Alleged FDA Pressure Removes Study Confirming Long‑term Vaccine Efficacy
Vinay Prasad forced FDA scientists to withdraw a paper from Vaccine, the journal I am co-EIC of, because it showed that COVID vaccines work for everyone 6 months+. This is Gold Standard Science at Marty Makary’s FDA. Setting the Gold Standard in corruption & graft
CAR‑T Turnaround: Kelonia’s LLY Deal Signals New Pharma Play
A VERY SPIRITED interview w/ Venrock VC Bryan Roberts re: Kelonia Therapeutics and its $LLY deal on this week's Readout LOUD podcast. A CAR-T biotech’s dramatic turnaround, and drugmakers’ tactics to drive more scripts https://t.co/600DsE1cBm via @statnews
NIH Director Censors Routine Vaccine Study Over Personal Dislike
To be clear: @NIHDirector_Jay reportedly took issue with the study design, which is routine for evaluating vaccines post-market. Podcast Jay, who has no expertise in vaccine trials, decided unilaterally he didn’t like it & thus censored results of studies our...
Bioethicist Vs. Germline Editing Entrepreneur Sparks Uneven Debate
Starting right now. Debate between I. Glenn Cohen (Harvard/reprogenetic bioethics) vs. Cathy Tie, 'serial' human germline editing startup entrepreneur. This should not be an fair fight, but Glenn Cohen is a nice guy...so https://t.co/qfqivoLvhV
Metformin Fails to Boost Walking Distance in PAD Patients
Metformin to Improve Walking Performance in Lower Extremity Peripheral Artery Disease: The PERMET Randomized Clinical Trial "Among people with PAD without diabetes, metformin did not improve 6-minute walk distance at 6-month follow-up compared with placebo. These results do not support metformin...
Trump’s Drug Pricing Deals Underdeliver on Promised Cuts
Trump celebrated closing the first round of 17 drug pricing deals, now looking ahead to many more. But the reality of the deals, so far, have fallen short of grand promises the president made. https://t.co/QmhvZNgNyI
All RFK Jr. Hearings Summarized, Plus Fix‑It Discussion
On this week's #WTHealth podcast: we watched ALL the RFKjr hearings so you didn't have to! with @SherylNYT, @AliceOllstein, and @victoriaregisk. Plus "How Would You Fix it?" with David Blumenthal. https://t.co/YpCpbgcSVC
FDA Approves First Free Gene Therapy Restoring Deaf Children's Hearing
JUST IN: FDA approves first ever gene therapy that restores hearing in children born deaf, with treatment available at no cost
Healthcare Software Shifts From Workflows to Intent
Healthcare software is moving from workflows… to intent. Srinivas Velamoor talks about systems that understand what you want, not just what you click ↓ https://t.co/iGlc6onYkI @NextGen #AmbulatoryEHR #HITSM https://t.co/0h8tr7GxkZ
Fertility Clinics Sell IVF; Seek Holistic Care Elsewhere
Every week I talk to couples who are struggling to conceive. They come to us because they feel completely lost and in the dark about their own fertility. And almost all of them have the same story. They went to...
Profit Gap: Preventing Strokes Beats Treating Them
Is there a window in American healthcare where preventing strokes is more profitable than treating them? @Farzad_MD left his dream job at the HHS to find out. New Lifers this week: Spotify: https://t.co/sl8a6nuUlC Apple: https://t.co/yDarYoJcDz Youtube: https://t.co/UDbEjHA3cD

Doctors Are Prescribing Social Connections to Boost Health
Take a walk with friends twice a week. That’s an example of a prescription your doctor might write for you in the future. @NatalieDaher7 reports in @axios on the rise of social prescribing: doctors sending patients to social experiences. It makes sense:...

Obese HFpEF Patients Show Sarcom
In people with HFpEF (heart failure with preserved ejection fraction) and severe obesity, there is a heart muscle cell defect with sarcomere hyper-phosphorylation. Besides weight loss, sarcomere enhancers (not yet studied) may help. @ScienceMagazine https://t.co/or9VaPjD8J https://t.co/FG98KIzIfN
Charge Masters Are Fake Prices Exploiting Patients for Profit
Gotta make charge masters real prices or get rid of them. The CM is like WAC in pharma. It's a made up number that abuses the uninsured , those in their deductible phase, and those who need...

AI-Driven Synthetic Evolution Accelerates Biological Design
Evolution is the most powerful optimization algorithm ever run. It just takes billions of years. Researchers are now rewriting the code. #SynBioBeta2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here:...
Regeneron Approves Free Gene Therapy, Sparks Industry Precedent Worries
$REGN wins FDA approval for its gene therapy to treat a very rare genetic form of hearing loss. The company is giving away the therapy for free. OTOF-related hearing loss affects approx. 50 newborns per year, so really rare, but......

