Methionine Restriction Cuts Alzheimer Pathology via FGF21 Signaling
A study in Alzheimer's & Dementia found that late-life methionine restriction reduces Alzheimer’s pathology and neuroinflammation in mice by activating the liver–brain FGF21–FGFR1 signaling pathway, independent of metabolic improvements. 🧠 https://t.co/A9kEqNv8pO
Semaglutide Boosts Metabolism, Reduces Anxiety in Obese Mice
Beyond the Weight Loss: The Effects of Semaglutide on Standard and Diet-Induced Obese Mice 🤔"..semaglutide improved glucose metabolic health inboth diet groups..while chronic semaglutide treatment appeared to exertanxiolytic effects in obese mice, opposit[e] effects were observed in lean animals.." https://t.co/doU6EkwT7z
Vitamin C Blocks Ferro‑aging, Boosting Longevity in Primates
Simple nutrients, serious science. March 2026 is turning into a good month for longevity research on everyday supplements. First, a Nature Medicine paper (COSMOS trial) showing daily multivitamins modestly slowed epigenetic aging clocks (GrimAge and PhenoAge) in older adults: around...
Chili Capsaicin Restores Gut-Brain Link, Boosts Memory
Eating chilis may be good for your memory. Capsaicin (from chilis) partially rescued the memory decline by restoring the gut-brain (vagus-hippocampus) communication. Aging microbiome disrupts the gut-brain communication and memory function. https://t.co/gAEPdmhPDB
Machine Learning Advances Practical Quantum Error Mitigation
Thank you to everyone who packed the room this morning at #APSSummit26 for my 30 min talk on our machine learning for practical quantum error mitigation (Nature Machine Intelligence) work. https://t.co/na3tJ45loA
AI May Soon Run on Living Brain Cells
AI infrastructure may be heading somewhere unexpected. Researchers are now exploring “wetware”, computing systems powered by living human brain cells instead of traditional silicon. The idea sounds like science fiction, but experiments in biological computing are already underway. If brain cells can process...
Stars Shine Their Most Beautiful Light at Death
Join us as we talk about how stars experience exquisite beauty in their final moments.
Hunting Still Central to Human Evolution, Says Ed Hagen
Anthropologist Ed Hagen @ed_hagen debunks the debunking on the role of hunting in human evolution.
Share Your Vision for an Abundant Future
This is what we do at The Future Vision XPRIZE, send us your ideas, show us an abundant future
Warming Sped up After 1980s, Not in Last Decade
"Why global warming is accelerating & what it means for the future" [note: the rate of warming increased in the '80s as sulphate aerosols subsided but claims it has accelerated over the *past decade* are not supported IMO] by @AlecLuhn...
Gut Bacteria Shift Triggers Age‑Related Memory Decline
Memory Loss Starts in the Gut As a medical school professor, I was taught that memory loss is a brain problem. New research from Stanford says it's a gut problem. Scientists just identified a 3-step pathway from gut to brain that drives age-related...
GenAI Predicts Insulin Resistance Using Wearables and Routine Labs
Innovation with genAI, predicting insulin resistance from wearable device data (for steps, heart rate, sleep) integrated with demographics and routine blood parameters. Without CGM. @aametwally1 @GoogleResearch @NatureMedicine https://t.co/PRZPLGjuxZ https://t.co/ShbFyO55qP
Structure's GLP-1 Pill Shows Best-in-Class Obesity Results
Structure’s GLP-1 pill shows ‘best-in-class’ potential in obesity trial https://t.co/j0fzAg6GRV @ByJonGardner $GPCR $LLY $NVO $AZN $MRK #obesity
City‑Killing Asteroids: The Real Threats to Earth
The asteroids we should actually be worried about, the city killers… #space #asteroid #nasa #science #astrokobi
Chinese Astronauts Install Debris Shields During 7‑hour Spacewalk
Astronauts Zhang Lu and Wu Fei made a spacewalk from the Chinese Space Station from about 0430 UTC until 1135 UTC Mar 16, continuing installation of external debris protection panels https://t.co/GKPg66uFEF
Multi-Ancestry Polygenic Score Predicts T2D, Obesity, GLP‑1 Need
A polygenic risk score that predicts Type 2 diabetes, obesity, and likelihood for requiring a GLP-1 drug. Across 6 ancestries. https://t.co/5hTVv8kqlK https://t.co/IgXhx8vFA6
A Century-Old Secret Space Dream Ignored by Everyone
100 years since someone had a crazy idea and believed in it. Only Goddard, his wife Esther, and a couple of assistants witnessed it. It didn't even make the local newspapers, and Goddard kept details secret for years afterward due to...
