Japan Approves Conditional Stem‑cell Parkinson’s Replacement Therapy
Woah. I'm slightly embarrassed that I missed this for a few weeks. Finally there is approval, in a Large Nation, for a stem cell-based REPLACEMENT therapy for an age-related condition. The condition is, no surprise, Parkinson's, which I always highlight in talks as the archetypical one amenable to RepleniSENS. The approval is "conditional" (Japan's very sensible system essentially merges Phase 3 with Phase 4), but that's still huuuuge. https://t.co/q53TwN5BS7
Rice Engineers Turn Dead Spiders Into Necrobotic Grippers
Dead Spiders Reanimated as Necrobotic Grippers by Rice University Engineers by @IntEngineering #Innovation #TechForGood #EmergingTech #Technology https://t.co/pKca0ZPo05
Just-in-Time Decoding Enables High‑Threshold 2D Non‑Pauli Quantum Gates
Recent weeks have brought a range of new ideas in quantum error correction for fault tolerant-quantum computing, along with deeper exploration of their implications. We introduce a new approach: a method for achieving high-threshold decoding of non-Pauli codes aimed at...
Tianlong-3 Launch Unconfirmed Amid Failure Speculation
LAUNCH of Tianlong-3 from Jiuquan at about 0417 UTC. Speculation it has failed but no official info yet.
Personalized NAD Boosting Needed; Redox Fingerprints Reveal Disease
Dynamics of blood NAD and glutathione in health, disease, aging and under NAD-booster treatment “In healthy population (n=299;18-70 year-olds) redox metabolites follow normal distribution in blood and remain unchanged during aging. NAD-boosting increased 4-6 fold the blood NAD+ depending on individual,...
National Science Programs Spark Kids' DIY Space Curiosity
Watched the Artemis launch yesterday with my 8yo. Today he built a rocket out of household stuff and started explaining all the parts. Don’t underestimate how important national science programs are. 🚀
Capsule Robot Endoscopy Simplifies Exams, Reduces Patient Pain
#WhatsNext? This endoscopy in a capsule robot, makes it easier for doctors to fully examine patients. It also makes examinations less painful to patients. (GiGadgets) #Robotics https://t.co/IQr2WTjyj6
AI Poised for Paradigm‑shifting Breakthroughs Beyond Human Knowledge
Now this is really interesting. It gets at whether AI models will be able to not just push at the edges of human knowledge but actually take a leap beyond the current human understanding into paradigm shifting breakthroughs. No clear...
Severe Infections Independently Raise Dementia Risk, Study Shows
The role of noninfectious comorbidities in the association between severe infections and risk of dementia in Finland: A nationwide registry study "These results support the role of severe infections as independent risk factors for dementia..." https://t.co/7gG41XSiy7
Which Company Will Fund AI's Scientific Breakthroughs?
Which company’s dollars are more likely to lead an advance in AI for science? 🤔
NASA Announces Daily Mission Status Briefings (Schedule Linked)
NASA will have daily mission status briefings. The list is here, but times are subject to change: https://t.co/CR88eAwACM
Integrity Crew Shatters Isaacman 1400 Km Record 13 Minutes Post‑launch
Per a question asked in the presser, Integrity's crew broke the Isaacman height record of 1400 km at 2306 UTC Apr 1, a mere 13 minutes after launch.
Mono Infection Triples Risk of Developing Multiple Sclerosis
New study has strengthened link between infectious mono and Multiple Sclerosis. By analyzing 2 decades of health records, researchers found people who contracted mono as teenagers or adults were 3x more likely to develop MS later vs those who didn’t https://t.co/6DLZMEWyU6
H5N1 Bird‑to‑Cattle Spillover Traced Across US
So pleased to contribute to this preprint on H5N1 spillover from birds to dairy cattle from the Moo Flu Crew, led by the excellent @jepekar. We traced both B3.13 in Texas and D1.1 in Nevada and Arizona to look at...
Running, Not Coordination, Boosts Brain Neurogenesis
As a medical school professor, I tell students exercise is medicine. But a new study shows the TYPE of exercise determines whether your brain grows new neurons. Researchers compared treadmill running vs. coordination exercises at matched intensity. Published in Frontiers in Neuroscience: ->...
NASA Marks 10th Crewed TLI Since 1968
That is NASA’s 10th crewed translunar injection burn since 1968. TLI is the quintessential American maneuver.
