Summit Sparks Breakthroughs: AI, Gene Therapy, CRISPR, mRNA
One thing that really makes the in-person summits we run at STAT so amazing: the people in the room. Here's what happened when we asked some of them for the last big breakthrough they saw. Featuring: the infectious @DrBlytheAdamson, genomcis pioneer @RobertGreene, former FDA CMO and ARCH VC @llborio, biotech leader @ksbosley, and the godfather himself, Stelios Papadopoulos. The answers: AI, gene and cell therapy combined with sequencing babies' DNA, a new take on mRNA vaccines, CRISPR, and data science in health. #STATBreakthrough
Quantum-Centric Supercomputing Accelerates Future Computing Frontier
It was a great pleasure—and truly exciting—to moderate the “Key Dialogue Quantum Technologies” and to listen to the great and impressive talk “Transforming Computing with Quantum-Centric Supercomputing” by @jmchow. His talk at the #GCConference was a wonderful showcase of cutting-edge technology and the...
Nobelium: Synthetic Radioactive Metal Named After Alfred Nobel
How about... No? It's a synthetic, highly radioactive metal, and is the 14th member of the actinide series. Also, it is named after Alfred Nobel. https://t.co/2j8KzgnU9B
Vine-Inspired Robot Lifts Objects with Gentle Precision
This Vine-Inspired #Robot Can Gently Lift Almost Anything by @MIT #Robotics #Engineering #ArtificialIntelligence #Innovation #Technology https://t.co/lfKLB58nJB
NASA Admits Limited Future for Humans in LEO
Pour one out for NASA's Joel Montalbano. Months ago he is confirmed to appear before the US House to speak about the future of humans in low-Earth orbit. On the day before his appearance NASA basically says there isn't much...
NASA Unveils Vision; NOAA Seeks Input on Mission Authorization
As NASA was laying out its new exploration vision yesterday, NOAA's Office of Space Commerce was releasing an update of its Mission Authorization proposal, seeking stakeholder input. https://t.co/zdjJBR62HO https://t.co/7Ly27Fdunk
Japan's Space Museum Makes Planetary Exploration Tangible
Japan’s Space Museum Brings Planetary Exploration to Life by @interesting_aIl #SpaceTech #Tech #Technology #EmergingTech #Space https://t.co/zOaWAd6csZ
Curiosity Fuels AGI: Autonomous Labs Powered by GPT‑5
Awesome being on the @Sequoia Training Data podcast with @gradypb and @sonyatweetybird. Topic links in the 🧵 The most human part of intelligence is curiosity, and science is formalized curiosity. If we want AGI — doing the work of science is...
Bridging Virtual Cells to Real Patients: The Next Frontier
Virtual biology burst onto the scene a few years ago. The idea was simple. Model the cell well enough, and you can predict biology before you test it. Large pharma has been thinking about this longer than most. PK/PD models, systems biology,...
John Martinis' Inclusion Signals US Quantum Boom
I'm in DC this week, talking to legislators about quantum technology, and seeing John Martinis on this list bodes well for quantum research and commercialization in the US!
AI Matches Dermatologists in Melanoma Diagnosis, Study Shows
How good is AI for diagnosing melanoma? A systematic review of 11 studies, 2500 patients, finds accuracy and performance comparable to 50 dermatologists, with promise for broad use requiring further validation @JAMADerm This is important with the big shortage of dermatologists...
Engineered Immune Cells Target Refractory Myeloma, Broader Cancer Potential
Steady progress towards engineering immune cells in the body now for refractory myeloma , with major implications for many autoimmune diseases and cancers https://t.co/K3IksrCFlg https://t.co/1AQ5rLuH1g
Exercise Raises Plaque Yet Cuts Heart Risk
Regular exercise reduces the likelihood of plaque accumulation in the arteries However, many long-term exercisers appear to have coronary artery calcification, indicating atherosclerosis progression The fascinating thing is that despite the higher plaque, those people still have lower rates of cardiovascular disease...
Daily 50‑ton Meteor Rain,
That rock fell from space on Saturday, burst through roof & ceiling, bounced hard enough off the floor to hit the ceiling again, and finally rattled to a stop. It sure surpised the family - thankfully, no one was hurt....
Higher Phenotypic Age Accelerates Cancer Survivors' Mortality Risk
The association between phenotypic age acceleration and the risk of all-cause and cancer mortality among cancer survivors: NHANES 1999–2018 "Our findings reveal a significant linear correlation between PhenoAgeAccel and both all-cause and cancer-specific mortality in cancer survivors." https://t.co/Rt7v8ECOB6
Thousands of P-Values, only a Handful Are Real
1/ You ran 20,000 differential expression tests. 1,000 genes came back with p < 0.05. How many are real? Maybe 50. Maybe fewer. Most bioinformaticians learn p-values in stats class. Almost nobody learns why they break at scale. Let me explain: https://t.co/btC71ABX5N
Roscosmos Unveils First Image From Elektro‑L5 Satellite
Roskosmos published first image from the Elektro-L5 weather satellite which was launched in February. Full size version and context: https://t.co/XRGzszjsAK https://t.co/KYrEHQmwWr
Five Days of 40% Fat Leaves Performance Unchanged
Short-term higher fat intakes do not impair performance 🥑 This new study recruited 20 healthy adults to complete 2 x 5-day diets… 1️⃣ Higher fat diet (40% total energy) 2️⃣ Standard fat diet (30% total energy) Both diets were matched for total calories and...
