar flyby yesterday. Images that remind us of the immense majesty of the cosmos. Images that remind us of how small we are. Images that remind us of how special we are, how precious...

2026 Kicks Off with Bank‑Fintech Mergers and Massive IPO
"We saw a busy start to 2026 – Between banks acquiring fintechs, fintechs acquiring banks, merchant acquirer PayPay's $12.7 billion IPO, and prediction markets platforms acquiring over 273,908 new users each month." - @itssophievo for @twifintech https://t.co/aIs9zyJRvu
U.S. Must Lead AI Security Race Against China
As you read about Anthropic's Mythos capabilities to find critical security weaknesses, consider what if a Chinese AI company had gotten here first. There is a real race underway, and its in our interest I believe for U.S. companies to...
AI Transforms Messy Notes Into Polished Drafts Instantly
📋 You know what belongs in that rubric. ⏳ The formatting is what slows you down. 💡 AI can turn your messy notes into a polished starting point. https://t.co/GDB21nrz89
Anthropic Tests Claude Mythos Rigorously; Others May Follow
Anthropic putting Claude Mythos through its paces before releasing it. But will other leading-edge companies do the same?

Future AI
Frontier models will one shot just about anything few years Intelligence is compression Jevons law is more of a suggestion https://t.co/hUNI1fD6Fl
IPhone's Biggest Milestone: First Device Used in Space
I don't care about the iPhone Fold — the biggest moment in iPhone history just happened in space https://www.techradar.com/phones/iphone/i-dont-care-about-the-iphone-fold-the-biggest-moment-in-iphone-history-just-happened-in-space
Trade‑focused “Lambda School” Could Thrive for Decades
My hot take of the day is that a Lambda School for electricians, CNC machinists, and other advanced manufacturing roles would do very well for the next 20+ years. Maybe longer.
Artemis II Images Transformed Into Stunning Poster Series
Couldn't resist turning the incredible Artemis II photos from @NASA into a poster series https://t.co/Epab5X0JNn
Crowdsourced Prep Becomes Norm for Frontier AI Rollouts
fascinating new cadence for releasing frontier models is emerging that crowdsources preparedness before distribution, probably a new norm? any new tech that exceeds human potential must be rolled-out in a way the addresses the vulnerabilities and abuses that evaded our awareness
Content Is Easy; Distribution Is the New Competitive Moat
AI gave every marketer access to a content production engine. BUT.... It did not give them a distribution strategy. Output is not the advantage anymore. Distribution is. Most people are sprinting to create. The winners are sprinting to build a distribution moat...

SEO Firms Race to Game AI Search Citations
The AI search boom created a new arms race as SEO firms and brands tried to manipulate search to get cited by ChatGPT, Gemini, and Google’s AI tools https://t.co/hxKdN24GNX #ArtificialIntelligence #Innovation #Technology #Tech #TechNews https://t.co/2QgbSDAR9y
Anthropic Leads AI Safety, Beats OpenAI Expectations
Two years ago, if you asked me which lab will be the first to say: “this AI model is too powerful to release, so we’ll wait with it” - my guess would have obviously been OpenAI. Who else? That Anthropic...
Russian Lunar Launch Delays Repeatedly Rehashed, Yet Unchanged
Russia media quote a RAN official today about the latest delay of Russian lunar missions, however all these "new" dates had already been known since at least January and reported here... and will certainly be delayed again: https://t.co/oxFsJRelFu
Artemis 2 Update Conference Rescheduled to 4:45 Pm ET
Today's daily Artemis 2 update press conference is now at 4:45 pm ET rather than 4:30 pm ET. Listen on: https://t.co/5WwQdsBQIl
Free Guide: Using AirOps MCP with Claude AI
I’m giving away free sauce on how to use @AirOpsHQ MCP with @claudeai so plz so give me a heart or a comment or something if this was useful ok thanks bye https://t.co/ce7k2Sl49Q
GWP20: Faster Climate Action for Methane Benefits Health
GWP20 for methane greenhouse-gas accounting is good policy in NY State & beyond, as Prof. Bob Howarth and I explain in a response (https://t.co/86Dm2bq6zw) to a recent claim that GWP100 should be used instead Both California and New York...
Hold AGI Until World’s Bugs Are Fixed
If you had AGI would you release it to the world? I wouldn’t. I would fix the bugs in the world first. This technology in the wrong hands would harm us all. In good hands it will help all.
AI Empowers Solo Creators, Sparking Long‑Tail Product Boom
We're now seeing legitimately useful products launched almost daily by individuals or small teams using AI, not venture funded startups. Some recent examples: @MattHartman's Ghost Pepper @bensig and @MillaJovovich's MemPalace @garrytan's Gstack The explosion of the long tail feels imminent...

Four Core Systems Power a Responsive Supply Chain
The Four Pillars of Your Supply Chain Information System To build a truly responsive supply chain, you must understand the specific software sources that feed your data. In our latest lesson, we dive deep into the four essential systems that power...

Russian “Starlink” Satellites Begin Maneuvering, Developer Remains Silent
A couple of "Russian Starlinks" from the 16-bird group showed first signs of maneuvers, based on the US data, but there has been no word from the developer about the status of the mission since its launch on March 23. UPDATES:...

IPhone‑Mac Mirroring Boosts Seamless Phone‑computer Switching
Late to this but iPhone mirroring on mac is a massive unlock if you are switching between phone/computer constantly https://t.co/3bkoi6m3Yu

Orion Spacecraft Snaps Backlit Moon During Solar Eclipse
The Moon, seen here backlit by the Sun during a solar eclipse on April 6, 2026, is photographed by one of the cameras on the Orion spacecraft’s solar array wings. https://t.co/3GkEIJ7NBT
Funding Hurdles Stall Needed Multi‑site BPC‑157 Trial
I can’t see any reason why a proper multi site RCT of BPC157 done by a few independent groups wouldn’t help clarify any real vs placebo effects. The challenge: no one wants to pony up the $ (more like $$$$...
Anthropic Teams with Cyber Industry for Security Safety
Project Glasswing - big news that Anthropic partners with cyber/software industry on cyber security safety. https://t.co/rGKMOgcvTc
AI Threatens Furry Community by Replacing Erotic Fanfiction Writers
Between this and AI reportedly taking the jobs of erotic furry fanfic writers, I'm starting to think that AI is a weapon designed to destroy furry culture
Auto Prompt Caching Cuts API Costs Silently
https://t.co/AEF7gEgoGs Auto prompt caching is a feature built into most popular models and it is quietly saving on your API prompting costs.

Google Search to Evolve Into Multi‑Agent Task Manager
Jarvis -> Sundar Pichai sees Google Search evolving into an ‘agent manager’ “If I fast-forward, a lot of what are just information-seeking queries will be agentic in Search. You’ll be completing tasks. You’ll have many threads running.” “Search would be an agent...