Medical Training Must Evolve Faster than Technology
The future of medicine is arriving faster than our training models are evolving. A student starting medical school in 2026 won’t earn their M.D. until 2030, and likely won’t finish residency or practice independently until 2033 or beyond. By then, the...
Affordable Housing Serves as Unrecognized Care Coordination Hub
This is a really important reframing. Affordable housing operators are already acting as de facto care coordinators, but without the infrastructure, funding, or recognition that #healthcare systems receive. https://t.co/NIe4JUGjLe
Roche Bets on Cancer and Obesity Drugs Amid Biosimilar Pressure
Roche, facing biosimilar threats, puts faith in new cancer and obesity drugs https://t.co/IIt0INA9sI @ByJonGardner $RHHBY

New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor
EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/n2tSuJXS5b

Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma
#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/VPIH8iphVP

Phase 3 Trial Tests Daratumumab Reg
.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/xv1RlCv8gl
Doctors Must Speak Up or Lose Public Influence
Brutal truth: MD/MS doctors are losing the internet to people with weekend certifications. You studied for 10–15 years. They studied lighting, scripting, and delivery. They talk confidently about gut health, hormones, heart, brain. You hv depth. They hv reach. Hot take: The biggest threat to MD/MS doctors...
Sanofi Reports Strong Sales Amid Growing R&D Pressure
Sanofi posts upbeat sales as R&D pressure builds https://t.co/4WUccjXY5D by Kristin Jensen $SNY + 2% $REGN
Amazon Teams with Grow Therapy for Employee Mental Health
Whoa... The employer behavioral health wars are heating up! Amazon is partnering with Grow Therapy on EAP. 👇 https://t.co/jVDA2xBhsE

Tech Giants Converge on AI‑Biology at SynBioBeta 2026
Silicon Valley's biggest tech players aren't just watching synthetic biology from a distance. They're showing up in person. This year at @SynBioBeta 2026, delegations from @Amazon, @Google, @Apple, @OpenAI, @Anthropic, @NVIDIA, and others are coming to San Jose to see what's...

AI Becomes Healthcare’s Operating Layer, EHR Becomes Plumbing
This is bigger than 𝗰𝗼𝗽𝗶𝗹𝗼𝘁𝘀. 🚀 OpenAI, Anthropic, and Google are racing to become the 𝗼𝗽𝗲𝗿𝗮𝘁𝗶𝗻𝗴 𝗹𝗮𝘆𝗲𝗿 above healthcare’s fragmented mess. 🏥 Once AI becomes the interface, the EHR stops being the 𝗱𝗲𝘀𝘁𝗶𝗻𝗮𝘁𝗶𝗼𝗻. 📍 It becomes the 𝗽𝗹𝘂𝗺𝗯𝗶𝗻𝗴. 💧
Gene Therapy Cures Specific Deafness—A Modern Miracle
Another modern miracle: Gene therapy cures a form of deafness. Harvard to USA: You're welcome. https://t.co/mfEzVMGugp

Implant Keeps Drug‑Producing Cells Alive for a Month
A new bioelectronic implant can support populations of three different drug-producing cells for more than a month, keeping them supplied with the correct amounts of oxygen. These cells could produce drugs to treat various cancers, autoimmune diseases like arthritis, and...

GenAI Enables Asking Right Questions, Not More Dashboards
In healthcare, we never really had a data problem. And honestly, the same is true in most industries I’ve worked in. There was 𝗯𝗹𝗲𝗻𝘁𝘆 𝗼𝗳 𝗱𝗮𝘁𝗮. Usually too much of it. 📊 Claims data. Operational data. Financial data. Customer data. Supply chain data. Workflow data. The real problem was...

RFKJ Touts “Gold Standard” Science While Ignoring Vaccine Experts
RFKJ: We are bringing back “gold standard science” AOC’s face: Then why are you ignoring all of the science around vaccines? And removing the experts from the ACIP?!
Lab‑grown Sperm Creates Embryos, Easing Dystopian Fears
Lab-grown sperm used to create embryos for the first time. Good news if you were worried about the Handmaid's Tale trajectory. https://t.co/q6gItYuGoJ
Trump Appoints Former Tobacco Exec to Top CDC Role
The Trump administration has crammed an astonishing number of political appointees into the highest echelons of #CDC, most with few or no medical or public health credentials. One of the latest is surprising: A former Big Tobacco exec. https://t.co/8jA8qfqMv6

Epic's Surgical Reply Forces Veeva Into Arbitration Trap
Epic filed their Reply in Veeva Systems v. Epic this week, closing the MTD briefing. The Reply is tight and surgical - Epic quotes Veeva's own opposition back at itself three times in the first paragraph and builds the whole...

