Consistent AI Bull: From Early Bets to 2026 Momentum
me/air street 2014: begin investing in ai startups 2016: what wall st misses on nvidia 2017: why go long on ai 2021: the ai revolution is just starting 2024: ai is not the dot com bubble 2025: a monumental 12 months in ai 2026: lesgooooo ref: https://t.co/XGw95trGIq
Health Sites Tumble as AI Overviews Erode Rankings
Really wild to see authoritative health publishers who have dominated in SEO for many years get hit so hard by this last core update, across various media networks Wondering if there is some cycle where content is now being answered by...
Day 8 Challenge: Guess the Phrase in Fewest Characters
day #8 of the prompting game how many characters will it take you to get the AI to guess today's phrase? play at https://t.co/jmmguoWeQG https://t.co/jlL6jelBe9
Teach AI to Unlock New Possibilities, Not Just Speed
I gave my Ops leader Lewis one prompt: forget faster. What's possible now that wasn't before? He said hold my Monster Energy and did the wildest thing. A lot of Ops people might have tried to keep this all to...
Expert M&A Advisory Guides Founders to Maximize Exit
What sets @acquiredotcom apart? Our M&A advisory. We guide you through every step of your acquisition to maximize your exit. This M&A Insights Call showcases how Rainier Nanquil leads calls and gives guidance to founders. Learn more here: https://t.co/5hGUQheGfG https://t.co/6GklAPQyK5
Python Script Merged Files for Seamless ChatGPT Input
before all these agents, i always had a python script that would traverse all the folders and files to concat into a single file so i could copy/paste easily into chatgpt
Adam Wills Joins to Explore Quantum Error Correction
What a pleasure to have @adam_wills1 visiting us for this week to discuss notions of #quantumerrorcorrection. https://t.co/07pCKcT4pv
Consumers Test Financial Services Before Full Commitment
Financial relationships take time. Consumers kick the tires before committing fully, just like buying a used car. Digital players understand this patience. https://t.co/2BdOuNRPaG
Fed Refuses Transparency on Synapse Oversight, Cites Confidentiality
Fed continues stonewalling all requests for transparency regarding its oversight of Synapse, arguing it is confidential supervisory information: https://t.co/VQcPyPqkNw
Blue Origin Ops Director Steps In as Passenger Falls Ill
Blue Origin's own Laura Stiles, Dir of New Shepard Launch Operations, will get a chance to fly on New Shepard herself tomorrow bc one of the scheduled passengers (Andrew Yaffe) is ill and she'll take that seat.
Simple 10‑Slide Deck Drove $13M ARR in 26 Months
I bootstrapped my first startup to $13m ARR in 26 months with only one sales rep doing OUTBOUND sales. The crazy part? Diana Ross did the same demo over 2,000 times using the same 10-slide deck. 👇 I just re-discovered...
Build a ChatGPT App in 30 Minutes, Reach 800M Users
You can build a ChatGPT app in 30 minutes that reaches 800 million users. This is the kind of distribution opportunity that comes around once or twice a decade—like the App Store in 2008 or SEO in the early 2000s....
AI Powers the Next Evolution of Data Stacks
After a decade of success, the modern data stack has entered consolidation. What comes next? The postmodern data stack is AI. The modern data stack created more than $100 billion in market cap with a simple promise : move the data via...
Engineering for Real-World Impact, Not Flashy Robots
Being a MechE at Sunday isn’t about building flashy dancing robots. It’s about deep system thinking and the urgency to make robots genuinely useful for millions of homes.
Prioritize Mindset and Self‑Care Over Bigger, Louder Goals
January always gives me just enough quiet to think, right before the calendar fills up and momentum takes over. This year, I’ve been asking myself one simple question: What do I want to do differently in 2026? Not bigger. Not...
AI Shadow Negotiators Accelerate Deal-Making
Using AI to prepare for a negotiation. For our free newsletter this week, we discuss AI shadow negotiators: invisible agents shaping human deals. @IrenaCronin and I write this newsletter every week. AI shadow negotiators are AI tools that quietly help people negotiate by...
Pauli Twirling + Probabilistic Cancellation Boost NISQ Fidelity
Back in 2023, I gave a series of lectures at the Boulder Summer School on then-recent techniques we developed for error mitigation in NISQ devices, specifically how to combine Pauli twirling with probabilistic error cancellation to improve fidelity in noisy...
