Blue Origin Reuses New Glenn Booster, Boosting Launch Cadence
Well done to Blue Origin on successfully reusing a New Glenn booster for the first time, key to ramping up launch rate. https://t.co/n1kEUv1MlE
U.S. Researchers Face Cuts as DHHS Fuels Pseudoscience
1/n For U.S. medical researchers, shrinking labs and bare budgets are the new reality. As I point out: antivaccine is just a foot in the door, DHHS hopes to take down U.S. medical science to prop up wellness influencers &...
21st‑Century Models Show Longevity Escape Velocity
Life expectancy is rising across the world. Some people think we’re on the verge of “longevity escape velocity” — where medical progress starts extending life faster than aging takes it away. But what do the actual models for the 21st century predict?...
MIND Diet Slows Brain Atrophy Over Ten Years
Adherence to the MIND diet and longitudinal brain structural changes over a decade: evidence from the Framingham heart study offspring cohort “In this prospective cohort study, greater adherence to the MIND diet was associated with slower brain structural atrophy, particularly...
Neuroscience Reveals Optimal Brain Training Methods
One of the most interesting neuroscience reads I have ever consumed. How you should train your brain.
U.S. BMI Trend Shows Obesogenic Environment Reaches Saturation
The secular trend of the body-mass-index of the U.S.-born population and the rise of an obesogenic environment, 1882–2021 "...The obesogenic environment has likely reached a saturation point..." https://t.co/r8UnMinOBS https://t.co/mAy5kcZSac
Refined Diets Damage Amygdala Memory in Aging Rats
The aged amygdala’s unique sensitivity to refined diets, independent of fat or sugar content: A brain region and cell type-specific analysis 👉 “Refined diets impaired amygdalar memory in aged rats, regardless of fat or sugar…” https://t.co/GfWLeVTb9z https://t.co/xLCIniZq5B
Two Virology Experts Host Unfiltered Academic Talk Tomorrow
If it’s possible to describe two middle-aged academic women discussing timely topics in virology as hard af, we totally are. First show with my fellow virus slanger @JumoDr tomorrow at 5 pm ET/2 pm PT. Here or at the other place:...
Regular Resistance Training Boosts Muscle Function, Hypertrophy, Performance
American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews 👇 FIGURE 2: Schematic representation of the modes of RT and the outcomes that are positively influenced...
WHO Labels Night Shift Work as Probable Carcinogen
“The link between lack of sleep and cancer is now so strong that the World Health Organization has classified any form of nighttime shift work as a probable carcinogen." https://t.co/179qEbvyZe
Whey Protein Boosts Weight Loss in Obesity, Review Finds
Effectiveness of Whey Protein Supplementation in Weight Loss Interventions for Patients with Obesity: A Systematic Review https://t.co/aWeSqmYfFL
Amgen's Potts Lab Unveils Universal Molecular Glue Platform
Next up #aacr26 is @pottslab from Amgen discussing their broad and diverse molecular glue & degrader platform “any target, every time” https://t.co/SfJ0jGYene
Controlled Disorder Enables Compact, Multifunctional Optical Metasurfaces
A mosaic metasurface design integrates eleven optical functions, claiming that controlled disorder can enhance performance and reduce space requirements in optical systems. https://t.co/1Gk4xSS7s1
Funding Global Cancer Research to Cure Every Patient
EVERY CANCER. EVERY PATIENT. EVERYWHERE. @ConquerCancerFd of the American Society of Clinical Oncology (@ASCO) raises funds to support the world's leading researchers who are improving treatments & discovering cures for patients around the world. https://t.co/du6r6gdsgV #ASCO26
NASA Shuts Voyager 1 Instrument to Extend 49‑year Mission
NASA turned off one of the instruments on Voyager 1. The decision is considered the best option to keep the 49 yo spacecraft operating while they finalize a plan -- the "Big Bang" -- to keep it going even longer. https://t.co/hyqr7StQI0
Tesla: Visionary or Fraud? Sensationalism Over Science
“[Tesla] was frequently criticized for making science sensate rather than cerebral. He was often extravagant in predicting fabulous inventions that he never delivered. Even the popular press treated him by turns as a visionary and a fraud.” https://t.co/KfwHLRci6j
Sinclair's 1g NMN: Myth Vs. Cellular Reality
David Sinclair is one of the smartest longevity researchers on the planet. I interviewed him here: https://t.co/dZCOAD5PLU and recently @tombilyeu released an interview with him here: https://t.co/F2pHBy9xuw... ...in which @davidsinclair says he takes 1g of NMN every morning. But some people say...
