Gene Therapy Delivers Real Results Amid Hype
Katrine Bosley: There's no question “hopes and aspirations” got ahead of the pace of any new science on gene editing #STATBreakthrough Seng Cheng: “The promise of gene therapy is correct. I think it has made that promise. and that's demonstrated by the few and grueling approvals that we've seen that are truly transformative for our patients.” $AZN
Runaway Climate Feedbacks Unlikely; Earth Differs From Venus
There is a lot to worry about with climate change, but "runaway" feedbacks are not one of them. Good piece by Andrew Dessler over at The Climate Brink on how climate feedbacks work and why the Earth is different from...
China Produces Triple U.S. PhDs, Boosting Biotech Innovation
$BIIB’s Jane Grogan on the impact of China on biotech innovation. “There's three times more PhDs that have been given last year in China than in the US. ... That's a lot of bright young things out there who are going...
Breakthroughs Take Years, Then Appear Overnight
$BMY chief scientist Robert Plenge: says there is “a joke” drug developers often repeat. “It's an overnight sensation a decade in the making. These things can actually be going on for a very long time, and then suddenly the field catches...
Four Biomarkers Can Meaningfully Assess Coronary Artery Disease Risk
The 4 biomarkers to meaningfully assess a person's risk of coronary artery disease @rayshafarah @aklfahed @pnatarajanmd @JACCJournals @uk_biobank https://t.co/CPfBPVRENq https://t.co/xTlj2ykr45
Oral Ozempic Trials Fail to Show Alzheimer's Benefit
The negative oral Ozempic randomized trials (EVOKE, EVOKE+) for Alzheimer's disease have now been published @TheLancet https://t.co/Xx0YknTSC2
GLP‑1 Drugs May Protect Heart, Vessels, Kidneys in Type 1 Diabetes
GLP-1 drugs have established benefit for Type 2 diabetes. New data suggests that extends to Type 1 diabetes, with heart, vascular, and kidney protection https://t.co/nZDKHoFIRm https://t.co/lTHIgoj4ir
Testing Leeches for Boosting Testosterone and Sexual Function
Leeches to improve testosterone and sexual function. Will look into this and see if worth doing an experiment.
Consciousness Is a Full-Body Phenomenon, Says Damasio
I Feel, Therefore I Am – neuroscientist Antonio Damasio on consciousness as a full-body phenomenon https://t.co/F7gTEhWLHS
Human Bio‑Electricity and Fusion Deliver Unlimited Power
"The human body generates more bio-electricity than a 120-volt battery and coupled with a form of fusion, the machines had found all the energy source they would ever need."
April's Above‑Average Rain May Delay Corn Planting
🌧️A wetter start to U.S. spring planting? The Climate Prediction Center favors an above-average precipitation scenario across the U.S. Corn Belt for April. Planting delays could result pending the timing/intensity. Typically, about 25-30% of U.S. corn is planted by April 30. https://t.co/96Z1EtnnTx
Measles 97% Preventable; Vaccine Safer Than Supplements
I read from an influencer nurse that measles is “going around”. She is selling vitamin A supplements. Having measles is not inevitable. Especially if a population is vaccinated. And that has been proven in the US for the past 30...
Escalating Weather Extremes Signal Alarming Climate Trends
"The Weather Is Getting Wilder, and Some See a Dire Signal in the Data" by @dgelles for the @nytimes: https://t.co/vACrMvG2Tf
Quantum Fluctuations During Inflation Shape Cosmic Patterns
This was a very good question from Ryan - why does the Universe on the largest scales resemble the Universe on the smallest scales? The answer, for the case of the distribution of galaxies on the sky, is that the...
Most Papers Misinterpret P-Values; Here's a Clear Guide
1/ You probably don't understand p-values. And that's fine, because most published papers misinterpret them too. Here's what a p-value actually is, explained with a coin flip. https://t.co/jhTRVpP01k
ESA Restores Contact with Proba-3 Coronagraph After Month‑Long Silence
ESA Director General Josef Aschbacher says at a press briefing that controllers have just managed to restore contact with the Proba-3 coronagraph spacecraft, which had been out of contact since last month. Recovery efforts underway.
Higher Body Fat and Inflammation Raise Mortality Risk
Linking adiposity and inflammation with all-cause and cardiovascular mortality https://t.co/JXj1WDWHHx via @medical_xpress #health #lifestylemedicine #CardioTwitter #MedTwitter #hearthealth
A Fifth Force May Exist, Yet Detection Remains Elusive
The case for and against a 5th fundamental force of nature Looking for a fifth fundamental force of nature? It might be out there. But finding one is a much bigger challenge than any experiment or observation is up to, at least, so...