PAI Boosts Claude Code Efficiency by 50% – Free Workshop
PAI is a super power. @DanielMiessler created features on top of Claude Code that increase its efficacy by 50%... and that's a lot based on how awesome Claude Code is. Incoming FREE workshop of PAI and other tools I'm using to...
Data Science Success Requires Six Integrated Dimensions
📊 The 6 Dimensions of Data Science — a practical lens, not a buzzword map This framework is useful because it answers all the real questions leaders should ask: 1️⃣ Goals — Why Data Science? Insights, prediction, automation, optimization, and...
Empower Teams with AI Fluency for Future Success
We're teaching everyone on the team to build AI workflows. Not to replace them. To unleash them. Most companies pick one of two paths: automate people out of jobs, or ignore AI and fall behind. We're doing neither. Customer experience....
Visible, Honest CEOs Accelerate Startup Growth
What I see CEOs at struggling start-ups do: - Go dark - Hide - Lash out - Tweet about lots of things non-work - Invest time on tiny expenses - Argue internally What should do: - Be Present - Be Honest - Be the Rock - Be Realistic/Optimistic You just plain grow...
RFK Jr. Seeks Overhaul of Vaccine Compensation Panel
RFK Jr. is moving to remake a panel involved in that compensating people who are injured by vaccines. It could have big consequences. By @ChelseaCirruzzo. https://t.co/S98hMN6Vd0
Longevity Biotech Shifts Focus to Root Causes
Longevity biotech now targets root causes rather than single diseases. This is a paradigm shift in medicine
AI Becomes Marketing Infrastructure; Power and Ethics Prevail
2025 will be remembered as the year AI stopped feeling “emerging” and started feeling like infrastructure. It quietly seeped into every layer of marketing—creative, media, analytics, and even how leaders frame strategy and risk. At the same time, the social...
Mapping Tumor‑Immune Spatial Interactions in Solid Cancers
Decoding the spatial dynamics of tumor and immune cell interactions in solid cancers https://t.co/AHgt77Ee2t https://t.co/1Xxkt45JlD
Reset SaaS Conversion Benchmarks: Contribute Real Data
AI is messing with SaaS Conversion Benchmarks across the board. It’s time to reset expectations. We’re teaming up with Kyle Poyar @ Growth Unhinged and ChartMogul to build the 2026 SaaS Conversion Benchmarks. There’s too much anecdotal advice, and not...
Data Ownership Walls Threaten AI Startup Survival
A wave of AI startups is about to die - and most of them don't see it coming. not because their product is bad. because they built on someone else's data, and the landlords are changing the locks. For a...
Small Moments Define Trust, Performance, and Culture
The moments that change everything at work are rarely the big ones. They’re the passing comments, the tone in a reply, even the way a leader shows up in the in-between. These “insignificant” moments quietly shape trust, performance, and culture...
Limited Choices Boost Response; Three Is the Sweet Spot
The most overlooked way to increase response? Give someone a choice. When you have a choice, you’re in control. And all humans crave control. We want to feel some agency. We don’t like to feel forced… Or backed into a...
Fintech Secures 11% Venture Funding, Second to AI
Fintech is quietly back in the spotlight. It now captures 11% of global venture funding, second only to AI. Rounds are getting larger, and investors are focusing less on hype and more on business models that actually scale. The signal matters. As...
Use Repetition to Slash Bioinformatics Analysis Time
Are you ready to level up your bioinformatics skills? Let’s talk about repetition—a key concept that can save you hours in real-world data analysis. https://t.co/2Dtc9hz46e
Free 90‑Minute Sales Kickoff to Transform Your 2026 Performance
Tomorrow I'm doing something I've never done before: Putting on a FREE, 90 Minute Sales Kickoff (SKO) for ANYONE that wants to dramatically improve their sales skills and mindset for 2026 - B2B, B2C, sales leaders, soloists, this is for...
Shared Decision Making Misused to Question Vaccine Science
Shared clinical decision making was devised to help patients & their doctors make choices when the answer isn't clear cut. People who devised the approach fear it's being hijacked to undermine decades of study supporting #vaccines, @EricBoodman writes. https://t.co/JMmaHTI7eg
Kennedy's Push Could Drive Vaccine Makers Out
Vaccine proponents worry that Kennedy will drive manufacturers from the US market by adding autism to the vaccine injury compensation program & unleashing a flood of litigation. The path to that change is through a committee he's currently "acip-ing." (clearing...
