
NR & NMN Boost Blood NAD+ via Gut Microbiome
The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans “Collectively, the clinical data combined with the ex vivo human microbiota and human whole-blood experiments led us to propose a human model where NR and NMN are retained and further metabolized in the gut by the microbiome giving rise to NA, which then boosts NAD+ levels in whole blood. In contrast, Nam is directly absorbed and metabolized, transiently increasing NAD+ levels…” https://t.co/o0U9x1ellJ
CFOs Must Build AI Governance, Not Just Prompts
🚨 ANNOUNCEMENT 🚨 This month's Secret CFO Playbook will be the No BS Guide to AI for CFOs. Tomorrow I kick off a 4-part newsletter series getting deep into the CFO-grade issues in rolling out AI for finance. It's time to move...

Cast.app Narrows MCP Role for Select Agents
Why @CastDotApp Is Narrowing MCP’s Role for Select Agent Use Cases https://t.co/pUsztCYAIe #MCP #AI #data #customerexperience https://t.co/u2NoyBj7FB
AI Writing Shortcuts Can Weaken Your Brain—Stay Active
"When you ask ChatGPT to draft your email or memo, you are not just saving time. You are skipping a cognitive workout. And like any muscle left idle on the couch, the brain responds accordingly: it atrophies." https://t.co/5YPJqYodJn < keep...
Republicans Cling to Fossil Preference Despite Renewable Surge
Propaganda has brainwashed some of the public to think fossils are good and wind/solar are bad, but fortunately, reality and physics win, as new wind and solar are dominating in the U.S. and worldwide. "A year into the second Trump administration,...
AI Shifts From CIO to CEO, Board Strategy
Brian Bryson, Principal Analyst, Technology & Business at MIT Technology Review (@techreview) on the current state of autonomous business models and how AI is no longer just a CIO conversation — it’s a CEO, board, and operating model conversation. https://t.co/4sW1VVoeYl
FlexGen Expands Portfolio by Acquiring Clean Energy Services
FlexGen moves to expand offerings with acquisition of Clean Energy Services #energysky -- via pv magazine usa: https://t.co/gH2wMVbd2S
LLM Psychosis Linked to Credulity, Not Intelligence
This doesn't match my experience at all. The people I know with LLM psychosis index high on credulousness rather than intelligence.

SoFi's Fintech Façade Hides Risky Unsecured Loan Engine
$SOFI's "fintech" mask hides a massive unsecured lending operation - Bank in disguise: lending ~90% of profits, NII >60% - Growth driven by risky unsecured loans in a saturated market - Aggressive accounting inflates earnings - Re-rate to bank multiples => 60%+ downside https://t.co/ZZ8DRGoMRM

Galaxy Weather Gets Sleek UI Overhaul, Compact Moon Tracker
Your Galaxy's Weather app just got a facelift Version 1.7.30.8 tweaks the UI across several cards, including a more compact moon phase tracker. ✅ Details/Screenshots - https://t.co/baoMYWOMcx https://t.co/69bX7zuPui

Cut AI Costs 58% With Smart Model Routing
2) It stops wasting your money: Most agents use expensive models for everything. ClawXRouter changes that. It acts like a smart traffic cop, it figures out how hard your task is and sends it to the cheapest model capable of handling it. The...

EdgeClaw’s ClawXMemory Summarizes Chats for Persistent Recall
1) It actually remembers you: Instead of just dumping your whole chat history back into the model (which gets messy and expensive), EdgeClaw uses ClawXMemory. Think of it as a 3D tree: it automatically summarizes your chats, organizes them into long-term project...

Leaked Claude Code Sparks Open-Source Memory System EdgeClaw 2.0
Claude Code’s source code leaked recently. It was a massive "open book" moment that accidentally revealed Anthropic’s secret "memory" system. A group of researchers saw exactly how it worked and immediately rebuilt it for the open-source community. EdgeClaw 2.0 is now live. Here...
Claude Excels at Overnight Batch Tasks, Struggles with Visual Reasoning
Claude computer use review: Bad at human-level visual reasoning when tested in PPT, like “pick which slide template works best for a slide about the 4 ways to schedule agent tasks and make the slide” Too slow for daytime quick support. Pretty epic...
AI-Generated Code Delivers 25x Productivity, QA Becomes Bottleneck
This week in our SaaS CEO masterminds, one stat blew my mind Multiple companies reported 50-100% of their production code is now AI-generated. One team rebuilt an entire platform in 2 months with 4 people...a project previously scoped at 1...
Veteran Tech Leaders Reveal Unexpected AI Development Strategies
How do experienced tech people like @adrianco think about using AI to build software? The answer may (or may not) surprise you. I like this series of thoughts and advice ... https://t.co/xi0Xips0NO
Build Unique Distribution Channels Competitors Can’t Copy
Your competitors are creating content. Your competitors are buying ads. Your competitors are hoping for attention. You should be building distribution channels they can’t replicate.