Kidney Disease Hijacks Gut Microbiome, Accelerating Decline
As a medical school professor, this is one of the most terrifying feedback loops I've seen in medicine. UC Davis researchers just published in Science showing how chronic kidney disease hijacks gut bacteria to destroy your kidneys FASTER. The mechanism: 1. Damaged kidneys...
ISS Captures Progress MS-33 Docking with Antenna Snag
Newly released images taken from the ISS of yesterday's docking with the Progress MS-33 cargo ship, with a stuck antenna clearly visible on the right of docking mechanism. More pics and context: https://t.co/GL29AvnJQ5 https://t.co/7idPQ8z9Ix
India Targets 47% Emissions Cut by 2035
India’s long-delayed new climate policy set a modest target to cut a key emissions metric 47% by 2035, as the world’s third-largest polluter attempts to balance growing energy demand and action on global warming. https://t.co/RKUp7ehe38
2024 Hurricane Season Forecast: 11‑15 Storms Threaten Gulf Coast, Carolinas
The Atlantic hurricane season is expected to produce 11 to 15 named storms with the highest risks along the northern and eastern portions of the US Gulf Coast and the Carolinas, AccuWeather said https://t.co/dYlK2BSpHS
Novo
$NVO triple G drug at 2.16 A1c reduction at only week 24 vs a lower 1.9 A1c reduction at a longer 40 weeks for the max dose of the $LLY triple G. But Novo has no pipeline…? 🤷🏻♂️ https://t.co/CFcnGZGMqt
Hybrid PandaOmics‑Lobster Platform Accelerates Disease Target Discovery
PandaOmics and Lobster hybrid for novel target discovery and disease hypothesis research. @steipete will have serious impact on human life
CRBIOTECH's 2025 Impact Projected to Surge Significantly
📈 The projected 2025 impact of Current Research in Biotechnology is notably higher 🔗https://t.co/HTlbLhpaRc 🌐 #CRBIOTECH #Research #Science https://t.co/DOBMVCJUgC
First PAC‑Bayesian Data‑Dependent Generalization Bounds for Quantum Models
A PAC-Bayesian approach to generalization for quantum models. We take steps towards non-uniform and data-dependent bounds for generalization of quantum machine learning models. https://t.co/czcmNpnD0q In detail, #generalization is a central concept in machine learning theory, yet for quantum models, it is predominantly analyzed...
U.S. Military Pursues True Invisibility for Aircraft
From the TWZ vault: Can The U.S. Military Make An Airplane Invisible To The Naked Eye? https://t.co/En5bCKn8tZ
Intrinsic Human Lifespan Heritability Roughly 50% After Adjustments
Heritability of intrinsic human life span is about 50% when confounding factors are addressed https://t.co/C2je2Dao9T https://t.co/QoGTjAj6Ch
Rapid SARS‑CoV‑2 Evolution Limited by Structural Constraints
SARS-CoV-2 has evolved rapidly since 2019, but its genetic changes remain confined to a limited set of mutations, indicating that strong structural constraints continue to restrict the virus’s evolutionary pathways. genomics
Bio‑Based Membrane Removes 94% of Toxic PFAS
A renewable bio-based polymer membrane efficiently captures and retains over 94% of toxic PFOA from water, offering a reusable and sustainable approach to removing persistent PFAS contaminants. sustainability
D+Q Senolytic Linked to Brain Demyelination, Prompting Safety Concerns
The recent study showing D+Q causes demyelination in brain cells leads to more questions than it answers: (I only read the abstract cause paper new & paywalled.) D+Q has been used a lot in mice & humans. Why hasn't this been noticed...
Lyme Disease Isn’t a Bioweapon, Says Immunology Researcher
Since Lyme Disease is suddenly getting more attention than usual: Hi! I’m a researcher and scientist getting my PhD in Immunology, Infection and Epidemiology. I’ve been studying tick feeding and Lyme Disease for over 5 years now looking for an anti-tick...
