Hookworm Vaccine Achieves Near‑100% Protection in Phase 2
Some exciting news tonight just published @TheLancetInfDis our @TexasChildrens @BCM_TropMed @GWSMHS hookworm anemia vaccine is showing high levels of protective immunity in human phase 2 clinical trials, nearly 100% reduction in hookworm, a project of decades https://t.co/C23cNdsa0p
AlphaFold Adds Millions of Complexes, Illuminating Protein Interactions
Millions of protein complexes added to AlphaFold Database shed light on how proteins interact https://t.co/Kt9oFFkAf2 https://t.co/tEnlYOTCPl
EVs Saved 2.3 M Barrels Daily, Could Double by 2030
EVs helped avoid the use of 2.3 million barrels of oil daily last year. By 2030, that number could more than double to 5.25 million barrels https://t.co/ipPiTXbIvV
Quantum Processor Yields 2.44 Å Distance via ZNE
Sharing a snapshot from my second talk at #APSSummit26 — this one on NMR OTOCs and Pauli‑path approaches to zero‑noise extrapolation (ZNE) to learn an inter-atomic distance of 2.44 +- 0.04 angstroms on a Google's Willow quantum processor. https://t.co/350lCfheQM
Chickenpox Spreads Airborne, but Not via Spit Droplets
You would think that the chickenpox virus being airborn would mean “little drops of spit in the air” since that’s how most viruses do it. Alas. That is not how chickenpox goes airborn 😬
Largest Review Finds No Evidence Cannabis Relieves Anxiety, Depression, PTSD
No evidence that medicinal cannabis effectively treats anxiety, depression, or PTSD - according to the largest review of cannabinoids ever conducted.
One Short Telomere Triggers Senescence and Instability
Researchers using Saccharomyces cerevisiae showed that replicative senescence is triggered when a single shortest telomere falls below a critical length, which both initiates senescence and promotes genomic instability that can transiently enable cells to escape it. 🧬 https://t.co/TOUeXB4L3v
AI's Real Bottleneck: Accelerating Human Processes, Not Tech
Our bottleneck for some of the biggest change ahead may be humans. I shared the story of Paul Conyngham and his dog Rosie on my Instagram when it broke. When I read the coverage, my shock was less that ChatGPT...
Healthy Life Extension: Geroscience’s Guiding Principle
Healthy Life Extension: The “North Star” of Geroscience🌟| @AgingJrnl 🩺 - David Barzilai MD PhD | @agingdoc1👨⚕️ 🔗https://t.co/JqhGgOe3nA https://t.co/ieBQZ6pAQd
Feedback System Enhances Gait and Perception in Knee Prostheses
This week's Editor's Choice highlights a study by Valette and colleagues that evaluates a feedback system to improve gait and perception when using a knee prosthesis. @rlvalette Learn more in Science #Robotics: https://t.co/pWQ3r6aGLs https://t.co/xqUZp2YyCH
Complement Proteins Predict Dementia Risk over a Decade
Adding complement proteins to the blood testing schedule is in the arena Systemic complement factors in aging, Alzheimer’s disease and other dementias: a longitudinal study over 10 years https://t.co/qDwmnbxHHY
Cochrane Review Misses Intermittent Fasting’s Metabolic Benefits
A new Cochrane review claims intermittent fasting "doesn't work." But it only measured weight loss - not insulin sensitivity, autophagy, inflammation, or gene expression. Here's what the science actually shows. The 2026 Cochrane systematic review analyzed 22 randomized controlled trials and...
Aging Genetics Pioneer Tom Johnson Passes, Legacy Endures
Thomas Eugene Johnson The field of aging genetics lost one of its pioneers. Tom Johnson's identification of the age-1 mutant allele in C. elegans was a landmark moment, showing that a single genetic change could dramatically extend lifespan. That discovery helped...
GIP Drives Subcutaneous Fat Storage; Tirzepatide Leverages This
GIP preferentially enhances glucose storage and triglyceride deposition in healthier subcutaneous fat, particularly under conditions of hyperinsulinemia and hyperglycemia. Tirzepatide contains a GIP agonist. https://doi.org/10.2337/db10-0098 https://www.gatlan.com/ @GatlanHealth
World's Largest In‑Vivo CRISPR Data Engine Unveiled
From Prof Jin and my colleagues @scrippsresearch the largest in vivo CRISPR data engine, nearly 8 million cells, in collaboration with @nvidia and featured at GTC
Pfizer's Ibrance Successor Advances with Fresh Study Data
Pfizer’s Ibrance successor moves forward with new study data https://t.co/ozXAZYmc3M by Kristin Jensen $PFE $LLY $NVS $RHHBY $ONC
GLP‑1 Weight Loss Shows No Extra Muscle Loss
A study asserts lack of disproportionate loss of muscle mass or strength cf weight loss from GLP-1 drug treatment, in mice and a small short term (12 weeks) trial in men The issue remains unsettled and counters the efforts by companies...