Artemis II Will Cross Van Allen Belts—No Tails
YES Artemis II will fly through the Van Allen Belts and no the crew won’t all grow tails. #author #history #space #science #apollo
Nanosecond Electric Pulses Rejuvenate Aging Endothelial Cells
Nanosecond pulsed electric field applications rejuvenate aging endothelial cells by rescuing mitochondrial-to-nuclear retrograde communication https://t.co/DT8GXNLlxO
Artemis II Shines; Credit Goes to Michoud Assembly Facility
The Artemis II is undeniably badass. But can we take a moment to appreciate the Michoud Assembly Facility? https://t.co/aulWNkbYTR
Artemis II Launch Reveals SRB Staging and Early Moonrise
NASA has posted rocket cam views from the launch of Artemis II. Here's SRB staging and the Moonrise the crew observed at T+5 minutes. https://t.co/paJDONlg0a https://t.co/M9lkXnDjHu
1969 NASA Relied Solely on Sealed Fairchild Chip
And it was done in 1969 using a Fairchild semiconductor chip. As I have heard the story, NASA had to chose between either manual navigation or automatic navigation, because the chips had to in a sealed system to avoid moisture...
Ancient Ig-Like Domain Controls Disease-Linked SWI/SNF Complexes
a (presumably primordial) Ig-like domain regulates the disease relevant SWI/SNF chromatin remodeling complexes that's pretty cool https://t.co/Iit0Swrx0I
Fly-Inspired Vision Lets Tiny Robots Fly Smarter
Small robots that mimic the sensor-rich fly motion vision system could optimize flight dynamics without the need for complex computation. Learn more in Science #Robotics: https://t.co/HQUR8LdubY https://t.co/XCaZxNEWRV
Amazonleo Calls SpaceX Safety Concerns Disingenuous, Promises Response
.@Amazonleo to @FCC: @SpaceX concerns about safety of our orbit-insertion altitude are disingenuous, but we'll address them anyway. @Arianespace @ulalaunch @blueorigin @NASA @SpaceNav2.https://t.co/thBEYhMtho https://t.co/4TA3hcqlU6
Cocoa Activates Sirtuins to Shield Cochlea From Aging
Sirtuins mediate the reduction of age-related oxidative damage in the cochlea under a cocoa-rich diet 📢"These results indicate that cocoa protects against oxidative damage through Sirtuins." 🍫 https://t.co/MLRfhChFYy https://t.co/BPh3sETpFm
Even Veteran Astronaut Awed by Upcoming Lunar Mission
I’ve flown in space four times but still can’t imagine what these extraordinary humans are going to experience on their mission around the moon. https://t.co/fgQER6Vx6S
Fast Marathoners Lose More Weight than Slower Runners
I grew believing that any amount of dehydration is too much. A simple study changed my mind: faster finishers at a marathon lost more weight than slower finishers. “Inverse relationship between percentage body weight change and finishing time in 643 forty-two-kilometre...
Obesity, Bad Lipids, Inflammation, and Vascular Aging Linked to Depression
Associations of adiposity, atherogenic lipid phenotypes, systemic immune-inflammatory indices, and vascular aging markers with depression in US adults: NHANES 2005–2020 "Adiposity, dyslipidemia, systemic immune-inflammatory activation, and vascular aging were independently associated with depression." https://t.co/PdlWJxoHiY
Blocking KDM4 Reactivates Tumor Suppressor, Halts AML
Scientists have restored a silenced tumor-suppressor gene in mice with acute myeloid leukemia by blocking KDM4 enzymes, suggesting a potential new therapeutic approach that avoids harming normal blood cells. leukemia
Low‑Metallicity Atmosphere on Giant Exoplanet Defies Formation Models
A giant exoplanet orbiting a small star exhibits an atmosphere with unusually low metallicity, challenging current models of planet formation and suggesting limited mixing between its interior and atmospheric layers. exoplanets
UV Light Cuts Acrylic Recycling Temp, Boosts Circularity
A new UV light-based process enables efficient chemical recycling of acrylic plastics at lower temperatures, preserving material quality and reducing environmental impact for true circularity in applications like screens and construction. sustainability
JinkoSolar Hits 32.76% Efficiency with Perovskite‑TOPCon Tandem
JinkoSolar achieves 32.76% efficiency in perovskite-TOPCon tandem solar cell #energysky -- via pv magazine global: https://t.co/gJ3RJKEpOT
33 Simple
I’ve spent the last decade studying the biology of aging. 🧬 Here are the 33 simple principles for healthy aging that consistently show up in the research ↓
Scientists Map Full Plant Pathway to Psychedelic Tryptamines
Mind-blowing science: Complete biosynthesis of psychedelic tryptamines from three kingdoms in plants | Science Advances https://t.co/39mQdp1cFE
Seeking Alternative Tools for Genetic Code Sequence Search
Anyone know of software or a web server that can search a sequence for alternative genetic codes? Been trying to install Codetta https://t.co/Wd7IMD23Cy but can't get it running so looking for alternatives.
