No Cosmic Hole Exists; Nebula Image Is Misused
The widely reported “hole in the Universe” is a lie It's 2026. There still isn't a hole in the Universe, and the famous nebula they always show when describing it doesn't have anything to do with the Universe at all. https://t.co/91kWOrNZTD
Fusion Plant Feasible by 2045 with Massive Effort
Fusion power plant possible by 2045 with massive effort, says science academy #energysky -- via Renew Economy: https://t.co/wmE6rq570P https://t.co/FjHhMUqKyq
Sharing Apollo 12 Gem, Seeking Lost TV Transmissions
Writing a talk that includes this gem from Apollo 12 so thought I’d share it! Also if you know where those TV transmissions might live let me know, Google has truly become crap as a search engine. #author #history #space...
Obesity Prevention Offers Far Greater Cancer Protection Than Expected
"A much stronger cancer-preventive potential of obesity prevention and control than previously established" https://t.co/QatHKVMbfz @JAMAOnc https://t.co/OQ62MunGTu
APOE4 Linked to Meningeal Lymphatic Dysfunction, In
1 of 4 people have an APOE4 allele, a risk factor for Alzheimer's disease. New evidence this is linked to abnormal meningeal lymphatic function, brain inflammation, and important sex-differences @NeuroCellPress https://t.co/mUUqLedS9V https://t.co/FADCoemvum
High‑Dose Psilocybin Outperforms Nicotine Patches Sixfold
One large psilocybin dose beat nicotine patches by 6x odds for smoking cessation. 82 otherwise-healthy cigarette smokers, 42 received a single high-dose 30mg/70kg psilocybin session, and 40 initiated an 8- to 10-week course of nicotine patch treatment. At 6 months; participants were 6x...
Parental Age Rarely Harms Offspring Fitness in Wild Reptiles
Parental age effects on offspring fitness in a wild population of a short-lived reptile G "adds to the growing literature suggesting that negative effects of parental age on offspring fitness may not be as prevalent as once thought, particularly in wild...
Soyuz‑5 Launch Delayed to March 29, Flight Early April
The rollout of the first Soyuz-5 rocket to launch pad Site 45 in Baikonur, Kazakhstan, was postponed from today to March 29, in turn, pushing its inaugural flight to April 2, at the earliest, according to Kazakh media. Context: https://t.co/DBcHRiQe36 https://t.co/S8p6AAE3IL
Allogene's Interim Data Hints at Off‑Shelf CAR‑T Breakthrough
This week's Biotech Scorecard: Allogene $ALLO: A preview of its April interim analysis. Very interesting (to me, at least) There just might be a path forward for off-the-shelf CAR-T therapy in B-cell lymphoma. Frontline consolidation. Read all about it: https://t.co/tcPFelUH3C
Gene Therapy Turns Aging Into Editable Code
Gene therapy isn't just targeting diseases anymore—it's targeting aging itself. The hallmarks of aging are becoming editable code. Longevity Escape Velocity isn't a fantasy. It's an engineering problem. And we're solving it.
Harvard's Light Chip Enables Sorting Mirror-Image Molecules
Harvard’s twistable light chip could give drug developers a new tool for sorting mirror-image molecules https://t.co/WkjjD38exo https://t.co/5kr4d9f6sa
AI Scientist Writes, Experiments, Publishes Papers Autonomously
As a medical school professor, I've spent decades writing papers and reviewing studies. Now AI can do it all -- start to finish. Researchers from Sakana AI, Oxford, and UBC just published in Nature: "The AI Scientist" -- a system that...
Eggs as Cheap, Scalable Factories for New Medicines
I have a story today about the quest to turn eggs into low-cost factories for medicines. Gift link: https://nyti.ms/4bzSabB
Code Ran Fine, but Biology Flagged Label Error
I almost sent a figure with wrong cluster labels to my collaborators. The R code ran perfectly. No errors, no warnings. I caught it because cluster 2 showed upregulated genes in RNAseq but reduced chromatin accessibility in ATACseq. Biologically, that's backwards....
TRIBE V2 Predicts Brain Responses to Any Stimulus
Today we're introducing TRIBE v2 (Trimodal Brain Encoder), a foundation model trained to predict how the human brain responds to almost any sight or sound. Building on our Algonauts 2025 award-winning architecture, TRIBE v2 draws on 500+ hours of fMRI recordings...
Exercise Beats Optional: Key for Prostate Cancer Survival
As a medical school professor, I can tell you: the textbooks got this one wrong. We taught that once you have prostate cancer, exercise is nice but optional. New data says it may be the most powerful tool in your arsenal. 828...
