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Optibrium has released a new PyMOL plugin that adds a graphical user interface to its QuanSA ligand‑based affinity prediction tool. QuanSA uses physically‑motivated machine learning to deliver free‑energy perturbation‑level accuracy without needing a protein structure, dramatically lowering computational cost. The GUI visualizes key surface‑field interactions, letting chemists obtain quantitative affinity scores within minutes and streamline lead‑optimization cycles. The plugin is free for existing BioPharmics license holders, expanding access to the method across the chemistry community.
Portman Holdings is expanding its Savona Mill adaptive‑reuse development in Charlotte with a Phase II add‑on of 330 multifamily units. The historic 108‑year‑old mill, which already delivered 319 apartments in Phase I, will also feature eight townhome pads and extensive amenities. Construction...
MXR Hospitality has named former McNeill Hotel Company president Travis Murray as its first executive vice president of operations. Murray will oversee the hotel portfolio’s day‑to‑day management, brand and owner relationships, and drive growth of MXR’s third‑party property‑management business. He...
Crude oil futures experienced a dramatic swing from $84.37 to $101.67 after President Trump’s Truth Social remarks, highlighting the market’s sensitivity to geopolitical headlines. The contract now sits near $92.68, just below the 50% midpoint of $93.02, keeping sellers in...
Trump’s war in Iran is putting extreme pressure on global oil supplies, driving up crude prices that now may stay higher for longer. My @morningjoe Chart
LondonMetric Property and Schroders Real Estate Investment Trust are reportedly weighing an all‑share bid to acquire Picton Property Services. The proposal would involve exchanging shares rather than cash, preserving liquidity for Picton’s shareholders. Picton has not received a definitive offer...
$8T+ Oil & Gas market. Goldman sees $115 crude. When prices rise, cash flow explodes across the energy stack. Here’s who wins 👇 Oil demand >104M bpd. Gas >4.2T m³. Supply stays tight while LNG demand grows. Goldman’s near-term price targets show...
Rising gas prices caused by the war are already hurting Americans’ bottom line — in both expensive and affordable states. On average, Americans are paying almost $1 more per gallon than they were last month. My @morningjoe e Chart
Netflix’s animated hit “KPop Demon Hunters” became the platform’s most‑watched film, earned an Oscar and launched a massive merchandising line. After the breakout, directors Maggie Kang and Chris Appelhans secured an exclusive five‑year agreement worth roughly $10 million per year, plus...
The Securities and Exchange Board of India (SEBI) has overhauled its conflict‑of‑interest code, bringing the chairman and whole‑time members under insider‑trading norms and expanding the definition of "family" to include spouses and dependents. While the changes tighten internal governance, the...
The author updates a 2024 list of screenwriting contests, fellowships, and labs, now presented in a detailed Google Sheet. They highlight the extremely low odds—about 1 in 100,000—of winning or placing in these competitions. Proactive outreach after a placement is...
South Africa’s gold production has stalled at roughly 90 tons a year, a sharp decline from its 1970 peak of 1,000 tons, despite a 60% surge in gold prices over the past year. Dwindling reserves, labor unrest and the extreme...
The Academy of International Mobile Healthcare Integration announced the winners of its 2026 Excellence in EMS Integration Awards. Recipients include Sonoma County Fire District EMS, Rep. Mike Carey, Medic Keep the Beat Foundation, Prisma Health Ambulance Service, Justin Duncan, and...
KeyCare, the nation’s only Epic‑based virtual care group, has launched NVIDIA’s Nemotron large language model in production to power its AI‑driven patient intake agent. The agent, embedded in KeyCare’s virtual waiting room, captures and summarizes clinically relevant Epic data before...
Alnylam Pharmaceuticals announced a strategic partnership with Viz.ai to develop an AI‑enabled care pathway for earlier detection of transthyretin amyloid cardiomyopathy (ATTR‑CM), launching the AWARE study in five health systems. The company also pledged support for the American Heart Association’s...
