OpenAI Releases Free ChatGPT for US Clinicians
. @OpenAI launches ChatGPT for Clinicians Designed to support clinical tasks like documentation and medical research… Free for any verified physician, NP, PA, or pharmacist, starting in the U.S. https://t.co/IHah1binWV https://t.co/jbGnm0GVFC
Shingles Vaccine Cuts Dementia Risk by Half.
Have you had your shingles shot? A major 2026 study of over 300,000 people age 65 and older found that the shingles vaccine reduces the risk of dementia by up to 50%. Remarkably, men, women, and folks across age and ethnic...
Fenebrutinib Shows Promise, Yet Safety Concerns Loom
Relevant to $TGTX was the Roche $RHHBY fenebrutinib trial results recently announced. Excellent efficacy, but two cases of Hy's Law. Both resolved, but a patient might not be so lucky next time. Hard for me to see this gaining widespread...
TGTX Shows Consistently Low Relapse Rates Across Trials
This very low relapse rate in this $TGTX Phase IV observational trial is consistent with that seen in their 6-year extension study: https://t.co/Shvb8h8VRr
Intense Exercise Boosts Belief, Cuts Depression and Anxiety
Physical Activity and Mental Health of Employed Adults: Mediation and Moderation Effects of Beliefs in the Benefits of Physical Activity “more intensive PA was related to a stronger belief in PA benefits, subsequently leading to reduced levels of depression and anxiety.” https://t.co/JBF1kDolZa
POTUS Pushes Zero‑tolerance on Fentanyl, Lenient Cannabis Reclassification
Reclassification is critical so that we can have a no-tolerance rule for fentanyl and meth, which are deadly, and a reasonable policy on plant medicine and cannabis — which experts believe are far less harmful (and in therapeutic or hospice...
Paxlovid Showed No Hospitalization Benefit in Vaccinated Seniors
In 2 randomized, open-label trials of Paxlovid there was lack of evidence of reduced hospitalizations among the participants, who were age 50+ with coexisting conditions, and who were vaccinated. The endpoint was very low (<1.2%) in the treatment and control...
Affordable Telemedicine Solutions Ease Staffing and Budget Strains
Staffing shortages + tight budgets = tough decisions. Telemedicine can help—if you choose the right platform. We break down budget-friendly options hospitals are actually using. 👇 https://t.co/rCm5j8wrKg @telespecialists @VSee @TeladocHealth @TeleMed2u @EagleTelemed #HITSM
COVID Vaccine Halved ER Visits, Hospitalizations for Healthy Adults
The report - that CDC leadership blocked after clearing scientific review - showed the COVID vaccine cut ER visits and hospitalizations for healthy adults by 1/2 last winter. It followed widely used methods, incl in a CDC flu report last...
25% Beta‑Cell Loss and Aging Drive Type 2 Diabetes
Researchers analyzed ~250,000 pancreatic islet cells and found that in type 2 diabetes, about 25% of insulin-producing beta cells are lost and many of the remaining ones become aged and dysfunctional. They identified dozens of genes—along with pathways like vitamin...
Alzheimer's Drugs Show Minimal Benefit, Review Reveals Deeper Issues
Alzheimer’s drugs offer little benefit, major review finds – and the reasons go deeper than the science https://t.co/cnMPAEQumY https://t.co/wtg8llquON
FDA Criticizes Replimune's Melanoma Trial Design
Some observers, including @US_FDA, have criticized @Replimune for the design of the trial that led to the decision not to grant accelerated approval of their melanoma treatment. I asked the company's Chairman about that view. Watch the full interview: https://t.co/XYVmSeodLv https://t.co/OO8eXTZOXh
Zepbound Sparks Diet Shift, Slashes LDL by One‑third
Patient started Zepbound and cut their LDL cholesterol essentially by a third and no longer in the range to start a cholesterol medicine. The medicine doesn't lower LDL cholesterol that much, but it did allow her to eat a more plant-forward...
