Ask AI for Complete Thoughts, Not Label‑style Snippets
A surprisingly simple prompt that I use all the time when asking AI to write something for me: ↓ "Write complete thoughts, not compressed label-style phrases dressed up as sentences." BAD: Each week is one workflow, one habit to practice. GOOD: Each week we'll focus on one workflow from the workshop and establish it as a daily practice.

AI Rivalry Reveals Career Paths and Industry Philosophies
The Wall Street Journal just published a decade of OpenAI vs. Anthropic drama. Personal feuds. Pentagon deals. Two $300B companies racing to IPO on opposite philosophies. Most people will read it as gossip. Here's what job seekers should actually take from it 🧵...

Natural SIRT1 Activators May Shield Early Alzheimer’s Microglia
Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation-Energy Axis? 🗣️"We will describe how SIRT1 can represent a key molecular link and an appealing target to harness microglial neuroprotective potential as...
Lead Magnet Finally Tried, Email List Grew
For >10 yrs, I have been reading advice in various places to put a lead magnet on my personal website, in order to capture more email addresses. I finally took this advice approximately one month ago and, perhaps unsurprisingly, it worked. Follow...
Do You Pay for Your Claude Code Plan?
Which Claude Code plan do you have? PS: Do you pay for it or your company?
MRK's Sotatercept Shows Inverse Dose Response in 6
$TENX $TECX 🤔 $MRK sotatercept high dose *missed* stat sig on 6MWT in P2 (and it wasn’t particularly close). The low dose hit stat sig (barely) and was the dose taken to P3. What to make of a...

Agentic AI Shifts Focus From Answers to Execution
Agentic AI = more than intelligence 🤖 • Proactive decisions • Goal-driven actions • Context awareness • Real-time learning • Human collaboration • Resource optimization • Scalability • Ethics It’s not about answers anymore. It’s about execution. #AgenticAI #AI #Automation

AI Won’t Eliminate Jobs in Five Years, That’s the Myth
The biggest lie about AI is that it will wipe out human jobs in the next 5 years...Here’s what everyone’s missing👇
RKLB: The Only Viable
The Ashlee Vance book is phenomal on the rocket companies $RKLB is the only serious player outside of the billionaire companies Hoping it gets back to a cheaper multiple again
US Stalls Progress: Regulations, Not Tech, Hold Back Innovation
Why is it so damn hard to do big things in America? Australia has 40% rooftop solar. We have 6%. We can build beautiful homes in a factory for $300k delivered. Local regs block it. The technology isn't the problem. We are. https://t.co/IBSjsr4eDl
Social Media Evolving Into AI‑driven Lead Monitoring Platform
Why social media is turning AI. I've resisted doing this, but am working on a social media platform myself to at least watch my DMs in various places for leads. And am getting close to turning on a site to watch...
Crossing 99% Sim‑Real Accuracy Triggers Digital‑First Production
The Economic Engine of Physical AI. {🧵 Full breakdown below.} After this, you should understand… • why 99% sim-to-real accuracy is the tipping point • how simulation replaces hardware • how ROI shifts in production design • why Digital First...
Get Rich by Going All‑in on Free AI Tools
If you want to get rich, go ALL in on AI. You don’t need money. You don’t need experience. You just have to learn to use the free tools available to you. Stop pretending not to know.
Use AI for Drafts, but Own the Final Output
There’s a question I’ve been mulling for a while now, and I think it’s time to write it down: when is it okay to use generative AI in a given business context, and when does it cross a line? I’ll...
Two Analysts Deliver Unbiased Autonomy Podcast
Highly recommend this podcast on autonomy, FSD, etc They actually do fair and rigorous journalism — unlike @nytimes and @wired Just two analysts going direct

GLP‑1 Drugs Now Help Psoriatic Arthritis Beyond Weight Loss
The list of conditions for which GLP-1 drugs provide benefit independent of weight loss keeps growing. Add psoriatic arthritis #AAD26 @AADskin https://t.co/kJej6osXTS
India Targets 346 GWh Battery Storage by 2033
Indian industry body projects 346 GWh of BESS capacity by 2033 #energysky -- via pv magazine global: https://t.co/Obs4o92i3V
Algorithms Turn Content Into Ultraprocessed, Irresistible Streams
Much of the digital content that ensnares our attention is "ultraprocessed", i.e. "the result of vast databases of user-generated content that are sifted, broken down and recombined by algorithms into personalized streams designed to be irresistible". https://t.co/QDr9Jzu8Y9
Universal Physical AI Powers Robots Across Tasks Instantly
Nearly every major industry is bottlenecked by one thing: scarce human capital. Skild Brain is changing that. Their AI just assembled GPU racks live at NvidiaGTC, one of the most precise tasks in hardware manufacturing. Here's what makes it wild: Most robot AI is...
Should AI Use Short-Term Copyrighted Works Freely?
So if we shortened copyright to 28 years, should AI companies then still be allowed to vacuum up my work without permission and payment? If no then Whats the principle you are advocating? I don’t understand why you’re arguing with...
Questioning AI's Free Access to Musicians' Catalogs
What long term good is gained by AI companies having free access to my songs and catalog? Does the world not have enough recordings and songs? Does it cure cancer? You haven’t told me why it’s in anyone’s interest? Yet...

