Starship V3 Set for First Test Flight Soon
Starship V3 booster & ship will be ready for their first test flight in a few weeks
Hygiene Breakthroughs Face Ridicule Before Saving Lives
Soap & disinfectants have saved more lives than any therapy Mother deaths before Semmelweis: ~10–15% After Semmelweis (1847):~1–2% Doctors laughed at him. He went to asylum & died from a beating Breakthroughs are ridiculed until they become part of everyday life
1q22 Gain Predicts Poor Prognosis in Myeloma
Prognostic significance of acquired 1q22 gain in multiple myeloma [Oct 28, 2021] Hadiyah Y Audil et al. @myelomaMD Am J Hematol https://t.co/qUKCUdnZPH #mmsm #PrecisionMedicine #oncopath HT @EagleMyeloma https://t.co/vd0BVZ6bRq
1q Abnormalities Define Distinct Proteomic Landscape in Myeloma
Proteomic profiling revealed unique disease biology associated with 1q abnormalities in multiple myeloma [Apr 14, 2026] Mangalaparthi et al. @Nature_NPJ https://t.co/XTcJZIGFh6 #mmsm #PrecisionMedicine HT @Myeloma_Doc https://t.co/XyrxJ29elO
U.S. Grid‑Battery Output to Power All Renewables by 2026
U.S. grid-battery production has gone from 0 in 2024 to 145 GWh/year by the end of 2026, enough to provide batteries to support all wind and solar in the U.S. https://t.co/faeAUzMjZ8
Mobile Launcher Returns to VAB for Artemis III Prep
The Mobile Launcher is on its way back to the VAB today to start getting ready for Artemis III. Departed the pad at 8:11 am ET. https://t.co/ZeDzYf5S67
NASA Greenlights ROSA Support for ExoMars Rover
NASA has given approval for the Rosalind Franklin Support and Augmentation (ROSA) project to begin implementation. This is the addl support NASA is providing to ESA to get the ExoMars Rosalind Franklin rover w/drill to Mars. https://t.co/mBPdDblJzg
AI Learns Scientific Laws, Not Just Memorized Answers
With Sim2Reason, AI moves closer to how science itself progresses: not by memorizing answers, but by discovering the laws that generate them. 🚀🧠 Read more about the team’s work: https://t.co/CSFqdns1er
AI Trains Electron Microscope to Match Human Vision
A decade of imaging. Compressed into three months. Here’s how MIT CSAIL & Harvard taught an electron microscope to see like you do: https://t.co/qC3zVck0HF https://t.co/kMTptacRMD
DNA Circles in Cancers Show Accelerated Epigenetic Aging
30 years ago, we discovered circular DNA molecules 1. pinch off yeast chromosomes 2. multiply 3. sequester epigenetic regulators (eg sirtuins) 5. cause aging New review today @CellCellPress about DNA circles in human cancers - which are epigenetically older than normal cells https://t.co/VlkBWCFnPi
From Static Snapshots to Dynamic Protein Modeling
AlphaFold solved protein structure prediction. That's a snapshot. But biology isn't static. Proteins flex, shift, and interact across time. Drug targets have multiple conformations. Cells don't act alone. The next hard problem is capturing that motion, and building models that reflect...
Scientists Propose Abandoning GLP‑1 as Obesity Target
Researchers behind GLP-1 obesity drugs advance new approach: Drop GLP-1 as a target https://t.co/ADzYb2Zqal via @statnews
Super‑resolution Microscopy Visualizes Live‑cell Endoplasmic Reticulum
What does the endoplasmic reticulum look like in a live cell, thanks to super-resolution microscopy? @naturemethods https://t.co/HZ0Vf9ZpZa https://t.co/fT95huDwNP
Ageing Happens Unevenly Across Organs, Not Uniformly
Mosaic ageing: from organ-specific decline to the cause of death “A growing body of biomedical and evolutionary studies increasingly questions the notion of uniform ageing: rather than a whole-body (single) trajectory, ageing appears to occur unevenly across organs, tissues and even...
US Study Links Telomere Length to Genes, Traits, Geography
Genomic, phenomic and geographic associations of leukocyte telomere length in the United States [Mar 27, 2026] @NakaoTetsushi et al. @NatureGenet https://t.co/3b75zEElAP https://t.co/jWNwYRWkQv
Nigeria Taxes Heavy Vehicles to Curb Pollution, Spur EVs
Nigeria is imposing a new levy on buyers of heavy-engine vehicles, including SUVs and trucks, to price pollution, encourage EV adoption and boost tax revenue https://t.co/ofdTMwXoM3
First Large Rapamycin Trial Aims to Boost Human Healthspan
Finally—this is the kind of study the field has been waiting for. A 720-person randomized clinical trial testing low-dose rapamycin in adults 65+ is about to get underway at @UAZPharmacy , with the goal of answering a simple but critical question:...
