
Changing Biological Age Unlocks Future Lifespan Gains
A new paper says lifespan gains will be small due to our biology That’s true - if we don’t change. But if we can change our biological age, the equation changes In 1700, we couldn’t imagine moving faster than a horse. Biology ruled. Then came the steam engine 🚂 🏎️ 🚀… https://t.co/9H9jYf6NJB
Lab Experiment Shows Distinct Energy, Momentum Cascades in Turbulence
A lab-based mini-atmosphere experiment demonstrates that energy and angular momentum cascade differently across scales, revealing behaviors in turbulent flows not captured by current atmospheric models. atmosphericphysics
Spanish Team Sustains Human Uterus Alive for 24 Hours
Scientists in Spain kept a donated human uterus alive for 24 hours using a machine that mimics the body's circulatory system, pumping modified blood through the organ.

US Obesity Prevalence Rises to 69% with New Metrics
Obesity (in the US) is much more common than prev thought: 69% vs. old 43% stat Based on new better definition that uses not only BMI but also anthropomorphic measures such as waist & ratios of it, which more accurately shows higher...

20‑Year Methane‑CO₂ Comparison Flawed; Separate Targets Needed
Using a 20-year period to compare methane the CO2 is a terrible idea. It heavily discounts the future and locks in greater warming. New York should move away from it, and instead set separate targets for CO2 and short-lived climate...
Understanding arXiv Is Key to Modern Digital Culture
This is great I argued something complimentary in the alignDRAW book, that if you don’t know what arXiv is you very likely can’t fully comprehend the last 5 years of digital culture
First AI-Enhanced Edge Computing Space Cruiser Rolls Out
It is our new, high mobility, multipurpose, edge computing, AI enhanced space cruiser. This unit is the first one coming off the assembly line
First Three Months: Your Baby’s Fourth Trimester
The first three months after birth are often called the "fourth trimester" because your baby is essentially still developing outside the womb. Human babies are born more helpless than almost any other primate, partly because our heads are too big...
Atlas 5 Launch Delayed Due to Weather, Vehicle Healthy
ULA is delaying tomorrow's Atlas 5 launch from the Cape because of predicted poor weather. "The launch vehicle and spacecraft are healthy. A new launch date will be provided upon finalization of range approvals and deconfliction with the NASA Artemis...

Blue Ring Highlights GEO-Interplanetary Spacecraft Carrier Glory
Ok. Here she is in all of her GEO-Interplanetary Class, Spacecraft Carrier, glory. The Blue Ring… https://t.co/5iAPBEBKPG
Rethinking Reality: Distance May Not Exist
“And now we have to ask, what is spacetime really? And we know it can’t be as simple as the way we perceive it … I kind of wonder if the next step in really understanding reality is that there’s...

Longevity Is Roughly Half Genetics, Half Lifestyle
You’ve probably heard that longevity is 20% genetics and 80% lifestyle But that would make it an outlier because almost every other human trait is closer to 50% genetic Dr. Uri Alon is a physicist and systems biologist whose recent research suggests...

Biological Age Outperforms Chronological Age in Outcome Prediction
In the era of molecular and organ clocks and marked inter- and infra-individual variability of the aging process, we need to move beyond chronological age. "biologic measures predict outcomes more robustly than chronologic age" @NEJM https://t.co/DKmIfdJJUF https://t.co/d5Gc6xGKqn
Alternate-Day Fasting Worsens Lung Disease in Schistosomiasis
Alternate-Day Fasting Exacerbates Lung Inflammatory Disease Compared to High-Sucrose Diet in Experimental Schistosomiasis Mansoni 🤔"These findings suggest that caloric restriction through ADF aggravates pulmonary disease in schistosomiasis, possibly by enhancing ectopic egg dissemination." https://t.co/FwPjvxC9CI
Blue Ring 1 Advances, Clears Safe‑to‑Mate Test
Blue Ring 1 is coming together nicely and is passing through Safe to Mate testing. Any interest in pictures?

GLP‑1 Drugs Could Help Prevent Cancer, Study Shows
As a medical school professor, I've watched GLP-1 drugs transform diabetes and obesity treatment. Now a Nature Cancer review reveals they may suppress cancer too. GLP-1 drugs reduce insulin resistance, lower inflammation, and cut body weight -- three of the biggest...

TTN's High Mutation Rate Reflects Size, Not Significance
TTN shows up as one of the most mutated genes in almost every cancer exome. New bioinformaticians see it and think they found something. They didn't. It's a 364-exon gene encoding the largest human protein. It collects mutations like a lint...