SGLT2 Inhibitors Help HFrEF Mice via Off‑Target Effects
SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice “The beneficial effects of SGLT2i treatment in gKO mice conclusively demonstrate that in a physiologically relevant preclinical model of HFrEF, SGLT2i can exert therapeutic benefits via off-target pharmacology.3...

Aer Lingus Launches Starlink Wi‑Fi on Dublin‑NY Flight
Aer Lingus passengers traveling from Dublin to New York JFK on flight EI105 today are the first to experience the carrier’s new Starlink inflight Wi-Fi https://t.co/aReJBNtST7 #paxex #pressrelease https://t.co/1ks7572jJ8
Open‑Source Laser Engraver Available Fully Assembled for $64
Open source laser engraver sells for just $64 fully assembled — it is small and low power but may be enough for your needs https://t.co/IBv2QUqJOj
One Typo Can Break a Million-Line Build—VC & Tests Needed
"A single character typo broke the build for a 1,000,000 line code base" <-- this can easily happen and isn't a big deal. Version control + automated testing fix this. Those two things are generally weak in CAD...

Raschka Releases Free, Research-Grade LLM Architecture Gallery
Sebastian Raschka is one of the most respected voices in ML/AI education. And he just shipped something quietly brilliant. 👉 An LLM Architecture Gallery — a single, browsable reference that maps the internal design of modern open-weight models. This isn’t a blog...

Compliance as Code: GENIUS Act Redefines Financial Infrastructure
🔺 Is the "old era" of compliance finally dead? 🪦 In this episode of Fintech Conversations & Insights, Beth Haddock (Stablecoin Standard) explains why the GENIUS Act is forcing a total rethink of financial infrastructure. We dive into: ❌ Why "Honeypot" data collection...

GStack Adds Support for Factory Droid Integration
GStack now supports Factory Droid @FactoryAI Thanks for getting me to do it @matanSF https://t.co/SxAE6Q6mjK
Meta Advances AI Object Understanding with SAM 3D
SAM 3 and SAM 3D: Meta Platforms Pushes #AI Object Understanding Further by @AIatMeta #GenerativeAI #EmergingTech #Innovation #Tech #Technology https://t.co/wnnZzU3Nw9
AI Agents Replace Sales, Scheduling, and Family Coordination
Claire Vo 's first day with OpenClaw it deleted her family calendar. Now she runs 9 agents across 3 Mac Minis, and said "I haven't felt like this since I was a teenager learning to code." Her sales agent Sam...

Google's TimesFM Enables Zero‑Shot Forecasting for Any Data
🚀 Google just open-sourced a Time Series Foundation Model — and this changes forecasting as we know it. Meet TimesFM. Unlike traditional time-series models that require: • dataset-specific training • feature engineering • constant retraining 👉 TimesFM works out of the box — with any time-series...

QuEPP: Quantum‑Enhanced Pauli Propagation Boosts Error Mitigation
Another highlight from last week, Swarnadeep Majumdar presenting work on QuEPP (Quantum Enhanced Pauli Propagation), our new take on the classical-quantum combination for error mitigation: https://t.co/v7o45niZV8 https://t.co/gb52BzVOUS
Vintage Tech Revived: Community Keeps 30-Year-Old Hardware Alive
This is a REALLY fun one from @PCMag. I love stories about people getting 30-year-old hardware working again and the homebrew communities around them (I do Atari 8-bit and Minidisc myself) https://t.co/xBKhC2ZBeu
AI Innovation Often Serves Vendor Interests Over Customers
Is AI innovation truly customer-focused, or is it vendor-driven pressure? Vendors aggressively push AI, not always for business value, but to lock customers into ecosystems and gain pricing leverage. #AI #SaaS #VendorPressure https://t.co/3zlZDocRpn
Premium Clients Trump Massive LinkedIn Follower Counts
About two years ago, a marketer with a massive LinkedIn following sent me a competitor’s profile. The marketer said, “I see how you’re showing up on LinkedIn, Jay. Check out this competitor of yours.” We both sold advisory services to...
AI Drafts Full Degree Proposal Faster than Coffee
Can AI create a comprehensive degree program proposal in the time it takes to grab a coffee? https://t.co/JlmwZl2a2t