Social Support Beats Policy‑blind Trauma Treatment for Recovery
Treating trauma while ignoring the social and political conditions that generate it risks turning medicine into a repair shop for problems our policies continue to produce. The strongest predictor of sustained recovery from addiction is social support. https://t.co/HoXy8efgWf
Pharma-Backed Petition Urges FDA to Overhaul Rejection Letters
New Pharma-backed petition calls on FDA to reform how it releases drug rejection letters, says current process is unlawful - https://t.co/XLwCxt1FY6
Omada Adds Continuous Support to GLP‑1 Prescriptions
Too many GLP-1 patients get only a script, and not a strategy. @OmadaHealth is changing that by pairing GLP-1 prescribing with continuous, between-visit support from day one through discontinuation. Learn more: https://t.co/crIf2pMtCK https://t.co/N9Rrxq1RFD
PK/PD Crucial for Next-Gen ADC Development
Wonderful tour de force on ADCs by @raffcolo highlighting the importance of PK/PD going forward with new formats https://t.co/nUpBNNoVil
Accepting Loveland Foundation Vouchers for California Therapy
For the girlies that have/ use @thelovelandfoundation vouchers, I am accept the vouchers for therapy in CA. Reach out if you are looking for a therapist ✨
Moderna Launches mRNA Bird Flu Trial After Funding Loss
Moderna, after losing US funding, rebounds to start mRNA bird flu vaccine trial https://t.co/cKyC9jfWAj by Kristin Jensen $MRNA
Secure, Connected Health Systems Need APIs, Identity, Testing
APIs, identity, patient matching, data sharing trends, and bold ideas like routine EHR downtime testing—so many smart points in one place. Thinking about how to build more trustworthy, secure, and connected systems? ⬇️ 🔗 https://t.co/rzpgNz6fqO @DirectTrustorg #Interop #HITSM
Prelude Tx Unveils Early-Stage KAT6A Degrader
Looking through my #aacr26 collection of posters from yesterday. Prelude Tx have a KAT6A degrader (PRT13722) in early development to compete with inhibitors: https://t.co/23zBtCX8Hs
Personalized CRISPR Poised to Become Standard Care
How individualized CRISPR genome editing can go from rare, expensive use to broader accessibility and a standard of care by @UrnovFyodor and Sadik Kassim @Nature https://t.co/ddc5ASPPAK https://t.co/GOFneIyuai
Merck Expands AI Push; Roche Reports MS Drug Data
Merck adds to pharma’s AI push; Roche details MS drug results https://t.co/VmpWyLhP9A $MRK $RHHBY $TGTX $RCUS $GILD #biotech
New Receptor Enables Bat Alphacoronavirus Entry Into Humans
Discovery of a new receptor by which alphacoronavirus from bats can get into human cells and the potential for transmission https://t.co/LE5sTVyfkS @Nature https://t.co/aszqnDMQqE @NatureNV https://t.co/ejnvrvr6BO
Private‑Equity Hospital Takeovers Cut Staff, Raise ER Deaths 13%
"When private equity firms acquire hospitals, they cut clinical staff to boost profits — and emergency room death rates rise 13%." — from INCORRUPTIBLE by Eric Ries, out May 26 https://t.co/QemqcsZZbq
Trump’s “Most‑favored‑nation” Deals Don’t Ensure Cheapest U.S. Drug
One lie worth refuting that @RobertKennedyJr keeps repeating across hours of testimony before Congress from the last week (final Senate Finance/HELP day today): The "most-favored nation" drug pricing deals that Trump crafted with 16 cos. DO NOT by any means guarantee...
Doctors Profit Millions From No Surprises Act Loopholes
The big surprise of the No Surprises Act: Doctors are cashing in on the consumer protection law, getting paid $440,000 for breast reductions and $14,000 for steroid injections. Latest investigation with @sangerkatz: https://t.co/keJwqqAeLX
Redefining ‘First‑in‑Class’ Amid Faster Competing Therapies
How do we define “first in class” when there are others further ahead? This example is from Atheron Therapeutics w/ a CCNE1 degrader #aacr26 https://t.co/s22biREUrt
Schwartz's CDC Success Hinges on Kennedy's Authority
Is Erica Schwartz a good pick for #CDC director? Experts say as long as she reports to Kennedy, it doesn't much matter. “She could be terrible, she could be great. But it’s really: What is the secretary going to allow?”...
CDC Vaccine Efficacy Report on Halved Winter Hospitalizations Shelved
The #CDC report that showed the #Covid vaccine halved the risk of a recipient needing emergency care or hospitalization this winter has been shelved by HHS, @bylenasun reports. https://t.co/tCNx8LSIKn
EMP‑01 Shows Strong Patient‑Reported Gains in Social Anxiety
What incredible news to wake up to! Some weeks ago, @ataibeckley reported positive topline results for EMP-01 (oral R-MDMA, a patent-protected version of #MDMA) for Social Anxiety Disorder(SAD). The data reported was the reduction in symptoms as reported by the treating...
Dell's Billion-Dollar Gift Positions UT as Health Hub
@MichaelDell is a true leader & visionary. "A society grows old when men plant trees whose shade they'll never sit under." We need more US boomers to step up and reinvest in their grandchildren & communities like Dell. With...
Medical AI Lacks Proof of Patient Care Benefits
On the lack of compelling evidence that medical AI is improving patient care, and what to do about it, a @NatureMedicine editorial https://t.co/kQiN6L2ai7 https://t.co/zhae0bFZ8R
AI‑Driven Discoveries Shift Medicine to Understanding the How
The Real Era of the Art of Medicine Begins with Artificial Intelligence. I mean, when AI discovers new treatments and runs in silico clinical trials that physicians, pharma companies, or medical innovators would never think of, our job will be understanding the...
