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[Comment] Managing Complex Antiretroviral Regimens

Switching antiretroviral therapy (ART) in people with HIV who have achieved sustained virological suppression is now a routine part of modern care. Advances in drug formulation, tolerability, and the rise of single‑tablet regimens have expanded treatment objectives beyond viral control. Clinicians increasingly prioritize long‑term safety, regimen durability, adherence optimization, and overall quality of life when selecting or modifying therapy. The shift reflects a broader move toward patient‑centered HIV management.