
Phase 3 Trial Tests Daratumumab Reg
.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/xv1RlCv8gl
Shift to Monthly Analytics, Transform Your Content Perspective
Looking at your analytics month by month instead of post by post is going to change how you feel about your content.

Workday Evolves Into AI Platform, Avoiding Shadow ERP
And @Gabe_Monroy shares the @Workday Bet in the AI era · Transforming the System of Record into a Platform for Agents · Turning Workday's Configuration, Data, and Processes Into Enterprise Rails for Al Agents · Letting Customers Move Fast on Al Without Building...

Teaching Models Confidence Reduces Overconfidence, Preserves Accuracy
How do top reasoning models become overconfident? MIT found that RL rewards correct answers w/o considering how sure the model is. By training them to estimate their confidence about each answer, the team boosted uncertainty estimates w/o hurting accuracy: https://t.co/zG3GskBc13
Winning with AI Requires Critical Thinking, Not More Agents
AI Agents are surging. So is Critical Thinking. Not a coincidence. Organizations winning at AI aren't the ones with the most agents. They're the ones who know exactly what to ask them. Critical thinking is becoming the rarest skill on the floor.
Google Cloud & DeepMind Bet Big on Voice Interactions
IMO: It's very interesting to see the approach that @GoogleCloud and the DeepMind team is taking with voice interactions. Very different from the classic #CCaaS approach. The DeepMind team is "very bullish" on voice interactions. #CIO #CMO #CX #Cloud #AI #GoogleCloudNext
Strong Quarter Misses Expectations, AI Growth Debate Persists
$NOW: in show me mode which makes the May 4th analyst day a big one. Q was strong w RPO g +23.5%, sub revs +19%, OM 31.8% - but expectations were higher and guide underwhelmed. Debate will continue...
Musk Could Acquire PayPal for $45B, Merge Into X
At $45 billion valuation - Elon Musk should just buy PayPal and integrate it into X (finally).
AI Potential Outpaces Adoption by Fivefold, Gap Likely Smaller
Based on an analysis of AI tools, the MIT Iceberg Index estimates ~11.7% of tasks could be done by AI vs actual adoption of ~2.2% (in terms of wage value). That suggests AI deployment is lagging what's possible by 5x. But...

Exploring Customer Acceleration with DeepMind on Google Cloud
Next up... a deep dive discussion about customer acceleration and DeepMind. #CIO #AI #Cloud #DeepMind #GoogleCloudNext @googlecloud https://t.co/eJ00fv7RSm

Beyond Clicks: 3‑layer Framework for AI Search Success
📊 A 3 Layer Framework to Measure AI Presence, Readiness and Business Impact: Redefining Metrics for the AI Search Era - A new guide where I cover: How the old organic search measurement model, built largely around rankings, clicks, and sessions,...
Live AI Workflow Demo: Repurposing Content with Claude
Doing an AI “show and tell” of one of my @claudeai content repurposing workflows on @superpathco at 11 CDT, come hang 👀
Backing Coherence Neuro's Real Solution for Glioblastoma
A great look at @coherenceneuro, a company we've been backing since 2024. Coherence is actually building something useful for a real market; the thousands of people who get diagnosed with glioblastoma - one of the deadliest brain cancers - each...
Choosing Between MCPs, CLIs, Skills, and Plugins
Confused by MCPs vs CLIs? Skills vs Plugins? You’re not alone. Having worked directly with all 4 teams, I break down: - Pros & cons of each protocol - When & where to use them - How to combine them...

Why Dale Vince’s Heat Pump Claims Are Wrong
There are literally 10s of thousands of reasons why Dale Vince is wrong about heat pumps and energy bills https://t.co/KR3JUI0Ujl https://t.co/O9qAbcNLk9
Growth Beats Cash Flow in Rule‑40 Valuations
There are lovers and haters of the Rule of 40. But if you fit the Rule of 40 profile, you will command a premium valuation multiple. Their latest post states "that companies with similar Rule of 40 but growing faster...

Tesla AI Strategy and Q1 Highlights on BBC
Great to be on @BBCWorld with @BenThompsonTV discussing Tesla’s AI Path and the 1Q takeaways 🎯🍿🐂📺 @BBCBreaking @BBCNews https://t.co/mdJQBGacLU
Free Tool Turned 8‑figure ARR After Pricing Demand
Ev Kontsevoy gave Teleport away free as a lead magnet for his paid product. Customers kept calling asking to pay for the free tool anyway. After five requests he put a price tag on it. Teleport Enterprise had almost no...

