Hospitals Serve All; President Delivers Nationwide Improvements
Many times I posted about the ongoing renovations at Mpilo Hospital… Your problem is thinking that hospitals are tribal or regional establishments, they are for everyone. President @edmnangagwa is DELIVERING, even NEGAHOLICS like you will appreciate one day… https://t.co/YR3ZVuiPbT
Polypharmacy and Anticholinergic Load Accelerate Aging via Inflammation
Polypharmacy, anticholinergic burden and inflammation in relation to accelerated biological ageing Note the observational design, with corresponding limitation in inference. The authors concluded: "Both polypharmacy and anticholinergic burden are associated with accelerated biological ageing, partly mediated by inflammation, including a potential serial...
China’s Rapid Dead-Virus Vaccines Match Severe-Case Protection
small point, but the record time is a bit of exaggeration. China developed two old-fashioned dead virus vaccines in roughly the same time-frame. They were less effective in preventing the original strain, but comparably effective in preventing serious illness and...
Fear Outpaces Context in Virus News Coverage
I ran sentiment analysis on top news coverage of the new virus. My conclusion: fear travels faster than context. The best public-health signal was measured. A lot of the media signal was amplified. This infographic breaks down who stayed grounded and who leaned alarm-prone. https://t.co/ZJP8ODS0Ft
Even a Bad Nurse Beats No Care at Home
No nurse is better than a bad nurse in your child’s home [PODCAST] http://dlvr.it/TSRtZy Podcast #Nursing
Paying Kidney Donors Could Save Lives and Cut Costs
Nobel laureate Al Roth has a great piece in @washingtonpost today on why we should compensate kidney donors. Kidney failure disproportionately hits Black and low-income Americans, costs Medicare $55B+/yr, and most people who need a transplant will die without one....
Zoonotic Spillovers Becoming the New Normal
Many thanks @OutFrontCNN @ErinBurnett for hosting me this evening with colleague Dr. Gustavo Palacios a hantavirus expert. I made the point that zoonotic spillover events are now occurring with increasing frequency: SARS-1 MERS, Ebola, SARS-2, H5N1, now Andes virus, a...
Nonprofit Hospital Tax Break Costs $300B in Ten Years
Worth noting: Based on CRFB's "2024 estimates, the tax exemption for nonprofit hospitals will cost the federal government nearly $300 billion in lost revenue over the next decade."
FDA Under Gottlieb Proposed Menthol and Flavored E‑cigarette Ban
In Trump's first term, the FDA under @ScottGottliebMD proposed a ban on menthol cigarettes and most flavored electronic cigarettes
Banning SSRIs Is Unreasonable for Mental Health Care
Absolutely batshit. Can we do better on mental health. Of course. Is banning SSRI even remotely a good idea - not unless you are an utter doctrinaire moron.
INBX to Release INBRX‑106 Phase 2 Data Monday
$INBX reporting INBRX-106 ph2 data on Monday. This is the ox40 cancer drug that reportedly drew interest from Merck and others?
MRNA Nanoparticles Reprogram T Cells In Vivo, Show Promise
Impressive. In vivo reprogramming of killer T cells with mRNA-nanoparticle packaging in non-human primates. Multiple use cases in the clinic vs pathogens and cancer, no less an alternative version vs autoimmune diseases https://t.co/ddhebnxvkE @SciImmunology
Questioning Doctors' Role in the Hemophilia Tragedy
The Hemophilia Holocaust (Are Doctors to Blame?) If you enjoyed this content, then check out my free video podcast at robertlufkinmd.com.
Smart Homes Integrated with Biotech Extend Lifespan
A bigger house is not going to give you significantly longer life. But a much smarter house integrated into the advanced biotechnology research and clinical ecosystem will. Very happy to see our chapter with CY Leung published in Springer Nature...
Billion-Dollar Ideas Lurk in Free PubMed Data
Martin Shkreli came on MFM a while back and told Shaan and I something interesting: PubMed has 40M+ biomedical papers. It's the government database of every medical innovation ever logged. And it's 100% free. He told us if you sit there and read long...
Patents Aren't the Magic Key to Drug Development
The $3 billion number is hokey for a number of reasons, but the point is that there is not some magical sauce that allows for drugs to be developed when financed by patent monopolies, but not by upfront funding.
CDC Alerts New Jersey of Possible Hantavirus Exposure
JUST IN: The CDC has notified New Jersey health officials about 2 residents who may have been exposed to hantavirus
Mabwell IPO Highlights China’s Rising Biologics Powerhouse
Do you remember the company which sold their IL11 nanobody to Google Calico after it realized that after 13 years in the business they need a drug for aging? The company is called Mabwell and they just listed in Hong...
