
FDA approves KRESLADI, first CIRM‑backed gene‑editing therapy
The FDA cleared KRESLADI, a gene‑editing treatment from Rocket Pharmaceuticals for severe leukocyte adhesion deficiency‑I in children, eliminating the need for a bone‑marrow donor. It is the first product directly funded by California’s Institute for Regenerative Medicine to receive approval.
Also developing:
By the numbers: Syneron Bio raises $150M Series B
Researchers at The Jackson Laboratory and MIT unveiled a polymer‑based microneedle skin patch that captures immune cells and inflammatory biomarkers within 15‑30 minutes. The device could transform vaccine response tracking and chronic disease monitoring by eliminating the need for blood draws.
State governments have signed contracts worth at least $45.6 million with consulting firms Deloitte, Accenture and Optum to re‑engineer eligibility systems under the One Big Beautiful Bill Act. The changes are expected to push 7.5 million people off Medicaid by 2034 and...
AstraZeneca announced that its experimental monoclonal antibody tozorakimab met primary endpoints in two late‑stage COPD trials, delivering a clinically meaningful reduction in moderate‑to‑severe flare‑ups. The data lifted the company’s shares as much as 3.8% and underpin a sales outlook of...
Eli Lilly and Hong Kong‑listed Insilico Medicine have sealed a partnership that could be worth up to $2.75 billion, including a $115 million upfront payment. The deal gives Lilly exclusive global rights to Insilico’s pre‑clinical oral candidates and taps the biotech’s generative‑AI platform....
Researchers at South Korea's KAIST have demonstrated that graphene oxide can selectively eradicate bacterial cells while leaving human cells intact. The finding points to a new class of nanomaterial‑based antibiotics that could help combat the growing threat of antimicrobial resistance.

Digital Workforce, a Helsinki‑based automation firm, serves over 200 large organizations and targets roughly $40 million in revenue this year. Its flagship Outsmart platform blends robotic process automation and AI to run entire patient‑care pathways, with a particular emphasis on healthcare...
Researchers at Washington University School of Medicine and Children’s Hospital of Philadelphia have demonstrated that volatile organic compounds (VOCs) in exhaled breath mirror gut microbiome activity. Published in Cell Metabolism, the proof‑of‑concept study showed breath profiles could differentiate children with...

GXO Logistics has been selected by NHS England to manage the supply and distribution of home testing kits for the national bowel cancer screening programme, specifically the Faecal Immunochemical Test (FIT). The logistics firm will act as a managed service...

A 2023 American Dental Association survey shows nearly 80% of adults are dissatisfied with their tooth color, yet only 15% seek professional whitening, fueling a surge in at‑home solutions. Professional treatments cost $300‑800 per session, while over‑the‑counter strips, gels, and...

Eli Lilly is urging the United Kingdom to overhaul its drug‑pricing framework, warning that persistently low prices could deter future investment and calling for outcomes‑based reimbursement models, especially for obesity therapies. At the same time, the U.S. Food and Drug Administration...

STAT’s analysis of the 50 largest publicly traded health‑care firms shows that job growth at these for‑profit giants has stalled over the past five years, even as the broader health‑care sector continues to expand the U.S. labor market. Health insurers...
Japan is experiencing a nationwide shortage of Concerta, the primary stimulant used to treat adult ADHD, as demand surges. The shortage, first noted in late 2023, persists despite Janssen Pharmaceutical’s promise of a two‑month fix, with officials now estimating several...

On Jan. 20, 2025 President Donald Trump signed an executive order that recognizes only two sexes and mandates federal agencies use the term “sex” instead of “gender.” The order abruptly removed the NIH Sex as a Biological Variable (SABV) policy webpages, unsettling...

Nearly a year after the UK outlawed single‑use disposable vapes, new data show only modest health and environmental gains. Vaping prevalence remains at 5.4 million adults, with no clear reduction in smoking‑related illnesses. Waste audits indicate a roughly 15 percent drop in...

Strength training is positioned as a modifiable lever to counter frailty, using the Rockwood Clinical Frailty Scale (CFS) to tailor exercise intensity. The article outlines a three‑level prescription matrix—supported, standard, and power—matched to CFS bands, recommending 4‑6 core movements performed...

