Fewer Cagemates Increase Female Mice Mortality
Association between cagemate number and risk of death in mice: a time-varying covariate analysis using Cox frailty models "...Female mice exhibited a pronounced increase in mortality rate as cage density declined..." https://t.co/pGtDArEzI0 https://t.co/5gizWZ0QYo
Micro-Cages Enable Precise Manipulation of Cell Clusters
These micro-cages are designed to hold and manipulate tiny cell clusters in miniaturized lab-on-a-chip devices. https://spectrum.ieee.org/lab-on-a-chip-grippers?share_id=9241061
First Human Age‑Reversal Trial Targets Whole‑Body Reset
The first human age-reversal trial is officially happening. But before the FDA cleared it, Harvard professor David Sinclair had to pull off a mice experiment most scientists thought was impossible: "These mice had their optic nerve regenerated. We were able to...
Chinese Ceramic Endures 3272°F, Transforming Space Heat Shields
#WhatsNext? Scientists in China created ceramics that survive 3272°F, 1800°C! Could revolutionize how heat shields are used by spacecraft. (Engineering Post) #NewMaterials https://t.co/Wr6wLsUfxe
FoxO3a Boost in Dentate Gyrus Eases Stress‑induced Depression
Overexpression of FoxO3a in the dentate gyrus alleviates CUS-induced anxiety- and depression-like behaviors and cognitive impairment https://t.co/p2t18NRkew
Cut dAGEs, Boost Longevity with Smart Nutrition
Dietary Advanced Glycation End Products (dAGEs): Pathogenesis and nutritional strategies for health longevity-A critical view https://t.co/RrTxgGg4UF https://t.co/ujoKGLKIRz
EpiAge‑R Integrates Epigenetic Clocks, Resilience, and Multi‑omics Ageing
Epigenetic Clocks, Resilience, and Multi-Omics Ageing: A Review and the EpiAge-R Conceptual Framework The hierarchical architecture of the EpiAge-R framework... https://t.co/YpwDdLI7wo https://t.co/Uid3kNzDHr
Ayahuasca Shows Mixed Impacts on Cognition and Social Insight
Effects of ayahuasca on neuropsychological performance and social cognition: A systematic review - Caio César de Paula, Anna Beatriz Vicentini, Lorena Terene Lopes Guerra, José Carlos Bouso, Jaime E. C. Hallak, Rafael G. dos Santos, 2026 https://t.co/oXP57hmeR1
Mainstream Finally Aligns with Evidence‑based Longevity Strategies
About time. Atherosclerosis is a lifelong process, and it’s genuinely rewarding to see mainstream recommendations finally begin to catch up with what we in evidence-based longevity have been doing for years. 👨🏻⚕️⚕️
Sea Level Rise Threatens Far Greater Fatalities Than Expected
A deadly climate change effect is even worse than feared, study finds” by Doyle Rice for @usatoday: https://www.usatoday.com/story/news/nation/2026/03/08/sea-level-rise-study/89002601007/
Adenine Methylation Forms New Linear Brain Aging Clock
A completely novel axis of epigenetic aging. N6-methyldeoxyadenosine (N6medA), i.e. NOT the usual 5 methyl cytosine, increases linearly with age in human prefrontal cortex (r=0.95). Genome-wide profiling reveals age-associated ADENINE methylation changes reminiscent of classic CpG based epigenetic clocks. Abdur...