New AHA/ACC Guidelines Redefine Heart Disease Prevention
The biggest shift in cardiovascular prevention in years just dropped — and almost no one is talking about it. As a medical school professor, I've watched heart disease stay America's #1 killer for decades. New AHA/ACC guidelines finally move the line. What...
Hims Secures GLP Deals, Positioning for Retatrutide Boom
This is massively good news for $HIMS members and $HIMS shareholders. $HIMS now selling $LLY GLPs which is Tirzepitide. $HIMS already selling the $NVO GLPs which is Semaglutide. This also means that $HIMS members should have access to Retatrutide...
Half‑million UK Medical Records Listed for Sale After Breach
Medical data of 500,000 people in UK put up for sale after data breach - https://t.co/zBa4Kbu9u3 via @FT

AI Chip Giant Outvalues Entire Global Pharma Industry
NVIDIA is now worth more than the entire Big Pharma combined on the stock market. I shared this image from Reza Zahiri, PhD, MBA, 6 months ago. NVIDIA’s market cap now hit $4.9 trillion ($0.3 trillion more than then), which...
ASCO Grants IDYA Late‑breaker Despite Extensive Prior Data
Given how much $IDYA has already released (ORR, PFS, stats, PFS curves) I'm a little surprised #ASCO26 is OK with giving it a late-breaker.

RG6735 Identified as New $RHHBY Phase‑1 Asset
Any idea what RG6735 is? Looks like a new $RHHBY code for sth that went into phase 1 earlier under a different name. https://t.co/7Cb5Ft2BWC

Sex‑disaggregated Data Crucial, yet Underused in Women's Health
Uncharted: understanding women’s health across the body Disaggregating data by sex is a powerful way to help develop better diagnostics and treatments for women — but researchers say it’s not used enough. https://t.co/7TeEYN4yPf https://t.co/95VdJKI05c
CEPI Shows Courage; Institutions Must Follow Suit
Many institutions are failing to meet the moment, but not all. @CEPIvaccines proves it has the courage & conviction to carry out essential vaccine work regardless of political pressure for complicity. I wish more institutions would follow their funder’s example.

OSK Reprogramming Restores Adult Heart Regeneration
NEW STUDY: OSK rewinds the clock and pushes adult heart cells into a regenerative state that improves heart repair Why is this such a big deal? Because adult heart cells do not meaningfully divide, which is why the heart heals with scar...
Insilico Launches First Longevity Board to Accelerate AI Aging Research
Insilico Medicine Announces Industry's First Longevity Board to Accelerate AI-Driven Aging Research for Drug Discovery https://t.co/Xd8GpDTVjW
AI Redefines Healthcare: Tools, Training, and Patient Bonds
I really enjoyed this chat with the amazing Kevin Pho (@kevinmd) about AI and healthcare. We talked about knowledge tools (ie, @EvidenceOpen), med ed, deskilling, scribes, EHRs, and the doctor-patient relationship in the Era of AI. https://t.co/rHF62fWeFN

Medical Gaslighting Isn't Malicious, But It Kills
Most medical gaslighting is not malicious. That is what makes it dangerous. Carolyn Larkin Taylor, a neurologist of 30 years, lived the textbook case. She had been seeing the same gynecologist for two decades. Postmenopausal bleeding that would not resolve....

Epidemiology Insights: Tackling Pandemic Threats with Prof Rimoin
Great to host my extraordinary colleague/friend Prof Anne Rimoin @arimoin @UCLAFSPH UCLA Fielding School of Public Health here at @TXMedCenter @BCM_TropMed @TexasChildrens discussing her important work tomorrow on epidemiological approaches to pandemic threats and public health https://t.co/mKRffWimMv
Your Body Heals Most Disc Herniations—Therapists Just Position
76.6% of lumbar disc herniations spontaneously resorb on their own. Your PT didn't cause it. Your chiro didn't cause it. The McKenzie press-ups didn't cause it. Your immune system did. Most of what gets credit for "fixing" disc herniations is just standing in...
RFK Jr. Deflects Measles
1/n Let’s recount his public statements made in 2025 when he was HHS Scty during our awful measles epidemic in Texas and how he undermined public confidence in public health, as 99 kids/adults hospitalized and 2 kids needlessly died....
CDC Suppresses COVID Vaccine Efficacy Report, Raises Transparency Concerns
There’s no more science at DHHS, just fake MAHA ideologies to benefit the corrupt health wellness industry. A modern version of Lysenko Communism. It’s now up to a patchwork of state govts/NGOs. With no crisis we’ll survive, but if a...