Lockheed Martin successfully completed the first live‑fire and vertical‑launch test of a Hellfire missile from its new GRIZZLY containerized launcher. The system fits inside a standard 10‑foot Tricon container and was developed in just six months using existing M299 launcher...
Industrial Encoder Corporation launched the DWS1215 draw‑wire encoder system, offering precise linear position feedback up to 15 m. The device provides both incremental and absolute outputs with ±0.01 % linearity and high‑flex stainless steel wire. Targeted at printing, material handling, elevators, gantries,...
SFL Missions Inc. won a competitive contract to build eight 150‑kg Node spacecraft for NASA’s HelioSwarm mission, a MIDEX‑class solar‑wind science observatory. The Nodes will be launched aboard a larger Hub spacecraft and deployed into a lunar‑resonant orbit to capture...
The American Institute of Aeronautics and Astronautics (AIAA) marked the March 9, 2026 announcement of the eVTOL Integration Pilot Program (eIPP) awardees, highlighting a milestone in advanced air mobility (AAM) integration. Over the past decade, AAM has evolved from early concepts like...
NASA announced it will cancel the Lunar Gateway orbital station and redirect its resources to build a $20 billion lunar surface base over the next seven years. The decision was made by new NASA chief Jared Isaacman, who said the agency...
A Jamestown Foundation study identified Senator Yuen Pau Woo’s newly formed advocacy group as the 576th Canadian organization linked to the Chinese Communist Party’s United Front Work Department. Woo publicly attacked the study, labeling it disinformation and accusing Canadian officials of enabling...
Karyopharm reported mixed results from its Phase 3 SENTRY trial of selinexor in myelofibrosis, achieving a statistically significant reduction in spleen volume but raising safety concerns. The data fell short of expectations for overall survival benefit. Meanwhile, Rezolute announced it will...
Tiltify reported that creators donated more than $100 million in 2025, roughly double its 2024 total, cementing creator‑led philanthropy as a major growth engine. The platform’s tools—especially creator‑designed incentives, auctions and matching challenges—accounted for 40% of the funds raised, up from...
India, the world’s second‑largest buyer of liquefied petroleum gas, is seeing supply constraints from the ongoing Middle East war. In Delhi, black‑market cylinder prices have jumped from roughly $20 to $53, about double a typical low‑income household’s monthly earnings. Consequently,...
I’m excited a new noninvasive way to evaluate endothelial function. Stay tuned for a deeper dive as I test it on myself. https://www.vendys2.com/drlufkin VENDYS_2
Utilities trying to stabilize today, spike in rates finally ready to cool off? $XLU https://t.co/t5R7ZEkbQT
Apple TV+ confirmed that the alternate‑history space‑race drama "For All Mankind" will conclude with a sixth season, following the May 29 return of Season 5 told from a Soviet perspective. The renewal secures a final narrative arc, likely slated for 2026,...
I’ve been waiting literally decades for NASA to articulate a plan for a Moon base. Now Carlos Garcia-Galan is doing a masterful job of precisely this. Dozens of landings. Drones. RTGs. Rovers. Habitats. Excavators. This is incredible stuff.
HOUSTON — Interior Secretary Doug Burgum shared a stage Monday with the CEO of a French oil giant to take aim at offshore wind — a rare alignment between a government and a private company. https://t.co/yTj5IR5OwH via @axios
On October 24, 2024, the Bahamas‑flagged tanker Platanos struck the Martinez Refining Company Wharf in California while undocking, causing a hole above the waterline and $500,229 in damage. The NTSB investigation found the ship’s pilot mistakenly transposed the names and...
Neither were the Netherlands 🇳🇱 always a cycling country. A 1970s grassroots movement and responsible politicians made it one.