Allulose Lowers Blood Sugar and Boosts Satiety
allulose isnt just a low calorie sweetener - it also: 1) binds to GLUT2 receptors which lowers blood glucose levels 2) stimulates GLP-1 improving glycemic control and increasing satiety
Warming Trend Turns Weather Variability Into Record-Breaking Events
This is a great example of how internal climate variability (e.g. weather) on top of a long term warming trend leads to new records being set. If the US weren't warming over time the records here would be 3 ->...
Does Collagen Strengthen Muscle Connective Tissue?
Does collagen strengthen connective tissue in muscle? Protein ingestion can increase the synthesis of contractile proteins, but does the same hold true for connective proteins? https://t.co/DbUJVYNRUU https://t.co/CQ2qDGJV6H
ISS Sections Experience Varying Accelerations Despite Uniform Weightlessness
My first answer is no. It’s different weightless at Lagrange point and orbit - but you would never feel the difference. In orbit, different parts of ISS have different orbits technically and thus different acceleration. Same is tru near L1,...
Artemis II Begins TLI Burn, Reaching Lunar Distance
The Artemis II Integrity spacecraft is now coasting downwards and will reach perigee of about 195 km late on Apr 2. At 2349:50 UTC it will make the TLI (Trans-Lunar Injection) burn, a 388 m/s burn lasting 5m51s to raise...
Valine Restriction Boosts Healthspan, Extends Male Lifespan
Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice "Our results demonstrate for the first time that Val-R improves multiple aspects of healthspan in mice of both sexes and extends lifespan in males, and suggests that...
Fossil Fuels Consume 11% of Global Energy; Renewables Need None
To boot, 11% of all energy worldwide is used just to mine, transport, process, and/or refine fossil fuels and uranium. https://t.co/c3RjxqKhcO Whereas wind, solar, geothermal, and hydro require 0 such energy because wind comes right to the turbine, etc. So for anyone to...
Artemis 2 TLI Burn Approaches: Updated Mission Timeline
Timeline of Artemis 2 key events (in Mission Elapsed Time) is in NASA's press kit. https://t.co/dKNkKadt10 NASA is posting updates on the Artemis blog. https://t.co/WeDPP3en7T TLI burn is next major event ~7:35 pm ET today (1d1h37s post-launch) https://t.co/kQH3BiJIJG
US Space Force Confirms Russian Starlink Satellites Stay Near Rocket
Thanks to the US Space Force, there is finally tracking data for the "Russian Starlink" group, indicating that all 16 satellites are in their nearly original orbit, a few kilometers above the third stage of the Soyuz-2 rocket, which had...
March 2026 Ranks Fourth Warmest, 1.48°C Above Pre‑industrial
March 2026 was the 4th warmest March on record for the planet's surface in the ERA5 dataset, coming in at 1.48C above preindustrial levels. https://t.co/Z0Jja9ncx4
Muscle Loss Spikes After Inactivity, Not Just Aging
Muscle loss doesn’t just gradually decline with age. A lot of it may happen in ‘catabolic crises’ - sharp drops after periods of disuse like injury, bed rest, hospitalization, or stopping training. The real harm is not just aging itself,...
Brainless Clones: Expensive, Unethical, and Scientifically Useless
This thread explores many interesting aspects of brainless clones. It raises the issue of whether this is even useful (including as animal model) It surfaces the terminology "decorticate" which is what's in the literature.
Memory Chip Survives Lava‑Hot Temperatures, Defying Thermal Limits
New memory chip survives temperatures hotter than lava 🌋 😳 💬 The electronics inside your phone, your car, and every satellite currently orbiting Earth share one critical weakness: heat. Push them past about 200 degrees Celsius and they start to fail....
Collaboration Between Bioinformaticians and Wet Biologists Drives Science
🧵The most underrated superpower in science: Bioinformaticians and wet biologists working together. Here’s why it matters. https://t.co/PRuGiq6CbV
Exercise Restores Aging Mice Gut Microbiome, Cuts Heart Risk
Late-in-life treadmill training mitigates gut microbiome imbalances and cardiovascular disease risk in mice "Here we demonstrate that a 12-wk treadmill running program in older mice rejuvenates the gut microbiome and attenuates markers of cardiovascular disease (CVD) risk. Notably, specific microbial taxa correlate...