Know What's Happening in Healthcare
Know What's Happening in Healthcare
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
A recent study in the Journal of the American Heart Association found that a five‑minute high‑resistance inspiratory muscle strength training (IMST) protocol can lower systolic blood pressure by about nine points in adults aged 50 to 79. The intervention, performed six days a week for six weeks, also boosted vascular endothelial function by 45% and increased nitric‑oxide levels, markers linked to arterial health. Benefits persisted for at least six weeks after participants stopped the breathing exercises. Researchers claim IMST’s efficacy rivals that of conventional aerobic exercise and antihypertensive medication.
The federal and Manitoba governments have committed $300,000 over two years to extend the Manitoba Farmer Wellness Program. At the 2026 Commodity Classic, agricultural leaders used the funding announcement to demand expanded mental‑health resources for farmers nationwide.
Doula services, once a niche luxury for affluent families, are now being offered through employer benefits and Medicaid programs, raising the proportion of births with doula support from about 2% a decade ago to roughly 10% today. The shift promises...
Legal psilocybin retreats in Oregon have documented therapeutic benefits for dozens of participants, including 70‑year‑old Martha Stem, who said the experience helped her confront decades of trauma. The trend underscores a growing convergence of regulated psychedelics and meditation as an...
A research team led by Liu Guanghui at the Chinese Academy of Sciences released a comprehensive map of inflammatory aging across multiple organs and introduced two anti‑aging strategies—a betaine‑based small‑molecule and engineered FOXO3‑edited stem cells. The work was named one...
A Beijing hospital has given the first prescription of Libevitug, the inaugural monoclonal antibody targeting hepatitis D. Developed by Tsinghua University researchers and Huahui Health, the drug received conditional approval in January 2026 and could transform care for an estimated...
Boston Scientific announced that its WATCHMAN FLX left atrial appendage closure device met all primary and secondary safety and efficacy endpoints in the CHAMPION-AF trial, delivering a 45% relative reduction in non‑procedural bleeding versus NOACs while matching stroke‑prevention efficacy. The...
Insurers withdrew Medicare Advantage plans from thousands of counties, forcing nearly 3 million seniors to leave the private program and seek alternatives. The churn, the highest on record, hits rural states hardest and raises questions about the sustainability of the privatized...
The NNPC/Seplat joint venture’s “Eye Can See” corporate social investment program in Imo State has delivered 23,447 free eye screenings, performed 797 cataract surgeries, and distributed over 13,525 glasses since its 2017 launch. The three‑day outreach in Owerri, held March...
Researchers led by Prof. Heidi Abrahamse at the University of Johannesburg have unveiled a liposome‑based nanotechnology platform that upgrades photodynamic therapy (PDT). The platform protects photosensitizers in the bloodstream, targets tumors more precisely and releases the drug only where light...
Eli Lilly reported that its open‑label Phase 3b TOGETHER‑PsA trial met its primary and all key secondary endpoints, demonstrating that adding Zepbound (tirzepatide) to Taltz (ixekizumab) significantly reduced psoriatic arthritis activity and body weight versus Taltz alone. The data, presented...
Kaiser Permanente reported a $9.3 billion profit on $127 billion revenue, while its cash reserves swelled to $73 billion. The nonprofit settled a $556 million Medicare fraud case and a $30 million mental‑health lawsuit, both without admitting wrongdoing. Rising premiums, staff shortages and a 30,000‑person...
A recent blog post dubs the SARS‑CoV‑2 sub‑lineage BA.3.2 the “Cicada” variant, drawing on the insect’s symbolism of rebirth. The author suggests the strain is resurfacing ahead of the CDC’s fall nRNA COVID‑19 booster push, but provides no epidemiological data...
"Doctors, every patient checks reviews before visiting. Here’s how one of my clients, A Doctor grew from 12 reviews (4.8 stars) to 712, 5-star reviews—and tripled their patient footfall within 3 months. These are the exact same hacks I’ve shared with...
Robots are starting to enter one of the most sensitive environments we have. Healthcare. Unitree’s systems being used as caregivers and assistants show how robotics is moving beyond factories into real-world human settings. The value is clear: Supporting staff with repetitive tasks Assisting with logistics...
