Science Social Media and Updates

Genomic Instability and Epigenetic Reprogramming Drive Vascular Aging
SocialApr 5, 2026

Genomic Instability and Epigenetic Reprogramming Drive Vascular Aging

DNA repair-driven epigenetic changes as a cause of disease is going mainstream. A general medical review on CVD says: Genomic instability & epigenetic reprogramming are the deep mechanisms of vascular aging. Intervention strategies are the most promising & complex interventions https://t.co/xbEytAnIUH

By David Sinclair, PhD
Helium-Atom Lithography Aims Beyond ASML’s EUV Limits
SocialApr 5, 2026

Helium-Atom Lithography Aims Beyond ASML’s EUV Limits

The ASML book author saw the next generation – Lace Lithography, using helium atoms shooting through a holographic mask to scale beyond what’s possible with light, where the wavelength is larger than atomic scale. “ASML is the only company capable of...

By Steve Jurvetson
Temperature Stress Accelerates Perovskite Solar Cell Aging
SocialApr 5, 2026

Temperature Stress Accelerates Perovskite Solar Cell Aging

How perovskite solar cells age under temperature stress #energysky -- via pv magazine global: https://t.co/MyYMTXAJ26

By Tor “SolarFred” Valenza
Artemis Escapes Moon Thanks to Sufficient Escape Velocity
SocialApr 5, 2026

Artemis Escapes Moon Thanks to Sufficient Escape Velocity

Good question in the press conf: once it's in the grip of lunar gravity how come Artemis gets out again later? Because it has escape velocity relative to the Moon. The Moon is dominating its motion, but it's going...

By Jonathan McDowell
AI Model Maps Cell Trajectories Driving Human Aging
SocialApr 5, 2026

AI Model Maps Cell Trajectories Driving Human Aging

Impressive temporal AI model of aging by @GladstoneInst Based on ~175M single-cell transcriptomes, the model predicts drivers of cell trajectories across human aging. Also great that the first author, Javier, trained in our lab. Always rewarding to see our alumni flourish.

By João Pedro de Magalhães, PhD
Satellite Lifetime Drops Sharply With Altitude, Study Shows
SocialApr 5, 2026

Satellite Lifetime Drops Sharply With Altitude, Study Shows

Today's calculation: how long does a satellite in a circular orbit stay up when it stops all reboost burns? Depends on a lot of things, especially solar activity, but let's average over all of that and do a Kaplan-Meier analysis...

By Jonathan McDowell
SIRT1 Activation Shows Promise for Age‑related Brain Disorders
SocialApr 5, 2026

SIRT1 Activation Shows Promise for Age‑related Brain Disorders

SIRT1 Activators as Geroprotective Agents in Brain Aging: Mechanisms and Therapeutic Potential "...SIRT1 could be a promising pharmacological target for age-associated brain disorders, warranting more robust translational studies to validate these findings in humans..." https://t.co/hGVxZ4RErM

By David Barzilai, MD PhD
Live NASA Artemis II Visualization Powered by X API
SocialApr 5, 2026

Live NASA Artemis II Visualization Powered by X API

New @X API + @Replit is lots of fun. @tannerlbraden built a @NASAArtemis II mission visualization w/ live @X feed & stats. https://t.co/ptLIf58yCr

By Amjad Masad
Optimizing Transcriptome Workflow with C Timing Tests
SocialApr 5, 2026

Optimizing Transcriptome Workflow with C Timing Tests

Now time to vibe some more. Working on some tests to see where I can speed up some steps to streamline the transcriptome workflow I'm envisioning. Asking the bot to do some wall-clock timings in C to peep a few...

By Sebastian Cocioba
Veteran Male Athletes Face Heightened Ventricular Tachycardia Risk
SocialApr 5, 2026

Veteran Male Athletes Face Heightened Ventricular Tachycardia Risk

Protecting older male athletes’ heart health “Veteran male athletes who have spent years training at high intensity may be at greater risk of serious heart problems while exercising, new University of Leeds research shows… Over the two years of the study, around...

By David Barzilai, MD PhD
Genetic Testing Confirms Autism, Not Vaccine Injury
SocialApr 5, 2026

Genetic Testing Confirms Autism, Not Vaccine Injury

My daughter with autism and intellectual disabilities was not “vax injured,” a made up term. In fact through Baylor Genetics her autism gene was identified and sequenced and similar to the >100 autism genes published in @CellCellPress https://t.co/93tE96LcmB

By Peter Hotez
Dermcidin Blocks Flu Entry via Conserved Hemagglutinin Site
SocialApr 5, 2026

Dermcidin Blocks Flu Entry via Conserved Hemagglutinin Site

Dermcidin, a natural antimicrobial peptide found in sweat, saliva, and tears, disrupts influenza virus entry by binding to a conserved region of hemagglutinin, suggesting a potential broad-spectrum antiviral defense mechanism. immunology