Tech Exists, Consistency Lags in PHI Consent
The tech exists. Consistency doesn’t. Kevin Day from The Sequoia Project on PHI consent in healthcare. 👉 https://t.co/ti26EESrJQ @sequoiaproject #PatientPrivacy #HITSM https://t.co/f6bscBfoXP
Men Deserve Equal Fertility Testing, Not Just Semen Count
The average couple at a fertility clinic gets the woman tested across multiple organ systems and hormonal axes before the man gets a single semen analysis. She gets an HSG, ultrasounds, AMH, FSH, thyroid, and prolactin. He gets a basic...
AI-Driven Bioterrorism Threat Demands Strong CDC‑WHO Collaboration
Why we still need a functional CDC and cooperation with the WHO. The chances of an AI-enhanced bioterrorism event in the world is not zero.
Rethinking Diabetes: Why Our Treatment Fails Millions
Ever wonder how we got in such a screwed up situation in the misguided way that we treat Type 2 diabetes and the resulting suffering of millions? Well, garytaubes spells it out for us all in chilling detail in his brilliant...
Narcan Distribution vs Costly Interventions:
Does anyone have insights on relative impact on drug overdose deaths of the wide distribution of Narcan vs the other (far more expensive) interventions we have put in place?
AI Talent Shuns Pharma, Feeling Reduced to Code Writers
Astute @endpts article on why rising AI talent not drawn to pharma; $ part, but key reason=“Pharma might just see us as people who write code or run models for them, and not really value for research." Mirror image of...
Rapamycin's 50-Year Odyssey: From Easter Island to Medicine
The rapamycin sTORy: 50-year journey from Easter Island to the frontiers of biology and medicine https://t.co/Jn67QrGVi6 https://t.co/dwGPgUVB83
Fewer Visits Demand Trust, Answers, and Action
Less traffic = higher stakes Every visit now has to: ✔ Build trust ✔ Answer questions ✔ Enable action Ahava Leibtag breaks it down 👉 https://t.co/GA9oYQP470 @ahamediagroup #healthcarewebsites #hcmktg
ZYME ADC
Catching up with $ZYME pan-RAS inhibitor payload ADCs from #AACR26. Seems the setting for each one is tumours that are RAS-mutated as well as expressing the target antigen (PTK7, Ly6E or Claudin18.2). https://t.co/hljX5soZQi
FDA Greenlights Fruit-Flavored Vapes, Sparking Controversy
The FDA finally authorized fruit-flavored vapes. It's quite a story. @imaracingmom explains in @Filtermag_org #smoking #vaping https://t.co/11alD0xXCP
Privacy‑Preserving Symptom Check‑Ins Accelerate Outbreak Detection
This is the hard part of travel- and event-linked public health events: People disperse before symptoms appear. A cruise, flight, conference, camp, or large gathering may be over — but the signal emerges days later, scattered across states and countries. We need better...
AI-Generated Hospitalization Summaries Cut Clerk Workload, Boost Physician Well‑being
Agentic AI summaries of hospitalizations were safe and reduced data clerk burden, burnout, and improved sense of well-being for physicians in a prospective study https://t.co/0nXZ0wjugg
U.S. Death Rates Remain Higher Than Peers Despite Equal Tech
"Despite similar access to advanced medical technology, the US has experienced persistently higher death rates than other high income countries" https://t.co/iIe8UJbUCs
Measles Cases Surge: 80% of 2026 Total in 4 Months
#Measles is still doing in the US what measles does super well — spreading. As of 5/7, there have been 1,842 confirmed cases this year, which is 80% of the 2026 total in just over 4 months. https://t.co/fMaSWEJiUL
Nobel Laureate: Decriminalizing Taboo Markets Saves Lives
What do kidney sales, surrogacy and sex work have in common? A Nobel laureate says decriminalizing these taboo markets can save lives https://t.co/qWXRewcWH7 via @felixsalmon https://t.co/zUV2oscgvq
NEJM Publishes Moderna Flu Data After FDA Refusal
A Friday footnote: The New England Journal of Medicine has published the Moderna influenza vaccine data -- the same that led the FDA's CBER division to refuse to review the vaccine under Vinay Prasad. (That decision, called a refuse-to-file or...
