Raw Peptides Degrade Instantly, Never Achieve Effect
Hi @MartinShkreli - if as you say at https://t.co/qJh2vgV0Wm that "raw peptides have a half-life measured in seconds or minutes, meaning your body destroys them almost instantly after you inject them. They never get a chance to do anything."...
Get VZV Tested, Then Vaccinate for Shingles or Chickenpox
Ask your doctor for a Chicken Pox VZV test. If you're positive, the shingles vaccine is the next step. If you've never been exposed, you can get a chickenpox vaccine, which is safe for adults, too
NTLA Set to Unveil First In‑Vivo CRISPR Phase 3 Data
Here is a video of me entering my office tomorrow knowing that $NTLA is about to present the first-ever Phase 3 data of an In Vivo (!) CRISPR Gene Editing Program. Somehow - and after @adamfeuerstein’s🧵👇- I have a feeling...
CEO Turns Medicare Disruption Into $3B Valuation
“I am one of the most hated people in the industry." Chapter CEO Cobi Blumenfeld-Gantz is on a mission to save seniors thousands on their healthcare. That makes him a target for legacy Medicare providers. But business is booming, with $100M in...
Awake Colonoscopy Reveals Unbearable Pain at Flexures
A 69-year-old family physician walked into his colleague's endoscopy suite and asked for a colonoscopy with zero medication. No Versed. No Demerol. No Propofol. He stayed awake for the entire procedure and described what he felt at each anatomic landmark. ...
Shingles Vaccine Boosts Longevity for Over‑50s
Done. Herpes virus neutralized 🦠 Not taking any chances with my longevity, now that shingles is associated with faster aging (though not yet a known cause). If you’re 50+, consider it. The shot will likely be money- & pain-free I even...
Low Testosterone May Drain Energy—Try Oral TRT
Low testosterone might be causing your energy and mood issues. If you want to try testosterone, I recommend my Oral Testosterone Replacement Therapy from @thrivebetterrx. Oral TRT supports strength, stamina, and sexual performance, and with Thrive, your treatment is guided...
AI's Role in Extending Human Healthspan
My interview on healthspan and AI with @mmlederman1 and @LCalabreseDO @paijournal transcript video https://t.co/cRGtTIN1EN https://t.co/soUWAuPU02
Insurers Profit by Paying Claims, Not Denying Them
Few people understand: Health insurance companies make most of their profit by paying claims, not by denying them.
Your Website Is the First Trust Test
I ran Kaiser’s public site through https://t.co/f9IW600hsB. Healthcare example. Every exec should care. Your website is not “just a website” anymore. It is the first meeting. The first pitch. The first trust test. The first reason someone stays — or leaves. Pretty is nice. Clear is money.
Combat Smoke Inhalation Triggers Neuroinflammation, Threatening Brain Health
The impact of military occupational combustion smoke inhalation on neuroinflammation and brain health https://t.co/uMsiMyonkA https://t.co/3nXZ7etBPs
AI in Healthcare Needs Proof, Not More FDA Oversight
An editorial by @HashemZikry @latimes @counselheatlh calling for more regulation of AI for patient use. Yes, there is "the staggering weight of unmet medical need," 1/3 Americans are using it to "diagnose symptoms and direct care," and states are moving...
Teen Vaping Quit Attempts Double Post-2019 Anti‑Vaping Campaigns
Teen vaping quit attempts nearly doubled after 2019, coinciding with widespread anti-vaping campaigns and extensive news coverage of lung injuries, marking a significant shift in adolescent vaping behavior in the United States. publichealth
Sanofi's Dividend Streak Faces Dupixent Patent Cliff
A few weeks ago I published my deep dive on 🇫🇷 Sanofi $EPA:SAN 32 consecutive years of dividend growth. A true European Dividend Aristocrat 💪 Currently their main blockbuster Dupixent accounts for 36% of revenue, and compound patent protection expires in 2031....
Midlife Fitness Proven to Boost Longevity and Health Span
A new JACC study from the Cooper Institute (April 22, 2026) followed nearly 25,000 adults for 30 years. As a medical school professor, I teach that the strongest longevity drug we have is not on a prescription pad. This study makes...
Exploring Germany's Emerging Biotech Hubs in Tübingen and Heidelberg
All this week, I'm in Germany checking out the biotech scene in a couple of university towns: Tübingen and Heidelberg. Tune in.
BMI Alone Misses Long‑term Heart Risk, Study Shows
A new Mass General Brigham study of 136,498 adults rewrites how we should screen cardiovascular risk. As a medical school professor, I teach that one lab number rarely tells the long-term story. This study (PLOS One, April 2026) shows the same...