UN Climate Chief Discusses Research Future Post‑US Funding Cut
Jim Skea, chair of the UN’s climate science body, talks to Zero about the future of its crucial research after the US pulled its support https://t.co/oOxMOJw7jx
Master CNS Fatigue to Optimize Training Variables
Understanding how supaspinal and spinal CNS fatigue mechanisms work during exercise allows us to program training variables optimally . See more in this week's free Patreon article. https://t.co/6i4w1tPtdL
Nihon University's Tenkoh
Nihon University's Tenkoh-2 cubesat, deployed from the HTV-X1 cargo ship on Mar 11, has been cataloged as object 68261, in a 495 x 501 km x 51.6 deg orbit.
Voyager's 40,000 Mph Journey Reaches Just One
By Fushin whose photo is of Orion's belt, 1300 light years away. Voyager was launched in 1977 and traveled until last year at 38000 miles per hour and made it one light day... https://t.co/oLrjZfg0t4
Exploring the Path to Quantum Advantage at Kavli Symposium
I'm looking forward to the Kavli Symposium tomorrow at the APS Global Physics Summit, where I'll speak about "The Road to Quantum Advantage" https://t.co/PVExMVwgFr
Repowering U.S. Wind Farms Could Double Output to 21% Demand
New paper: Repowering existing U.S. wind farms with newer turbines could double current output so that the U.S. could meet up to 21% (instead of 10.5% currently) of electricity demand from wind. Paper: https://t.co/WSQ69VU0c5 Article https://t.co/aApXUcPvjp
New DNA Base Editor Cuts Off‑target Edits, Keeps Efficiency
A newly engineered DNA base editor significantly reduces bystander edits while maintaining high on-target efficiency, offering a more precise tool for gene therapy and genetic research. geneediting
AI-Driven Memory Chip Surge Threatens Semiconductor Climate Impact
A rush to boost to production of memory chips to meet accelerating demand from sectors like AI risks adding to climate cost of the semiconductor industry https://t.co/i5aUfKotIc
Unprecedented March Heat Wave Linked to Human‑Driven Warming
I'll be on @BBCWorld News America TONIGHT ~8pm ET to discuss the unprecedented March heat wave in the U.S. and its tie-in to human-caused planetary warming. Please tune in! https://t.co/bmgrFtoNpJ
Spacewalk Safety Tech Stuns While Working on Laptop
Doin some laptop work and watching the latest ISS space walk. Amazing how much tech goes into the safety of it. https://t.co/2vpLaqhNEd
All Human Diseases Emerge From Nature, Not Labs
Our government has gone full idiot. Every single human infectious disease, from smallpox and influenza to AIDS and Ebola, originally spilled into our species from nature. I know of zero exceptions to this rule (please enlighten me if you do) We don’t...
Stopping GLP‑1 Therapy Quickly Erodes Cardiovascular Protection
A new finding after stopping GLP-1 drugs in a large cohort with Type 2 diabetes: rapid erosion of CV benefit/protection New @bmj_latest by @zalaly @Biostayan https://t.co/JG6yB8wTJJ See thread: https://t.co/6JvfIIjVBw https://t.co/wUgWhvs9Yy
In‑body Genome Editing Promises Cheaper, Practical CAR‑T Therapies
What if we could engineer T cells in the body, making CAR T vs cancer, autoimmune diseases, and other applications far more practical, much less expensive? A step forward today via genome editing T cells https://t.co/FjgQA8NUlu https://t.co/XXk43WL1ac https://t.co/rpC7eCAlJH
Artemis II Rollback to Launch Pad Tomorrow at 8 PM
Artemis II SLS/Orion rollback to the launch pad is now set for tomorrow, Thursday, March 19, at 8:00 *pm.* It'll stream on NASA's YouTube channel.
Brain Organoids Play Video Game, Demonstrating Cellular Computing
It's the future it's possible that we'll use cells plus silicon for compute. In this experiment, scientists used a mouse brain organoid (brain-in-a-dish) to play a video game, showing living cells can solve digital tasks. Reaching 46% proficiency in a...
AI Agents Now Reliably Verify Physics Calculations
In late 2025, tools Like Claude Code crossed a threshold. Like hyperactive master's students, their physics calculations can now be made more reliable with domain expertise and some scaffolding. Check out Tobias Osborne's talk on using a swarm of...
