Wednesday, March 11, 2026
Daily Update for People Who Love Biohacking

Estrogen may shield premenopausal women from hypertension, new model shows
Women entering perimenopause and postmenopause have a heightened risk, with about 41% developing high blood pressure after menopause. A mathematical model published in Mathematical Biosciences indicates estrogen’s vasodilatory effect is the primary protective mechanism in premenopausal women. The model also suggests that common antihypertensive drugs could compensate for reduced estrogen after menopause.
Researchers may have discovered a new way to diagnose and treat major depression at the earliest stage of the condition, giving patients the best opportunity for recovery. The research is published in Translational Psychiatry.
Medical Xpress
The effects of spinal cord injuries are complex and multifaceted. People lose not only the ability to control the movement of their limbs, but also the ability to receive sensory feedback from them. Both are critical to generate the coordinated movement involved in walking.
Medical Xpress

Posture and daily habits shape long-term health, revealing that small adjustments in the mouth can have outsized effects on overall vitality. For most people, oral health is something they think about for two minutes in the morning and two minutes at night. Brush. Rinse. Maybe floss if you’re feeling virtuous. But what if the mouth […] The post The mouth-body connection: why oral health matters for longevity appeared first on Longevity.Technology.
Longevity.Technology
Researchers at the University of California, Irvine Joe C. Wen School of Population & Public Health have identified how the hormone asprosin influences long-term weight change among postmenopausal women in the United States. The findings suggest that the fasting-induced hormone may play a significant role in shaping body composition and long-term weight stability, offering a promising target for tailored obesity prevention strategies.
Medical Xpress
A collaboration between the Wharton Neuroscience Initiative and Slalom explores how aligning work with individuals’ biological rhythms can help teams perform their best.…Read More
Wharton Knowledge

Study shows nearly half of weight loss participants reduced alcohol use after starting anti-obesity medication (GLP-1 agonists, metformin, naltrexone). https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2827069 https://www.gatlan.com/ @GatlanHealth
Using the sauna after aerobic exercise improves VO₂ max more than training alone. People who performed 30 minutes of cycling and then sat in a sauna for ~15 minutes afterward saw greater gains in their VO₂ max after 8 weeks of training compared to those who did the workout without sauna. There’s also emerging evidence for strength training, with studies showing greater increases in markers of anabolic signaling associated with muscle growth with post-exercise heat exposure. The sauna has several health benefits. But it's also a powerful tool to amplify the body's adaptations to both endurance and strength training. Clip from my recent appearance on @ThomasDeLauer