Math Rules Behind Firefly Sync Guide Swarm Robotics
Engineers have identified mathematical rules behind firefly synchrony in South Carolina swamps, offering insights that could inform swarm robotics and deepen understanding of biological synchronization, such as neuronal and circadian rhythms. biology
Flushed Plastic Wipes Flood Rivers with Microplastics
Plastic-based wet wipes, often flushed due to unclear labeling, are a significant source of microplastics in rivers, shedding microscopic fibers that may threaten aquatic ecosystems. microplastics
DNA Tools Outpace Pedigrees in Detecting Wildlife Inbreeding
DNA-based tools provide more accurate and responsive detection of inbreeding in wildlife populations than traditional pedigree methods, offering critical insights for effective conservation management and genetic rescue efforts. conservation
Vaccination Boosts Survival in Multiple Myeloma Patients
Rates of Influenza and Pneumococcal Vaccination and Correlation with Survival in Multiple Myeloma Patients [Dec 6, 2022] @mtmdphd et al. @AjaiChari CLML https://t.co/kUQeRmdKWV #NCT02761187 #mmsm #IDonc #ClinicalTrials #caxtx https://t.co/L7r9caCcGN
MRD‑Negative Patients May Stop Myeloma Maintenance Therapy
Discontinuation of maintenance therapy in multiple myeloma guided by multimodal measurable residual disease negativity (MRD2STOP) - @bdermanmd et al. @ajjakubowiak #ASCO24 Abstract 106 https://t.co/FBTY7SnCxK #NCT04108624 #mmsm #mmMRD
Clinicians Show Mixed Adoption of MRD in Myeloma
Clinician attitudes and practices toward measurable residual disease in multiple myeloma [Jun 7, 2020] @bdermanmd @jagoda_jasielec @ajjakubowiak Brit J Haematol https://t.co/8zhxYfYwZQ #mmsm #mmMRD https://t.co/QTlR2gv5Q0
Coffee and Tea Linked to Reduced Neurodegenerative Disease Risk
Consumption of coffee and tea and the risk of developing neurodegenerative diseases: a cohort study in the UK biobank https://t.co/bv0q79xKni
Drones Aim to Detect and Extinguish Wildfires Early
What if we could use technology to identify wildfires, then extinguiwh them before they spread? That’s what Crossfire, a research team, is trying to accomplish with drones. There’s a multi-million dollar contest awarding the best wildfire-dousing tech. #wildfire #drones #tech #fire
Testing Ubiquitin Promoter for Stable Petunia Transformation
Alright, Alice 24-0001 petunia bits co-culturing with Agribacterium strain Gv3101 carrying a PcUBI4::RUBY::THSP construct. Testing out this ubiquitin promoter for stable transformation to avoid silencing. These will bake at 30°C until Monday and then transfered to selection. 🤞 https://t.co/SO1EKELMgU
NAD⁺ Controls Aging Hallmarks, Offering Therapeutic Paths
NAD⁺ as a central hub regulating the hallmarks of aging: Mechanisms and therapeutic implications https://t.co/Mw45GF0QhL https://t.co/pvAGRxXQZv
Shiyan and CZ-2D Upper Stages Cataloged; Others Untracked
Shiyan 30-03, 30-04 and the CZ-2D upper stage cataloged in 587 x 593 km x 35.0 deg orbits following their launch on Mar 12. No orbit data yet for SatNet-LEO12 or Tenkoh-2.
Stevia Boosts Muscle Metabolism and Prevents Loss
If avoiding sugar, consider stevia. A stevia plant extract (from Pharmingen, Korea) improved muscle metabolism, mitochondrial function, and attenuated muscle loss in obese mice while activating SIRT1. Non-ultraprocessed stevia resembles matcha powder 🍵 https://t.co/tWvBmZzk2g
Morning Sun & Exercise Boost Cortisol, Reduce
Resilience is physiological & actionable: Spiking your morning cortisol increase (which is what wakes you up & is healthy) with bright sunlight & exercise, shortens the duration and the amplitude of the cortisol response to afternoon and night time stressors,...
Geroscience Hypothesis Now as Outdated as Flat Earth
The once bold idea that treating aging will treat chronic diseases (which some refer to as the Geroscience Hypothesis) is about as innovative today as the round Earth hypothesis
Syringic Acid Shields Rodents From Neurotoxicity and Inflammation
Syringic acid is a naturally occurring molecule in grapes, olives, pumpkins & herbs with antiinflammatory, anti-microbial & anticancer properties. New study finds it prevents rodent neurotoxicity & inflammation. Not yet sold widely but will be I expect https://t.co/3XtSesFb9I https://t.co/C3RqjvK6NY
Epigenetic Therapy Marks New Era in Glaucoma Treatment
Great to see ophthlamologists adopting epigenetic modifications and resets to treat eye diseases like glaucoma. A paradigm shift in medicine https://t.co/g2gr3WVpkf https://t.co/6gbBVHJuXI
Testing Parsley Promoter RUBY in Stable Petunia Transformation
Okee, two more cultivars to sterilize and transform and I'm done for the day. Let's rile up the agro and get this done. Also among the stuff I need to test for work, I'm going to see if this parsley...
Sauna Use Cuts Cardiac Death 22% and Mortality 40%
The wellness industry loves the word "detox." Doctors prefer the word "data." In this recent episode, we look at why sauna use is linked to a 22% drop in cardiac death and a 40% reduction in all-cause mortality. Is the heat shock...
New Team Targets Longevity Gap Amid Funding Shortfall
Longevity research is being starved of funds just when the US needs to be more competitive. Have assembled a team working on it. Launch date: April 2026 https://t.co/DOgprwaSzv
Bioelectric Fields Redefine Life, Cognition, and Intelligence
Mike Levin discusses his research into bioelectric fields, cognitive glue, cancer treatment, mind blindness, diverse intelligence, multiscale cognition and problem solving. Brilliant work challenging our conceptions of life, cognition and intelligence. https://t.co/rQyS9dU5gJ
Aging Linked to Naive CD8 T‑cell Shortage
Shortage of circulating naive CD8 T cells provides new insights on immunodeficiency in aging https://t.co/NSDiR30N6W
Future Universe: Darkness Fades, New Light Awaits
How dark will the Universe become? #AskEthan Sure, dark energy will empty out the Universe and galaxies will run out of fuel to form new stars. But that doesn't mean our sky will only get darker. Look forward to the brightness ahead. https://t.co/huqNduzpjh
Black Rain in Tehran Signals Dangerous Soot Pollution
Black carbon is the 2nd-leading cause of global warming after CO2, with 1 million x the warming per unit mass as CO2, but with a lifetime of only a few weeks in the air versus decades for CO2 Oil fires produce...