Repeated Psilocybin Doses Yield 73% OCD Response
A randomized clinical trial of repeated doses of psilocybin for the treatment of obsessive–compulsive disorder 73.3% were responders (⩾35% reduction in YBOCS scores), with 40% in remission. These effects diminished but remained substantial at 6 months. https://t.co/tp2SPIKDrB
Logarithmic-Depth Quantum Circuits Efficiently Prepare Polynomial States
New #quantumcomputing preprint with @qubit_pharma team and CERFACS: "Logarithmic-depth quantum state preparation of polynomials" Check it out: https://t.co/DWGkoTImjK
5‑MeO‑DMT Shows Promise for Treatment‑Resistant Depression
Emerging evidence supports 5-MeO-DMT as a promising, ultra-short-acting psychedelic for treatment-resistant depression and other psychiatric conditions, warranting larger randomized controlled trials. https://t.co/6CcEOSat1F
Babies Rehearse Millions of Breaths Before First Air
We talk about a baby's "first breath" like it comes out of nowhere. It doesn't. Your baby has been practicing breathing for months before birth. Starting as early as week 10, your baby makes rhythmic breathing movements inside the womb. They're...
Mitochondrial Transfer Shows Promise Against Parkinson’s in Animals
Potential of mitochondrial transfer to prevent or treat Parkinson' s disease, in mouse and monkey models @CellCellPress https://t.co/c0oqfagddX https://t.co/KyBc1zQttc
Trillion Gene Atlas: Cool Concept, No Data Yet
Well, I love PacBio generally and the Trillion Gene Atlas sounds kind of cool. But as far as I can tell, none of this has been released publically and I cannot find a paper or preprint on the Trillion...
US EVA-94 Spacewalk Begins on ISS at 1246 UTC
Spacewalk US EVA-94 is underway on the ISS. Astronauts Meir and Williams, in suits 3015 and 3003 and with SAFER packs 15 and 18 depressurized the airlock past 50 mbar at 1246 UTC, opened the hatch at 1251 UTC and...
Compact Zero Modes Cap Entanglement Growth in Bosonic Systems
How compactness curbs entanglement growth in bosonic systems This work addresses a puzzling phenomenon in the study of entanglement in continuous quantum field descriptions. https://t.co/IxMegFdqnj #Zeromodes, understood here as degrees of freedom with vanishing confining frequency, play a central role in the #nonequilibrium...
Statistical Significance ≠ Biological Meaning in Bioinformatics
1/ Bioinformatics is NOT just statistics. The p-value is small, but is it biologically meaningful? Let’s talk. 🧵 https://t.co/gJ4s3Sjtr4
Neuromorphic Chips Could Make Data Centers Grow, Not Build
The human brain uses only 20 watts of power but performs ~1 exaFLOP (10^18 operations/sec). Today's top AI chips burn 700 watts for ~1 petaFLOP. We're still ~1,000x less efficient than biology. When neuromorphic chips close that gap, we won't...
Self‑cleaning Coating Lifts Solar Cell Efficiency 4.75%
Transparent superhydrophobic self-cleaning coating increases solar cell efficiency by 4.75% #energysky -- via pv magazine global: https://t.co/Vg3LeHCex1
CPT Symmetry: Nature’s Truly Unbreakable Rule
Why “CPT” is the Universe’s most unbreakable symmetry Some symmetries are always preserved, although things could be different if they weren't. But particle physics's CPT symmetry may truly be unbreakable. https://t.co/tcGehBgNs7
CO₂ Greening Boost Overridden by Heat, Water, Nutrient Limits
The "CO₂ greening story" is bad science @DavidUllrich202 It ignores the system Any growth boost is overwhelmed by heat, water stress, and nutrient limits. Net effect: weaker carbon uptake, not stronger. This is only "news" to those ignorant enough to be played...
U.S. Achieves Full Domestic Energy‑Storage Production Capacity
The US now has the production capacity to supply 100% of its energy-storage systems domestically https://t.co/WdSoY7xi2L
Astronauts Repair ISS Solar Arrays, Extending 2032 Mission
Today, high above your head, 2 human beings will be working outside in the eternal emptiness of the universe. astro_chrisw (1st spacewalk) & astro_jessica (4th) are improving solar arrays. Needed, as the International Space Station will be up & working through...
Storm Intensifies, Threatens North Queensland Mining Region
A major storm is strengthening off Australia’s northern coast, threatening to bring destructive winds and heavy rains as it heads for landfall in the North Queensland mining region later this week https://t.co/eQ4rvYd1y3