ML Model Builders Must Expand Beyond Pure Modeling
If your job is "I make the ML model", your job is cooked. You need to become more than that. This is how:
Build Invisible UIs: Prioritize Agent-First Interfaces
we've spent years trying to get people off of ramp. cards that enforce policy without a portal. receipts via text. memos and categorizations generated in the background. the best experience of ramp has always been the one you don't see. the...

Stop Over‑crafting Prompts; Learn to Work with AI
If you're still trying to craft the perfect prompt for your favorite generative AI chatbot, you're doing it all wrong. Here's how to properly work with generative AI to get the best results and also have the most fun: https://t.co/xG88ex2ZOD...
Starlink Posted $4.4B Profit on $11.4B Revenue
Starlink last year: $4.4 billion in operating profit and $11.4 billion in revenue, according to @Reuters review of pending S-1 https://t.co/e9KFllMATS
Starlink Mobile Launches in Canada, Philippines, New Zealand June
"Starlink Mobile service will be sequentially available in Canada, the Philippines, and New Zealand beginning in June" https://t.co/dM7tKUH308

Building Apprentice Pathways for Tomorrow's AI Workforce
I hope you can join me at tomorrow's discussion - Tomorrow's Workforce: Apprentice Pathways for the AI-Driven Organization https://t.co/znyc8k1HIp #AI https://t.co/H115SjcJ9N

Google Cloud Accelerates Agentic AI with Analyst Q&A
Here we go... Analyst Q&A with @ThomasOrTK. These Q&A sessions are one of the hottest tickets. @GoogleCloud is making significant inroads leverage their expertise in cloud into the agentic AI space...and beyond. #CIO #CX #AI #Cloud #GoogleCloudNext https://t.co/hthasip7UW
Local LLMs Won’t Need 16GB VRAM—Use Cloud
By end of next year. End of year after for 16gb vram. Do folk really need more for most things? Not really. But just call the cloud models when you do.
Marketing Must Shift From Off‑Site to On‑Platform Trust
The old internet trained marketers to get people off platforms and onto our sites. The new internet mostly rewards the opposite: say it here, prove it here, build trust here. But a lot of marketing teams are still optimizing for a world...
Linde's Gas Supply Could Power Future Space Launches
This was a good conversation between @JRogrow and Krzysztof Smalec on Linde. The opportunity in providing gases for space launches is an interesting one. https://t.co/a7vSbYo3cf
Contextual Lock‑in Gives Google Workspace AI a Competitive Edge
. @GoogleWorkspace Intelligence announcement is really a strategic argument: context beats capability, and the suite that knows your projects, your stakeholders, and your history becomes harder to leave. No outside model can replicate what it has accumulated. That is the...

Samantha Cristoforetti Captured Inside ISS Cupola
I love this photo of Samantha Cristoforetti inside the ISS Cupola module. Source: @NASA https://t.co/iQcuBLedWR

Governance Success Starts with People, Not Tools
Most data governance projects fail because they start with the tool. Not the process. Not the people. Colruyt Group flipped that: they aligned roles, tested the model, then scaled In the AI era, governance isn’t control—it’s enablement. by @ronald_vanloon, Grimme Bogaerts & Martijn...
Close B2B Deals by Targeting Every Stakeholder
Here's how most B2B deals die: - Your champion loves you - They take it to their boss - Boss asks questions they can't answer - Deal stalls - Finance asks for ROI proof - Nobody has it - Deal...
Amazon Teams with Grow Therapy for Employee Mental Health
Whoa... The employer behavioral health wars are heating up! Amazon is partnering with Grow Therapy on EAP. 👇 https://t.co/jVDA2xBhsE

