Sharing AI 2041 Jan 11th Amazon-US-only one day promo: $1.99 for Kindle and $0.99 for Audiobook, with 陈楸帆Stanley Qiufan Chan Penguin Random House https://lnkd.in/g94Kck_v

Plugins + SaaS print money. Live on @acquiredotcom: All-in-one website design plugin for Squarespace freelancers and agencies. Faster builds, no custom code, sticky subscriptions. > $340K TTM revenue > $223K TTM profit > 39% YoY growth Full listing: https://t.co/Y8gnOYsd82 https://t.co/kiUkoUUPCu

Salesforce, Datadog & Epic are building walls. After two decades of flourishing through open APIs & data portability, the software industry's largest incumbents are locking down. https://t.co/7n6Tio3aJK
"If I had 2 more great humans, I'd hire them tomorrow. If they were truly great. But a Pretty Good AI agent is better than ... hiring a human that isn't great. We don't need placeholder hires anymore. AI Agents...

AI tools aren’t the edge. System design is. Chatbots = interface Automation = leverage Knowledge = memory Data + workflows = ROI Tools are replaceable. Capabilities aren’t. https://t.co/wpNCwkjyBo
Would you wear an AI camera hanging around your neck? @Looki_ai shows off an AI listening and assisting device. My 12th #CES2026 report. What if the data is all yours? Soon many of us will be wearing cameras on glasses. I would, but...

If you’re a student or a professional using AI daily, you’ve seen this happen. A prompt works great today. Tomorrow it gives a weird answer. Next week it breaks after a model update 😅 A prompt that works once for one model isn’t reliable. A...
Advanced Robotics: UC Berkeley This is course is from Peter Abbeel and covers a review on reinforcement learning and continues to applications in robotics. If you work on robotics… this one is worth bookmarking‼️ MDPs: Exact Methods Discretization of Continuous...
I spoke to a founder who sent 15,000 cold emails. The result? Near zero responses. He fired his marketer. Hired an expensive agency. Still zero results. The problem wasn't the execution. It was the STRATEGY. Here is the 6-step GTM framework that works...
I was on a call with a Founder the other day. His growth was stuck. So we got to diagnose the issue. The culprit? They had sent 15,000 emails. And got back zero real responses. They tried blogging. Posting online....
Why most AI products fail: Lessons from 50+ AI deployments at OpenAI, Google & Amazon @Aish_Reganti and @KiritiBadam have built 50+ enterprise AI products across companies like @OpenAI, @Google, @Amazon, and @Databricks. Based on these experiences, they’ve developed a small set...
Good morning on this Sunday before #JPM26! I wrote a JPM opener newsletter with some advice for all of you: Chill out. The super-sized gathering of the biopharma universe is important, but it’s not going to make or break the...
Biotech capital markets are clearly open for business: $2.6B in public FOPO so far in January, the most ever pre-JPM conference. Private VC financings of over >$2B in the same period. Investors clearly have cash to put to work......
8 types of LLMs powering modern AI agents — clearly mapped in one visual. From GPTs and MoE to Reasoning Models (LRM), Vision-Language Models (VLM), Action Models (LAM), and Hierarchical Reasoning (HRM), this shows how agents are no longer “just...
#Meningococcal disease has been rare. But when it occurs, it is devastating. High death rate. Survivors often lose limbs, as this person did. There's no way to accurately assess who is at risk. And yet meningococcal vaxes are no longer...
You need a better reason for someone to act rather than a “better” CTA. • Scarcity is fake. • Urgency is overused. Be clear, specific, and honest. People aren’t dumb, they’re just overloaded with garbage. Stand out by not insulting...
Dear Leaders and experts in fields relating to “Artificial Intelligence” (all types and tools including specifics of how human data is used as the origin or basis for any system design and use) and “Ethics” (meaning formal philosophy, law, policy...
Walmart is hedging its AI bets. Gemini from Google, ChatGPT from OpenAI. When consumers start shopping through chatbots, retailers can’t afford to be absent. Link: https://t.co/fjexyHFvSa
Never hire anyone in sales that doesn't care about money You'll see
Shopify is building the foundation for agentic commerce. Universal Commerce Protocol, which we co-developed with Google, is now live. UCP will make it faster for agents and retailers to integrate. It’s open by default, so platforms and agents can use UCP to...
I was recently chatting with Dan Pfister (author of Million Dollar Winback) about the real reasons SaaS companies lose customers. He shared a story of how one SaaS company dropped churn from 18% to 3% by changing who they sold...
Hiring slowdowns aren’t isolated right now. Many companies are holding headcount flat, protecting capital, and waiting for more clarity before expanding teams. Attrition is also unusually low, which tells you something about uncertainty in the market. 👉 Efficiency, not expansion, is the current...
Sometimes it’s not what you say, but how you say it. Or, as a brain scientist would would say, how you frame it. The words you choose can make the difference between someone liking your product or not. Someone agreeing...
Incredible work by @mikulaja @kontigo_app was at best a naive puppet for sanctions violations At worst a knowing participant. The whole stablecoin industry is on notice Get your AML and Sanctions controls buttoned up or there will be blowback It's when not...