Parsley Uniquitin Promoter Matches 35S at 72
Great signal at the 72hr mark which is peak RUBY accumulation. Parsley uniquitin promoter as reliable as 35s for my projects. Glory be. Here's the expired patent: https://t.co/njN84BkHho https://t.co/kDfx1RoenJ
Your Baby’s Cells Live Inside You for Decades
They say motherhood changes you forever. Anyone who's a mother knows this is 100% true. But most people don't realize that it happens at a cellular level. ...
Cancer Vaccines Show Promise for Hard-to-Treat Tumors
Cancer vaccines are showing marked efficacy vs refractory cancers and are going to be part of the future Rx armamentarium. Beyond that, ultimately, for prevention in high-risk individuals. A new stellar review @NatureMedicine https://t.co/PhtdZDtSBl https://t.co/okmwCD8AyB
AI Helps Predict Upcoming El Niño, Climate Scientists Say
Also: How climate scientists are using AI and El Niño is on the horizon. https://t.co/Hch1WACEJx
Biology's Slow Validation: AI May Accelerate Breakthroughs
In my experience, ideas that take seconds to conceive take years to confirm in the lab and 1–2 years to get published in a top journal. This is biology’s Achilles heel Let’s see if AI can fix that https://t.co/3On4DrTcU6
Amyloid Antibody Therapy Triggers 100 Microhemorrhages in APOE4 Patient
100 brain microhemorrhages in a patient with cerebral amyloid angiopathy and 2 copies of APOE4 after amyloid antibody therapy https://t.co/ASpVuijFNW https://t.co/hdtwtv1usq
Just 8 Minutes of Exercise Cuts Mortality 36%
Get off dat ass. 8 minutes a day of vigorous exercise linked to a 36% lower mortality risk. Benefits start at 2.2 min/day. https://t.co/UQlUv8NHI7
De Novo Enzymes Redefine Peptide Therapeutic Production
Peptide therapeutics are powerful. But making them has always been difficult. Traditional chemical synthesis can involve long routes, poor selectivity, and significant environmental impact, while biological production is often limited by the pathways evolution happened to provide. What if we could design...
HSV-1 Reactivation Linked to Faster Aging, Dementia
The reactivation of herpes simplex virus (HSV-1, not only herpes zoster) may be tied to accelerated aging and dementia, and account in part for the mechanism of Shingrix vaccine''s protection @WIRED https://t.co/iKF1JcYSu0
Gut Microbiome Proteins Influence Aging Speed, Metabolic Disease
Links between gut microbiome proteins and pace of aging, metabolic diseases, and medications @Cell_Metabolism https://t.co/Vg6vMPjnXm https://t.co/3SKNH6IEhJ
China Passes Law Accelerating Environmental Ambitions, Defying Expectations
Meanwhile, shockingly, the other major global power is doing the very opposite within its own borders... https://www.bloomberg.com/news/articles/2026-03-13/china-s-new-law-signals-xi-won-t-curb-environmental-ambitions
Chirality: The Key Hidden Ingredient for Life
Life's Hidden Ingredient 💥 See full video here: https://t.co/VXWXNHRiyO #science #abiogenesis chirality - Also called: dissymmetry. the configuration or handedness (left or right) of an asymmetric, optically active chemical compound https://t.co/zi6zYW7RtE
Biologists Wielding AI Will Outpace Those Who Don’t
1/ AI won't replace you. But a biologist using AI will. Especially in bioinformatics, where the questions never stop coming. https://t.co/ckfZWjnei3
CBD and CBG Reverse Fatty Liver in Mice
I teach medical students that fatty liver disease (MASLD) affects 1 in 3 adults and has limited approved drug treatments. That may be changing. Hebrew University researchers found CBD and CBG -- two non-psychoactive cannabis compounds -- reversed fatty liver in mice...
AGI's Impact Will Outpace Industrial Revolution Tenfold—Act Now
Demis Hassabis told world leaders: AGI will be 10x the impact of the industrial revolution at 10x the speed. There's no way around it besides taking action now.
Torrential Rains Trigger Deadly Ethiopia Landslide, 65 Dead
A landslide in Ethiopia’s southern Gamo region after days of torrential rain led to the deaths of at least 65 people, according to a government agency https://t.co/XLqySClq1s