What's happening: Ease Health lands $41M Series A to boost AI‑driven health‑tech platform
Ease Health, a New York‑based AI‑native CRM, EHR, and RCM platform, closed a $41 million Series A round led by Andreessen Horowitz. The funding will expand product and engineering teams and accelerate AI automation across its suite, underscoring investor confidence in integrated health‑tech solutions.
Also developing:

Lambda, the Nvidia‑backed cloud‑computing firm, announced a multi‑billion‑dollar agreement with Microsoft to deploy tens of thousands of Nvidia GPUs, including the new GB300 NVL72 systems, deepening an eight‑year partnership. While the exact dollar amount was not disclosed, the deal adds significant AI super‑computing capacity to Microsoft’s Azure platform, which opened its first GB300 cluster in October. The announcement follows a wave of large AI‑compute contracts, such as Microsoft’s $9.7 billion deal with IREN and OpenAI’s $38 billion pact with Amazon, highlighting soaring demand for AI infrastructure. Lambda, which has raised $1.7 billion in venture funding, is positioning itself as a key supplier in this expanding market.
I just got an Adobe Sign email, deal sign for @saastrfund! Hooray!! But the copy in the email I wrote in 2005. Yes, 2005. Before we launched. We used to tolerate this in SaaS because it was so much...
I wake up, have some coffee, answer a few emails And then ... fire up Replit and other AI Agents. And we just pick up right where we were yesterday. No complaints. No arguments. No forgetting. No sick days. No b.s. No drama. No pretending. No quitting. The reality is, this...

This week’s SaaS roundup highlights a wave of large AI‑focused funding rounds, with companies like Sublime Security, Harvey, and ConductorOne each raising $150M‑$79M to deepen product AI capabilities and expand globally. Major M&A activity includes NEC’s $2.9B purchase of CSG...
https://t.co/8kfP3o3TrD What happens when one of the most human-centric roles in business—Revenue Operations—meets the most transformative technology of our time? Join me, and Meredith Schmidt, longtime Salesforce executive and trailblazer in modern RevOps, for a provocative conversation on how Agentic AI is...
You likely have people on your team that have been consistently *right* most of the time. They tend to push for a particular decision/path and turn out to be right over the fullness of time. Let's call them "Ingrid The...

Younger workers, particularly Gen Z, are turning to AI note‑taking tools instead of attending meetings, with 19% of all workers and 26% of hybrid employees using them frequently, compared with 13% of in‑person staff. The Software Finder study links frequent...

Fitbit’s entry‑level Inspire 3 has been slashed to $69.95 on Amazon, a $30 drop from its regular $99.95 price, and now bundles six months of Fitbit Premium at no extra cost. The tracker offers continuous heart‑rate monitoring, sleep analysis, Active Zone Minutes...

Frameworks, metrics, strategy—yes, they matter. But the hardest parts of work are often the soft, messy, human parts we rarely discuss openly. The self-doubt, anxiety, the interpersonal dynamics that get in the way of actually getting things done. I'm excited to...

Synthesia just raised $200M at a $4B valuation after rejecting Adobe’s $3B offer. Here’s how they're building for the long game👇

OpenAI has launched Aardvark, an autonomous AI agent built on ChatGPT that scans code, runs tests and proposes patches to fix software vulnerabilities at scale. In private‑beta testing the tool achieved a 92% success rate on benchmark “golden” repositories, and...
Synthesia just raised $200M at a $4B valuation after rejecting Adobe's $3B offer. Here's how they're building for the long game Some context: Back in 2017, Victor Riparbelli left Copenhagen for London. AI wasn't a hot topic. VR was. He didn't know what to...
The startup world has been selling founders a lie. The lie: be grateful for any check, valuation is everything, giving up control is normal. This mindset benefits investors, not you. But some founders are waking up and choosing a different path. A smarter path. Like...