SaaS Multiples Dip as Growth Steadies at 14%
SaaS valuations just hit multi-year lows — while growth is stabilizing. Over the past 12 months, the setup has quietly flipped 👇 • Median EV/Sales fell to 3.44x (at ATL) • NTM revenue growth rebounded to +14% YoY Valuations compressed. Growth held. Growth expectations stopped...
Five Proven Strategies to Elevate Remote Engagement
5 Ways to Boost #Remote Employee Engagement @perceptyx https://t.co/99TAqSAx4S #HCM #HRM #HumanResources #HRTech #CHRO #FutureofHR

More Ring Shots, Featuring Ghostly Jane for Reference
You guys liked the last batch of Ring photos so much, here’s a couple more from another angle. Standard Sam wasn’t in frame, so we’ve added in Ghostly Jane for reference. https://t.co/a5vqFxvfgc
Jetson Thor Humanoid Robot Gains Full Autonomous Mobility
Jetson Thor–Powered Humanoid #Robot Achieves Fully #Autonomous Wheeled Mobility via @ZappyZappy7 #Robotics #ArtificialIntelligence #MI #ML #Tech #Innovation https://t.co/DQDf7xWFor
AI Data Centers Turn to Mass Timber for Greener Footprint
AI Data Centers. Wood you look at that. Data centers are typically constructed primarily of steel and concrete—but as the AI data center wave accelerates, Meta and Microsoft are pivoting to build them with mass timber to help reach their...
Europe’s Real Breakthrough: Efficiency, Electrification, Cheap Energy, Secure Supply Chains
The real breakthrough we need isn’t fusion. Europe needs to do 4 things at once: - Use less material per unit of prosperity (Negabarrels) - Electrify everything possible - Overbuild cheap energy - Treat supply chains like national security
Programmatic AI Content Won’t Give You Competitive Edge
Could not have said this any better myself. I am working with an early stage founder right now that is HUNGRY to scale scale scale with programmatic content -- yet this creates zero competitive advantage if you are just automating...
From Prediction to Execution: AI’s Three Evolution Stages
This pyramid is the cleanest way I’ve seen to explain why AI feels so different depending on how it’s used. Here’s the executive takeaway 👇 1️⃣ Traditional AI = Prediction & Detection Forecasting Classification Anomaly detection Value: insight Limitation: rigid...

Writing Genomes Opens Post‑Darwinian Era of ABI
Artificial Biological Intelligence (ABI) In a post-Darwinian era of being able to write genomes, the implications—both for good and harm—are profound. In conversation with @AdrianWoolfson on his new book On the Future of Species https://t.co/2OahzzxAAa
Edge Computing in Space Cuts Data Transfer Overhead
Generically, it’s an IT arch that distributes computing so processing is closer to where the data is generated, which makes data xport more efficient and versatile. In this case, it means processing data in space, on the Ring, vs dumping...
AI-Powered Micro‑drones Navigate Using Bat‑like Echolocation
Tiny drones are learning to navigate like bats. By combining ultralight sonar with AI, they can move through dark or low-visibility environments using echolocation-style sensing instead of relying only on cameras. It’s another example of how AI is not just improving software,...

Unearthing Hidden Claude Skills Through Random Mentions
The discovery of Claude skills still is an unsolved problem. I learn of the most insane high-impact skills from throwaway mentions in some reply somewhere. My mobile browser is full of links like these. What’s the most impressive Claude skill...

AI Merges Health Data and Calendar Into Infographic
Here is the simple prompt. It hit my Apple Health database and my work Google Calendar. Then I asked it to create an infographic. A few turns but not many. (Note the misspelling it just ignored). https://t.co/zj1jir75no

Eliminate Spreadsheet Chaos, Boost Sales with PIM
Product data all over the place? Clean it up and sell more. Our Perfion PIM blog shows how to kill spreadsheet chaos. 🚀 Blog: https://t.co/6FLdt6Eqx0 Schedule a meeting with me: https://info.quaintbusiness. https://t.co/Hi7sCEGpow