EQ Beats IQ: Human Touch Wins in AI Era
With AI, what’s more important: EQ (Emotional Quotient) or IQ (Intelligence Quotient)? #sponsored Gary Nugent , CEO of Informa TechTarget says brands who master the “right-brain” EQ elements of the buying journey will win in the age of AI. Full...
Intronic Reads in 10x 3′ UMI Data Explained
You’re analyzing 10x Genomics single-cell RNA-seq and notice lots of intronic reads. Wait—wasn’t this a 3′ UMI-based assay for mature mRNA? Let’s unpack why introns show up—and why they matter. 🧵 https://t.co/cDeb8dfLAS
Personal Brand Issues Are Just Messaging and Offer Gaps
Most "personal brand" problems are messaging or offer problems in disguise Sell something people want Explain it so they know why they should want it Creating unignorable content becomes much easier
Align AI Product Messaging with 2026 Enterprise Adoption Trends
For all you marketers trying to generate demand for AI products or features, this one's for you: It's all about helping you understand the top trends and pains in AI Adoption in the Enterprise in 2026 so you can align...
Founders’ Top 3 Costly ICP Mistakes Revealed
After working on 500+ Ideal Customer Profiles, I’ve identified the top 3 mistakes most Founders make– and they’re costly. In fact, many Founders inside my Unstoppable Go-To-Market program joined because their ICP wasn’t delivering growth or results. The three most...
CRVS Shows Promising AD Efficacy, Needs Tissue Validation
$CRVS +57% premarket on AD Cohort-4: randomized PBO-controlled signal (EASI-75 75%, mean EASI −72% vs −40% PBO; p=0.035) with clean safety, real but fragile (n=12 vs 12; 10 PBO-evaluable). 📝No skin-biopsy disclosed. While exiting progress serum PD != tissue reversal....
Free Tool Detects Keyword Cannibalization Instantly
A new, free and easy to use keyword cannibalization analyzer is here: CanniWizard by @jbobbink 🙌🔥 You use need to: * Connect your Google Search Console properties * It will automatically find cannibalization problems where multiple pages compete for the...
Revamp Seat Pricing: AI, Roles, Tiers, Credits
You don't need to stop pricing per seat in the age of AI. But you (probably) need to make seat-based pricing work harder. Seven routes to consider: 1. Seats can be used by people OR AI agents. If AI agents...
Ship, Get Feedback, Iterate—Skip the Endless Steps
50 steps won’t make you good at AI. Shipping → feedback → iteration will. Stop collecting steps. Start closing value loops. https://t.co/7ZfPKlVood
Albania's AI Minister Signals New Era of Governance
Albania announced the world’s first AI minister, creating global headlines. In this video, I break down what really happened, why language matters in public policy, and what responsible AI governance should look like. 🧠🌍 #AI #Government #Ethics #DigitalPolicy #ArtificialIntelligence
AI Aids Thinking, Not Decision-Making Responsibility
People keep asking whether ChatGPT can make decisions for them. Here’s the short answer: no - and that’s exactly why it’s useful. A decision isn’t a paragraph of text. It’s a commitment that allocates resources, creates consequences, and leaves someone...
Key AI-Driven E‑Commerce Signals Marketers Prioritize Now
Here's what e-commerce signals marketers think will impact if AI showcases your product over the competitors. These signals will adjust over time as commerce through AI becomes more popular... but here's what 100 marketers think is important today. https://t.co/DzjF8lqF19
CRVS Shows Promise Yet Remains Early, Uncertain
Lots of haters on $CRVS and yes the way they’ve disclosed data over time is a little iffy but 🤷🏻♂️. Active drug. New data looks solid. They ought to be able to fund the P2. They’ve got...
Out‑of‑the‑Money ABVX Calls Hint at Genuine Deal
I know (and understand why) there’s a lot of speculation around the credibility of the La Lettre articles on $ABVX M&A. I have no idea whether the reporting is legit. Could it be made up BS as part of some...
Corvus Pill Yields 75% EASI‑75 Response in Eczema Trial
$CRVS Corvus pill shows promise in early-stage eczema trial 75% of participants treated with soquelitinib achieved EASI 75 after 8 weeks compared to 20% of placebo participants offered a placebo. https://t.co/XlOmX0GUZf
Understanding ORR and RECIST v1.1 Response Metrics
Investors will often see ORR quoted or displayed for oncology clinical trial results for solid tumors Here's what the CRs/PRs/SDs mean at a high level These are assessed on scans I'm using RECIST v1.1 definitions #learnbiotechinvesting #biotech #investing #BiotechPrometheus https://t.co/1YAoHGXujW