Security researchers at Expel have uncovered a new ransomware distribution campaign by the Rhysida gang that uses spoofed Microsoft Teams ads on Bing to lure victims to counterfeit download pages. The pages deploy two loader malware families, OysterLoader and Latrodectus,...
Every B2B founder I talk to wants to start posting on Linkedin. But 95% of them have no idea where to start. Here's a list of 9 content ideas that helped me go viral and generate 50M views on Linkedin...

I was reading a Gallup analysis on workplace tech adoption, and it sparked a bigger reflection. When employees have influence over the tools they use, their job satisfaction climbs sharply. In fact, workers who say they have a lot of...

The article outlines five essential strategies for creating a durable data foundation that powers AI, beginning with unifying customer identities across systems to eliminate fragmented profiles. It stresses the need for clean, up‑to‑date data to prevent AI failures, recommends a...
Melanie Perkins (co-founder and CEO of Canva) on "Column B" thinking: "There are two ways of planning. Imagine you you're building a castle on the hill. One way is imagining what would be the most magical, wonderful, mythical, castle you...

A few months ago, @MrWillNelson had a simple idea: What if founders could grow their audience on social media just by talking? That idea became TalkStories, a tool that calls you daily, captures your insights, and turns them into posts. I’ve used the...

Jason Lemkin reports that SaaStr’s AI‑driven SDR booked a six‑figure sponsor meeting at 6:02 PM on a Saturday, a task virtually no human rep would perform. He argues AI’s value lies in handling the low‑energy, time‑sensitive GTM work that humans avoid,...

Agentic AI, autonomous systems that can reason, adapt and act without constant prompting, is poised to become a major disruptor in cybersecurity, with forecasts that one‑third of enterprise applications will embed such agents by 2028. The technology promises to alleviate...
Startups are 1 step back, 2 steps forward, 1 step back, 2 steps forward, etc. From the outside, HubSpot might seem like a smooth up-and-to-the-right story. It belies what actually goes on inside. The best way I’d describe HubSpot is two...

Google Labs, in partnership with DeepMind, has launched Pomelli, an experimental AI marketing platform aimed at small and medium‑size businesses. The tool builds a brand profile from a company’s website, then suggests custom campaign ideas and generates on‑brand assets that...

The post lists the ten most common errors founders make when hiring a VP of Sales, emphasizing that a successful hire must deeply understand the product, be willing to sell and close deals themselves, and bring a ready pipeline of...
Terence Kawaja and the team at LUMA Partners share the latest data on #martech and #adtech M&A activity from Q3. Overall, the market for martech acquisitions has remained healthy. Although, given how many pre-2020 martech companies are looking for an exit,...

Medha Agarwal of Defy VC warned that traditional seat‑based SaaS pricing is being eclipsed by transactional models as AI‑first products can replace or augment labor, allowing companies to sell into larger labor budgets. Transactional pricing—either input‑ or output‑based—captures more value...

If you want to build a predictable growth engine in your SaaS company, there's one skill that changes everything: learning how to make paid ads profitable. When you understand your unit economics and can generate customers at a cost that...
How to Build a B2B Ad Strategy That Actually Scales If you want predictable growth in your SaaS, there's one skill that changes everything: mastering paid ads. When you know your unit economics and can acquire customers at a cost that...

In this episode, Faire’s data team members Tim Trueman and Alexa Cerf demonstrate how they use AI‑powered tools—such as Cursor, ChatGPT Deep Research, and Model Context Protocols—to quickly diagnose conversion drops, evaluate experiment outcomes, and turn raw data into polished,...
100% agree. For me, $0 - $20K MRR was game-changing! Anything after $20K MRR is making my stock portfolio grow faster, but I can't feel any difference day-to-day. With a bit of planning and picking the right country to live in, you...
This is obviously an extreme example of the productivity gains with AI agents. We can debate the numbers on this. Maybe it’s 10X or 100X vs 1000X, but the direction is correct. What’s going to happen is we’ll just completely...

