Optimal Nightly Sleep: 7‑8 Hours for Health
Sleep is essential for good health. Do you know how many hours of sleep are recommended each night?🤔 Is it 5, 6, 7 or perhaps 8 hours? You'll find the answer in this video. 📹 https://t.co/q1o9q3o11h #sleep #Health #lifestylemedicine #HealthCoach #MedTwitter #Wellness https://t.co/M4rLRlBy1Z
From Trial‑and‑Error to Predictive Cell‑Fate Engineering
We’re still engineering biology by trial and error. SynBioBeta 2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here: https://t.co/8abYWJ18mc @MichaBreakstone is building a model to predict cell fate with his new...
Pay‑to‑play Book Promotions Are Scams
It's a scam if someone asks you for money to feature a book in a store. It's a scam if someone asks you to pay to be included in a festival. It's a scam if someone asks you to pay...
Value Daily Effort Over Immediate Results
"Don't judge each day by the harvest you reap but by the seeds that you plant." Robert Louis Stevenson *Special thanks to the Bloomberg terminal.
Cellular Rejuvenation Could Shift Medicine to Youthful Resilience
Cellular rejuvenation may redefine medicine—not by treating disease, but by restoring youthful resilience at the cellular level. But science, safety, and hype are colliding. Worth the read (gift link) : 👇 https://t.co/7JGNdhFsFP via @NYTimes
Silence the Mind; Let the Soul Guide Healing
The soul always knows what to do to heal itself. The challenge is to silence the mind. ~ Caroline Myss #mindfulness https://t.co/zb86eicV7X
Troy Carter Predicts AI’s Impact on Music Industry
I sat down with troycarterofficial We covered it all: AI, streaming, artists, catalog sales, and what’s next in music. You can listen to our talk tomorrow, April 28 on Trapital, wherever you get podcasts. This talk was recorded in Austin during...
Lithium Interaction Poses Major Seizure Risk with Psilocybin
Most physicians were never taught psilocybin in medical school. Their patients in three states can now legally access it. Oregon's program has been operating since summer 2023. Colorado's healing centers came online in 2025. New Mexico passed its Medical Psilocybin...
Autologous iPSC Dopamine Cells Boost Parkinson’s Function without Immunosuppression
I’ve been following @jeannefrances's work for years, and what @AspenNeuro just reported out of Copenhagen is the kind of result that changes a field. Twelve months after receiving their own reprogrammed dopamine neurons, eight Parkinson's patients are showing real, measurable...
Seeking Top Dallas, Tyler, Abilene Recommendations
Heading to Texas this week, with stops in Dallas, Tyler and Abilene. Hit me with your recommendations: Record stores, restaurants, etc.
Skipping College? You Must Self‑Educate, Startups Won’t
If you skip some or all of college to start a startup, it's on you to develop your mind the way college would have. And that's not something that happens by default in most startups.
Patagonia Turned Customers Into Catalog Models
Reading "Dirtbag Billionaire: How Yvon Chouinard Built Patagonia, Made a Fortune, and Gave It All Away" by @dgelles One interesting story in it about how they used photos of their customers using the gear as calalog models. https://t.co/yoUJD3B6yj
Infinite ROI on Longevity, Yet We Plan Vacations Instead
Question: What's the ROI on preventing your own death? Answer: Infinite. Yet 99% of people spend more time planning vacations than planning longevity.
When Is It Acceptable to Discard Gifted Books?
I know I can be sassy sometimes but I have a GENUINE QUESTION about book PR etiquette. Under what circumstances is it ok to get rid of a gifted book?
Treat Employees Like Owners to Boost Their Performance
Once you understand this truth as an owner … you and your employees can both win ❤️❤️❤️‼️ pass this onto a business owner … When I was a kid my dad used to talk about being upset about his...
Metabolic Illness Can Nullify Calorie Deficits, Study Shows
came across a reddit post from someone who stopped losing weight and gained a bunch back while being in "a deficit". turns out they had a metabolic illness that was the issue, as soon as they started treatment they started...
Elliot Hershberg Returns to Lead AI Protein Dynamics Session
Why has @ElliotHershberg been coming to @SynBioBeta for the past 4 years in a row?? Elliot is a Partner at @AmplifyPartners and one of the sharpest minds at the intersection of biology and capital. He'll be moderating one of the...