Sleep Deprivation Triggers Hormone That Fuels Heart Disease
Sleep loss can causally drive heart disease. 1/2) Here's how it works: Sleep loss causes release of a brain hormone (hypocretin) --> goes to bone marrow to simulate the production of inflammatory cells --> these go to arteries and drive atherosclerosis But...
Oral GLP‑1 Battle Heats up Amid FDA Uncertainty
Oral GLP-1 wars, FDA drift, HIV franchise defense, and a few biotech landmines | Ep. 970 https://t.co/sx4kBXzgSL [ 02:30 ] oral GLP-1 battlefield heats up [ 03:08 ] convenience factor drives adoption [ 04:51 ] tolerability issues hit persistence [ 05:45 ] Novo writes $2.1...
Lactate: Misunderstood Molecule, Actually Helps, Not Harms
"Lactate was at the scene of the crime but was not the criminal. It was actually trying to help" Lactate: The Most Misunderstood Molecule in Biology👇 https://t.co/3skDRDEuqw

15‑Minute Walks Cut Heart Risk for Sedentary Adults
Instead of only short bursts of movement, add walks that last 15+ minutes. Among people averaging <8,000 steps/day, those who got most of their daily steps from walks lasting 15+ minutes had the lowest cardiovascular risk and among the lowest mortality...
Urban Bees Rise, Impact on Crops and Natives Debated
While bees are showing up in cities across the US, there’s still a debate about the impact on crops and native bee populations. https://t.co/PQdJuCedsK

Aging Cells Self‑Destruct via ER‑phagy Early
As a medical school professor, I used to teach that aging is gradual wear and tear. But a Vanderbilt study in Nature Cell Biology reveals something far more disturbing. Your cells are actively dismantling themselves through a process called ER-phagy. Starting early...
AI‑Designed Enzymes Signal SynBio’s Sugar‑Reduction Promise
Can synbio solve sugar reduction? The @ArzedaCo + @ManeGroup partnership is a strong signal. AI-designed enzymes Cell-free manufacturing at scale Real products in market Excited to host Alexandre Zanghellini (@biopraxis) at #SynBioBeta2026. Visit the SynBioBeta website to read the full article: https://t.co/1S29MUqfWh
Europe Condemns UK's Self‑inflicted Collapse of Physics Research
A view from Europe on the self-inflicted damage to UK particle, astro and nuclear physics. What a mess this is.
Breakthroughs Spark When Tech Meets Biology, Not Tools
I didn’t expect a piano to make music visible but this does. That caught my attention. Someone spent three years trying to turn sound into something you can see. No AI. No screens. Just experimentation. They tried lasers, smoke, different materials. Nothing worked. Until they found...

Liquid Molecule Stores Sunlight, Releases Heat On Demand
Scientists “Bottle the Sun” With Revolutionary Liquid Battery 🔋 ☀️ https://t.co/OwRj1KreUq 💬 Solar energy has one persistent weakness: it disappears at sunset. Finding a reliable way to store that energy for later use remains one of the biggest obstacles to expanding renewable...

Β‑Hydroxybutyrate's Dual Impact on Colorectal Cancer
β-Hydroxybutyrate, a primary metabolite of ketogenic diets and its dual role in modulating colorectal cancer: from molecular mechanisms to therapeutic insights https://t.co/pPCdm2AcFo https://t.co/mPtz1Xqiep

SIRT6 Loss Triggers Nucleolar Dysfunction and Proteostasis Collapse
SIRT6 Regulates Protein Synthesis and Folding Through Nucleolar Remodeling "Our data suggest that SIRT6 deficiency results in proteostasis loss through nucleolar dysfunction." https://t.co/w1SfUiUxg4 https://t.co/5bqVFfS0lg
Your Voice Reveals Decades‑Ahead Disease Risk
Latent space data helps us understand the geometry of disease (and health). One simple example is our voice. It can predict future risk for cognitive diseases and other health issues, years and decades before you have clinical presentation.
High Cardiovascular Risk Predicts Major Fractures in Postmenopause
A new analysis shows that postmenopausal women with higher cardiovascular risk, as measured by the PREVENT score, are significantly more likely to experience major bone fractures, highlighting a close link between heart and bone health. womenshealth

