Modifying Gut Microbiome Boosts Memory, Slows Dementia
As a medical school professor, I teach that the gut-brain axis is real. But even I was surprised by this. A review in Nutrition Research confirmed: reshaping the gut microbiome can enhance cognitive performance and slow dementia progression. Key findings across multiple interventions: - Probiotics, Medit... https://www.news-medical.net/news/20260401/Gut-microbiome-changes-improve-memory-in-early-cognitive-decline.aspx GutBrainAxis #MetabolicHealth #Dementia #Longevity #HealthLongevitySecrets
Consensus on Amyloid Hypothesis Delayed Alzheimer's Breakthroughs
The Amyloid Hypothesis: How Research Consensus Cost Us Decades. A Dive Into The Likely Contributors to Alzheimer's... https://t.co/ctsXwZPJTX
Glacier Melt Proves Global Warming, Not Urban Heat Bias
Glacier ice loss is a global & well-documented phenomenon, including from the Greenland and Antarctic Ice Sheets. A very visible result of #globalwarming. But I’ve seen climate deceivers recently claiming warming is due to the urban heat island effect 🙄🤯…
Genomic Drivers of Venetoclax Resistance in T(11;14) Myeloma
Genomic mechanisms of resistance to venetoclax in multiple myeloma with t(11;14)(CCND1;IGH) [Apr 2, 2026] @MKaddouraMD et al. @lbaughn @BloodPortfolio https://t.co/qmI6giPG6K #mmsm #PrecisionMedicine https://t.co/hpwUcavTg9
Never-Married Individuals Face 70% Higher Cancer Risk
Does never-married raise the risk of developing cancer? That what a new report says with a incidence rate ratio (IRR) of ~1.70 in both men and women. https://t.co/lz3wgagNRA https://t.co/ymwPqXT19x
Artemis III's Initial Orbit Remains Undecided, Officials Say
“One of the questions is what the initial orbit will be for Artemis III." https://t.co/atoSFLDYEs
Invisibility‑Cloak Tech Boosts Optical Switching in Data Centers
The same technology that could be used to create “invisibility cloaks” has applications in data centers, speeding up optical switching. https://spectrum.ieee.org/optical-metamaterials-ai-data-centers
Lymph-Node CD8+ T Cells Amplify PD-1 Blockade in GI Cancer
PD-1 antibody-bound progenitor-exhausted CD8+ T cells in lymph nodes boost PD-1-blockade anti-tumor immunity in gastrointestinal cancer https://t.co/VKoxzy6oUq https://t.co/cQG2sLWtL2
Molecular Profiling Reveals Distinct Signatures in Biphasic FDC Sarcoma
Molecular Characterization of Biphasic Follicular Dendritic Cell Sarcoma [Apr 7, 2026] Hassan et al. Applied Immunohistochemistry & Molecular Morphology https://t.co/WFoJRnwhOk #oncopath
Voyager's 1970s Tech Outpaces AI Hype
Did you know the Voyager 1 spacecraft has been flying for 49 years and is now 15.5 billion miles from Earth—yet it still phones home with less computing power than your garage door opener? We're literally running humanity's farthest outpost...
New Plan Unveiled for Assembling Post‑ISS Russian Space Complex
The latest scenario for the assembly of the post-ISS ROS complex from Roskosmos and its prime piloted spacecraft developer RKK Energia. Context: https://t.co/81bSOWHp9D https://t.co/5GW8HQkApg
Every Biological Question Is Fundamentally Computational
🧵"All biology is computational biology." That sounds bold. But it’s true. Here’s why: https://t.co/sjibYRKxbM https://t.co/QZNlIFAnXb
NRH Prevents Age‑related Hearing Loss via Sirt3‑mediated Ferroptosis Suppression
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation https://t.co/MOqQblWYNM https://t.co/uhSMXRIxDK
Sharing Artemis II Coverage with Kids Is Pure Fun
it's a lot of fun to show all the Artemis II coverage (photos, interviews) to your kids. highly recommend.
Caffeine Boosts Endurance Performance: How It Works
There is a substantial amount of evidence that caffeine has ergogenic effects, especially for endurance performance but how exactly does caffeine work? Read the full blog: https://t.co/4MicON03gV https://t.co/U5RpJzg2n2
Hypothalamic Switch Determines Appetite, Influences Obesity Risk
As a medical school professor, this is one of the most eye-opening findings I've seen in metabolic research. UT Southwestern researchers discovered a molecular "switch" in the hypothalamus that decides whether brain cells become appetite-suppressing or appetite-stimulating. The transcription factor Otp directs......