Nasdaq reached a new all‑time high and Nvidia topped a $5 trillion market cap, underscoring the AI‑driven rally in public markets. Yet the week’s two B2B SaaS exits—Navan’s IPO at a $4.7 billion valuation (7.7× 2024 revenue) after a 20% opening‑day drop,...
bringing this back. very hard to hit $100m ARR with avg price point of $2k/yr
How AI Is Protecting Logistics Workers During The Holiday Rush via @forbes @Samsara https://t.co/XZ1A8TBTXx
year end financial audits founders, what are you paying? is $78k too much?

This founder is basically giving it away to move onto a new startup. Live on @acquiredotcom: VC backed cold email SaaS with AI-powered outreach and smart inbox management. > $495K TTM revenue > $155K TTM profit > 100% YoY growth Full listing: https://t.co/iY13bIBtfn https://t.co/ID2m72SOGo

Congrats to Mecha Health on their $4.1M seed! They’re building next-gen foundation models for healthcare, starting with medical imaging. Mecha Health's systems help radiologists work faster and with greater accuracy, without feeling like they’re doing more work. https://t.co/bSUYgKkf5h

Is your rev rec messing up your retention? 📉 Learn how to clean your retention metrics with a pro forma MRR schedule — and why invoice data is your real source of truth. Watch here 🎥 https://t.co/bII7ixXC6d #SaaSMetrics https://t.co/5d7ZmKnORA
Moss (@usemoss) is the real-time semantic search for conversational AI. By bringing retrieval latency under 10 ms, Moss makes AI conversations feel natural, as fluid and instant as talking to a human. https://t.co/UtnwaJZVNY Congrats on the launch, @srimalireddi & @ImHarshaNalluru!
Want leads? Want to meet 2,500+ of The Best in B2B + AI? It's the LAST CHANCE to sponsor SaaStr AI London Dec 1-2! Join the best of the best, from @Replit to @DuploCloud, from @cleverbridge to @happyfoxchat, from @AvaArtisan to @remote!! ...
Unsiloed AI (@UnsiloedHQ) builds APIs to parse multimodal unstructured data like PDFs, PPTs, and images and convert it into LLM-ready formats like markdown and JSON. https://t.co/f4RJStJIcE Congrats on the launch, @__Aman_Mishra & Adnan! https://t.co/wgEvXw8wj7
New!! AI App of the Week: Assistant UI – The React Library That’s Eating the AI Chat Interface Market https://t.co/Yg3QisTxnX
New!! “Nasdaq Reaches Another ATH. Nvidia Tops $5T. But Navan’s IPO and JAMF’s $2B Exit Show B2B Still Isn’t Easy.” https://t.co/T5c5VRn0Sp https://t.co/T5c5VRn0Sp

Over 30 community meetups scheduled this month all over the world. From Amsterdam to Bangkok, to Dubai to Taipei. All grassroots and self-organized by readers. Unreal. https://t.co/LCHesYCxbN
So I've been vibe coding for about 4 months and shipped 10 apps and now I'm doing something I didn't want to do. I'm starting to build our own vibe'd marketing automations (on top of Resend). If there's one thing...
"I don't want to look at the bricks around me and ask how high I can stack them. I want to design the most magical, wonderful, mythical castle on a hill and then figure out how to build it." Melanie...
Sciloop (@SciloopAI) automates the entire scientific research loop from hypothesis generation to experiment design, execution, analysis, iteration— and drafts real research papers. https://t.co/r1FbEEsymk Congrats on the launch, @bilalasmat04 & @OsmanSiddiquer! https://t.co/Joyoks9w6v
Update: 🤖25% of our pipeline in past 60 days was from our AI BDR Not 100%. But up from 0% 90 days ago.
If your deals aren’t closing… If your demo calendar is empty… If your outbound DMs and Emails are hearing crickets… Then it’s time to fix your broken Go-To-Market Strategy. Now there’s tons of advice out there on that one new growth hack.
AnswerThis (@answerthisio) is the AI assistant that helps researchers find, analyze, and write research papers. Over 250k researchers visit https://t.co/n4pWiYjHyS monthly to go from research question to publication on one workspace. https://t.co/CSkZcXirW5