Exploring Abundant Futures with Longevity Visionary David Wood
A Roadmap to Abundant Futures: A Conversation with David Wood @dw2 is well worth your time. I have a lot of respect for him, having collaborated together, and his work with @LongevityEVF alongside @aubreydegrey, another great visionary, speaks for itself https://t.co/Jr4k0g9HnB https://t.co/qwgshYdPXT
Tesla's Electrifying Stunts: Hundreds of Thousands of Volts
“stunts in which electricity was made to spark alarmingly were common…Tesla was well known for a visually spectacular trick of passing hundreds of thousands of volts through his body “while flames flashed from his limbs and fingertips” by means of...
Sidewinder Cuts DNA Assembly Errors to One‑in‑Million
Biology's source code is DNA. For 40 years, we've been able to read it. Writing it, especially long, complex sequences, is still painfully slow, expensive, and error-prone. Current DNA assembly methods fail about once every 10 to 30 connections. Kaihang Wang's lab...
Custom 3D‑Printed Hydrogel Electrodes Boost Neural Signal Quality
3D-printed hydrogel electrodes tailored to individual brain structures offer improved fit and signal quality for neural monitoring, potentially advancing personalized approaches to neurodegenerative disease management. neurotechnology
DepMap's Future: PRMT5 Inhibitor Differences Unveiled
Excellent talk from Bill Sellers on future directions with DepMap. Interesting differences between different PRMT5 inhibitors (SAM & MTA) and how they compare with selective inhibitors #aacr26 https://t.co/xfmKVqEpp1
Late‑stage Oral Cocktail Adds 33% Lifespan in Obese Mice
An oral drug combination, including a senolytic (quercetin), NR, urolithin A, and alpha-lipoic acid, extended median remaining lifespan in mice by 33%. Important to note, however, that the mice were fed a high-fat "Western Diet" and the intervention started at 18...
Compass Needles Detect Tiny Fields, Spin Can Induce Precession
🧪⚛️ How sensitive is a compass needle at detecting magnetic fields? Can the total spin angular momentum lead to mechanical precession of a hunk of ferromagnet? Read on.... https://t.co/evd47M7UVk
AI-Powered Computer Vision Scales Wildlife Monitoring at Wind Farms
Spoor outlines its vision for AI-based biodiversity monitoring, using computer vision to scale wildlife tracking across wind energy sites. https://t.co/kVqY7yUOqm
Ultraviolet Breakthrough Sharpens Lasers for Nuclear Clocks, Autonomous Navigation
A new ultraviolet breakthrough improves laser precision, advancing nuclear clock research and opening possibilities for autonomous navigation in space and underwater environments. https://t.co/2B5ZM642CT
Oliver Zolman Discusses Cutting‑Edge Aging Research Insights
New interview, by the terrific Oliver Zolman who was for a time Bryan Johnson's main doctor and who knows a great deal about aging research too: https://t.co/LCenNXC9xg
NAD+ Rhythms Drive Sleep, Aging; Resetting Delays Decline
NEW PAPER: Ups & downs in NAD+ over 24 h dictates our body's clock & sleep but declines with age. Disrupting the cycle promotes mouse aging & restoring it improves fitness & metabolic function, pointing to "circadian reprogramming" as a...
Climate‑Driven Drought Fuels Migration and Conflict
"Drought, Migration and the Fall of Civilization: A Cautionary Tale" | Seemed appropriate to be re-upping this op-ed I wrote a few years ago for @thehill on the role of climate-driven conflict in the middle east: https://t.co/C8fyuYwyl6
Stress Boosts Yeast Offspring Fitness With Distant Parents
Massive yeast orgy to investigate mating preferences among different yeast strains, and resulting offspring fitness under different conditions. Under some stress conditions, offspring fitness improves with increased genetic distance between parents. https://t.co/r1SSb7xlq7
Artemis II Laser Links Offer Faster Data, yet Limited
Laser communication systems on Artemis II promise extreme data speeds compared to Apollo era radios, but still face environmental limitations. https://t.co/2Bb9dJrNrh
Trump EO Accelerates Psychedelic Research for PTSD and Addiction
Delighted to see the Trump EO easing research into psychedelics for PTSD, depression, and addiction. It was a prescient choice by Rick Doblin and others to explicitly research psychedelics for PTSD in veterans. Makes it so much easier to get...