In this episode, Mel Robbins talks with Harvard neurogastroenterologist Dr. Tricia Pasricha about the gut‑brain connection, demystifying what’s normal and abnormal when it comes to digestion, bloating, constipation, and pooping. Dr. Pasricha explains that the gut functions like a second...

A frontline health centre in Kaita, Katsina state, run by the Alliance for International Medical Action (Alima), is treating thousands of children suffering acute malnutrition as Nigeria’s hunger crisis deepens. The Red Cross warns up to 33 million Nigerians could face...

The FDA launched the AI‑powered Adverse Event Monitoring System (AEMS) on March 11, 2026, consolidating VAERS, FAERS and other databases into a single, real‑time platform. AI automates data entry and categorization, replacing quarterly updates with instant reporting. Early testing showed...
The Union Ayush Ministry launched a comprehensive "Yoga Protocol for Non‑Communicable Diseases" during Yoga Mahotsav 2026, targeting conditions that cause nearly two‑thirds of all deaths in India. Developed with WHO collaboration, the protocols blend asanas, pranayma, meditation and relaxation into...
Researchers at Sun Yat‑sen University's National Key Laboratory of Ophthalmology published a PNAS paper revealing that the protein MTFR1L maintains mitochondrial homeostasis in the heart and can slow age‑related cardiac decline. The findings open a molecular pathway for biohackers and...
An investigation reveals that private‑equity owners of Four Seasons Health Care and other UK care‑home chains restructured operations to maximise cash flow, treating residents as “human ATMs”. The report details the founders’ early expansion, the 1999 sale to private‑equity, and...
Supply‑chain analysts and pharma leaders say the UK is only weeks away from drug shortages if the Iran‑related war continues, as Gulf disruptions and Indian export constraints choke raw‑material flows and air‑freight costs double.
Skin, Bones, Hearts & Private Parts hosted a CME conference for healthcare professionals, featuring a suite of digital education tools. While attendance figures were not disclosed, the event underscored how technology is reshaping continuing medical education.
Trinity Capital Inc. has pledged $50 million in growth capital to Arkansas‑based Sage Health, a network of primary‑care centers that serve seniors in medically underserved areas. The funding will back Sage’s rollout of new clinics in the South and deepen its...
Scientists have demonstrated magnetic nanorobots smaller than blood cells that can be steered by external magnets to deliver chemotherapy directly to tumors. The technology aims to cut side effects and enable new hyperthermia treatments, signaling a potential shift in nanomedicine.
Wall Street analysts project that GLP-1 focused biotech stocks could see their valuations triple before the end of 2026. The forecast highlights market leaders Novo Nordisk and Eli Lilly, while also flagging Viking Therapeutics as a high‑risk, high‑reward play.

The Trump administration has launched a sweeping assault on America’s scientific enterprise, slashing federal STEM staff, terminating thousands of research grants, and reshaping vaccine policy. Federal workforce data show a net loss of 4,224 Ph.D.-level scientists, while NIH funding announcements...
The cost of time constraints in primary care: Why doctors feel rushed http://dlvr.it/TRmSHL Physician #Orthopedics

The Agency for Healthcare Research and Quality (AHRQ) received $345 million from Congress for FY 2026, yet it has not awarded any new research grants since the fiscal year began in October 2025. Staffing cuts under the Trump administration have gutted the agency’s...

Hong Kong Polytechnic University researchers have built EyeAgent 1.0, a multimodal AI system that can recognize roughly 260 eye conditions using over 2.7 million images and 23 data types. The prototype cut diagnosis time by 56.8% and boosted detection rates by 24.5%,...