Low‑level Cell‑phone Radiation Could Boost Health
Hormesis in action if this study proves correct - a little bit of cell phone radiation may be good for you.
AI-Driven Digital Biology Delivers Custom Cancer Vaccine for Dog
The era of digital biology, exemplified by making a bespoke and effective vaccine for cancer in a dog, is taking off. Access to the AI-Coscientist. A new feature @NatureMedicine https://t.co/AR9lqne7E1
Placenta: Century‑Old Medical Resource Beyond Waste
Actually yes. The placenta has been used in medicine for over 100 years. The amniotic membrane is used in eye surgery for corneal reconstruction. It's used as a graft for burn treatment and wound healing. It's used in dental and orthopedic...
Distinguishing Fact From Opinion in Science Textbooks
Opinions or Facts in Textbooks 💥 See full video here: https://t.co/VXWXNHRiyO #abiogenesis #chemistry #education https://t.co/lKzo8AldPs
Progress MS-31 Undocks From ISS Poisk Module
The Progress MS-31 cargo ship undocked from the ISS Poisk module at about 1324:12 UTC Mar 16
Aged Blood Stem Cell Mutations Drive Aortic Aneurysm Growth
Just weeks ago we didn't know that mutant clones of our aged blood stem cells could be linked to expansion of an aortic aneurysm. No less how. And so much more https://t.co/YuEmJPkdg2 https://t.co/qQq2dgAfWf
Ehrlich's Doom Forecasts Proven Wrong by Metal Prices
RIP Paul Ehrlich who made a string of famously apocalyptic predictions in the 1960s and 70s (mass starvation, etc). In 1980, Ehrlich bet Julian Simon that five key metals would rise in price. They didn't. https://t.co/xxFt2N6ptJ
Sarepta Tests Elevidys Safety, Sana
Sarepta tests new Elevidys safeguards; Sana advances diabetes cell therapy https://t.co/hkixuANCCV $SRPT $SANA $INO $BAYRY #biotech
Low‑Carb Diets Linked to Higher 10‑Year CVD Risk
Association between Low-carbohydrate Diets and 10-year Atherosclerosis Cardiovascular Disease Risk: Data from the National Health and Nutrition Examination Survey https://t.co/NavY2Ldwip https://t.co/Is80ZwaTXu
Could Reduced Sperm Motility Signal Natural Conception Limits?
Interesting. I wonder if decreased motility is associated with other abnormalities? Could decreased motility be "nature's way" of limiting conception?
Structure's Obesity Pill Shows Phase 2 Weight‑Loss Promise
Pretty impressive data from $gpcr, which remains my favorite ticker. Structure's obesity pill shows weight loss promise in Phase 2 trial https://t.co/T0JU2UuftY
Statkraft CEO Warns Price Tweaks Threaten Clean‑energy Investment
European regulators should avoid adjusting electricity pricing in case it puts at risk investment in clean energy, according to the CEO of Statkraft https://t.co/J5F9UAE4oH
Aging Can Be Treated, Says Harvard Scientist Sinclair
The scientist trying to reverse aging in humans: David Sinclair. This Harvard researcher spent 30 years studying aging—and now says it's a treatable medical condition. He reveals how on the World Governments Summit: https://t.co/VRgBFtCiRW
Intermittent Calorie Restriction More Feasible for T2D Patients
The effect of continuous or intermittent calorie-restricted diet on body composition and 2 resting energy expenditure in patients with type 2 diabetes "both diets appear promising, with a lower 60 dropout rate in ICR suggesting greater feasibility..." https://t.co/sPAkTrVK40 https://t.co/C82NXBEddG
Artist Electrifies Paintings with Rice Lab’s Graphene
📰 🧪 James Tour Group in the News: Artist uses Rice lab’s laser-induced graphene to electrify his artworkAn article featuring Joseph Cohen’s artwork mentions that it was created […] https://t.co/fJ0GKOoOtz
Eccentric, Not Isometric, Contractions Drive Sarcomere Growth
Since eccentric contractions produce passive mechanical tension, they stimulate sarcomerogenesis, which we observe as increases in muscle fascicle length in humans. Isometric contractions at short or moderate muscle lengths do not. https://t.co/7wVgBzjELC
Cell Painting Images Predict Cellular Age Without Methylation
A model that predicts cellular age from Cell Painting microscopy images alone. No DNA methylation needed. The model captures morphological aging hallmarks across nuclear and cytoplasmic compartments, correlates with chronological age AND epigenetic clocks. The promise: screen for rejuvenation compounds...