Microplastics Detected in Every Tested Placenta, Threatening Newborns
It is honestly scary that microplastics are now being found in human placentas, amniotic fluid, breast milk, and even testicular tissue. A 2024 study found microplastics in every single one of the 62 placentas they tested. The plastics in your...
Navigating Climate Science Amid Growing Uncertainty
Horizons Podcast: Climate Science in an Age of Uncertainty | My recent conversation with @PennSAS Dean Mark Trodden https://t.co/8Ocy4Bk1Tg
Believing You’re on Steroids Increases Strength Significantly
You should placebo yourself into thinking you’re on steroids. Athletes given a placebo they thought was Dianabol added ~8.5 kg to their bench, ~7 kg to their military press, and ~16 kg to their squat in 4 weeks compared to when...
Single-Cell Analysis Advances Neurodegenerative Disease Understanding
Neurodegenerative diseases at the single-cell level, a powerful tool to differentiate and better understand https://t.co/Pkz4qW0ELM @jclinicalinvest https://t.co/LiJ4FojRYZ
Co‑varying Residues in MSAs Predict Protein Contact Points
A great read: What we can learn from evolving proteins "A signal hidden in Mulitple Sequence Alignments (MSAs): amino acid positions that tend to co-vary in the MSA tend to interact with each other in the folded structure, often via direct...
Meteorite Crash in NE Ohio Leaves Everyone Unharmed
NE Ohio just got hit with a meteorite, heard it from all over .. I think it was a truck unloading by our house. Looks like everyone's OK
Hidden Mistakes, Not Bad Data, Threaten Genomics
1/ You think the biggest danger in genomics is bad data. More than that. It's the mistakes you make—without knowing. Here are the ones I learned the hard way. 🧵 https://t.co/3oj9cseVq7
Biology Leaders Tackle Alzheimer Research Reproducibility Crisis
For decades, they’ve set the record straight in biology. Next up: science’s reproducibility crisis A new coalition of biology grand challenge organizers will assess Alzheimer’s literature https://t.co/nLX1g0EEcB
Elastic Tissues Store and Release Energy Within the Body
Elastic tissues aren't isolated; they're part of a messy, damped, energy-leaking body. What they do is store a chunk of it temporarily as stretch, twist, or shear then dump it back out as recoil.
FreezOpt Controls Ice Nucleation, Preserves Cells in Cryopreservation
I've always been fascinated by animals that can survive being frozen—cell walls are delicate and can be destroyed by ice crystals. HOHCells just launched FreezOpt, which is designed to keep cells intact during cryopreservation. It enables controlled initiation of ice...
Mechanical Forces: Emerging Tools for Diagnosis and Therapy
Mechanical forces play essential roles in biology. Measuring and controlling these forces represent emerging strategies for disease diagnosis and therapeutic intervention, to complement more traditional approaches. This review article, published today in Nature Reviews Bioengineering (https://t.co/byKGFuVFLH), summarizes the status of...
Open‑Source AI Agent Automates Physics Research End‑to‑End
Physical Superintelligence dropped Get Physics Done, an open-source AI agent that can scope research problems, run experiments, verify results, and draft papers https://t.co/0gDAIMmxe7 #ArtificialIntelligence #Innovation #Technology #Tech #TechNews https://t.co/nudT0C4wXm
New Drug Could Eradicate Sleeping Sickness, Says NPR
Sleeping sickness could be wiped out with this new drug: my comments @NPR @NPRGlobalHealth https://t.co/T0mAeX8P0A
Can NAD⁺ Manipulation Extend Human Healthspan?
NAD for Health: Opportunities & Challenges 2026 This international conference will explore a central question in aging research: can manipulation of nicotinamide adenine dinucleotide (NAD⁺) metabolism enhance human healthspan and prevent age-related diseases? https://t.co/bEtQPmUnSh
Modified Lipid Nanoparticles Boost Immunity and Cut Vaccine Inflammation
Engineered lipid nanoparticles with modified ionizable lipids enhance immune cell metabolism, improve mRNA vaccine delivery to lymph nodes, and reduce inflammatory side effects in preclinical models. vaccinetechnology
Observations Show Universe Is Flat Despite Einstein’s Curvature Possibilities
Einstein showed space can curve, but data reveals a flat Universe According to Einstein, space can take on any curvature depending on what's in it: positive curvature, negative curvature, or zero (flat) curvature. So why is our Universe so flat? https://t.co/fyjYOnXs1d
AI + Chemistry Boosts Bio‑Oil Yield Predictions
Thrilled to share that I’m a co-author of a newly published paper in Scientific Reports — a Nature Portfolio, Q1-ranked journal — highlighting the power of AI-driven innovation in sustainable energy systems. Our paper, “Deep learning enhanced prediction framework for bio...