Nesprin‑2 Protein Blocks Heart Cancer, May Aid Other Tumors
Wondered why we don’t hear about heart cancer? Contraction-sensing Nesprin-2 protein is discovered to prevent heart cancer By causing cells to pulse (or adding in Nespirin) we might be able to treat cancer in other organs 👏 @ScienceMagazine https://t.co/A8fOuw31N2
Consumer Biotech Poised to Dominate, Telehealth Captures Value
I’ve said this before: I believe consumer biotech will become the most compelling sub-sector within biotech - without question - and one of the most attractive investment opportunities overall. At its core, this category targets products that slow or reverse aging,...
US Leverages HIV Aid for Zambian Mineral Access
Trump and Elon Musk destroyed most of the global H.I.V. program that saved hundreds of thousands of lives in Zambia. Now the US is threatening to cut remaining support, unless Zambia gives access to the country’s mineral resources. https://t.co/AnLnhEMA1E
H. Pylori and T. Gondii Infections Accelerate Frailty in Aging
Associations of common infections with frailty and mortality in two UK cohort studies "Our results indicate that infection with H. pylori and T. gondii, and the combined burden of infection may detrimentally impact ageing health. These pathogens may warrant targeting beyond...
Patients Can’t Skip Taper; Doctors Must Restart Low Dose
“Doctor, I dah pernah ambik Mounjaro sampai 7.5mg — tapi that was 1 month ago. I nak continue that dose.” “Unfortunately, tak boleh… kena start balik 2.5mg.” “Why? I taknak buang duit I.” This is actually a VERY common us doctors see during...
Continuous-Flow VADs Revolutionize Bridge-to-Transplant Care
Bridging to Transplant: Continuous-Flow VADs Changing Cardiac Care by @Doctors__squad #HealthTech #Innovation #EmergingTech #Tech #Technology #TechForGood https://t.co/JPcFWLKViP
Doctors Warn DIY Peptide Injections Cause Serious Injuries
People are injecting DIY peptides for weight loss and longevity. Doctors are alarmed at the side effects. “Doctors working on the bleeding edge of longevity care in high-end clinics around the globe — from concierge practices in wealthy enclaves of California...
Anecdotes Aren’t Data: Call for Rigorous Rapamycin Trials
Table updates worth noting 🔎 🔘 @bryan_johnson stopped it 🔘Alan Green died at 80 from hereditary cardiomyopathy 🫀 🔘Misha Blagosklonny died at 63 from cancer 👉These are cases, not data. Instead of adjusting the tally, what we actually need are rigorous human trials. Is rapamycin...
Debunking Pseudoscience Hurts MAHA's Profit From Overpriced Treatments
So MAHA is not happy that by debunking their pseudoscience, I hurt the sales of their ivermectin, hydroxychloroquine, fenbendazole, which they purchase in bulk, repackage, and sell to you after they jack up the price or pair it with an...
10‑hour Pill Camera Finds No Abnormalities, Next Endoscopy Scheduled
This pill camera traveled my intestinal tract for 10 hrs and 38 min, taking 33,537 images. Looking for lymphoma, Crohn's ulcerations, small bowel cancer, diverticula, and polyps. Nothing found. This was Jan 2022. Bidirectional endoscopy next week. Upper and lower....
Integrating Affordable Housing Into Healthy Aging Care
Great panel insight from Jon Warner, Neelam Brar and Andrew Smith, NHA, M.Ed., PMP #aging #care #healthyaging #affordablehousing https://t.co/dALbZrykhW
Russian Gene Therapy Claims to Extend Life to 150
Russian scientist in bombshell ageing drug claim after Putin discussed 'living to 150' The Russian gene-therapy treatment could benefit Putin and his inner circle. https://t.co/dunqBJEPxN https://t.co/sH2GNbRqSs
Russia Claims Progress on 150‑year Human Lifespan Plan
Vladimir Putin's plan to make humans live for 150 years is in process under supervision of Russian scientists 🔎 “ Denis Sekirinsky, a Russian science and education minister, claimed his country's researchers are on course…” https://t.co/tVx2REdovu https://t.co/1WCXvDFWnf
Family Values Can Seed Physician Burnout Before Practice
Physician burnout is often inherited before it is experienced. Amna Shabbir, MD, an internal medicine physician and geriatrician, traces her own burnout not to medical school, residency, or the pandemic, but to the year she was born. Her mother was...
Nanophotonic Chips Finally Make the Proteome Visible
We sequence genomes and map transcriptomes with ease. Why is the proteome still invisible? Proteins are where biology actually happens. But until now, we have lacked the tools to read them at scale. @jendionne and her team are building nanophotonic chips that...