Weekly reads highlight several frontier biotech developments. The Gattaca Stack, a new database, tracks firms working on embryo models and artificial‑womb technologies. R3 Bio’s stem‑cell “organ sacks” aim to replace animal testing and could evolve into human organ bags, while...
Concur that COVID was very likely zoonotic in origin. That's always been the most likely scenario, and the evidence has just grown stronger. (See below.) From a policy standpoint, I don't think it matters much. 1. Some past pandemics have originated...
High‑quality scalers curette sets and extracting forceps are essential for modern dental practice. These instruments provide sharp, ergonomic designs that improve plaque removal, precise tooth extractions, and reduce hand fatigue. Their durable stainless‑steel construction extends lifespan, delivering cost savings for...
Recent dust storms in El Paso have triggered a surge in respiratory illnesses, from asthma attacks to severe Valley fever infections. A University of California study found hospitalizations jump fivefold after dust events, while Texas does not require statewide reporting of...
The synthetic opioid market: Why cartel arrests do not stop the crisis http://dlvr.it/TRlsbG Conditions #PainManagement
Over HALF of all spine surgeries performed in the US are unnecessary. We know this because spine surgeons said so. When patients got a second opinion, 60% were told the surgery they were recommended didn’t need to happen. The best non-surgical treatment for...
Post‑COVID America faces a sustained surge in mental‑health demand, with anxiety, depression and chronic stress cases outpacing pre‑2020 levels. Simultaneously, therapist supply lags, leaving many regions designated as mental‑health professional shortage areas. Clinicians report packed schedules, waiting lists, and increasingly...
Andhra Pradesh chief minister Y.S. Jagan Mohan Reddy inaugurated the Tholi Mudda breakfast scheme, a state‑run program that will deliver a daily nutritious meal to children enrolled in the anganwadi system. The initiative targets roughly 1.5 million beneficiaries and is positioned...
Four Seasons Health Care, founded by Robert Kilgour in 1989, grew to 43 homes before being sold to a private‑equity consortium in 1999. The deal launched a wave of PE ownership that has turned elderly residents into cash‑generating assets, prompting...
Supply‑chain analysts say the United Kingdom is only weeks away from shortages of essential medicines, from painkillers to cancer therapies, if the Iran war drags on. Disruptions to Gulf air routes and the Strait of Hormuz have forced firms onto...
Trinity Capital Inc. has pledged $50 million in growth capital to Arkansas‑based Sage Health. The funding will accelerate the provider’s senior‑focused care platform and geographic expansion into medically underserved regions, underscoring the role of investment banks in structuring health‑care growth deals.
A UC Health‑wide hypertension algorithm was embedded in electronic health records for roughly 90,000 patients, raising the proportion of controlled blood pressure from 68.5% to nearly 74% by mid‑2025. The stepwise, clinician‑guided tool, called the UC Way Hypertension Medication Algorithm,...
The British Heart Foundation warned that popular gut‑friendly foods such as kimchi, sauerkraut, kombucha and fruit smoothies can pose hidden cardiovascular risks due to added salt, sugar, and low fiber. Cardiology dietitian Michelle Routhenstein clarified that while probiotic strains may...
Insurance companies should sue doctors offices and hospitals that bill them for a “doctor visit” when the patient only sees a Nurse Practitioner. Personally I’m tired of the Nurse Practitioner scam. And it is a scam. They pay them far less...
Researchers at the University of Pennsylvania and collaborators have developed a preclinical gene therapy that selectively silences pain‑processing circuits in the brain, mimicking morphine’s analgesic effect without activating reward pathways. Using an AI‑driven system to map morphine‑responsive neurons in mice,...
A population‑based analysis of U.S. death certificates from 2020‑2022 examined Alzheimer’s disease mortality across 443 occupations. Taxi drivers (1.03% of deaths) and ambulance drivers (0.91%) showed the lowest adjusted proportions of Alzheimer‑related deaths, well below the overall adjusted rate of...
Grow Therapy announced a $150 million Series D round led by TCV and Goldman Sachs Alternatives. The capital will be used to deepen partnerships with employers and health systems, accelerating the company’s push to embed mental‑health services in workplace and clinical...