Burnout Comes From Feeling It's Never Enough
It took me a long time to figure this out so I hope this helps you... You're not "burned out" because you do too much. You're burned out because you feel like its not enough.
HIIT Boosts Brain Health in Heart Disease Patients
The Utility of High Intensity Interval Training to Improve Cognitive Aging in Heart Disease Patients “the physiology related to cerebral blood flow regulation and cognitive decline in adults with cardiovascular disease and heart failure, and how HIIT may provide a more...
Embodied AI Takes Flight on the ISS
Robot Talk Episode 146 – Embodied AI on the ISS, with Jamie Palmer by Robot Talk @RobotTalkPod https://t.co/40Pf8nnScz
Marvel Still Scores Massive Openings Despite Post‑Endgame Doubts
This is a massive oversimplification, but for all the hand-wringing about the post-Endgame MCU box office, Marvel still delivered the 12th (Doctor Strange 2) and 14th (Wakanda Forever) biggest openings ever. Impressive.
Grief Reveals Love’s Depth, Not Mental Dysfunction
Grief is part of the human experience. If you love, you will lose. And when you do, the pain is inescapable. It can be disorienting, overwhelming, and in the case of acute grief, the symptoms can even resemble something like...
Avoid These 7 Fatal Endings to Save Your Novel
A bad ending can turn what would be a five-star novel into a flop. And that's all your readers will remember, no matter how brilliant the rest of the story was. That's why your ending HAS to land. Here are the 7 weakest...
Bipartisan Backing Pushes NASA, Budget Seen as Insufficient
Upshot of H Approps CJS hrg: bipartisan enthusiasm for NASA, esp Artemis (several reminisced abt Sputnik and Apollo 11) and for Isaacman; most think budget req too low ("disappointing" per chm Rogers); lots of support for STEM. Isaacman defended the...
Louisiana Cuisine: Soulful Traditions that Keep Lines Buzzing
Louisiana doesn’t just have soul. It cooks with it. This is a place where recipes are remembered and passed down, where the best meals come with a line out the door and a room full of regulars who know exactly why...
Self‑investment in 2026 Yields Real Returns
I know there's an old Warren Buffett around "the best investment you can make is in yourself" and I am fully leaning into that in 2026. It's already paying off 🚀🚀
Every Day Counts: Small Steps Toward Your Dream
I can't remember one single day in the past 40 years that I didn't move at least a tiny bit closer in the direction of my dream. What did you do today to get you closer to your dream?
Watch SynBioBeta2026 Live Anywhere, No Travel Needed
Visas. Travel costs. Time away from the lab or the office. Not everyone can make it to San Jose for #SynBioBeta2026 That's exactly why we built the livestream. 160+ sessions. 200+ speakers. Three days of Main Stage content streaming directly to your...
Discovered Deasvail's Rare Self‑Titled Vinyl Debut
It took me a while to track this one down: @deasvail’s self-titled debut album (and only vinyl to my knowledge). #ChambersMusic https://t.co/iiRoZ5SxqJ
Same Camera as Artemis II, Yet My Moon Shots Falter
I used the same camera to photograph the moon as the Artemis II astronauts, and it's probably the closest I'll ever get to going into space — but it also showed me I've got a lot to learn about astrophotography...
Start These Habits Now for a Future‑Ready Life
What every teenager should be doing right now to set themselves up for the future.
Exclusive: The Catch Rom‑Com Starring Stone, Pine Arrives Spring 2027
EXCLU: Universal dates rom-com THE CATCH starring Emma Stone and Chris Pine for spring 2027 https://t.co/GLIIIfEjKE
The Sheep Detectives: Surprisingly Strong Craig Mazin Thriller
THE SHEEP DETECTIVES is a lot better than it seems, i cannot stress how much this movie was written by craig mazin, as in chernobyl’s craig mazin my review: https://t.co/aQRlxRxDNE https://t.co/7eOTTJZefU
Life, Health, Love, Peace, Wisdom: Our True Gifts
The first gift is life. The second gift is good health. The third gift is to love and be loved. The fourth gift is peace of mind. There are no other gifts that matter as much. The fifth gift is...