CHIP Clones Accelerate Aneurysm Growth, Offering Preventive Target
We don't measure blood stem cell clones (CHIP) in the clinic. But some are linked with fast, expanding abdominal aortic aneurysms, identification of an underlying mechanism, and a potential preventive treatment @jclinicalinvest https://t.co/4rWlLuivBJ https://t.co/vasG9hc9DK
President Signs Order to Boost PTSD Drug Research
JUST IN: The president signed an executive order to ramp up research on drugs for PTSD and other mental health issues.
Androgen Receptor Density Drives Muscle Gains, Not Testosterone
Muscle androgen receptor density, but not testosterone, predicts muscle growth from resistance training In this 2018 study, testosterone, IGF-1, growth hormone, DHEA, LH, or DHT predicted muscle hypertrophy - muscle androgen receptor content did Muscles have androgen receptors that mediate hypertrophy through...
Starship Booster Packs Power of 177 GE90 Jet Engines
Booster 19’s 33 Raptor 3 engines produce as much thrust as approximately 177 GE90-115B jet engines. That’s one Starship booster equaling the power of 177 of the world’s biggest turbofans.
Dads Deliver Distinct Microbes to Their Babies
Most people assume the baby's gut microbiome comes from the mother. A lot of it does, especially early on. But a 2024 study tracked 73 infants and both parents for over a year and found that fathers are a consistent source...
Join Study to Deepen Your Metabolic Health Understanding
Here is a worthwhile study to better understand your metabolic health. Please consider joining it: https://hubs.ly/Q02J7v2Q0 @mimiohealth
Pennsylvania Turns Abandoned Wells Into Renewable Geothermal Power
Pennsylvania has up to 750,000 of inactive oil and gas wells. Now the state will use some of those wells to build a clean, renewable electricity source, enhanced geothermal. https://t.co/SGBLc8g4ck More on EGS https://t.co/yt6XQ52tPW
Optimized Type 2 Diabetes Care Boosts Health and Savings in Spain
Estimating the Clinical, Quality-of-Life and Economic Impact of Optimized Management of Type 2 Diabetes Patients in Spain https://t.co/L3QB4MJf57 https://t.co/pot0usHX7f
Joe Rogan's Text Spurs Federal Psychedelic Policy Shift
How a text from Joe Rogan helped remake the federal government's approach to psychedelics https://t.co/8j55tEgdx6
Solar Powers 75% of Renewables, Nearing Half Global Capacity
Renewables just hit 49.4% of global electricity capacity. 5.15 terawatts. Solar drove 75% of the new additions. Some people thought it was impossible.
Illuminating the Dark Proteome: Protein Sequencing’s Next Frontier
The Human Genome Project mapped our DNA. We still can't read most of our proteins. There are billions of proteins in biology we've never sequenced: no function known, no structure solved, no role in disease understood. They're not hypothetical, they're real...
Longevity, Uploads, or Death: Future’s Polarizing Choice
biological longevity vs. computational immortality vs. finite existence there is a fascinating growing debate among technologists/futurists about where we should invest in - living longer through chemistry or immortality through uploading our data and ultimately our “consciousness.” and then there’s a spiritually...
NovaSeq 6000 Two‑color Chemistry Creates T>G Artifact
NovaSeq 6000's two-color chemistry introduces a recurrent T>G substitution artifact that doesn't show up on HiSeq X10's four-color chemistry. Germline and high-VAF somatic calls are fine. Low-VAF mosaicism calls are not. https://t.co/9PknN8Vyrb
Never Confuse DNA Plus/Minus Strands Again
1/17 Confused by plus/minus strands, coding/template, or forward/reverse in DNA data? You're not alone. Here's how to never mix them up 🧵 https://t.co/4kVXfhJssL
Implausible Apple Cider Vinegar Weight‑Loss Study Retracted
Implausible Apple Cider Vinegar Weight Loss Study Retracted When a trial has results that defy basic biology, it’s reasonable to be skeptical. @PharmacistScott https://t.co/ahEkiEmP7l https://t.co/yVyazUwXou
Our Loss of Real Megafauna Makes Charisma Tragically Ironic
*Charismatic megafauna* is tragically funny given how many authentic members of that class we’ve extirpated.
Microfluidic Lens Rivals Electronics for Glaucoma Monitoring
Can a microfluidic contact lens match electronic systems for glaucoma care while staying comfortable enough for daily wear? https://spectrum.ieee.org/smart-contact-lens-glaucoma-microfluidics?share_id=9388906
Roll‑to‑Roll System Prints 300 Visible Metalenses per Second
A fully automated roll-to-roll platform now enables the production of 300 visible metalenses per second, overcoming key manufacturing barriers and advancing the scalable commercialization of flat optics for next-generation photonic devices. metasurfaces