Free tutorial: bulk RNAseq analysis from fastq to GSEA analysis (watch the full playlist) https://t.co/v0UHRSqJ63 https://t.co/LtdxPNYG5Y

Most startups don't fail because they build bad products. They fail because they try to serve everyone. One of the biggest lessons for us this past year at Univid was narrowing down the niche harder - not expanding it. https://t.co/RlCp4pBsvI

Looking at bioinformaticians’ profiles these days, you'd think everyone has decades of experience in cutting-edge single-cell and AI-driven bioinformatics. But something’s missing… 👇 https://t.co/yvmvcwXWyr

Fintech Biz Weekly just dropped: Y Combinator & Coinbase invested in a Venezuelan sanctions evasion app linked to the Maduro regime, including, rumors say, the son of Nícolas Maduro: @kontigo_app The story is a LONG one. You know where...
The Next Generation of Multi-Functional I&I Therapeutics | Ep. 903 How to Pick Winners From a Crowded Cytokine War Bispecifics are everywhere, China biotech is running every combo possible including the ones you have not thought of yet. Trispecifics are next, and...
Build your startup like you’re going to run it forever but prepare it so you could sell it tomorrow. > Organized books > Standardized operations > Product that works without you That’s how you create real leverage with buyers.

1/ 💡While much of the immunology field is fixated on immune reset in B cells and autoimmunity, a quieter version of the same idea is emerging in cardio-immunology. 🫀 Except we are not talking about lymphocytes. This is all about tissue-resident macrophages. And...
If everyone starts using GenAI to draft, read, and summarize all their emails then nobody will know what they (or anyone else) originally wrote or said. I’ve been getting emails with people sending short abstracts to lead committees etc and...

True Sovereign AI ≠ “we host it locally”. It’s control over: • Data • Model architecture • Compute • Inference • Data centers • Value creation Miss one layer → no real sovereignty. #SovereignAI #AIInfrastructure #Geopolitics #AIStrategy https://t.co/gnsSF6dd1I
“Bullshit” — The New Way Health Giants Hide Billions" https://t.co/6PcmoY1pmh This PBM GPO investigative story makes my blood boil... these intermediaries are why the list-to-net spread for many drugs is over 50% in the US... siphoning off dollars at the expense of...

When The Bubble Bursts: Tips For Businesses Considering #AI by Larry Bradley @Forbes Learn more: https://t.co/rbwQ66SL6Q #ArtificialIntelligence #MachineLearning #ML https://t.co/NDMSLRRt2a
A #Robot snake for rescue missions by @lukas_m_ziegler #MachineLearning #Robotics #EmergingTech #Innovation #Technology #TechForGood https://t.co/EqkASnEqPH
Robots that plan by imagining the future. Large Video Planner (LVP-14B) from MIT is a robot foundation model built on video generation instead of vision-language-action. Instead of predicting actions directly, it generates a short video of how a human hand...
Phantom MK-1: Foundation’s New Humanoid #Robot Aimed at Factories and High-Risk Environments by @IntEngineering #Robotics #MachineLearning #ArtificialIntelligence #ML https://t.co/Je3O6f2zLI
Sports Store Uses #AI #Robots to Model Clothes in Real Motion by @MrLaalpotato #EmergingTech #Technology #Innovation https://t.co/my69zqyT5j
Evolving #Robot Hand: A Versatile Adaptive Gripper for Manufacturing, Education, and Research via @ZappyZappy7 #AI #MachineLearning #ArtificialIntelligence #Innovation #Technology #ML https://t.co/e4sMEZNIiU
I’ve had several discussions this week with executives who are still struggling to define and act on clear AI Strategies for their businesses. This is not from a lack of trying. And, it’s certainly not from a lack of experience,...
I don't think you should quit your job tomorrow. Honestly, that's bad advice most of the time. What I do think is that you should stop giving all of your best energy to a company that would cut you loose...
What does it take for a 10x exit? These are the 4 pillars... Scale: $10M–$15M+ ARR Growth: ~40% year-over-year Retention: 120% NRR / 95%+ Gross Retention Profitability: Break-even or profitable

China’s Plans for Humanlike #AI Could Set the Tone for Global AI Rules by Claire Cameron @sciam Learn more: https://t.co/hxK8MbONkn #ArtificialIntelligence #MachineLearning #ML https://t.co/Lv9UdYSCGN

If @Tesla_Optimus 3.0 has these hands I will let it cut my hair. Best at CES because hand innovation leads us into the future. 1,000 sensors in a finger. Plays ping pong. Deals cards. Does origami, fun things by folding paper. When I...

Product skills of the future: - Intuition about what's worth building - Clarity in describing the solution - Taste in knowing when it's great - Agency to do the above without being asked

🚨On Thursday, almost 600 days since Synapse/Evolve end users had their funds frozen, Evolve announced that it, I guess, “found” some more money — https://t.co/ZpCcjXfezR
Market Fatigue: The Need for Quality Deals I recently sat down with Jim Williams to catch up on the state of Software M&A. Have an "A" asset? There are plenty of buyers who want your business. Listen to the full...
If you want people to buy, don’t just show what your product does. Show what they become because of it. People want transformation more than features. Sell the identity shift, the status, and the story. That’s what actually converts.

There’s no “best” AI. ChatGPT = creativity & coding Gemini = Google Workspace + live info Claude = long, technical reasoning Grok = real-time trends Perplexity = cited research Power comes from using the right tool per task. #AI #GenAI #LLMs #Productivity https://t.co/KfCo6FAJte