Aging Is Evolutionary Program, Not Survival Strategy
Why do humans age and die when some species are practically biologically immortal? Josh Mitteldorf, PhD, is an astrophysicist-turned-biologist who has spent decades thinking about that question. One of his main insights is that aging doesn’t look like a system trying...
ARPA‑E Announces Record Fusion Funding Amid Trump Cuts
Exclusive via @axios' @AmyAHarder: DOE's ARPA-E will will today unveil record fusion funding even as President Trump seeks to cut other parts of the federal fusion budget. Link in next post. #energy #climate #AI
Larger Muscle Fibers Waste Away Faster than Smaller Ones
In animal models, the largest fibers in a muscle atrophy faster and to a greater extent than the smallest fibers. Also, the rate of atrophy is fastest initially (when fibers are larger) and slower later (when fibers are smaller). Fiber...
EDF Commits €240 M to Heat Pumps, Electric Trucks
France's EDF pledges €240 million in investment and funding for the adoption of heat pumps and electric trucks https://t.co/LJYnxSn5i7
Lithium Reverses ApoE4 Cellular Deficits, Merits AD Trials
https://t.co/r6JzHA1RxM with ApoE4/E4 from a sporadic Alzheimer's disease patient "Given the drug's demonstrated efficacy in reversing ApoE4-driven cellular vulnerabilities, lithium salt warrants further investigation for the treatment of AD." https://t.co/r6JzHA1RxM https://t.co/v2lE0XhN7n
Chinese AI Cuts China Emissions, Boosts US, Japan
China's CAS released an LLM for carbon emissions accounting. The model apparently reduces China's contributions to emissions but increases US and Japan's. Is it open source, has anyone looked at it to see how it differs? Wrapping this in increasing...
Teen Simplifies Higher Dimensions, Shattering Academic Gatekeeping
A 16-year-old just exposed a problem that goes far beyond physics. He explained dimensional reality in 9 minutes more clearly than most institutions have managed in decades. What struck me was not only how smart he was. It was how simple he made...
Fast Breeder Reactor Marks 20 Years Toward Clean Indian Energy
Congratulations to all scientists and engineers who have worked for over two decades to achieve this milestone. The fast breeder reactor is critical to securing long-term clean & affordable energy for a surging Bharat. Most important to prioritize safe disposal...
Molecular Evolution Explains Animal Aging Diversity
Molecular evolution of animal aging 🗣️"...As a step toward this goal, this field perspective outlines general biological mechanisms that help explain the variability in aging patterns and longevity across the animal kingdom..." https://t.co/mHVAlyQbfM https://t.co/NoronuZDaL
On the Brink of Interplanetary Travel, Life Amazes
We are on the verge of interplanetary space travel. What an incredible time to be alive.
Space Food: Early Uncertainty Tested by US and Soviet Programs
Eating in space was actually something they were not sure would work and was an early test objective of the American and Soviet space programs.
Targeting Liver ApoE Boosts Bone Healing in the Elderly
Neutralizing hepatic apolipoprotein E enhances aged bone fracture healing "Our work here identifies novel liver-to-bone cross-talk and a noninvasive, translatable therapeutic intervention for aged bone regeneration" https://t.co/KSzvkKOzZt https://t.co/1p0cXQlalT
ACL Tears Can Heal Naturally Without Surgery
The ACL CAN heal on its own. Without surgery. 53% of ACL ruptures managed with rehabilitation alone showed complete healing on MRI at 2 years. Patients who healed reported better sport function and quality of life than the non-healed group and better than...
Α‑Eleostearic Acid Acts as Senolytic via Ferroptosis
α-eleostearic acid as a senolytic via ferroptosis. Found in high concentrations in Tung oil (which is toxic) and in small amounts in Bitter Melon oil. https://t.co/FSCix3OZtD
Turmeric‑Ginger Coating Doubles Bone Bonding, Cuts Bacteria, Cancer Cells
Turmeric and ginger extract applied to titanium implants can double bone bonding in six weeks, eliminate 92% of surface bacteria, and sharply reduce cancer-causing cells, offering a promising advance for joint replacement and bone cancer patients. biomaterials
Neighborhood Disadvantage Accelerates Cellular Aging via CDKN2A
Neighborhoods with limited social and economic opportunities are linked to increased cellular aging, as indicated by higher CDKN2A RNA levels, suggesting that structural conditions may influence biological aging beyond individual lifestyle factors. publichealth
Plant Tissue Culture Constantly Reveals Surprising Cellular Tricks
Coolest part of plant tissue culture is that no matter how much experience you have, you will always learn something new about the strange things plant bits do when given some molecular encouragement.