CDC Withholds Report Showing Vaccines Reduce Hospitalizations
Can't hide from science. CDC won’t publish report showing covid shots cut likelihood of hospital visits https://t.co/zajDCiaaAJ
Belief in Treatment Lowers Brain Pain Activity
Simply believing you’re being treated can measurably reduce the brain’s pain processing. MRI scans across 20 studies show that placebo treatment reduces activity in pain-processing brain regions. The effect is small, but consistent. Full video on placebo: https://t.co/l1PV2LNyhA Study: PMID: 33654105
Bad Sleep Drives Depression and Insulin Resistance, Not Just Symptom
One of the most expensive mistakes in health is treating bad sleep as a side effect. Very often, it is part of the mechanism. A new study on depression and insulin resistance caught my attention. Link at the end. I will walk...
Oscar Health Turns Health Insurance Into Consumer Marketplace
Airbnb for healthcare?? Oscar Health has an interesting history. They were the first health insurance company to give clients a health tracker. If they proved through data that they lived an active life, they received benefits and rewards. As healthcare is the...
CNN Hunts Real Patient Stories on ChatGPT Health Use
It must be a milestone if CNN is actively looking for patient stories of using ChatGPT for health issues. Using generative AI is not newsworthy enough to be covered frequently. Also, there are many patient stories out there proving that...
Billionaires Drive Biotech's Race for Cancer Blockbusters
Just read "For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug" a good book about developing of a pair of cancer drugs. Great work by @nathanvardi https://t.co/rrTOe6GqIB
Blocking PGAM‑Chk1 Kills Senescent Cells, Eases Lung Fibrosis
Researchers found that senescent cells depend on a PGAM–Chk1 interaction to boost glycolysis and survive, and blocking this interaction selectively kills these cells and reduces disease effects like lung fibrosis. https://t.co/VTsHTkBcad
Durvalumab Plus FLOT Improves Resectable Gastric Cancer Outcomes
EFS in MATTERHORN: A Ph3 RCT of durvalumab plus 5-fluorouracil, leucovorin, oxaliplatin & docetaxel chemotherapy (FLOT) in resectable gastric/gastroesophageal junction cancer (GC/GEJC) - @YJanjigianMD et al. #ASCO25 LBA5 https://t.co/lW8KUtXdB3 #NCT04592913 #stcsm #esocsm
CtDNA‑guided Cam
Camizestrant + CDK4/6i for the Tx of emergent ESR1 mutations during 1L endocrine-based therapy & ahead of disease progression in Pts w/ HR+/HER2– advanced breast cancer (ABC): ...ctDNA-guided SERENA-6 trial - Turner et al. #ASCO25 LBA4 https://t.co/9jFfuGd1IS #NCT04964934 #bcsm
Rusfertide Shows Efficacy in Phase 3 PV Trial
Results from VERIFY, a phase 3, double-blind, placebo (PBO)-controlled study of rusfertide for treatment of polycythemia vera (PV) - @KuykendallMd et al. #ASCO25 LBA3 https://t.co/XID3tkj6Sk #NCT05210790 #mpnsm
Adjuvant Nivolumab Boosts Outcomes in High‑Risk HNSCC
NIVOPOSTOP (GORTEC 2018-01): Ph3 RCT of adjuvant nivolumab added to radio-chemotherapy in Pts w/ resected head & neck squamous cell carcinoma at high risk of relapse - Bourhis et al. #ASCO25 LBA2 https://t.co/Uxh4JhZyDE #NCT03576417 #hncsm #ImmunoOnc
Atezolizumab Boosts Adjuvant Therapy for dMMR Colon
RCT of standard chemotherapy +/- atezolizumab as adjuvant therapy for Pts w/ stage III deficient DNA mismatch repair (dMMR) colon cancer (@ALLIANCE_org A021502; ATOMIC) - @FASinicropeMD et al. #ASCO25 LBA1 https://t.co/cGalNPlxMe #NCT02912559 #crcsm
First Tumor NGS Usage Varies Across Top Five Cancers
Utilization and timing of first tumor next-generation sequencing testing (NGS) in Pts w/ 5 most common cancers in the USA - @chadihcmd et al. @huntsmancancer #ASCO25 Abstract 11014 https://t.co/lWefncnTb2 #PrecisionMedicine #hemonc #bcsm #crcsm #lcsm #pancsm #pcsm https://t.co/oIX8QTRD8x
Voters Ban AHF's Taxpayer-Funded Ballot Initiative Abuse
For about a decade, the AIDS Healthcare Foundation used many millions of taxpayer dollars to fund a series of ridiculous ballot initiatives reflecting their CEO's personal beefs before voters in 2024 made this illegal. You think you know how weird...
Nurix's NRX-0305 Shows
New degrader from Nurix looks interesting: NRX-0305 demonstrated antitumour activity across a wide range of Class 1 BRAF inhibitor-resistant and Class 2/3 mutant PDX models #aacr26 https://t.co/0UGF5Od2Cp
Psychedelics Could Revolutionize Psychiatry Like Microscopes Transformed Biology
“Psychedelics, used responsibly and with proper caution, would be for psychiatry what the microscope is for biology and medicine." – Stanislav Grof