Unexplained Infertility Is a Diagnostic Shortcut, Not a Mystery
"Unexplained infertility" is the most overused diagnosis in fertility medicine. It almost never means there is no cause. It means the standard panel did not find a cause. Almost every couple we meet at Ferta who was told they had...
Psilocybin Shows Promise After Decades of Failed Cocaine Treatments
For 50 years the National Institute on Drug Abuse has spent hundreds of millions of dollars to find an effective cocaine addiction medication. After 100+ molecules & many hundreds of studies nothing has been FDA approved. It's the Holy Grail...
Metformin's Primary Action Is Gut, Not Liver
Metformin, one of the most commonly prescribed drugs, was thought to work via the liver. Check that. It's primarily through the gut. @NatMetabolism https://t.co/i2CpZip61B https://t.co/bhsI7p7SYx
GLP‑1 Breakthrough Costs $500/Month, Limiting Access
After catching my breath (unusual for GLP-1 story to discuss their costs approvingly), I suspect both that @continetti (not unusually) is likely directionally right (& I share enthusiasm for free market) - but - at $500/mo for transformative drug -...
Compassion, Not Tech, Defines Top Cardiology Care
My dear 92yo mother-in-law did not survive her heart attack. The CCU team showed our family what cardiology at its best looks like, and it wasn't the technology. My @JACCJournals Editor's Page on the experience: https://t.co/RzhvSMOm8R https://t.co/nFTQmR06sK
Heart, Kidney, Metabolic Issues Raise Cancer Risk 30%
Heart, Kidney, Metabolic Disease Linked to 30% Higher Cancer Risk As a medical school professor, I teach cardiovascular and cancer medicine as separate silos. A new study of 1.4 million adults says we have to stop. Circulation: Population Health and Outcomes, April...
Episode 400: Daphne Zohar on Seaport’s IPO Success
On this week’s Readout LOUD podcast, @daphnezohar was our very special guest. We chatted about Seaport and its successful IPO. Also, this week is Episode No. 400! https://t.co/5o02LIjjD6
Doctors Must Google Themselves to Avoid Misidentification
Tag a physician who has never Googled their own name. They need to. Dr. Stephanie Waggel did, and the top result wasn’t her. It was a large corporate clinic she has no affiliation with. Save this before the next time...
Voluntary Certification Becomes Unavoidable Gatekeeper in Medicine
A classic episode, republished in memory of Dr. Manny Konstantakos, an orthopedic surgeon and longtime advocate for physician choice in board certification, who passed away suddenly in 2023. Maintenance of Certification is voluntary. Hospitals will not credential you without it. Insurers...
AI‑enhanced Dog Breath Test Detects Cancers with 90%+ Accuracy
New MCED / cancer screening test: Dogs smell human breathing + Bayesian AI detects multiple cancers with 90.8% sensitivity & 91.3% specificity (AUC 0.962), even in early stages. Phase II India study (1,502 people, 7 cancer types)- strong potential for affordable...
Google Launches AI Health Coach to Interpret Wearable Data
Wearables can measure every vital sign or health parameter that matters in adjusting your lifestyle. But what the user does with the data remains the biggest challenge. Now Google wants to solve that too. After OpenAI and Anthropic came up with...
Dual‑LAO Accelerates Robust Binding Free Energy Calculations
New paper published @CommsChem with the @qubit_pharma team led by @Narjes_Ansari: "Dual-LAO for calculating fast and robust relative binding free energies of simple and complex transformations" (#OpenAccess) #compchem #drugdesign @FefeAviat J. Hénin L. Lagardère https://t.co/ktdX8AWMBo
Autonomous Robot Achieves Zero‑Error Blood Draws
Zero-Error Blood Draws: Fully #Autonomous #Robot Handles Vein Detection to Injection by @Berci #MedTech #Healthcare #HealthTech #Tech #Technology https://t.co/2ZzoRdwtqP
Boomers 80, $79T Wealth Fuels Healthcare Boom
A decade ago. We were lectured and lectured and lectured again - over and over again from Wall St. analysts. "The USA has an aging population. Health care is the undeniable sector of the future." Today, the oldest baby boomer...
ART Reverses HIV‑Induced Aging, Cutting Years Off Biological Clock
Great news for HIV positive patients. A study presented at ESCMID Global 2026 found that untreated HIV can accelerate biological aging by up to a decade, but antiretroviral therapy can reverse this effect by nearly four years within about 18...
Private Healthcare Fuels Billionaire Wealth, Not Universal Care
No universal healthcare. 1,000 billionaires. And at least 49 of them got rich specifically from private healthcare.