Repeated Callus Filtering Yields Red Pigment Without
Now THAT is some strong RUBY expression. Filtering transgenic callus a heap of times really pays off. Chasing the red hue without any herbicide or antibiotic pressure. Just hormones to induce callus and careful scalpel work. Some German Chammomile for...
Surface Quasi‑Liquid Layer Boosts Clathrate Growth, Enhances CO₂ Mobility
A quasi-liquid layer at the surface of clathrate hydrates accelerates their growth by enhancing CO2 mobility, offering new insights for applications in gas storage, desalination, and carbon containment. materialsengineering
Teach Students to Guide AI, Not Master Physics
If AI can now solve math, discover physics and chemistry breakthroughs faster than human PhDs, why are we still training humans to be physicists? Serious question. Should education shift from 'learn to do X' to 'learn to direct AI doing...
Health as a Point, Disease as Trajectory in Latent Space
Latent Space as a Physiological Map: All our medical data, genomes, scans, notes are just different shadows of one underlying physiological state. Health = a point in high-dimensional space. Disease = a drifting trajectory Treatment = a vector,...
NASA Reveals Details of Mike Fincke’s ISS Evacuation
NASA released details of the ISS medical evacuation of astronaut Mike Fincke in January 2026 #space #astronomy #science https://t.co/Juis0InB8P
New Therapeutic Triad Accelerates Huntington's Disease Breakthroughs
“Huntington’s Disease and The Triad of Therapeutic Conviction”. Debut blog from Eric Green, CEO of Trace Neuro, explaining why and how advances are happening in HD. Genetics, cellular understanding, and enabling modalities. https://t.co/pAr9EQs5gJ
R3 Bio Engineers Whole Organs, Featured in WIRED
This is so awesome. @JohnSchloendorn and Alice Gilman at R3 Bio talk through what they’re doing at R3 Bio: building something that's never existed before. They're designing genetically engineered whole organ systems. See them featured in WIRED. @WIRED full story here: https://t.co/8z5iGXR0uK
Trump Admin Considers Repurchasing Offshore Wind Leases
The Trump administration is talking with some offshore wind developers about buying back the leases they purchased from the federal government years ago to develop energy projects along the US coast https://t.co/w6VR2H3AC3
Aging Silences Brown Fat's Heat Genes via Epigenetics
Brown fat loses its heat-producing function with age due to epigenetic changes that reduce activity of key genes like PGC1A, with specific enhancers playing a critical role in maintaining this function. https://t.co/Dnnawd5r41
Winter Power Gaps Demand Clean‑Firm Energy and Grid Scale
Solar and wind are making remarkable progress. The day/night cycle will be solved by current economic battery trends. The real long term challenge has always been winter: Those dark winter days or weeks when the wind also fails. For that...
TotalEnergies Drops 2050 Net‑zero Goal
French energy giant TotalEnergies says it will no longer aim to reach net zero emission targets by 2050 https://t.co/oJaqzNTGaQ
SREBP‑2 Links Stress to Cell Death via IRAK1
Researchers found that the cholesterol-related protein SREBP-2 can trigger apoptosis under stress by interacting with IRAK1, revealing a new mechanism for how cells self-destruct. This suggests that beyond telomeres, which signal aging through gradual shortening, cells can also initiate death...
Raw Compute and Data Will Outpace Bio
The Bitter lesson from AI applied to today's Bio AI models tells us most will be washed away with raw compute and data. Today's Startups and Academics will (mostly) fight it but that too will fall. Raw compute and data is what...
Slowing Aging: A Targetable Process for Massive Health Gains
Aging may or may not be classified as a disease, but that’s largely semantics. What matters is that aging is a malleable, targetable biological process, and slowing human aging would result in massive health benefits.
JPMorgan Clients Increasingly Focus on Climate Tipping Points
JPMorgan’s institutional clients have started paying more attention to so-called tipping points in climate https://t.co/MkV9vxVmwj

Plesetsk Launch Planned Early April to 63° Inclination
Local warnings and at least one NOTAM indicate an upcoming launch from Plesetsk between April 1 and 15 to an orbit with an inclination 63 degrees toward the Equator: https://t.co/EhSC0xsQVM https://t.co/E7nBV3xpBV
Dark Energy Keeps Universe Flat Despite Dilution
Ask Ethan: Does dark energy curve the Universe over time? Our Universe was once ruled by radiation and matter, but those densities eventually dilute. Would spatial curvature appear? Even if it did, dark energy now flattens the Universe once again. https://t.co/zF67EySaRB
GLP-1 Drugs: Brain‑targeted Cure for Obesity and Addictions
In 1992, scientists discovered a chemical in Gila monster venom that mimicked GLP-1, the hormone your gut releases to signal fullness. By tinkering with its structure, pharma companies extended its duration from two hours (the Gila monster version) to one...
Artemis II Crew Arrives at KSC for Media Q&A
Artemis II crew is enroute to KSC. Expected to land abt 2:30 pm ET. NASA's Jared Isaacman and CSA's Lisa Campbell will be there to greet them. Crew then will answer questions from the media. Full list of public...