NASA Redefines Lunar Exploration Strategy for Future Missions
Last week's EVSN took a closer look at the changing Lunar Exploration landscape. That story provides solid context for today's announcements. I've stuck it up on Medium: https://starstryder.medium.com/closer-look-nasa-rewrites-human-exploration-again-9013f90c7622?sk=ec8e6c25ff5bc4db7eeaab9320db7848
Exercise Protects Blood‑Brain Barrier, Slowing Alzheimer’s
New on exercise —the best medicine vs age-related chronic diseases, a review @Cell_Metabolism https://t.co/z9RpD0SlYW —salutary effect on the blood brain barrier (BBB) vs Alzheimer's and brain aging gift link https://t.co/jmhJwXGWms by @GretchenReynold —original research on BBB integrity via liver produced exercise factor @CellCellPress https://t.co/3tSN8knpYF
Memory Is Constructed, Not Recorded, Says Loftus
Conversation with the brave and brilliant cognitive psychologist Elizabeth Loftus, whose discoveries about the constructive nature of human memory changed the conventional wisdom about eyewitness testimony and recovered memory. Convos About Teaching N & Stuff (I'm not involved). ...
Seeking Enzymes that Decolorize Anthocyanins Like Carotenoid Cleavers
Are there enzymes that cleave anthocyanins into colorless bits? I know there are carotenoid cleavage enzymes that can bite various parts of the saturated chain, but never heard of anthocyaninases... https://t.co/rUHXDWkWvc
Passivating Pinholes Boost TOPCon Solar Cell Efficiency
Discovery of passivating pinholes in TOPCon solar cells paves the way for higher efficiencies #energysky -- via pv magazine global: https://t.co/UWGzf5PaqJ https://t.co/BgyDRVIv7N
NVIDIA GTC Unveils Next‑Gen Radiology Imaging for Doctors
Glimpses of last week’s NVIDIA GTC. A new kind of radiology imaging for doctors. https://t.co/U59b5qmWL9
First Live Moon Crash Broadcast Captivates Millions
#ThisDayInTechHistory. March 24, 1965. Millions watch for the first time as the Ranger 9 space probe crashed into the moon. (NASA) #Space #Exploration #History https://t.co/PFyzWvwTPV
Falcon 1’s First Orbital Attempt Marks 20‑Year Milestone
The first SpaceX orbital launch attempt was 20 years ago today. Ashlee Vance: “the Falcon 1… quite likely changed the course of human history. The imaginations and passions of engineers and dreamers all around the world expanded.” (WTHWOS p.11.) For more Falcon...
Starcloud Launches Orbital Data Center Using NVIDIA H100
NVIDIA-Backed Starcloud Tests Orbital #Data Centers with H100 AI GPU in Space by @IntEngineering #SpaceTech #Tech #Technology #EmergingTech #Space https://t.co/huY6Fk3TU4
Excited to Contribute to Roman Space Telescope Launch
Roman Space Telscope is getting ready to launch this year and I can’t believe I get to work on this awesome mission 🛰️ 🚀 ✨
Asexual Clones Accumulate Mutations, Facing Inevitable Extinction
They cloned a mouse and kept cloning. It went 58 generations before it just couldn't "This model predicts that in asexual lineages, deleterious mutations inevitably accumulate, ultimately producing mutational meltdown and extinction."
Bendable Concrete Promises Safer Buildings in Earthquakes
#WhatsNext? Bendable concrete. Will provide some needed flexibility to structures in earthquake zones. Designed to limit damage to buildings. (Quick Take) #NewMaterials #PublicSafety #Technology https://t.co/g2LlLxqsgB
Lactate: The Most Misunderstood Molecule in Physiology
The lactate story. The Most Misunderstood Molecule in Human Physiology. Coming up tomorrow on Substack https://t.co/cyvmQexhzr
Room‑Temp Ethanol Sensors Using Belt‑Shaped VO₂(B) Crystals
Belt-shaped VO₂(B) single crystals synthesized from V₂O₅ nanofibers demonstrate high sensitivity and selectivity for ethanol detection at room temperature, offering a promising platform for low-power, next-generation gas sensors. materialsinnovation
Google Announces Dual Quantum Computing Platforms
Big news of the day, at Google we are building both superconducting and neutral atom quantum computers. https://t.co/Q8fbzebAyu #quantum #atom #google
Ether Phospholipids Fine‑tune Touch and Temperature Sensing
Specialized ether phospholipids in nerve cell membranes fine-tune sensory receptors, enabling precise detection of touch and temperature by altering membrane tension and fluidity. These findings may inform future approaches to sensory disorders. neuroscience
Particle Accelerators Map Ant Anatomy in New 3D Atlas
Entomologists and particle accelerator physicists have collaborated to produce a new 3D atlas of what makes up an ant, including muscles, nerves, digestive tracts, and exoskeletons. The images are free to access. https://spectrum.ieee.org/3d-scanning-particle-accelerator-antscan
Google Quantum AI Launches Colorado Neutral-Atom Team
If anyone is left on quantum twitter, this is a BIG announcement from the @GoogleQuantumAI group on expanding their footprint in Colorado with a dedicated neutral atom quantum computing team. More details here: https://t.co/5NQduB6Fhm https://t.co/WU0ubqcGS5