By Phys.org Threads
Dual-Assembly Hydrogel Enables Precise 3D‑Printed Regenerative Microfluidics
SocialApr 5, 2026

Dual-Assembly Hydrogel Enables Precise 3D‑Printed Regenerative Microfluidics

A dual self-assembly hydrogel enables precise 3D printing of stable, biocompatible structures with dynamic responsiveness and antimicrobial properties, advancing the creation of complex microfluidic channels for regenerative medicine. hydrogels

By Phys.org Threads
Polyphenols and Exercise Shield Fruit Flies From Alzheimer’s
SocialApr 5, 2026

Polyphenols and Exercise Shield Fruit Flies From Alzheimer’s

Polyphenol diet and exercise as neuroprotective factors in a Drosophila model of Alzheimer's disease https://t.co/oNhsshekPa https://t.co/o0Yltk6fMc

By David Barzilai, MD PhD
Obesity and Age Drive Peripheral Inflammation in Cognitive Impairment
SocialApr 5, 2026

Obesity and Age Drive Peripheral Inflammation in Cognitive Impairment

Peripheral inflammation in a Canadian cohort of neurodegenerative conditions: Occurrence, determinants, and impact "Peripheral low-grade inflammation was common, particularly in individuals with cognitive impairment; and obesity and age were the main drivers..." https://t.co/KvjFleW6t4

By David Barzilai, MD PhD
Seven Independent Origins of Cooperative Breeding in Tanganyika C
SocialApr 5, 2026

Seven Independent Origins of Cooperative Breeding in Tanganyika C

Cooperative breeding in Lake Tanganyika’s cichlids evolved independently at least seven times, with smaller, more vulnerable species developing group care strategies to enhance offspring survival. evolution

By Phys.org Threads
Ultra‑processed Foods Tied to Many Chronic Diseases
SocialApr 5, 2026

Ultra‑processed Foods Tied to Many Chronic Diseases

Large meta-analysis of ultra-processed food intake is linked to multiple chronic diseases, not just obesity�https://www.bmj.com/content/384/bmj-2023-077310

By David Sinclair
Four-Hour Batteries Deliver 14-Hour Storage at 0.28¢/kWh
SocialApr 5, 2026

Four-Hour Batteries Deliver 14-Hour Storage at 0.28¢/kWh

These data illustrate how concatenating 4-hour batteries, provides longer-term (in this case, 14 hours) of storage. In other words, 4-h batteries already provide long-duration storage, and the batteries are inexpensive (0.28 cents/kWh-grid-output for 15.8 GW/63.2 GWh of batteries)

By Mark Z. Jacobson
First Human Controls Cursor Using Only Thoughts
SocialApr 5, 2026

First Human Controls Cursor Using Only Thoughts

Neuralink Live Demo: First Human Controls Cursor Using Only Thoughts by @TechCrunch #EmergingTech #Technology #Innovation #Tech https://t.co/UjyvFM1XL3

By Ron van Loon
Cures Emerge From Incremental Advances, Not Single Breakthroughs
SocialApr 5, 2026

Cures Emerge From Incremental Advances, Not Single Breakthroughs

The media makes it seem like cures are one breakthrough away. In reality, cures come from smaller breakthroughs and improvements made by the work of thousands of scientists, drug developers and doctors. We’re witnessing this evolution in real time with...

By David Sinclair, PhD
Climate Action: Loving God’s Creation and Humanity
SocialApr 5, 2026

Climate Action: Loving God’s Creation and Humanity

On Easter, we celebrate God’s gift of life. The importance of loving and caring for life - including everyone from our sisters & brothers to wildflowers & birds - is woven throughout the Bible. But today climate is harming life around the...

By Katharine Hayhoe
Few Experiments, Symbolic Compression Built the Atomic Bomb
SocialApr 5, 2026

Few Experiments, Symbolic Compression Built the Atomic Bomb

Science went from the initial observation of radioactivity to a working atom bomb over 47 years via only about 9 distinct key experiments -- extremely few data points -- and symbolic models concise enough they would fit on a single...

By François Chollet
TESS Captures Early Outburst, Confirming Inside‑out Disk Model
SocialApr 5, 2026

TESS Captures Early Outburst, Confirming Inside‑out Disk Model

NASA’s TESS satellite captured the early outburst of black hole X-ray binary AT 2019wey, providing high-precision, continuous optical data that support an inside-out outburst scenario in the system’s accretion disk. astronomy

By Phys.org Threads
Aging and Parkinson’s: Collaborative Roadmap for Better Models
SocialApr 5, 2026

Aging and Parkinson’s: Collaborative Roadmap for Better Models

Unraveling the intersection of aging and Parkinson’s disease: a collaborative roadmap for advancing research models https://t.co/6W6iYEx0br https://t.co/eFhYxVvAuk

By David Barzilai, MD PhD
One Daily Drink Ages Brain by Two Years
SocialApr 5, 2026

One Daily Drink Ages Brain by Two Years

As a medical school professor, I need to be honest: there is no safe level of alcohol for your brain. A landmark study of 36,000 brain scans found that even one drink per day shrinks your brain -- and the damage...