Single‑cell Methylation Reveals Age
Epigenetic aging happens at different rates in individual cells within the same tissue. Using single-cell DNA methylation analysis, Hagit Masika, Tommy Kaplan, Howard Cedar, and colleagues show polycomb CpG island methylation creates 'young' vs 'old' cell subpopulations even at fixed...
Red Meat in Plant-Forward Diet Impacts Aging Biomarkers
Effects of Minimally Processed Red Meat within a Plant-Forward Diet on Biomarkers of Physical and Cognitive Aging: A Randomized Controlled Crossover Feeding Trial https://t.co/hpjHcUsbtP https://t.co/Kf2yZhbmVe
Aging Driven by DNA Instability and Mitochondrial Decline
So great to see the OG work that helped spark the longevity revolution taken to the next level: New paper confirms two main causes of aging: 1. DNA instability -> epigenetic noise 2. Mitochondrial decline ...independently causing failure of the cell Is this relevant to...
Judith Curry Led Trump‑appointed Group to Undermine EPA Science
#JudithCurry was a key member of the "unlawful" working group tasked by the Trump administration with discrediting the science underlying the EPA endangerment finding (the legal basis for regulating carbon emissions).
Nicotinamide Study on Amyloid Beta Retracted Over Editing Concerns
FYI - Retracted paper in the NAD field: Nicotinamide Ameliorates Amyloid Beta-Induced Neurodegeneration in Adult Mouse Brain. The editors lost confidence in the findings after "indications" of inappropriate editing & partial duplication https://t.co/WVJBCeKjQ4 https://t.co/lmUObhFxcK
Graph AI Accelerates Longevity Drug Discovery in New Alliance
Solve Aging: Biophytis and LynxKite are expanding their alliance to use graph-based AI to speed discovery of new longevity drugs, aiming to map complex aging biology and surface novel targets for age-related disease. The “AI x longevity” stack is quietly...
Genetics Shapes Smoking Habits, Recovery, and Free Will Beliefs
“Everything is related to your genetics, both your smoking and your quitting smoking, both your addiction and your recovery. Even your belief in free will is heritable and is more similar in identical twins.” — @kph3k 🔗 https://t.co/BxddkybDz0 https://t.co/LxTwp2vXIX
GLP‑1 Drugs: Promising yet Unproven Healthspan Extension
GLP-1 drugs for extending healthspan? Intriguing but we're a long way off from evidence Discussed at length in Super Agers as a candidate drug beyond lifestyle + factors @TheEconomist gift link https://t.co/A2dpfcnApF https://t.co/3gY8iACeGs
EPA Outperforms DHA in Sleep‑deprivation Cognitive Decline
Dietary EPA shows superior efficacy over DHA in chronic sleep deprivation-induced cognitive decline by disrupting the crosstalk between intestinal ferroptosis and gut-derived Aβ production 🧠👨🏻⚕️ 🔗https://t.co/rqUO058bO9 https://t.co/Kr137l2BvH
Breast Milk Shifts Daily: Match AM/PM Feedings
Breast milk has a clock. Morning milk has higher cortisol and stimulating amino acids to help the baby wake up. Evening milk has more melatonin and nucleotides that have a sleep inducing effect on the nervous system to help the baby...
Exercise Boosts BDNF, Enhancing Brain Plasticity
Exercise increases brain-derived neurotrophic factor, supporting brain plasticity. Trends in Neurosciences, 2002. Cotman and Berchtold https://t.co/jux3TwN0fS
High FSH, Not Low Estrogen, Drives Cognitive Decline
Follicle-stimulating hormone linked to cognitive decline and amyloid burden in postmenopausal women 👉"Elevated FSH, not low E2, is linked to cognitive decline and Aβ pathology in postmenopausal women." https://t.co/EkFxbjsao9
Immigrants Powered Moon Landing and Modern Chip Revolution
"We were doing just fine without immigrants" is a commonly repeated trope. Just to to take the examples listed and the immigrants who made essential contributions... Landing on the moon: Wernher von Braun (Germany) → Chief architect of the Saturn V rocket, the...
Seabird Guano Boosts Plant Growth, Stabilizes Coastal Dunes
Seabird guano accelerates plant growth on barrier islands, enhancing dune formation and aiding recovery from coastal erosion, highlighting the ecological role of birds in shaping and stabilizing vulnerable coastal landscapes. coastalecology
The Placenta: A Temporary Powerhouse Organ We Overlook
The placenta is honestly the most remarkable organ. A woman's body grows it from scratch in a matter of weeks. By week 12, it's the size of a dinner plate and fully functional. It produces its own hormones like progesterone, estrogen,...
Explore Human Organs in 3D Down to Single Cells
This stunning 3D map lets anyone explore real human organs down to a single cell | BBC Science Focus Magazine https://t.co/32o3aJrrZB