Every 1,000 Steps Cuts Mortality Risk by 15%
The association between daily step count and all-cause and cardiovascular mortality: a meta-analysis A 1000-step increment was associated with a 15% decreased risk of all-cause mortality... with significant benefits starting event at 2500/4000 steps/day. https://t.co/8d6VGnP0Dg https://t.co/f9h0D5dWlV
Wealth Boosts Health Spending, Not Necessarily Health Outcomes
Two important takeaways: 1. Health care is a superior good. As a country becomes richer, it will choose to spend more on health. 2. This tells you nothing about outcomes/efficiency. A country may spend a lot & still not get as high...
Mike Rockefeller's Podcast Democratizes Elite Healthcare Investment Insight
Super awesome that one of the most respected active healthcare investors, Mike Rockefeller (Co-CIO at Woodline and formerly a top Citadel PM) started a podcast interviewing healthcare CEOs. When I was a PM, I would occasionally share group meetings with Mike,...
Kidney Decline Skews Neurodegenerative Biomarker Levels; Ratios Help
Influence of Decreased Kidney Function on Plasma Biomarkers of Neurodegenerative Disorders in Routine Care: Confirmation of the Interest of Ratios https://t.co/5TCkkyDxkM
PBMs' Formulary Tactics Drive Billion‑Dollar Patient Costs
The same companies you say are denying claims, are the ones you prop up buying access to formularies. Tell your members to stop being afraid of the PBMs and the insurance companies that own them, or they own. Your...
Unified AI Healthcare Regulation Accelerates Patient Access
"50 competing standards cannot be the answer for a technology this consequential... many assume that regulation slows down transformative technology, but history suggests otherwise." Great piece by @HashemZikry calling for consistent regulatory guidance to **improve**, not impede, the solving of...
Thyroid Hormones Correlate
Associations of Thyroid Hormones and Resting Heart Rate in Patients Referred to Coronary Angiography https://t.co/aOvAW52tQ6
Influenza Pioneer Nancy Cox Passes, Legacy in Global Surveillance
The world of influenza science has lost one of its giants. Nancy Cox, who led #CDC's flu division for years & worked assiduously to improve global flu surveillance, died Thursday. I learned a ton from Nancy Cox. RIP. https://t.co/vNBuYpFSpU
Doctors Won't Be Replaced: Embrace Blended Intelligence
“Will AI replace doctors?” I hear this question a lot, but I think the answer is no. AI is amazing at pattern recognition. But medicine is also about judgment, context, human connection. That’s on us. The future is "Blended Intelligence,"...
Seeking Tools to Boost Post-Stroke Short-Term Memory
#gamers #cognitive #neurology Can you suggest anything to help my friend Brenda @bsuecannon? She wants to buy s/thing to help her husband improve his ST memory that was impaired from a recent #stroke. Thx.
GLP‑1 Drugs May Trigger New Restrictive Eating Disorders
"There is also compelling preliminary evidence suggesting that the use of these drugs [GLP-1] could exacerbate and lead to new diagnoses of restrictive eating disorders, including anorexia nervosa." @NEJM today https://t.co/PeTLgyRXiL
GLP‑1 Weight Loss Drugs Lower HRV, Raise Heart Rate
Reducing body weight with GLP-1 agonists isn't a free lunch: negative impacts on HRV, RHR GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons https://t.co/4QNy141TtK
NVO Shows Fewer AEs; LLY Wins on Lower COGS
The $NVO drug has fewer AEs (based on comparative discontinuation rates) - only real advantage $LLY has here is much lower COGS (small molecule vs poorly absorbed peptide).
Aid Cuts Spark HIV Resurgence and Human Cost
HIV now returning. This carefully details the system breakdowns after aid cuts, the local actions for resilience, what still had to be sacrificed, then the human consequences. https://t.co/RUspAMsUm8
APOE4 Raises Alzheimer Risk, but Lifestyle Can Shift Outcomes
APOE Status and Dementia Risk... APOE4 is the strongest common genetic risk factor for late-onset Alzheimer's. About 25% of the population carries at least one copy. It's a risk modifier... not a guarantee. And the levers that change the trajectory are...
Tzu Chi Hospital Poised to Be First Mars Medical Center
Should humans ever relocate and settle on Mars, @tzuchihospital.ind would be among the very first hospitals to open there, @nasa.
Advanced Biotech Diagnostics Enable Precise Disease Detection
Accurate Disease Detection with Advanced Biotech Diagnostics by @antgrasso #MedTech #Healthcare #HealthTech #Tech #TechForGood https://t.co/nQIkC2nuzM
Trump Leveraged HIV Aid for Rare Mineral Extraction
What he was protesting was Trump using PEPFAR to force countries to give up rare minerals in exchange for HIV drugs. There is no bottom.