Mars Missions Hinge on 26‑month Launch Windows
𝗠𝗮𝗿𝘀 𝗶𝘀𝗻’𝘁 𝗷𝘂𝘀𝘁 𝗮𝗯𝗼𝘂𝘁 𝗯𝗶𝗴𝗴𝗲𝗿 𝗿𝗼𝗰𝗸𝗲𝘁𝘀. 𝗜𝘁’𝘀 𝗮𝗯𝗼𝘂𝘁 𝘁𝗶𝗺𝗶𝗻𝗴. One thing that always fascinates me about space missions is this: SpaceX’s Starship does not fly to Mars in a straight line. It follows a Hohmann transfer orbit, an elliptical path around the Sun that...
Non‑local Fatigue Stems From Central Nervous System Fatigue
Non-local fatigue is closely associated with reductions in voluntary activation of the untrained limb, indicating that it is caused by central nervous system fatigue mechanisms. https://t.co/BSr0Cw5Qz6
Human‑Driven Peatland Fires Surge, Boost Global Carbon Emissions
Charcoal records indicate a sharp rise in wildfires across Southeast Asian and Australasian tropical peatlands during the 20th century, likely driven by human activity, with significant implications for global carbon emissions. climatechange
ADHD Adults Show Sleep‑Like Brain Activity During Focus
Adults with ADHD display increased sleep-like brain activity during attention tasks, which correlates with more frequent lapses, slower reactions, and greater sleepiness compared to neurotypical adults. adhd
Nvidia Launches Orbital AI Chip to Bypass Earth’s Energy Limits
Nvidia announces Vera Rubin Space-1 chip system for orbital AI data centers “Orbital data centers have been an increasingly popular proposition as AI demand tests Earth's energy constraints.” https://t.co/fWrKyLiAij #SpaceEconomy https://t.co/SBqD6vmYbz
Sagan Warned Congress: Climate Change Escalates Exponentially
If you haven’t watched this before, you should. The brilliant Carl Sagan testifying before the United States Congress in 1985 on #ClimateChange. We should have listened then. Will we now? Climate change isn’t an on & off switch. It’s an exponential dial....
Exploring Known and Unknowns in NAD Coenzyme Research
looking forward to concluding next week's NAD for Health conference in Copenhagen with a talk on Known Knowns and Known Unknowns in NAD Coenzyme Research.... see you there https://t.co/hLAnAq7Fay
Day 1 Highlights From APS Global Physics Summit
🧪⚛️ A brief write-up of random highlights from Day 1 of the big annual APS Global Physics Summit (formerly known as the March Meeting). https://t.co/tO5dvFZm3Q
Pakistan's Solar Surge Buffers Fossil Fuel Price Shock
Pakistan’s rapid adoption of solar power in the past few years is helping cushion the impact of a surge in fossil fuel prices due to the Middle East war https://t.co/4eyTCuM5KW
Women Comprise Two‑thirds of Alzheimer’s; Midlife Origins Examined
Why do women account for nearly 2/3rd of all cases of Alzheimer's disease? A new, thorough review @jclinicalinvest, open-access, on its origins in midlife. https://t.co/obITwhEiYG https://t.co/RXBffM9jKV
Great Conversations Synchronize Brains and Bodies
Science just explained what's actually happening in your body during a great conversation. When two people are truly in sync, their bodies and brains are literally starting to function alike, and that's exactly what great communication is designed to do....
Cool Buildings by Sending Waste Heat Into Space
Air conditioning is an energy hog, right? Right. But there are also incredibly low-energy ways to cool buildings - by literally sending their waste heat into space.
Aged Amygdala Reacts to Refined Diets, Not Fat or Sugar
The aged amygdala’s unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis https://t.co/0eVLV5Kual
Brazil's New Climate Plan Hinges on Halting Deforestation
Brazil's revised climate plan focuses on stopping deforestation as the key to driving down emissions https://t.co/Zvg9D2XifC
Defending Paul Ehrlich's Legacy Amid Smear Campaign
Since some of the most horrid individuals on this medium are working hard to smear Paul Ehrlich on his passing, here's some relevant background on Paul and his legacy from "The Hockey Stick & the Climate Wars" (https://t.co/y6lplWKpsL) https://t.co/Zu3kNa9C0E
Broken Chromosomes Repaired with Fragments Spark Cancer‑driving Mutations
Researchers at Cardiff University found that severe DNA mutations called chromoanasynthesis happen when broken chromosomes are repaired using small DNA fragments, causing chaotic duplications that can drive cancer and genetic diseases. 🧬https://t.co/Q9j2hRezTs