Conjugated PUFAs Target Senescent Cells
Polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells “ Conjugated PUFAs α-ESA and its methyl ester selectively eliminate diverse senescent cells… These lipid senolytics reduce tissue senescence and extend health span in aged mice” 👉 Lipid peroxidation underlies selective vulnerability...
Follistatin: Dual Weapon Against Cancer and Muscle Loss
Follistatin protein, which plays a key role both in inhibiting tumors and promoting muscle tissue growth. https://t.co/OebCo6FSI7
KLF5 Drives Pancreatic Cancer Spread via Gene Rewiring
A gene called KLF5 may be a key force behind the spread of pancreatic cancer—but not in the way scientists expected. Rather than mutating DNA, it rewires how genes are turned on and off, helping tumors grow and invade new...
Fatty Acids Target and Eliminate Aging “Zombie” Cells
NEW STUDY finds certain fatty acids selectively kill senescent "zombie" cells. The molecules exploit a fundamental biophysical weakness in senescent cells, a totally new approach. Could we simply consume these moleculs to treat aging? ...🧵 https://t.co/EceCAfdlvz
Artemis II Just Got an Amazing Upgrade
I mean COME ON. Just when you think Artemis II can't get any better, this drops. 🥹
Shingles Vaccine Beats Geroscience in Reducing Dementia
a different take: the shingles vaccine lowers dementia and all cause mortality and it’s targeted to a specific virus, not the process of aging so far the data say the score is shingles vaccine 1, geroscience hypothesis 0 and I could say the...
Weight‑loss Drugs Boost Life by Aiding Sick, Not Slowing Aging
Weight loss drugs may increase human longevity but that's because they reduce the mortality of folks at the lower end of the lifespan distribution (i.e., unhealthy individuals), not because they delay the aging process. That's still valuable, but if this is...
New Cytotoxic Targets Unveiled at AACR26
Time to head off the beaten track at #AACR26 with our latest preview exploring novel targets and cytotoxics. The long climb up the hill may be worth it for some of them: https://t.co/l9tkdWvpuF https://t.co/M5B3RTW1wf
Artemis II Flyby Images Reveal Humanity’s Cosmic Awe
My favorite images from the #ArtemisII lunar flyby yesterday. Images that remind us of the immense majesty of the cosmos. Images that remind us of how small we are. Images that remind us of how special we are, how precious...
Russian Lunar Launch Delays Repeatedly Rehashed, Yet Unchanged
Russia media quote a RAN official today about the latest delay of Russian lunar missions, however all these "new" dates had already been known since at least January and reported here... and will certainly be delayed again: https://t.co/oxFsJRelFu
GWP20: Faster Climate Action for Methane Benefits Health
GWP20 for methane greenhouse-gas accounting is good policy in NY State & beyond, as Prof. Bob Howarth and I explain in a response (https://t.co/86Dm2bq6zw) to a recent claim that GWP100 should be used instead Both California and New York...
Russian “Starlink” Satellites Begin Maneuvering, Developer Remains Silent
A couple of "Russian Starlinks" from the 16-bird group showed first signs of maneuvers, based on the US data, but there has been no word from the developer about the status of the mission since its launch on March 23. UPDATES:...
Orion Spacecraft Snaps Backlit Moon During Solar Eclipse
The Moon, seen here backlit by the Sun during a solar eclipse on April 6, 2026, is photographed by one of the cameras on the Orion spacecraft’s solar array wings. https://t.co/3GkEIJ7NBT
Funding Hurdles Stall Needed Multi‑site BPC‑157 Trial
I can’t see any reason why a proper multi site RCT of BPC157 done by a few independent groups wouldn’t help clarify any real vs placebo effects. The challenge: no one wants to pony up the $ (more like $$$$...
Blueprint for Integrating Psilocybin Into NHS Mental Health Care
British Journal of Psychiatry Psychedelics in NHS services: exploring a model for real-world implementation of psilocybin https://t.co/6sgfqg66rt
First Human‑Seen Solar Eclipse During Lunar Flyby
Holy sh*t. A solar eclipse, seen for the first time by human eyes during a lunar flyby. The Earthlight illuminating the crescent of the moon and part of the spacecraft, the stars and planets in the background…I’m in tears 🤯 📸:...
First Glimpse of Orion Returning From Moon
This picture right here is, I think, one of the most important of the Artemis II mission since the Orion spacecraft is clearly behind and a distance from the Moon. It's the first time we could see what intergalactic travelers...