Google's AMIE Shows Promise, Still Needs Clinician Partner
A great discussion by the brilliant @AdamRodmanMD on the new study of @Google 's AMIE (medical AI) tool, including the study's limitations. Bottom line is the tool's performance is impressive and getting better, but it's still best thought of as clinician-partner, not "AI MD."
Drug Patents: Near-Term Generic Threat, Mid-Term Safeguards, Tirzepat
AI: Short-Term Cliffs (0-3 years remaining): Drugs like sacubitril/valsartan, dapagliflozin, pembrolizumab, ocrelizumab, daratumumab, and apixaban face imminent generic/biosimilar pressure Mid-Term Protection (4-7 years): Risankizumab and dupilumab have solid runway, supported by ongoing label expansions. Long-Term (8+ years): Tirzepatide's robust patents position it...
AI Work Capacity Doubling Every Year—Prepare Now
In 2020, AI couldn't do your job for 30 seconds. In 2026, it can do it for 7 hours straight. You have one year before that number doubles. Here's how to prepare:
Classical Heuristics Advance Guides Future Quantum Chemistry
In this thoughtful essay, Garnet Chan reflects on recent progress using classical heuristics in computational quantum chemistry—and what it means for quantum computing. The lessons he draws can help to steer both classical and quantum approaches in scientifically productive directions. https://t.co/XSXMNQTy3b
GPT 5.4 Beats Opus 4.6 in Smarts and Precision
gpt 5.4 in codex is real smart - feels smarter and less sloppy than opus 4.6 tbh
Intelligence Embeds Everywhere: Key MWC 2026 Tech Trends
MWC 2026 — The IQ Era Is Here And These Are the Trends Every Business Leader Needs to Watch From intelligent devices to AI-native networks, Mobile World Congress 2026 revealed how intelligence is becoming embedded across technology and infrastructure. Read...
China TOPCon Module Prices Rise After March Cargo Clearance
China TOPCon module prices edge higher as March cargoes clear #energysky -- via pv magazine global: https://t.co/RHIugNwXio
Stop Over‑crafting Prompts; Just Collaborate with AI
If you're still trying to craft the perfect prompt for your favorite generative AI chatbot, you're doing it all wrong. Here's how to properly work with generative AI to get the best results and also have the most fun: https://t.co/xG88ex3xEb...
Anthropic Reveals AI Deception, Offers Misalignment Inoculation
In this Anthropic paper, the model moves from “reward hacking” into more generalized misaligned behavior, even inventing deceptions to hide the behavior when being observed. Lessons: 1. They learned valuable lessons on how to prevent and even “inoculate” against the...
AI Agents Can Breach Chatbots, Heralding AI‑vs‑AI Warfare
An AI agent reportedly hacked a chatbot and gained full read-write access in just two hours. This is the emerging reality of the agent era: AI systems interacting with other AI systems, probing, exploiting and learning faster than traditional security models...
Unsupervised Tesla Robotaxi Test Highlights Autonomous Future
Just dropped a new #AutonomyMarkets episode. Watch or listen on your favorite podcast player. We Rode in a Tesla Unsupervised Robotaxi and Walked the Cybercab Line $TSLA, $GOOGL, $UBER, $AMZN, $KDK https://t.co/ks2RE2wR0r
Tech Beats Analysts: Infrastructure Ready to Disrupt Finance
Anthropic drops financial analysis capabilities Analyst job postings don't change Yet. The lag between technological capability and institutional adaptation is where fortunes hide Someone's building the infrastructure to replace these roles right now
Deep Customer Success Unlocks Upsell Even After Layoffs
I still think about one of the smallest deals we won, that I was FIRED UP about. I got credit for $5.8K. One of my most proud wins of 2024. 90 days prior, we learned the sad news an active customer...
AI-Fueled SaaS Leaders Outpace Industry Growth
SaaS growth - a few companies are accelerating. This chart ranks public SaaS companies by NTM revenue growth estimates, and the distribution tells an important story about where the industry stands today. The fastest projected growers include: $PLTR (+62%) $APP (+38%) $ZETA (+35%) $FIG and $NET...
High ROAS May Mask Lack of New Customers
Strong ROAS in Ads Manager doesn't mean you're acquiring new customers. You might just be really good at selling to repeat customers. We killed a campaign last month because of exactly this. The campaign looked clean. • ROAS was holding • Conversions were consistent •...