Good AI Diagnoses, Bad Chat Interface Worsens Outcomes
This new Nature paper (using old models) illustrates the point of my latest Substack post on AI interfaces. AI did a good job diagnosing medical issues, but when users had to interact with chatbots the interface led to confusion &...
Claude, ChatGPT Reject Authoritarian Prompts 85%, Grok 24%
Claude and ChatGPT refuse to help authoritarian requests 85% of the time. Grok refuses 24% of the time. On brand.
Electrospray Cooling Boosts Solar Panel Efficiency, Saves Water
Electrospray cooling can boost PV panel performance with minimal water use #energysky -- via pv magazine global: https://t.co/tFbOoSFCLn

People Dismiss Real Data, Preferring Comforting Lies
I'm the one guy who posts a public-facing revenue dashboard…and people in the comments still don't believe it was real. Them: "If that's real, you should sell your company." I think that's just something about people. When they see...

Keras Kinetic: Decorator‑Based TPU/GPU Jobs Made Simple
Perhaps the craziest thing that was introduced on the Keras community call today: Keras Kinetic, a new library that lets you run jobs on cloud TPU/GPU via a simple decorator -- like Modal but with TPU support. When you call a...
Apex Model Now Accessible via API
The #1 question I got last week was "Will @Fin_ai's Apex model be available as an API" The answer, now, is yes. Good read below as to why...
10 Organic Inquiries in Two Weeks: Client Wins
Friday Flex- 10 organic website inquiries in the last two weeks for one of my clients. *shines nails on shirt*
Wearables Distinguish Real Fatigue From Cat‑like Laziness
Wearables (can) help with that eternal question... "I feel kinda tired today. Am I really tired, or am I just being a 🐱?" That question is a very stressful question for athletes. It can rattle around in your head for days. And...

Eight LLM Categories Power Next‑gen AI Agents
8 Types of #LLMs for Next Generation #AIAgents by @PythonPr #GenAI #AI #ArtificialIntelligence #MachineLearning #ML https://t.co/DjaILxp2Cp
AI-Driven Lambda Troubleshooting Auto‑detects Missing VPC Security Group
This past week I wrote a lambda troubleshooter using the concept on this blog post where it deterministically queries a bunch of logs and sends them to an ai 🤖 agent for analysis and troubleshooting. I had to redact...

AI Medical Tools Need Evidence, Not RCTs, to Trust
How can we trust CDS AI like OpenEvidence, DoximityGPT, etc if no one's done studies showing their use improves patient outcomes? While I understand the intent, I think it's ultimately a misguided question. Anytime a new medical textbook comes out, should...
Commoditized AI Benefits Users and the World
In the absence of some sort of network effect or virtuous cycle, AI models will be commoditized. That's great news for users of AI and for the world.
Analysts Unleashed: Deep Dive Into Enterprise Software
Skip to content Analysts Gone Wild | Analyzing Enterprise Software Stories | Episode 54 https://t.co/JuYUyAvrW0
Story-Driven Welcome Emails Beat Discount Offers
I've audited 50+ ecom email flows. Here's the pattern: Welcome series with a 30% discount got low engagement. Welcome series that told the founder's story and solved a problem got 3x the open rate and 2x the clicks. Your discount...

Outdated Claim Debunked; Poster Sells Security Solution
Quick debunk by @alexoterov @mosesfinlay The post is bullshit and based on January 2024 models Also the guy who posted it is selling his own security solution DEBUNKED https://t.co/vRfA4IHiRA
AI Foundation Models Will Let LLMs Reason About Atoms
Fun conversation on @NoPriorsPod w @LiamFedus on AI Foundation Model for Atoms from @periodiclabs -Foundation models that understand atoms -LLMs as reasoning engines -Timing to displace AI researchers Liam prior was VP Post Training at OpenAI, now CEO Periodic https://t.co/jmiv5uQt8U
AI Tools Often Slow Developers, Study Finds
I think about this study frequently (quoting from my report on "GenAI & Productivity" https://t.co/kEx5Z4BJH7): In results released in July, non-profit Model Evaluation & Threat Research (METR) had a troubling finding. Sixteen experienced developers participated in the study. They were...
Only Humanity Can Balance AI’s Unchecked Power
Close your eyes for a second and imagine a balancing scale. On one side is the problem — trillions of dollars of investment going into making uncontrollable inscrutable AI, the race for geopolitical power, and forever dominance. Then, on the other...