Third‑generation T‑cell Engagers Advance Cancer Immunotherapy
Cancer immunotherapy keeps revving up. Now onto a 3rd generation of T cell engagers https://t.co/h05f8h3i8L https://t.co/PP5XE8WWDr
Strong Force Explained Simply, No Color Charge Needed
Can you explain the strong nuclear force without colors? The idea of a "color charge" confuses a lot of people, and the analogy certainly has its flaws. Here's how to understand the strong force without colors, and without group theory, too. https://t.co/4qKBpVpZCI
Empowerment in RL Linked to Bayesian Causal Models
New preprint of a paper with Eunice Yiu to appear in Philosophical Transactions A, Special issue: World models, 2026. The theoretical link between empowerment in RL and Bayesian causal models with cool new data. https://t.co/3sGo14sh1f
Liver Disease Emerges as Fourth Major T2D Complication in India
A recent study published in The Lancet Regional Health Southeast Asia highlights liver disease as the “fourth major complication” of Type 2 Diabetes (T2D) in India. https://t.co/BQPqgDInhe #research #diabetes #healthcare #india
NASA Bets on Blue Origin for Lunar Victory
For the first time, but probably not the last, NASA and the United States are counting on Blue Origin to deliver a meaningful win on the Moon. https://t.co/lBZt9oTdXy
Blue Origin Launches Project Quartz Global Ground Network
Thanks for playing along for a bit of fun. “Project Quartz” is a brand new, @blueorigin global network of ground stations and Operation Centers. Here’s pics of the first one about to go in. It will revolutionize space operations, but...
MLKL Damages Mitochondria, Accelerates Stem Cell Aging
New evidence shows that MLKL, a protein linked to cell death, drives hematopoietic stem cell aging by damaging mitochondria rather than killing cells, highlighting a novel target for preserving blood and immune health. stemcells
Self‑assembling Brain‑grown Electrodes Enable Light‑controlled Neural Interfaces
Scientists Grow Electronics Inside the Brains of Living Mice 🐁 💬 The technology harnesses the brain's own blood chemistry to assemble soft, light-controlled electrodes around neurons. 👉 https://t.co/OmbEwgnh3y https://t.co/Zi4qiX1efr
Titan's Gentle Breezes Make 10‑Foot Waves, Exoplanets Don't
A new model predicts that gentle winds on Titan could generate 10-foot waves in its hydrocarbon lakes, while similar winds on some exoplanets would barely disturb their dense, exotic liquids. planetaryscience
Shrimp‑Inspired Camera Enables Real‑Time Cancer Mapping
A new shrimp-inspired camera captures ultraviolet, visible, and near-infrared images on a single chip, enabling real-time identification of lymph nodes and potential cancer spread during surgery for more precise and less invasive procedures. medtech
Free 1,500‑page Quantum Tech Bible, Updated Daily
Ok I have a new update for which book to read if you want to really understand quantum technology. CON: it's 1,524 pages and updated like, daily? PRO: it's free. No email required. No paywall. Just download the PDF. Olivier Ezratty...
Infrared Light Essential for Health, Modern Life Deprives It
Infrared light is critical to health and longevity It penetrates through clothes deep into the tissue to: - support energy production - stimulate neurons - improve vascular function - help with skin rejuvenation - stimulate stem cells - support wound healing - lowers inflammation Unfortunately, modern living conditions are...
Eltrombopag Proves More Cost-Effective than IVIG Perioperatively
Cost-effectiveness of eltrombopag vs intravenous immunoglobulin for the perioperative management of immune thrombocytopenia [Jan 31, 2022] @ThisIsManraj et al. @BloodJournal https://t.co/2hr1CFmUro #ITP https://t.co/Fz6ZRjJHlk
Rilzabrutinib Shows Safety and Efficacy in Chronic ITP
Safety and efficacy of rilzabrutinib vs placebo in adults with [persistent/chronic] immune thrombocytopenia: the phase 3 LUNA3 study [Jun 12, 2025] Kuter et al. @BloodPortfolio https://t.co/hhnzXg3bqu #NCT04562766 #ITP https://t.co/IkjLnu1kTd
Elevated Lipoprotein(a Drastically Raises 30‑Year CVD Risk
Thirty-Year Risk of Cardiovascular Disease Among Healthy Women According to Clinical Thresholds of Lipoprotein(a) 👉"Multivariable adjusted hazard ratios for levels above 120 mg/dL vs below 10 mg/dL or above the 99th percentile vs below the 50th percentile (11 mg/dL) were 1.54...