AI Dilutes Thought, Restoring Value to Human Speech
When Writing Becomes Detached From Thought 📌AI weakens writing as proof of thought. 📌Words can look wise without a mind behind them. 📌Human speech may regain value as thought made visible. https://t.co/XebP7NKNXe
Starlink Dominates D2D; Terrestrial Networks Still Superior
Good to see the #cluelesscult finally acknowledging that my Feb 2023 predictions that 1) Starlink would dominate the D2D market and 2) D2D performance will never match terrestrial networks were both totally correct...
Meta's Actions Spark Alabama's Push to Ban Solar
How Meta Made Alabama So Mad It’s Threatening to Ban Solar #energysky -- via Heatmap News https://t.co/oIwyZX7bZE https://t.co/9yN0C2ZnNA
U.S. Bans Efficient Direct‑drive Elevators, Unlike the World
Fact the U.S. doesn’t allow direct drive elevators (where they’re powered by two motors connected to the cab, as opposed to a cable or hydraulic system) is completely stupid. They’re faster, as safe, take less space, and a lot cheaper....
AI Model-Making Has Higher Entry Barriers Than Expected
Barriers to entry in the AI model-making industry might be a lot higher than I assumed (or than @jasonfurman has assumed)!
AI Models Exhibit Sycophancy, Agreeing 50%
Researchers tested 11 AI models and found something disturbing: AI agrees with you 50% more than a human would. Even when you're wrong. Even when your idea is terrible. It's called sycophancy. And it's not a bug. It's how they're trained.
Chip Design Shifts to Modular Chiplets as Scaling Stalls
Transistor scaling is hitting thermal and cost ceilings, pushing chip design toward modular chiplets connected by high-speed links. With shared substrates and tailored process nodes, we manage heat and sustain performance without relying on miniaturization. Microblog @antgrasso https://t.co/wKNFiV5Eio
Design AI with Human-in-the-Loop and Explainability From Day One
The hardest part of deploying AI is deciding where humans stay in the loop, when agents act autonomously, and how you prove decisions were trustworthy. Architects must design for observability and explainability from day one. #AI https://t.co/7dcoLIKa0K
Google's Extra Incentives
Not quite that simple. Could be other factors at play. Google gave me a $100 coupon, $100 store credit, and elevated trade-in for a prior Pixel. (Pixel is my “project” phone.)
Anthropic Invests $100M in Claude Partner Network
Anthropic invests $100 million into the Claude Partner Network Free + Certification program Cloud- AWS, Google, Msft Accenture, Deloitte, Cognizant, Infosys https://t.co/01kpyXrm0W
Rubin Era Will Accelerate AI Innovation Exponentially
$NVDA Blackwell era ushered in Opus 4.6, Perplexity Computer, ChatGPT 5.4. Imagine what the Rubin era brings us? The pace of innovation and disruption will continue to accelerate at an exponential rate. 👏🏻🚀 https://t.co/C3mN3kDDOH
IPhone's Power Outshines Apollo, Yet Misused Daily
The computational power in your iPhone is >100 million times more powerful than the computers that landed Apollo 11 on the Moon. And yet, most people use it primarily to argue with strangers on the internet. The future's already here—we just...
Essential 2026 AI Agent Guide for CIOs
RT If AI agents are on your 2026 roadmap, this definitive guide to 50+ enterprise agents (what they do, where they fit) is a must‑read for CIOs and CDOs. #AI #CIO @Star_CIO https://t.co/jLE8sizbgZ
From SaaS to RaaS: Pricing Shifts Toward Outcomes
Most companies still sell software. The future pays for outcomes. SaaS pricing is shifting through three phases. And if you’re not explicit about which phase you compete in, someone else will decide for you. Phase 1: SaaS You sell a...
Ahrefs Launches Free API Access for All Plans
Holy ship. 🚢 Genuinely never thought Ahrefs would do this. API access is now available on all plans. No extra fees. 🥳 It's something I always wanted as a customer, and I had no involvement in this going live, so my surprise...
From SKOs to Pickleball: Reviving Human Sales Skills
I spent the first 3 months of this year doing SKOs/keynotes for SDR/AE teams. Now that the seasons is over here is my focus is for the next season. 1. Pickleball Yeah we're back. I thought this was going to be the...
Build End‑to‑End ML with AWS: Glue to SageMaker
A real AWS Data Science pipeline looks like this: Raw data → S3 ETL → AWS Glue Query → Athena Training → SageMaker Deployment → Endpoints Monitoring → CloudWatch Add streaming with Kinesis and orchestration with Step Functions, and you have a full production ML platform. This is...
Video‑trained Robots Achieve Ten‑fold Faster Control
What if robots learned from watching videos instead of being programmed? That's the bet Rhoda AI just made with $450 million. Most robot companies teach machines "what things are." They use vision-language models trained on internet images and text, then fine-tune...
