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Dual Challenge: Selective IgA Deficiency and Autoimmunity

A recent BMC Pediatrics case study documents a patient with selective Immunoglobulin A (IgA) deficiency who simultaneously developed autoimmune hemolytic anemia. The report details the diagnostic work‑up, highlighting how standard immunoglobulin panels uncovered the dual pathology. Researchers emphasize the rarity of this overlap and explore potential mechanistic links between immunodeficiency and autoimmunity. The findings add a nuanced example to the growing literature on immune system dysregulation.