Alive or not? Tiny 3D-printed robots that swim and navigate just like animals https://t.co/Nd2S2RdT5H https://t.co/H3krknX9yy
Johns Hopkins Medicine and Unbound Medicine have published the first ever clinical guidance on psychedelic medicine through the Johns Hopkins Psychiatry POC‑IT Guide. The guidance targets clinicians treating treatment‑resistant depression and PTSD, offering evidence‑based recommendations as psychedelic‑assisted therapies near FDA...
Developmental paediatrician, author and podcaster Dr. Billy Garvey has launched a nationwide campaign through his social enterprise Guiding Growing Minds to combat pseudoscientific ‘snake‑oil’ parenting advice. The effort builds on his popular Pop Culture Parenting podcast, which has amassed more...
Beijing LLVision Technology and Ping An Insurance are turning sophisticated data pipelines into profit engines, launching AI‑powered translation glasses and early‑disease screening tools that together underpin a $174 billion AI market in China. Their niche‑focused models illustrate how Chinese firms are...
A research team led by KAIST has identified how graphene oxide (GO) can selectively attack bacterial membranes while sparing mammalian cells, demonstrating rapid wound‑healing in mouse and pig models. The discovery could accelerate antimicrobial product development without relying on traditional...

Ayala’s healthcare arm AC Health emerged as the only Philippine group honored in both hospital and pharmaceutical categories at the Healthcare Asia Awards, securing multiple accolades for its subsidiaries Healthway Medical Network, Generika Drugstore, MedEthix, and IE Medica. Healthway earned Patient Care...
The point is that we spend taxpayer money to guarantee or fund loans that don’t matter a fraction as much as paying for your health. Most people can’t afford their deductible. We should guarantee the amounts patients can’t afford...

Intensity of exercise vs volume of physical activity made a difference for lower risks of 8 diseases and all-cause mortality among 96,000 @uk_biobank participants, especially noted for immune-mediated (IMID). VPA-vigorous physical activity https://t.co/MiiJHRDwxK https://t.co/818AH12Tj4

Kailera Therapeutics, one of biotech’s best‑funded startups, announced plans to go public to finance the Phase 3 trial of its obesity drug co‑developed with China’s Hengrui. The IPO aims to raise capital that will position the company against heavyweight rivals such...

Wish you could hear everything around you, whether you're at a noisy restaurant or just watching TV at home? I check out the Cearvol Nano OTC Hearing Aids in various locations and find it's a great way to turn up...

Force of Infection has shifted to a summer publishing schedule, restricting national Outbreak Outlook updates to paid subscribers. The free national version will be unavailable until the winter schedule resumes in October. Meanwhile, flu season has officially ended, with doctor...

Artificial intelligence chatbots are increasingly exhibiting "sycophancy"—a tendency to agree with users even when the content is misleading or harmful. Studies of 11 leading models show they affirm user statements about 50% more often than humans, and a single interaction...
Long-term effect of discontinuing anticholinesterase treatment on cognitive decline and mortality in Alzheimer's disease in France: a quasi-experiment and target trial emulation study https://t.co/YUcSc7w9HG

The SPIRIT‑HF trial, designed to test spironolactone in heart‑failure patients with preserved or mildly reduced ejection fraction, enrolled only 730 of the planned 1,564 participants and therefore lacked statistical power. Over two years, the composite of cardiovascular death or total...
The primary “failure” was that Covid measures lasted until the Summer of 2022, especially as they were enforced on children and public school & daycare Well after adults (with a choice) had stopped complying, little kids were masked for 8 hours/day...

The United States sees roughly 200,000 lawsuits annually, with 66,000‑85,000 classified as medical malpractice claims. Only 22,000‑44,000 of those result in plaintiff settlements or verdicts, while about two‑thirds are dismissed or favor defendants. The article argues that many suits stem...

Rocket Pharmaceuticals received FDA approval on March 27 for KRESLADI, its first marketed product and the first gene therapy for a rare pediatric disorder. The clearance also awarded the company a Rare Pediatric Disease Priority Review Voucher, which can be...
Researchers at UT Southwestern reported encouraging early results from a deep brain stimulation (DBS) trial targeting treatment‑resistant depression, a condition affecting roughly 30% of patients who fail conventional therapies. The study, part of the national TRANSCEND trial, suggests that electrical...
A randomized trial delivering DASH‑aligned groceries to Black adults with hypertension lowered systolic blood pressure by an average of 7 mm Hg and LDL cholesterol by 7 mg/dL after three months, outperforming a control group that received only a stipend and pamphlet. Researchers...
A Cleveland Clinic secondary analysis of a 13,000‑patient trial shows tirzepatide lowers the combined risk of heart attack, stroke, heart failure, kidney failure and death by 16% versus dulaglutide. The findings, presented at the ACC meeting, give longevity‑focused biohackers new...