Lifespan Extension Doesn't Guarantee Morbidity Compression, Study Shows
“These findings challenge the assumption that lifespan extension necessarily compresses morbidity, highlighting the need to consider lifespan, healthspan, and CoM as endpoints when evaluating anti-aging interventions. We do not claim that life-extending interventions categorically fail to achieve CoM; rather, we demonstrate...
Ignoring Climate Risks Threatens 20% Global GDP Loss
The sad truth... This pattern is not limited to climate change. Too often, the economy stands above health, peace, environment and even people. Nothing seems to come before the economy... When it comes to climate, the economy is often treated as the...
Delhi's Weak Plan Stalls 2035 Emissions Progress
Meager new emissions reduction plans from New Delhi limit the prospects of major progress through 2035 from the three biggest polluting nations https://t.co/H7X2IWuZRQ
Menstrual Phase Influences GI Discomfort During Exercise
How does the menstrual cycle affect gastrointestinal symptoms during exercise? 🩸 This new study recruited 12 eumenorrheic females to complete 2 x 45-min bouts of a simulated football match on a treadmill ⚽️ Simulations were completed in… 1️⃣ Phase 1 (P1, days...
Genetic Atlas Reveals Why Certain Brain Regions Age Faster
For the first time, scientists have mapped how genetic factors drive aging in specific brain regions, revealing why some areas are more vulnerable to Alzheimer's and dementia. This detailed genetic atlas advances understanding of brain aging. neuroscience
Mini Brains Rewire to Balance Digital Pole
🔺 These Mini Brains Just Learned to Solve a Classic Engineering Problem 🧠 In a step toward biological computing, brain organoids rewired their networks as they learned to balance a digital pole on a cart. https://t.co/w2wHDTvIVp https://t.co/h51xTVlR4D
First Soft 3D Hydrogel Semiconductor Replicates Living Tissue
World’s First Soft #3D Hydrogel Semiconductor That Mimics Living Tissue by @tweetciiiim #EmergingTech #Innovation #Technology https://t.co/jt0fxgrrdt
NASA Prepares Artemis II Lunar Flyby Launch Next Week
NASA Gears Up for Artemis II Launch Around the Moon a Week From Now https://t.co/EkQMgSOIZJ
Top Epigenetic Clocks Predict All-Cause Mortality Risk
I'd still rather measure the actual biomarkers, but the best epigenetic clocks (PhenoAge, GrimAge, DunedinPACE) are consistently associated with all-cause mortality risk Another study was just published showing this: https://t.co/RZntDTn02c
Fish‑like Micro‑robots Poised to Revolutionize Medicine
Tiny Swimming #Robots That Move Like Fish Could Transform Medicine and Science by @IntEngineering #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/smfTSXZyHx
Inflammation Not Inevitable With Age, Environment Matters
Minimal Evidence of Inflammaging in Naturalistic Chimpanzee Populations 🐒"These results parallel recent findings from humans in demonstrating that chronic inflammation is not a natural consequence of aging but may rather be driven by environmental contexts that are mismatched to the evolutionary...
First Full GlyphAllo Data Reveal From Discovery to Human Proof‑of‑Concept
Proud of the work of our Seaport team & collaborators published today in @ScienceTM. This ~13 page peer reviewed paper is the first comprehensive data disclosure of our GlyphAllo™ program from discovery through initial human proof‑of‑concept.
Integrative Models Reveal Evolutionary Roots of Aging Variability
How and why does aging occur? Updating evolutionary theory to meet a new era of data "We argue that by incorporating richer biological detail to create more integrative predictive models, we can gain insight into expected future distributions of aging within...
Centenarians Show High Apoptosis, Low IGF‑1 Signaling
Interesting paper - looks at what's high and what's low in centenarians vs others. Of course this doesn't reveal what's causal vs simply a biomarker. High apoptosis signals, low IGF-1 pathways.