Daratumumab Shows Safety and Efficacy in ITP
Safety and Efficacy of Daratumumab in Immune Thrombocytopenia (#ITP) [Aug 5, 2025] Tsykunova et al. @BloodPortfolio https://t.co/GHyJGG7YSe #NCT04703621 https://t.co/pBgjzTCGQl
Ianalumab Combined with Eltromb
Ianalumab [VAY736] plus Eltrombopag in Immune Thrombocytopenia [Dec 9, 2025] @CukerMd et al. for the VAYHIT2 Investigators @NEJM https://t.co/99urXh8agT #NCT05653219 #ITP https://t.co/qKKhwv4ofR
ROS Complex Assembly Complete, Roskosmos’ 2030s Ceiling
...And this is the "initial assembly complete" architecture for the ROS complex, which is probably the most we can expect from Roskosmos in the first half of the 2030s: CONTEXT: https://t.co/wVxTkUEbNa https://t.co/P8mCC1RKFr
Duchenne Kids Show Dramatic Improvement After Microdystrophin Treatment
A couple of weeks ago when I visited Solid Bio, they showed me some videos of Duchenne kids pre and post microdystrophin treatment that I was amazed by - but they weren't sharable yet. Bo just presented them at Needham...
Multi-Omics Integration: Complex Realities Beyond the Hype
Thread: Multi-omics sounds cool—until you actually try it. Here's are the nuances. 1/ You’ve got RNA-seq. Methylation. Proteomics. Time to “integrate” the data. But how? And why? Let’s break it down. https://t.co/Wxhcp6OJ68
UK Drops Carbon Tax on Gas to Cut Bills
The UK will eliminate a carbon tax on gas generators and industry as the government tries to slash energy bills while also decarbonizing the power grid https://t.co/zyUAcTQXdm
Anti‑amyloid Drugs Show Trivial, Non‑meaningful Cognitive Benefit
The effect of current anti-amyloid drugs vs Alzheimer's disease is "trivial" for cognitive function or dementia severity, not clinically meaningful, from a systematic @cochranecollab review of 17 trials, >20,000 patients https://t.co/9A6PeZOyAt https://t.co/c1PCOYZxws
April 16, 1942: Hofmann's Accidental First LSD Trip
On this date April 16 in 1942, Albert Hofmann, while researching the synthesis of a lysergic acid compound, LSD-25, inadvertently absorbed some of it through his fingertips and experienced the first known LSD trip. Photo: AFP. #OTD https://t.co/ODWtsp2HtN
East Coast Heats up; Midwest Battered, Bigger Storm Friday
While New York and the East Coast bake under an early-season heat spell, the Great Plains, Midwest and parts of the Northeast were pounded by wind and hail Wednesday and face a larger threat Friday https://t.co/q7eRVCdX7V
Dark Energy Tool Delivers Unprecedented 3D Universe Map
This dark energy tool just created the most comprehensive 3D map of our universe ever: 'A major paradigm shift' | Space https://t.co/dLwwXPjfzQ
GLP‑1 Drugs Don’t Disproportionately Reduce Functional Muscle, DXA Misleads
1/2) New research suggests GLP-1 weight loss drugs probably do NOT cause disproportionate loss of functional lean muscle. The confusion has arisen from the fact that DXA scans capture and pool a lot of different organs and tissues into the category...
Join Our Autonomous Labs Q&A Session Today
Excited to share details on our Autonomous Labs and do Q&A today for @SLAS_Org ! Can register at link below 👇
Progress MS-32 Adjusts ISS Orbit for Soyuz Missions
Progress MS-32 conducts ISS orbit correction in preparation for Soyuz MS-28 landing and Soyuz MS-29 launch. DETAILS: https://t.co/pRxO5i4W6h https://t.co/67eNSveV1q
Roche Initiates New Elevidys Trial Targeting EU Approval
Roche to launch another Elevidys trial, with eyes on European approval https://t.co/eAANNiihpt via @DrewQJoseph $SRPT
Soyuz‑5 Launch Window Closes Amid Swirling Rumors
The inaugural launch of the new Soyuz-5 launch vehicle approaches the end of its available window without any official news, so I tried to untangle a morass of rumors and hints about the zig-zag path to flight for our subscribers:...
Stenting Advances Treatment for Post‑thrombotic Syndrome
Stenting for Post-Thrombotic Syndrome — A Step Forward {Editorial} [Apr 13, 2026] Flumignan & Nakano @NEJM https://t.co/w559CHaTON #NCT03250247 #VTE
Endovascular Therapy Shows Promise for Post‑Thrombotic Syndrome
Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial [Apr 13, 2026] Vedantham et al. for the C-TRACT [Chronic Venous Thrombosis: Relief with Adjunctive Catheter-Directed Therapy] Trial Investigators @NEJM https://t.co/Ayd4Fa0ARl #NCT03250247 #VTE https://t.co/6iD1NUQdgX
Columbia's First Unpowered Landing: A Historic Glide
45 years ago.. April 14, 1981..spacecraft with no engines glided down and touched down like a giant paper airplane on a dry lakebed in California. Space Shuttle Columbia on STS-1, the very first Shuttle mission, coming in hot over Rogers Dry...