The National Institute of Mental Health and Neurosciences (NIMHANS) released a study indicating a steep rise in parental concern over children's screen time across India. The findings highlight growing tension between the perceived educational benefits of digital media and emerging...
Eli Lilly’s experimental injectable retatrutide has reported substantial weight‑loss outcomes in a 2023 trial, positioning it as a potential challenger to existing GLP‑1 drugs. The triple‑agonist targets three metabolic receptors, and large Phase 3 studies are now under way, drawing attention...
Enterprise AI firms are deploying uncertainty‑aware diagnostic platforms, a shift underscored by GitLab founder Sid Sijbrandij’s self‑built health data system. The move promises more trustworthy AI‑driven decisions and could reshape regulatory expectations for medical AI.
Chinese AI companies XtalPi and Blacklake have moved from loss‑making research to sustainable profitability by targeting specialized data‑driven markets. XtalPi reported a 134.6 million‑yuan ($19.5 million) profit in 2025, while Blacklake achieved its first profit in late 2024, underscoring a shift in...
Nektar Therapeutics presented Phase 2b data for its regulatory T‑cell agonist rezpegaldesleukin at the 2026 American Academy of Dermatology meeting, showing statistically significant EASI improvements in 393 atopic dermatitis patients and a 28.2% mean SALT reduction in severe alopecia areata....
The Hib vaccine protects against Haemophilus influenzae type b (Hib) bacteria, which can cause severe illnesses like meningitis, pneumonia, and epiglottitis. Th
Systemic epigenetic dysregulation as a driver of ageing and a therapeutic target 👉 “By providing mechanistic clarity on how epigenetic dysregulation drives ageing phenotypes, we aim to enable rational design of therapeutics that target the epigenetic systems that fail during ageing,...
Kardigan reported positive Phase 2 data for its antisense drug tonlamarsen in the KARDINAL trial, showing a dose‑dependent 67% reduction in plasma angiotensinogen and a mean 6.7 mmHg drop in office systolic blood pressure after 20 weeks. Both a single 90 mg dose...
Offering euthanasia to depressed people is state-sponsored murder. There is no ambiguity. It is murder.
The purpose of MAID is not to let people die with dignity. The purpose of MAID is to save the government money. They will keep pushing death on everyone they can push it on, in order to save the government...
New randomized data from the Ez‑PAVE trial in South Korea show that lowering LDL cholesterol to below 55 mg/dL in patients with established atherosclerotic cardiovascular disease reduces major cardiovascular events by 33% compared with a target of less than 70 mg/dL. The...
#ThisDayInTechHistory. March 27, 1998. The FDA approved Viagra developed by Pfizer. (Untold Story) #HealthTech #JVGpost https://t.co/GJea9vd0v9
Great thread and one addition: Increased risk of myocarditis in young boys. The demonization of parents who asked, the denials by healthcare professionals and bureaucrats, and ultimately, the admission and subsequent FDA warning proving parents worst fears correct. It will take...
Rural America faces a stark dermatology shortage, with 68% of counties lacking a specialist, leading to long travel distances and delayed skin‑cancer diagnoses. Experts at the 2026 AAD meeting highlighted that teledermatology, primary‑care provider (PCP) support, and mobile clinics are...
When I started Don't Die in 2021, we evaluated all the scientific evidence for the most powerful anti-aging therapies. Psychedelics were no where to be found. A wild turn of events that they're now front and center for us....
Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial "Here we show that microbial phenolic metabolites are driving factors for the cholesterol-lowering effect of oats.." https://t.co/Y6fmNYStmZ
Biogen announced positive Phase 2 results for litifilimab, its anti‑BDCA2 antibody targeting systemic lupus erythematosus. After 24 weeks, 14.7% of patients achieved complete clearance of skin lesions, meeting the trial’s primary endpoint. The data suggest the drug could become a...
In a randomized trial of a PCSK9 inhibitor [for LDL cholesterol lowering] vs placebo for patients with diabetes and no known heart disease, there was significant reduction of major cardiovascular events including deaths #ACC26 @JAMA_current https://t.co/mzuI79c4IN https://t.co/16Cpxf7IBx