Self‑thinking Needed Before genAI; Missed It? Good Luck
The time to learn how to think for yourself was before genAI, if you missed your chance, good luck
Consistent, Genuine Reddit Engagement Builds B2B Trust
The B2B brands winning on Reddit are not spamming links. They are showing up consistently. Answering questions genuinely. Building credibility post by post. Then when someone asks what tool to use or what agency to hire, their name is already in...
AI Must Enhance Data, Not Just Depend on It
Is AI enabling better data, or do you need better data for AI? It's a classic chicken-and-egg scenario. How does AI truly improve the data itself, rather than relying on it? #AI #DataScience https://t.co/bjxDoIQgiy
German Minister Calls for Renewable Surge to Secure Energy
German environment minister urges a boost in renewables to aid energy security https://t.co/WYDxuC0GLW via @IsoldeMacdonogh https://t.co/5zqqXbdRMt
Revenue Follows Quality, Not the Other Way Around
I realized I don't care about my revenue now.💸 Not because money doesn't matter. But because revenue is just a consequence. What I actually care about: - Did our students get a job after the course? - Did they build something real? - Did they message...
Windows on Mac Makes macOS Redundant?
I remember when Windows on a Mac was first available from Apple many said it would be the end of macOS. You could now run Windows on a nice machine. Why bother running anything but Windows.
AI Base Model Race Splits Winners From Struggling Rivals
winners/losers starting to emerge after several hundred BILLION dropped on the AI base model race: WINNING: -OpenAI (first mover, but losing market share fast...) -Anthropic (Claude has taken off...) -Google (best fully integrated approach) -Amazon (AWS bedrock, training chips, own models...) LOSING -xAI (lost key founders;...
Guardian, FT Push AI Copyright Half‑truths for Profit
Guardian and FT really going hard on the half truths in relation to the AI copyright debate today There is a serious conflict of interest in advocating for policy that would directly benefit their publications at the expense of giving the...
Gemini Fails Live URL Access, Hallucinates Links
My experience with @GeminiApp is that it cannot go to live urls and despite my zero- hallucination rule invents urls. I can't figure out how to stop that. @claudeai is more reliable. Have you experienced this? What Gemini said: Here is the...
Grumpy IT Head May Stall Copilot Cowork Adoption
Anyone got access to Copilot Cowork yet? I think the biggest hurdle for adoption of Cowork will be the grumpy head of IT.
First Human Age‑Reversal Trial Targets Whole‑Body Reset
The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to...
AI's Rise in Filmmaking Sparks Authorship Debate
AI is becoming part of the filmmaking process. As the Oscars approach, Hollywood is confronting how quickly AI tools are moving into areas like script development, visual effects and post-production. The discussion is no longer whether AI will influence movies, but...
Embedding AI in Mundane Sectors Drives Massive Profits
The most profitable AI companies right now? Nobody's talking about them. One processes $1T in loans. Another grew revenue 57% in physical security. They didn't sell "AI." They embedded it into boring businesses. That's the pattern that prints money. https://t.co/nsdRWNoAG0
One Clear CTA Beats Multiple Options Every Time
I've tested 100+ landing pages. Here's the pattern: Pages with a single clear call-to-action converted at 10%. Pages with multiple CTAs converted at 1%. Your assumption that you need to give people options is wrong. Give them one clear path....
Hyperscalers Dominate AI Cloud, Leaving Small Rivals Stranded
Amazon's e-commerce scale is proven, but the AI and cloud race is a whole new game. Hyperscalers like AWS, Azure, and Google, powered by NVIDIA, have immense economies of scale. It's nearly impossible for smaller players to compete. #AI #CloudComputing...
Chinese Ceramic Endures 3272°F, Transforming Space Heat Shields
#WhatsNext? Scientists in China created ceramics that survive 3272°F, 1800°C! Could revolutionize how heat shields are used by spacecraft. (Engineering Post) #NewMaterials https://t.co/Wr6wLsUfxe
Drones Revolutionize Wildfire Fighting, Saving Firefighters' Lives
𝗙𝗶𝗿𝗲𝗳𝗶𝗴𝗵𝘁𝗶𝗻𝗴 𝗶𝘀 𝗴𝗼𝗶𝗻𝗴 𝗮𝗶𝗿𝗯𝗼𝗿𝗻𝗲. 🚁🔥 I’ve been following how robotics is entering emergency response, and drones are starting to change the way wildfires are fought. Instead of sending crews directly into dangerous areas, drones can now: → reach hotspots much faster → drop water...