Tech Giants Converge on AI‑Biology at SynBioBeta 2026
Silicon Valley's biggest tech players aren't just watching synthetic biology from a distance. They're showing up in person. This year at @SynBioBeta 2026, delegations from @Amazon, @Google, @Apple, @OpenAI, @Anthropic, @NVIDIA, and others are coming to San Jose to see what's...
Google Uses Click Data to Influence SEO Rankings
How Google's systems treat click data, and the straight facts about what it means for SEO and rankings. https://t.co/3hJjjfp9A9 via @martinibuster, @sejournal
Include Sustainability Early: Decisions Shape Strategic Impact
Sustainability has the most leverage before anything gets built. Christopher Wellise (@cwellise), VP of Sustainability at @Equinix, makes a clear case: if you are not in the room before the first architectural diagram is drawn, you are already too late. Where...
NYT Digital Ads Surge 25% After Video Pivot
Yes, and to add a bit more context: The New York Times Company saw its digital advertising revenue stall -- even decline, as it did by nearly 4% in Q4 2023 -- until it strategically embraced video. In Q4 2025, its...

AI Becomes Infrastructure, Reshaping SaaS Adoption Dynamics
Marcelo Lima on the gen AI threat to SaaS: - Tailwind for the early adopters with switching costs - Mission critical software is altogether different - AI tools work more like an infrastructure layer - Software engineers today work more intensely, i.e. the market...

AI Becomes Healthcare’s Operating Layer, EHR Becomes Plumbing
This is bigger than 𝗰𝗼𝗽𝗶𝗹𝗼𝘁𝘀. 🚀 OpenAI, Anthropic, and Google are racing to become the 𝗼𝗽𝗲𝗿𝗮𝘁𝗶𝗻𝗴 𝗹𝗮𝘆𝗲𝗿 above healthcare’s fragmented mess. 🏥 Once AI becomes the interface, the EHR stops being the 𝗱𝗲𝘀𝘁𝗶𝗻𝗮𝘁𝗶𝗼𝗻. 📍 It becomes the 𝗽𝗹𝘂𝗺𝗯𝗶𝗻𝗴. 💧
FAA Targets 2026 Approvals, Fleet Upgrade by 2028
Timeline on issue per OIG: "In our latest update from FAA, it stated the engine-level approval is expected in the 2nd quarter of 2026 and the airplane-level approval is expected in 3rd quarter of 2026. Further, once Boeing publishes its...

AI Excels at Data, Not Human Coaching Insight
Will AI replace sports practitioners? When software can automatically generate fuelling plans, detect performance trends in seconds, it becomes natural to wonder where the human expert fits in. In this blog we discuss what AI does exceptionally well, and what...
Interviewing T1 Energy CEO on Texas Renewable Boom
Looking forward to this event. I'll be interviewing T1 Energy CEO Daniel Barcelo about the Texas renewables boom. #energy #solar
Karpathy's Free 2‑Hour Deep Dive Explains ChatGPT
I still can’t believe @karpathy released this 2-hour deep dive on how ChatGPT actually works ... for FREE 🤯 https://t.co/tLXPVBe1Ol
AI Advisor Beats $5k Advisors, Disrupts Wealth Management
Your financial advisor charges $5,000/year and doesn't know what you had for breakfast. Astor connects to your actual brokerage, reads your real portfolio, and texts you AI-driven advice in real time. $200M in assets connected in under 2 months. The wealth management industry...
NanoClaw 2 Adds Agent Communication, Human Approvals, 15 Platforms
Introducing @NanoClaw 2 with cofounder @Gavriel_Cohen. v2 brings agent-to-agent communication, human-in-the-loop-approvals, support for 15 messaging platforms, and more. https://t.co/B6RmKJ7rcT
U.S. Pioneered Solar, Policy Lapses Ceded Lead to China
Just to set the history right. USA went for solar before China did. Jimmy Carter installed them on the White House in 1979. USA led the technological and commercial landscape until the mid 80s but because of lack or state...
Anthropic Cuts Claude Code Instead of Enforcing Quotas
why remove a product line (claude code) instead of just enforcing the quota? anthropic is actively trying to make it difficult to use the tokens I ALREADY PAY FOR
AI Now Generates 75% of YC Startup Code
Each Y Combinator batch I ask the startups what percent of their code is written by AI. It passed 75% at least a year ago, maybe two.
Gene Therapy Cures Specific Deafness—A Modern Miracle
Another modern miracle: Gene therapy cures a form of deafness. Harvard to USA: You're welcome. https://t.co/mfEzVMGugp
AI Could End Endless Rewatching of Same Movies
If I'm going to be cautiously optimistic about AI in creative fields, maybe, just maybe, it can free us from the hell of having to watch the same movies over and over.