Red‑Light Therapy: The Real Science Behind the Hype
The surprising science behind red-light therapy — and how it really works. People are buying helmets, face masks, vests and beds that emit long-wavelength light. Beneath the hype, there is some interesting biology. https://t.co/JWV80QOuQU
Microtubules Direct Enzyme Access to Safeguard Chromosome Segregation
Microtubules actively regulate chromosome segregation during cell division by controlling enzyme access to substrate proteins, ensuring accurate attachment and separation, and preventing chromosomal instability linked to cancer. cellbiology
Professor Denis Migliorini Leads Fight Against Glioblastoma
So pleased that people like Professor Denis Migliorini @MiglioriniDenis are leading the fight against solid tumors such as GBM / glioblastoma: he is an inspiration. https://t.co/8ohKJG4mQq
Epigenetics Explains Unique Traits Beyond Identical DNA
Epigenetic modifications—chemical changes to DNA that do not alter its sequence—help explain why individuals with identical genes can develop unique traits and behaviors, shaping their own ecological niches and influencing evolutionary processes. epigenetics
Passion Fruit Compound Shields Mitochondria, Improves Mouse Memory
Alpha-amyrin, a molecule found in passion fruit, has demonstrated the ability to protect brain mitochondria and reduce memory loss in Alzheimer's mouse models, suggesting potential for future therapeutic development. neuroscience
Restarting SSRIs Improves Outcomes Over Med‑Free Approach
When we published our H2H in @NEJM Ian Jordan raised an excellent letter re SSRI discontinuation & how it might impact response. We looked & found he was right. Those who discontinued SSRIs and went back on (escitalopram) did far...
Study’s Bias: Excluding TAD Nonresponders, Uncontrolled Therapy
Here it is again. Amazing how researchers could get away with this back then. Regular systematic bias of excluding TAD nonresponders. Also note another thing inconsistent with core psychedelic trial period i.e., that Ps were allowed to continue psychotherapy outside...
Isaraerospace Launch Aborts Seconds After Liftoff; Cause Unknown
.@isaraerospace launch aborts at second of scheduled liftoff, cause unclear. countdown had been delayed by a boat in launch area earlier. https://t.co/TXLNBwmRVz
Nebulae Vary: From Star Birth to Supernova Remnants
This is the Crab Nebula. It's a supernova remnant — the leftover debris from a star that exploded. But not all nebulae are the same. Some form stars, some mark the death of Sun-like stars, and some block light completely.
2D Carbon Selenide Enables Competitive Sodium‑Ion Batteries
2D carbon selenide offers route to competitive sodium-ion batteries #energysky -- via pv magazine global: https://t.co/deTW0kC8Qd
New Debris Object Misplaced in Expected Launch Catalog Range
There's a new object cataloged as 68376 and tagged as a debris object from the 2026-009 ALSAT-3A launch; it's in the catalog number range I was expecting for the 2026-061 Rassvet launch, but no TLEs for that launch yet.
Microscopic Robot Delivers Targeted Drugs Inside Bloodstream
Microscopic #Robot Navigates the Bloodstream to Deliver Targeted Medication by @CeoImed #MedTech #Healthcare #HealthTech #Tech #Technology https://t.co/LBJeDdwTuq
Open Review Flags Flaws in Telomere‑river Longevity Study
The incredible study using "Rivers of telomeres" to rejuvenate tissues and extend lifespan in mice is now undergoing open peer-review. I did a review, pointing out issues with the methods and the lifespan curves. They're looking for more reviewers. https://t.co/KOiR4F85sT
CERN's FLASH Therapy Promises Faster, Safer Cancer Radiation
FLASH therapy at CERN harnesses particle accelerator technology to deliver ultra-fast, high-dose radiation treatment, potentially transforming cancer care with fewer side effects. https://spectrum.ieee.org/flash-radiotherapy
Open-Source DIY Guide to Building mRNA Vaccines
Inspired by the man who built a personalized cancer vaccine for his dog, I’ve written an open-source guide to DIY mRNA vaccine production: philfung.github.io/openvaxx Drawing on my background in running lab startups, the guide covers the entire process - from sequencing...
Bat-Inspired Denoising Lets Tiny Drone Avoid Invisible Obstacles
A bat-inspired approach denoises ultrasound echolocation signals, enabling a palm-sized drone to navigate challenging environments while avoiding transparent or thin obstacles. Learn more in Science #Robotics: https://t.co/utyw7UGfJ9 https://t.co/eesQvK3IJU
Scientists Move Minuscule Antimatter in Space's Void
Science is epically cool. Making the emptiest place in the solar system to move the tiniest, tiniest amount of antimatter.
AI-Driven Humanoid Robots Promise Universal, Elite-Level Healthcare
Humanoid robots + AI will mean everyone on Earth has access to better medical care than the richest person alive today. THAT is what abundance looks like.
Blueprint for Affordable, Accessible AAV Gene Therapy
When people ask "How can we make #AAV #GeneTherapy accessible and affordable" --> this is how 👇
New Review Links Β‑cell Stress to Type 1 Diabetes
Rethinking why the pancreas β-cells become vulnerable to autoimmune attack, leading to Type 1 diabetes. An illuminating review with ideas to counter β-cell stress @ScienceTM https://t.co/zn6a6wEg7u https://t.co/BV0LYnWRNL