By Robert Lufkin, MD
Extra Virgin Olive Oil Shields Brain via Gut Microbiome
SocialApr 5, 2026

Extra Virgin Olive Oil Shields Brain via Gut Microbiome

As a medical school professor, I used to tell patients to "eat healthy fats." But the type of olive oil matters more than we ever taught. A new study in Microbiome (Feb 2026) tracked 650 adults for 2 years and found...

By Robert Lufkin, MD
Artemis II Crew Shares Stunning Space Views
SocialApr 5, 2026

Artemis II Crew Shares Stunning Space Views

Gaze in awe and wonder at these shots being shared by NASA and the crew of the Artemis II. https://t.co/Qqhj7afCAA

By TechRadar
AI Pathology Predicts Chemo Response in Small‑cell Lung Cancer
SocialApr 5, 2026

AI Pathology Predicts Chemo Response in Small‑cell Lung Cancer

An AI-powered pathology tool can predict whether extensive-stage small cell lung cancer will respond to platinum-based chemotherapy using standard biopsy slides, enabling more personalized treatment decisions without additional procedures. lungcancer

By Phys.org Threads
Phase 3 Trial Tests Daratumumab
SocialApr 5, 2026

Phase 3 Trial Tests Daratumumab

.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/ClwxVAhSy0

By Mike Thompson, MD PhD
AI Trained on Birds Surprisingly Decodes Whale Calls
SocialApr 5, 2026

AI Trained on Birds Surprisingly Decodes Whale Calls

Scientists at @googledeepmind trained an AI algorithm to identify bird calls. They tried reusing the model for whale calls and found the model’s training carried over into a whole new species. https://spectrum.ieee.org/foundation-models-google-birds-whales

By IEEE Spectrum Threads
Psychedelics Show Promise for Schizophrenia Negative Symptoms
SocialApr 5, 2026

Psychedelics Show Promise for Schizophrenia Negative Symptoms

Psychedelics for treatment of negative symptoms and depressive symptoms in schizophrenia spectrum disorder: A narrative review https://t.co/fGpTLwF3DK

By Julie Holland
Women Need Their Own Longevity Blueprint, Not Male Models
SocialApr 5, 2026

Women Need Their Own Longevity Blueprint, Not Male Models

Women are not “mini-men.” That line from Dr. Jennifer Pearlman MD CCFP NCMP FAARM ABAARM stuck with me from our @Optispan_Inc Podcast conversation—and it sets the stage for a much bigger issue. For decades, medicine and biomedical research have often treated...

By Matt Kaeberlein, PhD
Silicon Elastomer Actuator Thrives in Space‑Level Extremes
SocialApr 5, 2026

Silicon Elastomer Actuator Thrives in Space‑Level Extremes

A newly developed silicon-based dielectric elastomer actuator demonstrates enhanced resilience to extreme temperatures and low pressures, supporting the advancement of soft robotic systems for use in space and other harsh environments. robotics

By Phys.org Threads
Skull Vibrations Could Become Future Biometric Passwords
SocialApr 5, 2026

Skull Vibrations Could Become Future Biometric Passwords

Vibrations in your skull may be your next password by Rutgers University @TechXplore_com Learn more: https://t.co/oRTnakuTjb #EmergingTech #Innovation #Tech #Technology https://t.co/qvg0gNKuw2

By Ron van Loon
Satellite Mirrors Threaten Global Sleep and Ecosystems
SocialApr 5, 2026

Satellite Mirrors Threaten Global Sleep and Ecosystems

Let Mother Earth sleep. Satellite mirror plans could disrupt sleep and ecosystems worldwide, scientists say https://t.co/w6OCTyPqcu

By Jeff Jarvis
Seeing Biological Age Data Drives Real Health Improvements
SocialApr 5, 2026

Seeing Biological Age Data Drives Real Health Improvements

Some doctors say wearables & epigenetic age tests aren’t useful because they aren’t clinically approved But a new study of 178 people over a year says otherwise When people saw their data & biological age, they changed behavior & saw measurable improvements...