Exclusive: US SEC's ex-enforcement chief clashed with bosses over Trump cases before leaving, sources say https://t.co/Z4sEYxud0H
ClearPoint Strategy’s 2026 Strategic Planning Report examined 20,582 plans across seven industries, analyzing 31.2 million data rows. Completion rates vary dramatically, with Energy & Utilities leading at 25.81% and nonprofits lagging at 5.29%. Plan size, team composition, and ownership gaps differ...
Guy who clearly understands how oil markets work: "see, we never needed the Strait of Hormuz 😏"
Industrial supply chains are increasingly exposed to AI‑driven cyber threats that bypass traditional perimeter defenses. Vendors, OT devices, and cloud services now intersect, creating a unified attack surface where a single compromised credential can cascade across production, logistics, and revenue...
President Donald Trump used Truth Social to declare an end to the Iran war, prompting stock futures to rebound and oil prices to tumble before Iran’s foreign ministry denied any cease‑fire. Simultaneously, the administration sent ICE agents to thirteen airports,...
NASA announced that a lunar outpost is now a formal element of its upcoming roadmap, moving the Artemis program toward a twice‑annual launch cadence. The agency also unveiled plans to field a nuclear‑propelled spacecraft for a Mars mission by the...
When it comes to housing, Florida doesn't do "average" It overheats more during booms—and corrects more during downturns Florida is the epicenter of the boom-bust phenomenon https://t.co/q5q3SyDu44
South Florida Judge Ernest Kollra ruled that three Miami‑Dade police officers involved in the 2019 fatal shooting of UPS driver Frank Ordonez cannot be prosecuted, invoking Florida’s “stand your ground” law. The decision follows a similar ruling in September that...
According to @Polymarket, there is a 55% chance US forces enter Iran by the end of April. Forget Trump’s talk of the art of the deal. He takes his orders from Jerusalem. https://t.co/GgrtwQc8kz
A new FMCSA‑based study of 314,078 interstate for‑hire carriers links insurance underwriting type to safety outcomes. Non‑underwritten carriers consistently post higher composite risk scores and dirty‑inspection rates than peers in underwritten programs, with gaps widening for mid‑size fleets. Risk Retention...
Ars Technica’s first installment examines whether orbital data centers can be economically viable. It notes that deploying a million satellites would cost over $1 trillion, dwarfing the roughly $10 billion budgets of SpaceX’s Starlink and Starship projects. Engineers argue that owning both...
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The article introduces “ghost citations,” where large language models (LLMs) cite a brand’s content but omit the brand name from recommendations. Seer’s analysis of 541,213 LLM responses shows citation rates jump from 10.6% to 53.1% when a brand is mentioned,...
Third‑party logistics providers (3PLs) face mounting pressure as shippers seek greater resilience, reliability and real‑time data amid rising costs, labor shortages and geopolitical volatility. Industry leaders like Ryder emphasize deep customer understanding, rapid startup execution and continuous KPI‑driven improvement to...
Georgia Ports Authority is set to launch a $134 million inland port in Gainesville this May, designed to handle up to 200,000 containers annually once fully built. The site will be anchored by a 540,000‑square‑foot warehouse from Alliance Industrial and a...
Interesting. FCC has banned the import of all new consumer routers manufactured outside of the US. https://t.co/AtctxEoKFs
Check out this edition of the Art of Supply newsletter for a deep dive into the supply and cost dynamics of the coffee supply chain. ☕ https://t.co/JyZWYKIpxp
Mesa City Council unanimously approved a new landing‑fee structure for Falcon Field Airport, effective May 1. The fees are designed to close a projected $2.0 million budget shortfall and are expected to generate about $2.9 million annually. Based aircraft receive the first ten...
Generative Design Meets Metal #3D Printing: One Click Metal’s #Drone Frame Takes Flight via @WevolverApp #3Dprinted #Technology #Innovation #EmergingTech #TechForGood https://t.co/94TJLJ6Plc
Elevate Renewables developing 600MWh New Jersey BESS through state’s energy storage programme #energysky -- via Energy Storage News: https://t.co/VU9uoJjmEW