AI Strategy Undermines Top Talent's Job Performance
#AI Strategy Is Quietly Making The Best People Worse At Their Jobs by Sarah Choudhary @Forbes Learn more: https://t.co/Jt3TNejz8e #ArtificialIntelligence #MachineLearning #ML https://t.co/7WqAgvyXL5
Gemma 4 Dominates Hacker News, Highlights Apache 2 License
Sheesh, Gemma 4 stayed at the top of Hacker News for most of the day yesterday. A lot of the positive vibes were around the Apache 2 license. More on that, from @Sam_Witteveen: https://t.co/0GXUntxySL Also, @matthewmccull explains the Android angle: https://t.co/pG5RBKO3aP

Humans Return Beyond LEO After 50 Years
Getting a ringside seat to space history - after over half a century humans venture out beyond LEO again #Artemis #NASA #spaceflight #ArtemisII https://t.co/RMT4s1iZSC https://t.co/7NGliTWrD1
Nation's Largest Urban Battery Deploys Near San Francisco
Nation's largest urban battery to take center stage near San Francisco #energysky -- via Canary Media: https://t.co/fv1RqbWPt2

Revolut's Tiny Fine Masks Looming AML Supervision Costs
Revolut's 2025 profit: $2.3 billion. The Lithuanian AML fine: €3.5 million. Trivial relative to profit. But it may have just put Revolut at the top of AMLA's direct supervision list starting 2028. AMLA supervision isn't a fine. It's a permanent structural overhead. That changes...

Non‑Tech Professionals Build Custom AI Agents Fast
I just helped hundreds of business professionals build their first AI agents in my AI Agent Mastermind. Here are five built by people who had never opened a terminal before this week: 1️⃣ A personalized morning brief. She took my original...

Artemis II Captures Earth’s Auroras and Zodiacal Light
Breathtaking view of Earth taken by Artemis II commander Reid Wiseman after the TLI burn yesterday. The NASA post (link below) explains the two auroras and the zodiacal light in the image. https://t.co/jSToocbGT1 https://t.co/7lbb8pErhF
Zipline Launches Autonomous Charging Stations for Drone Fleet
Zipline Unveils #Autonomous Charging Stations for Its #Drone Delivery Fleet by @tweetciiiim #EmergingTech #Technology #Innovation https://t.co/qGhjC53ysu
Ridiculous NASA Budget Complicates Isaacman's Mission, Congress Steps In
It's hard to get too exercised about the ridiculous White House budget for NASA, because Congress will address a lot of its issues. But this will make Isaacman's job a lot more difficult than it need be.
Automation Protects Human Judgment, Not Replaces It
One of the sharpest thoughts I’ve heard about AI did not come from a founder, consultant, or conference speaker. It came from a Ryanair pilot I train BJJ with. He said that in aviation, automation is not there to replace human...
AI-Generated LinkedIn Comments Turn Users Off
I’ll see a post on LinkedIn I like and want to engage with and the I read all the AI generated comments from “experts” and I’m turned off and don’t comment. Anyone else do this? Why are yall yang bots...

Memory Supply Chain Faces Growing Constraints, Market Unaware
The memory point is not the only interesting comment here, but we have had a range of supply chain chats on memory, and I don't think the market fully grasps what's coming. We are stacking constraints at this point. This...
Anthropic CCO Warns of Monthly Token Bill Shock
We caught up this week with Anthropic chief commercial officer @realpaulsmith who was basically saying “we send these big companies bills every month for their tokens” and the sticker shock seems real

China's Energy Storage Boom: Watch Inventory Data
China's energy storage market is booming. One Chinese analyst thinks you should look at the inventory data . Read more and sign up to my newsletter here: https://t.co/ck3zk49kBX https://t.co/sA0TPeUWMc
Planetary Society Warns FY2027 NASA Science Cuts
Statement from The Planetary Society about the new FY2027 proposed budget cuts to NASA's science programs: https://t.co/qDYyJ2dGOB