Adapt or Be Replaced: Learning Beats AI
AI won’t replace people who keep learning. It will replace those who stand still. The biggest risk today is not change. It’s failing to adapt. https://t.co/oS3XXOc6fA
Stable L:P Ratio in Zone 2 Signals Metabolic Health
Lactate accumulation is not a sign of failed aerobic metabolism. It is a sign of a mismatch between glycolytic flux and mitochondrial substrate entry and oxidation. During Zone 2 exercise, lactate production increases, but because mitochondrial oxidation keeps pace, pyruvate...
Bedtime Meltdowns: Kids Releasing the Day's Stress
Say it with me: My child losing it at bedtime isn't a behavior problem or a sign I'm failing as a parent. It's the last exhale of the day. They're emptying out before they rest.
Dietitians Turn Influencers as Fitness Gurus Overprescribe GI Fixes
"Why are dietitians trying to be influencers?" Because fitness influencers are out here trying to tell people that their anxiety might not need an SSRI, just some GI mapping. 😑
Global 100% Renewable Roadmaps Cut Costs and Save Lives
Infographic map linking roadmaps for transitioning 150 countries to 100% WindWaterSolar for all energy purposes while reducing annual energy costs, social costs, energy use, and mortalities and morbidities. https://t.co/8j5oVvZeUu Here's the paper: https://t.co/yt6XQ531Fu
New Kanye’s Work Lacks Vision and Spiritual Depth
"Bully" was not good enough to force any sort of mass reckoning. This was true of both "VULTURES" just as it was true of both "Dondas." [They're] works devoid of vision, of idiosyncrasy, of any sort of spiritual center." @paulxt on the...
Madison Campaign Targets 27 Emmys, Pfeiffer Leads, Russell Returns
‘The Madison’ Launches 27-Emmy Category Campaign, Led by Michelle Pfeiffer — as Kurt Russell Eyes First Nom in 47 Years (EXCLUSIVE) https://t.co/v9R50CDknK via @variety
Mid‑career Men Often Prioritize Spouse over Leadership Growth
It's been awhile since I've had 1:1 exec coaching clients, but I'm working with a couple of client orgs where leader dev is part of the performance improvement puzzle. And what never, ever, gets old for me as a career and...
Colorado State Unveils World's Highest-Intensity Laser Hub
It was great to visit coloradostateuniversity in Fort Collins to celebrate the construction of the Advanced Technology Lasers for Applications and Science (ATLAS) Facility. Colorado is home to cutting-edge scientific research, and this new facility will support students and innovation,...
Over Half of Gray Market Peptides Fail Quality Standards
New pre-print on gray market peptides using @finnrick_tests data: 41.6% to 71.1% of gray market peptide samples failed to meet basic quality criteria, and measurable endotoxin contamination was present in 15% of samples. @Krysia830073
Low Post‑Surgery Klotho Predicts Inflammation and Cognitive Decline
Lower levels of the anti-aging protein Klotho after surgery were strongly linked to higher inflammation and worse cognitive function in patients with postoperative cognitive dysfunction (POCD). This suggests Klotho could be a useful early biomarker—and possibly a treatment target—for predicting...
Raising a 79‑year‑old Adventurer Who Needs a Timeout
I am raising a 79 year old who does things like walk up a mountain or cross the border from the DR to Haiti on foot and honestly I want him in timeout.
Breast Milk’s Low Iron Is a Protective Design
People talk about breast milk being low in iron like it is a flaw. It's not. It is 100% by design. First, babies do not need much iron from milk in the early months because they stockpiled it in their liver...
Erasca Shows Promising 40% PDAC, 62% NSCLC Responses
$ERAS Erasca touts strong, though preliminary, results in trial of pancreatic and lung cancer therapy $RVMD 40% uORR in PDAC; 62% uORR in NSCLC https://t.co/90BkD7tBeN
Longevity Hype Outpaces Evidence; Cancer Risk Remains
This @NYTmag article on longevity science, reversing aging with cellular reprogramming, by @susandominus, is over the top. We have no proof that rejuvenation of a human organ is possible, no less the whole body, and there is risk of inducing...
Swap Shallow Breaths for Deep Breaths During Stress
When we are stressed+our sympathetic nervous system leads the way, we are in fight or flight mode. In this mode, we often take quick, short breaths, when what we really need is long, deep ones. Try to catch yourself when...