By David Sinclair, PhD
Not All scRNA‑seq Zeros Are Dropouts—Distinguish Real Signals
SocialApr 5, 2026

Not All scRNA‑seq Zeros Are Dropouts—Distinguish Real Signals

Your scRNA-seq matrix is 90% zeros. You assume it is dropout. Some of those zeros are real biology. Some are your platform failing to capture transcripts. Treating them the same way will wreck your analysis. https://t.co/z9SDKz3ZZv

By Ming Tang
Levetiracetam Blocks Amyloid Beta via SV2a‑dependent APP Modulation
SocialApr 5, 2026

Levetiracetam Blocks Amyloid Beta via SV2a‑dependent APP Modulation

Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer’s disease models "...supporting the hypothesis that protein accumulation is a relevant pathogenic event in amyloid pathology..." https://t.co/bRqoZP1Qyf @ScienceTM

By David Barzilai, MD PhD
Longevity Escape Velocity Could Grant 50 Extra Healthy Years
SocialApr 5, 2026

Longevity Escape Velocity Could Grant 50 Extra Healthy Years

If longevity escape velocity arrives by 2033 (Ray K’s prediction), a 50-year-old today has a shot at seeing 2100. The prize: 50 extra healthy years of compounding knowledge, relationships, and impact. Worth optimizing for? Focus on a longevity mindset.

By Peter H. Diamandis
Future Peptide Therapy Needs Automated Multi‑dose Syringe
SocialApr 5, 2026

Future Peptide Therapy Needs Automated Multi‑dose Syringe

The peptide revolution will require a small (reservoir enabled) auto syringe that doses at intervals with multiple peptides throughout the day. Basically a parallel exo-somatic signaling system.

By Peter H. Diamandis
Best Diet Scores Add up to Three Extra Years
SocialApr 5, 2026

Best Diet Scores Add up to Three Extra Years

Healthy dietary patterns, longevity genes, and life expectancy: A prospective cohort study "Compared with the bottom quintile, achieving the top quintile of dietary scores was associated with 1.9 to 3.0 years of life gained at 45 years in men and 1.5...

By David Barzilai, MD PhD
Targeted Antivirals and Vaccines Needed for CMV-Linked Cognitive Decline
SocialApr 5, 2026

Targeted Antivirals and Vaccines Needed for CMV-Linked Cognitive Decline

Human cytomegalovirus infection and cognitive decline: insights from population and experimental studies 🔎"We advocate for targeted antiviral strategies and vaccine development to clarify its contribution to neurodegeneration." https://t.co/b7Qx9aj0K3 https://t.co/KMB9ITLEzW

By David Barzilai, MD PhD
Everyday Comforts on Earth Complicate Space Travel
SocialApr 5, 2026

Everyday Comforts on Earth Complicate Space Travel

I know this seems funny, but all these little things that we take for granted on the ground, are exactly what make space travel incredibly difficult.

By The Space Mechanic
Machine Learning Links Spironolactone to Reduced Fibrosis Risk
SocialApr 5, 2026

Machine Learning Links Spironolactone to Reduced Fibrosis Risk

Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics https://t.co/Ho2RL0RhO4 https://t.co/cHkogagDTt

By David Barzilai, MD PhD
C Regex Boosts Transcript Loading Speed Over Biopython
SocialApr 5, 2026

C Regex Boosts Transcript Loading Speed Over Biopython

Music to my ears. Finally squashed a slowdown by focusing on a C regex instead of the slower biopython bits. Took a lot of back and forths to find a solution but thats a substantial speed difference. This becomes substantial...

By Sebastian Cocioba
Approaching the Thickness Ceiling for Perovskite Solar Cells
SocialApr 5, 2026

Approaching the Thickness Ceiling for Perovskite Solar Cells

Pushing perovskite solar cells to the ultimate thickness limit #energysky -- via pv magazine global: https://t.co/I1mdkL0yWo

By Tor “SolarFred” Valenza
Earth and Moon Orbit a Shared Center of Mass
SocialApr 4, 2026

Earth and Moon Orbit a Shared Center of Mass

The relationship between the Earth and the Moon is a dynamic orbital dance governed by gravity, primarily influenced by the Earth's mass. While we often think of the Moon circling the Earth, both bodies actually orbit a shared center of...

By Vala Afshar
Doomism and Geoengineering Advocacy Now Converging, Says Hallam
SocialApr 4, 2026

Doomism and Geoengineering Advocacy Now Converging, Says Hallam

In #NewClimateWar (see excerpt below) I warned back in early 2021 of the growing doomism/geoengineering advocacy nexus. 5 years later, we're seeing it in spades. Witness for example this new commentary (https://t.co/PkgSaNNChT) by "Extinction Rebellion" founder Roger Hallam: https://t.co/HZIAXUYC25

By Michael E. Mann
Collision-Born Magnetic White Dwarfs Emit X-Rays Solo
SocialApr 4, 2026

Collision-Born Magnetic White Dwarfs Emit X-Rays Solo

Astronomers have identified a new class of stellar remnants—highly magnetic, rapidly rotating white dwarfs formed from cosmic collisions, emitting X-rays without a companion star. These findings may reshape our understanding of stellar evolution. astronomy

By Phys.org Threads